Clinical trials: Obesity and Cardiovascular Risk
Cardiovascular Diseases, Type 2 Diabetes Mellitus in Obese
Implementation of a Peer Leader-facilitated Dyadic Intervention
This Pilot Study Large Application builds upon the results of our prior work to 1) Implement and pilot test a peer leader-facilitated 12-week dyadic intervention (Community Health among Asian Indian immigrants (CHAI) Dyad study)…
- Conditions
- Cardiovascular Diseases, Type 2 Diabetes Mellitus in Obese, Hyperlipidemias
- Trial name
- NCT06643806
- Testing
- CHAI dyad study
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Diabetes, Hypercholesterolaemia
The Effect of Providing Genetic Risk Information on Lifestyle Behaviors in African Americans
Cardiovascular disease (CVD) is a major and persistent health disparity for African Americans. Linking GAINS is a randomized pilot and feasibility study designed to evaluate whether receiving genetic risk information early in a…
- Conditions
- Diabetes, Hypercholesterolaemia, Hypertension, Obesity Type 2 Diabetes Mellitus
- Trial name
- LINKING GAINS (NCT07833384)
- Testing
- Color Genomics Genetic Testing Panels
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Chronic Kidney Diseases, Type 2 Diabetes Mellitus
Prevalence, Incidence and Risk Signature of Chronic Kidney Disease in Sub-Saharan Africa
Chronic kidney disease (CKD) is associated with increased cardiovascular morbidity and mortality. The prevalence of CKD is increasing worldwide and is assumed to also dramatically increase in Sub-Saharan Africa (SSA).
- Conditions
- Chronic Kidney Diseases, Type 2 Diabetes Mellitus, Arterial Hypertension, Obesity
- Trial name
- RenalTWO (NCT05881447)
- Where
- Tanzania
- Volunteers
- 1,200 people
- Sponsor
- Swiss Tropical & Public Health Institute
Overweight, Obesity
Evaluation of a New Orange-Based Beverage Enriched With Polyphenols in Adult Humans
The purpose of this study is to evaluate the effects of a new orange juice-based beverage enriched in fiber and selected phenolic compounds (mainly flavanones) on features of metabolic syndrome and cardiovascular disease risk…
- Trial name
- BIONAOS (NCT01290250)
- Testing
- Orange juice based beverage enriched in polyphenols
- Where
- Spain
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- The Coca-Cola Company
Obesity, Metabolic Syndrome
Weight Loss and Changes in Cardiovascular Risk Markers With a Low Glycemic Diet Compared With a Standard Diet
Overweight and obesity is increasing in most countries, including Norway, and the optimal diet for reducing weight is under discussion.
- Trial name
- NCT00230919
- Testing
- Diet counseling
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Ullevaal University Hospital
Cardiovascular Disease, Hypertension
The GoodNEWS Lifestyle Enhancement Program
This study will train Lay Health Promoters (LHPs) from African-American churches to administer healthy living lessons and activities to their congregations in order to improve overall health and address cardiovascular disease.
- Conditions
- Cardiovascular Disease, Hypertension, Diabetes, Obesity
- Trial name
- GoodNEWS (NCT00669630)
- Testing
- Lay Health Promoter (LHP) with maintenance
- Where
- United States
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Aging, Hypertension
Aging, Nitrate, Endothelial Function and Muscle Oxygenation
Aging has been associated with reduced bioavailability of nitric oxide (NO) and endothelial dysfunction. Beetroot consumption, a nitrate-rich food, has been associated with increased NO bioconversion, which may promote beneficial…
- Conditions
- Aging, Hypertension, Dyslipidemia, Abdominal Obesity
- Trial name
- NCT02772900
- Testing
- Beetroot-based nutritional gel
- Volunteers
- 25 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Fractures
Influence of External Factors on Skeletal Growth in Youth
Objective: Prospective study regulation in bone mass, size, architecture, cortical, trabecular bone, soft tissues and risk factors for cardiovascular disease at growth. Determine regulation by environmental factors.
- Trial name
- NCT00633828
- Testing
- Increased physical education in primary school (daily)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Region Skane
Cardiovascular Disease, High Cardiovascular Risk
A Study to Evaluate the Effect of Long-term Treatment With BELVIQ (Lorcaserin HCl) on the Incidence of Major Adverse Cardiovascular Events and Conversion to Type 2 Diabetes Mellitus in Obese and Overweight Subjects With Cardiovascular Disease or Multiple Cardiovascular Risk Factors
This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group study in overweight and obese subjects with cardiovascular (CV) disease and/or multiple CV risk factors.
- Conditions
- Cardiovascular Disease, High Cardiovascular Risk, Obesity, Overweight
- Trial name
- CAMELLIA-TIMI (NCT02019264)
- Testing
- Lorcaserin hydrochloride
- Where
- 499 sites in United States, Australia and 6 more
- Volunteers
- 14,673 people
- Sponsor
- Eisai Inc.
Hypertension, Obesity
Preparing FIM-BCS - A Lifestyle Modification for African-American Breast Cancer Survivors
Hypertension and obesity are both major risk factors for cardiovascular disease (CVD), a leading cause of death for Black women in the United States.
- Conditions
- Hypertension, Obesity, Nutrition, Healthy
- Trial name
- FIM-BCS (NCT06504914)
- Testing
- Assigned Interventions
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Illinois Chicago
Atherosclerosis, Metabolic Syndrome
Cardiometabolic Risk Factors Registry
CARFARE (CARDIOMETABOLIC RISK FACTORS REGISTRY) is a registry done in the context of a cardiovascular primary prevention program of the Cardiometabolic Unit Officia of the Cardiology Department of the Austral University Hospital.
- Conditions
- Atherosclerosis, Metabolic Syndrome, Diabetes, Cardiovascular Risk Factor
- Trial name
- CARFARE (NCT04040777)
- Where
- Argentina
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Austral University, Argentina
Obesity, Obesity, Abdominal
Effect of Balanced Hypocaloric Diet Associated With Supplementation of Eggplant Meal in the Remission of Cardiovascular Risk Factors
Cardiovascular diseases (CVD) prevail as the main cause of death in developed and developing countries and are among the most frequent causes of disabilities in Brazil and in the world.
- Trial name
- NCT01622309
- Testing
- eggplant meal, cassava meal
- Where
- Brazil
- Volunteers
- 363 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Feeding Behavior, Diet, Reducing
Effects of the Administered Time of Meal on the Treatment of Overweight and Obesity
Objectives: To evaluate the impact of the meal time administered on the body weight of adult individuals of both sexes, being overweight and obese. Experimental design: randomized controlled trial.
- Conditions
- Feeding Behavior, Diet, Reducing, Eating
- Trial name
- NCT03347942
- Testing
- Intervention group, Control group
- Where
- Brazil
- Volunteers
- 110 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Urinary Stones, Hypertension
The Links Between Water and Salt Intake, Body Weight, Hypertension and Kidney Stones: a Difficult Puzzle
Nephrolithiasis is a disease that strikes roughly 10% of the Italian population and its incidence in industrialized countries is on the increase.
- Conditions
- Urinary Stones, Hypertension, Overweight, Obesity
- Trial name
- NCT01100580
- Testing
- low salt diet, water therapy
- Where
- Italy
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Parma
Obesity, Overweight
Tirzepatide vs Semaglutide in Individuals at Cardiovascular Risk But Without Diabetes.
Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials.
- Trial name
- NCT07619508
- Testing
- Tirzepatide, Semaglutide
- Where
- United States
- Volunteers
- 100,000 people
- Sponsor
- Brigham and Women's Hospital
The Focus of Study is to Determine the Waist Circumference Values to Predict Overweight or Obesity
The Sex Specific Waist Circumference Cut Off Points to Predict Overweight or Obesity
The waist circumference (WC) cut off levels of the Caucasian people may not represent the characteristics of different ethnic groups.
- Trial name
- NCT01914640
- Volunteers
- 4,310 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Metabolic Syndrome, Overweight and Obesity
Pediatric Metabolic Syndrome Study
The Pediatric Metabolic Syndrome Study is an observational study being conducted at the Medical University of South Carolina to investigate cardiometabolic risk parameters in obese subjects ages 4 to 21.
- Conditions
- Metabolic Syndrome, Overweight and Obesity, Cardiovascular Risk Factor
- Trial name
- PMSS (NCT03570840)
- Where
- United States
- Volunteers
- 477 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Obesity & Overweight, Cardiovascular Risk Factors
Augmenting Primary Care-Based Obesity Management With the Nutu™ Digital Health Platform
This study evaluates the acceptability and clinical effectiveness of integrating the Nutu™ digital health platform into a comprehensive primary care-based behavioral obesity treatment program using a Zelen randomized controlled…
- Trial name
- NCT07404189
- Testing
- FLOW Program, Nutu™ Offer
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Alabama at Birmingham
Obesity, Cardiovascular Risk Factor
Exercise for Preventing the Metabolic Syndrome in Latinoamerican Amerindians
Despite exercise training decrease blood fasting glicaemy in 'average' terms, there is a wide inter-individual variability after exercise training explored mainly in adults but not in adults with prediabetes comorbidities.
- Conditions
- Obesity, Cardiovascular Risk Factor, Physical Activity
- Trial name
- NCT03653468
- Testing
- Concurrent training (CT)
- Where
- Chile
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidad Santo Tomas
Overweight and Obesity, Cardiovascular Risk Factor
The Emirates Heart Health Project: A Family-based Diet and Exercise Intervention in Obese and Overweight Patients
Data from Abu Dhabi's Department of Health document that the leading cause of death among the population of the emirate of Abu Dhabi is cardiovascular disease (CVD).
- Trial name
- EHHP (NCT04688684)
- Testing
- Family-based diet and exercise intervention
- Where
- United Arab Emirates
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- United Arab Emirates University