Clinical trials: Obesity With Complications
Obesity, Overweight
A Study to Test Whether Survodutide (BI 456906) Helps Chinese People Living With Overweight or Obesity to Lose Weight
This study in China is open to adults who are at least 18 years old who are living with overweight or obesity. People with a body mass index (BMI) of 28 kg/m^2 or higher or 24 kg/m^2 or higher with at least 1 weight related…
- Trial name
- NCT06214741
- Testing
- survodutide
- Where
- 28 sites in China
- Volunteers
- 307 people
- Sponsor
- Boehringer Ingelheim
Obesity, Morbid, Intubation Complication
A Comparison of Vie-Scope and Macintosh Blade Laryngoscopes in Morbidly Obese.
Macintosh laryngoscope is still considered a standard for tracheal intubation, however, visualization of the glottis may be inadequate mainly in morbidly obese patients.
- Trial name
- NCT05502120
- Testing
- Laryngoscopy with Vie-Scope laryngoscope, Laryngoscopy with Macintosh blade laryngoscope
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Lodz
Child Obesity, Insulin Resistance
Supplementation With PUFA´s in Obese Children
Introduction. Insulin resistance (IR) accompanies practically half of children with obesity. This alteration is the border between what can be reversible or permanent.
- Conditions
- Child Obesity, Insulin Resistance, Metabolic Complication
- Trial name
- PUFA (NCT05488223)
- Testing
- AGPI ω-3 (Triple Strength Fish Oil®), AGPI ω-3 + MUFA (avocado oil), MUFA (avocado oil) (1.8g)
- Where
- Mexico
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Atypical Endometrial Hyperplasia, Obese
Liraglutide Plus Megestrol Acetate in Endometrial Atypical Hyperplasia
To investigate the efficacy of liraglutide plus megestrol acetate in obesity patients with atypical endometrial hyperplasia (AEH)
- Conditions
- Atypical Endometrial Hyperplasia, Obese, Fertility Issues
- Trial name
- NCT04683237
- Testing
- Liraglutide Injection, Megestrol Acetate 160 MG
- Sponsor
- Xiaojun Chen
Gestational Diabetes, Obesity
Growth Hormone Resistance of Beta-cells A
The purpose of the research study is to better understand how beta-cells (cells in the pancreas that make insulin and help regulate blood sugar) respond to growth hormone in people with a personal history of gestational diabetes…
- Conditions
- Gestational Diabetes, Obesity, Healthy
- Trial name
- GHRB-A (NCT06571487)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Stress Urinary Incontinence
Effect of Visceral vs Total Body Fat Reduction in Obese Female With Stress Urinary Incontinence
The aim of this study is to investigate the visceral fat reduction versus total body fat reduction on stress urinary incontinence in obese females.
- Trial name
- NCT05944484
- Testing
- low caloric diet, ultrasound cavitation,Kegel exercises
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Dina Mohamed Tarek Mansour El-kasrawy
PCOS
Effect of Dietary Modifacation on Microbiota in Overweight and Obese Polycystic Ovary Syndrome Patients
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting women of reproductive age. The pathogenesis of PCOS is not fully understood.
- Trial name
- NCT03325023
- Testing
- Dietary and life style modification and probiotic Sanprobi Super Formula
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Poznan University of Medical Sciences
Knee Osteoarthristis, Diabetes (DM)
The NTU JO-SMART Study
This study recruits patients with coexisting obesity and knee osteoarthritis (KOA) to implement the NTU-JO Smart Program, an innovative intervention integrating AI-assisted community-based exercise with continuous glucose…
- Conditions
- Knee Osteoarthristis, Diabetes (DM), Obesity & Overweight, Chronic Kidney Disease
- Trial name
- NCT07317310
- Testing
- NTU-JO Smart Program
- Where
- 2 sites in Taiwan
- Volunteers
- 312 people
- Sponsor
- National Taiwan University Hospital
Obesity Associated With Defects in Leptin-melanocortin Pathway
Open-Label Extension Study of Setmelanotide
This is an open-label extension study designed to evaluate the long-term safety and tolerability of continued setmelanotide treatment in male and female patients ≥2 years of age who have completed or transitioned from a previous…
- Trial name
- NCT06596135
- Testing
- Setmelanotide
- Where
- 13 sites in United States
- Volunteers
- 28 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Obese Patients, Bariatric Surgical Pain
Non-opioid Anesthesia Based on Thoracic Paravertebral Block During Laparoscopic Sleeve Gastrectomy
Regional anesthesia is a technique in which a local anesthetic is injected near a nerve or spinal cord to block sensation, motor stimulation, and pain.
- Conditions
- Obese Patients, Bariatric Surgical Pain, Bariatric Surgery (Sleeve Gastrectomy ), Non-Opioid Pain Management
- Trial name
- NCT07084753
- Testing
- Levobupivacaine, Dexamethasone contained in the solution for thoracic paravertebral block, Adrenaline
- Where
- Croatia
- Volunteers
- 36 people
- Sponsor
- IVO JURISIC
Polycystic Ovary Syndrome
The Relationship of PRL and Polycystic Ovary Syndrome (PCOS) in Taiwan's Women
Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder of reproductive-age women. According to Rotterdam 2003 criteria: at least two of three criteria are met, hyperandrogenism, chronic anovulation, and…
- Trial name
- NCT01117272
- Where
- Taiwan
- Volunteers
- 474 people
- Sponsor
- Taipei Medical University WanFang Hospital
Polycystic Ovary Syndrome
Does Vaginal Delivery of Combined Hormonal Contraception Affect the Risk of Metabolic Syndrome in Overweight/Obese Women With PCOS
A prospective study to determine the metabolic effects of the contraceptive vaginal ring among overweight and obese women with polycystic ovary syndrome (PCOS).
- Trial name
- RING-PCOS (NCT04257500)
- Testing
- Etonogestrel/ethinyl estradiol vaginal ring
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Andrea Roe, MD, MPH
Hypertension With Complications and Secondary Hypertension, Overweight and Obesity
Study of the Long-term Effects of Exercise on Heath Indicators in Older People
Cardiovascular diseases (CVD) represent the most frequent cause of death among the elderly population. Hypertension, unfavorable lipid profile, obesity and physical inactivity are among the main risk factors for CVD.
- Conditions
- Hypertension With Complications and Secondary Hypertension, Overweight and Obesity, Lipid Metabolism Disorders, Sarcopenia
- Trial name
- NCT01874132
- Testing
- Exercise training
- Where
- Portugal
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Trás-os-Montes and Alto Douro
Cesarean Section Complications, Anesthesia Complication
Incidence of Complications Associated With Anesthesia in Obesity Parturient Undergoing Cesarean Delivery
The incidence of obesity parturient has been increasing worldwide. There was a report revealing one third of pregnant women in United state considered obesity.
- Conditions
- Cesarean Section Complications, Anesthesia Complication, Obesity, Morbid
- Trial name
- NCT04657692
- Testing
- Anesthesia; general or regional
- Where
- Thailand
- Volunteers
- 527 people
- Sponsor
- Mahidol University
Overweight, Obesity
A Study of Tirzepatide (LY3298176) in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes
We are doing this study to learn more about how tirzepatide may help fight chronic kidney disease in people with obesity with or without type 2 diabetes (T2D). The study will last about 56 weeks and include up to 12 visits.
- Conditions
- Overweight, Obesity, Chronic Kidney Disease, Type 2 Diabetes
- Trial name
- TREASURE-CKD (NCT05536804)
- Testing
- Tirzepatide
- Where
- 27 sites in United States, Austria and 4 more
- Volunteers
- 134 people
- Sponsor
- Eli Lilly and Company
Obesity
A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT)
This study is open to adults who are at least 18 years old and have a body mass index (BMI) of 27 kg/m2 or more. People can take part if they have cardiovascular or chronic kidney disease.
- Trial name
- NCT06077864
- Testing
- survodutide
- Where
- 540 sites in United States, Argentina and 33 more
- Volunteers
- 5,531 people
- Sponsor
- Boehringer Ingelheim
Polycystic Ovary, Obesity
Polycystic Ovary Syndrome and BETATROPHIN
This is an original study giving an information about the association body mass index, polycystic ovary syndrome and betatrophin.
- Trial name
- NCT04448730
- Testing
- serum marker levels
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Hatice Akkaya
Liver Biomarkers, Glucose
Modulatory Effects of Resveratrol Supplement Along With and Without Low Glycemic Index Diet Among Obese Patients With Diabetic Nephropathy
This 12-week randomized controlled trial evaluated the effects of resveratrol supplementation with and without a low glycemic index (LGI) diet in obese patients with diabetic nephropathy.
- Conditions
- Liver Biomarkers, Glucose, Lipid Profiles
- Trial name
- NCT07891975
- Testing
- T0 starch capsule, T1 resveratrol capsule, T2 300 mg per day along with a low glycemic index diet, TWICE A DAY
- Where
- Pakistan
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Obesity With Complications, Morbid Obesity
Bariatric Surgery and Reactive Hypoglycemia
Bariatric surgery has long been recognized as an effective treatment for grade 3 or grade 2 obesity associated with complications.
- Conditions
- Obesity With Complications, Morbid Obesity, Reactive Hypoglycemia, Bariatric Surgery
- Trial name
- NCT01581801
- Testing
- Gastric Bypass, Sleeve Gastrectomy
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Catholic University of the Sacred Heart
Pain, Postoperative
Dexmedetomidine Versus Fentanyl on Postoperative Analgesic Profile in Laparoscopic Sleeve Gastrectomy
Dexmedetomidine (Dex) activates the α2 adrenergic receptor that is present within the locus coeruleus, leading to anxiolysis, hypnosis, analgesia, and sedation.
- Trial name
- NCT06186895
- Testing
- Dexmedetomidine, Fentanyl
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Helwan University