Clinical trials: Obesity With Complications
Obese, Overweight
Efficacy of a Structured Weight Loss Program in Overweight Women With a History of Recurrent Pregnancy Loss
Overweight and obesity has been associated with a number of adverse pregnancy outcomes in women of reproductive age, including infertility and early pregnancy loss.
- Conditions
- Obese, Overweight, Miscarriage, Recurrent Pregnancy Loss
- Trial name
- NCT01325805
- Testing
- Structured Weight Loss Program, Routine Weight Loss Counseling
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Stanford University
Gestational Diabetes Mellitus, Type 2 Diabetes Mellitus
Combined Liraglutide and Metformin Therapy in Women With Previous Gestational Diabetes Mellitus (GDM)
A diagnosis of gestational diabetes mellitus (GDM)has significant implications for the future health of the mother. GDM is often the culmination of years of unrecognized and unmodified diabetes risk factors that lead to overt and…
- Conditions
- Gestational Diabetes Mellitus, Type 2 Diabetes Mellitus, Metabolic Syndrome, Impaired Glucose Tolerance
- Trial name
- NCT01234649
- Testing
- Metformin XR plus liraglutide
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Woman's
Overweight, Obesity
TOP-mums, for a Healthy Start
This study evaluates the effect of a lifestyle intervention for women with a pregnancy wish who have a high risk on perinatal morbidity because of overweight or obesity.
- Conditions
- Overweight, Obesity, Pregnancy Complications
- Trial name
- NCT02703753
- Testing
- Lifestyle intervention
- Where
- Netherlands
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Intellectual Disability, Neurodevelopmental Disorders
Physical Activity and Community EmPOWERment Project
Purpose: Conduct a wait-list randomized controlled trial (RCT) of an inclusive physical activity program called PACE for adults with intellectual disability (ID) who are not yet showing signs of Alzheimer's Disease…
- Conditions
- Intellectual Disability, Neurodevelopmental Disorders, Autism Spectrum Disorder, Down Syndrome
- Trial name
- PACE (NCT06740162)
- Testing
- PACE Program
- Where
- 2 sites in United States
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Gestational Diabetes Mellitus in Pregnancy, Diet- Controlled, Exercise Addiction
Modulation of the Intestinal Flora With the Probiotic VIVOMIXX™ in Pregnant Women at Risk of Metabolic Complications
The investigators aimed at evaluating the effectiveness of probiotics ingestion in changing maternal microbiota and preventing gestational diabetes in overweight and obese women.
- Conditions
- Gestational Diabetes Mellitus in Pregnancy, Diet- Controlled, Exercise Addiction, High-Risk Pregnancy, Dietary Modification
- Trial name
- NCT02768818
- Testing
- Probiotic VIVOMIXX™
- Where
- Italy
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
Obesity, Pregnancy
Sutures vs. Staples Skin Closure After C-section in Obese Patients
This is a randomized prospective clinical trial designed to determine the wound complication rates for stainless steel staples versus subcuticular suture for skin closure in the obese parturient (BMI≥ 30kg/m2) undergoing cesarean…
- Trial name
- NCT01820221
- Testing
- Suture vs. staples closure method after c-section in obese women.
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Pregnancy Related, Obesity, Maternal
Remotely Monitored Exercise Program in Pregnant Women With Obesity
Pregnant women with obesity will be invited to participate in structured home-based exercise programme, remotely monitored
- Trial name
- GROB (NCT05331586)
- Testing
- Remote Exercise
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Obesity, Polycystic Ovary Syndrome
Mindfulness-based Stress Reduction in Obese Women With Polycystic Ovary Syndrome (PICOS)
The aim of this study was to evaluate the effects of a mindfulness-based stress reduction (MBSR) program on Stress, depression, anxiety, cognitive triad and emotional appetite in obese women with polycystic ovary syndrome (PCOS).
- Conditions
- Obesity, Polycystic Ovary Syndrome, Stress
- Trial name
- NCT06665789
- Testing
- Mindfulness-based Stress Reduction
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Obesity, Infection; Cesarean Section
Skin Incisions and Wound Complication Rates for C-sections in Obese Women
It is the purpose of this study to evaluate the relationship between a low transverse, vertical midline, and supra-panicular high transverse skin incisions and the rate of wound complications in women with a BMI of 40 or greater…
- Conditions
- Obesity, Infection; Cesarean Section, Surgical Wound
- Trial name
- NCT02685761
- Testing
- Midline Vertical, High Transverse
- Where
- 7 sites in United States
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Child Obesity, Insulin Resistance
Supplementation With PUFA´s in Obese Children
Introduction. Insulin resistance (IR) accompanies practically half of children with obesity. This alteration is the border between what can be reversible or permanent.
- Conditions
- Child Obesity, Insulin Resistance, Metabolic Complication
- Trial name
- PUFA (NCT05488223)
- Testing
- AGPI ω-3 (Triple Strength Fish Oil®), AGPI ω-3 + MUFA (avocado oil), MUFA (avocado oil) (1.8g)
- Where
- Mexico
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Maternal Obesity, Obesity
The Developmental Origins of Obesity
Pregestational obesity (PGO, BMI ≥30) is a significant independent risk factor for the development of obesity in childhood and adolescence.
- Trial name
- OMEGA-Stem (NCT06981676)
- Testing
- DHA and EPA
- Where
- Chile
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Obesity, Obesity, Morbid
Comparing Anti-XA Levels in Post-Cesarean Patients Undergoing Enoxaparin Thromboprophylaxis
Pregnant and recently postpartum women are at significantly higher risk of developing a blood clot in their arms or legs known as a deep venous thrombosis (DVT) and/or a blood clot in their lungs known as a pulmonary embolism…
- Conditions
- Obesity, Obesity, Morbid, Pregnancy, Complications; Cesarean Section
- Trial name
- NCT02070237
- Testing
- Enoxaparin
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- MemorialCare Health System
Hyperglycemia, Pregnancy
The Extension of HAPO Follow-up Study
The prevalence of diabetes mellitus (DM) and cardiovascular disease (CVD) escalate remarkably worldwide and obesity becomes an epidemic disease.
- Conditions
- Hyperglycemia, Pregnancy, Overnutrition, Maternal Obesity During Childbirth
- Trial name
- NCT05477511
- Where
- Hong Kong
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Polycystic Ovarian Syndrome, Pelvic Endometriosis
Prevalence of HbA1C in Women With PCOS
Women with PCOS have been observed to be potential diabetics.Recently,American Diabetes Association has suggested screening of women with PCOS for HbA1C.
- Conditions
- Polycystic Ovarian Syndrome, Pelvic Endometriosis, Insulin Resistance, Non-insulin Dependent Diabetes Mellitus
- Trial name
- WHI (NCT01838122)
- Where
- India
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Southern Cross Fertility Centre
Polycystic Ovary Syndrome, Obesity
EQW, DAPA, EQW/DAPA, DAPA/MET ER and PHEN/TPM ER in Obese Women With PolycysticOvary Syndrome (PCOS)
This is a randomized, single-blind, parallel 5 treatment group 24-week trial designed to directly compare the therapeutic effects of exenatide once weekly (EQW), dapagliflozin (DAPA), EQW plus DAPA, combined DAPA/metformin…
- Trial name
- NCT02635386
- Testing
- Exenatide once weekly (EQW ), Dapagliflozin (DAPA), EQW plus DAPA
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Woman's
Pain, Postoperative
The OBstetric Lidocaine Patch (OBLido) Trial
This study will be a single-center, single blind, randomized controlled trial. The study will be conducted at UnityPoint-Health Meriter Hospital under investigators from the University of Wisconsin-Madison.
- Trial name
- OBLido (NCT03810235)
- Testing
- Transdermal Lidocaine Patch
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Polycystic Ovary Syndrome
Short Term Ketogenic Diet in Polycictic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is one of the most common health problems in women of reproductive age, characterized by increased androgen levels, impaired ovulatory functions, and polycystic ovaries.
- Trial name
- NCT06469255
- Testing
- Diet Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Gestational Diabetes, Obesity
Growth Hormone Resistance of Beta-cells A
The purpose of the research study is to better understand how beta-cells (cells in the pancreas that make insulin and help regulate blood sugar) respond to growth hormone in people with a personal history of gestational diabetes…
- Conditions
- Gestational Diabetes, Obesity, Healthy
- Trial name
- GHRB-A (NCT06571487)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Polycystic Ovary Syndrome
Effect of UC Versus EA on Sex Hormones in Obese Infertile Patients With PCOs
The aim of this study is to determine the difference between the effect of Ultrasound Cavitation and Elctroacupuncture on sex hormones in obese infertile patients with poly cystic ovarian syndrome ………………………………………………………………………
- Trial name
- NCT04875312
- Testing
- Ultrasound cavitation in group A, Electro acupuncture in group B
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mohamed Abdel Hamid elgaedy
Therapeutic Procedural Complication
Comparison of Disposcope Endoscope and Fiberoptic Bronchoscope
The fiberoptic bronchoscope (FOB) has been the preferred instrument for many years in the management of difficult tracheal intubation, and it is considered as a gold standard.
- Trial name
- NCT02669550
- Testing
- Fiberoptic bronchoscope, Disposcope endoscope
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Qinhuangdao