Clinical trials: Obesity and Cardiovascular Risk
Hypertension, Hypercholesterolemia
Effects of Purple Vegetables on Cardiovascular Disease (CVD) Risk Factors
The hypothesis is that richly coloured purple vegetables, rich in polyphenolic compounds including anthocyanins will have higher antioxidant and other biological activities, than more lightly coloured versions of these foods.
- Conditions
- Hypertension, Hypercholesterolemia, Type II Diabetes, Obesity
- Trial name
- NCT01564498
- Testing
- vegetable
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Guelph
Cardiovascular-kidney-metabolic Syndrome, Cardiovascular Diseases
Inspire HER: Inspiring the Heart and Emotions for Radical Health
Poor heart health puts Black women at risk for a shorter life with more illness than people of any other non-indigenous racial group.
- Conditions
- Cardiovascular-kidney-metabolic Syndrome, Cardiovascular Diseases, Hypertension, Diabetes
- Trial name
- NCT06966258
- Testing
- Inspire HER Intervention
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Alabama at Birmingham
Microbial Colonization
Motivational Intervention on the Gut Microbiota of Obese Children
Animal models and studies on small samples of obese adults have shown that gut microbial diversity and certain types of bacteria could predict the efficacy of the dietetic treatment to improve body mass index (BMI) and the…
- Trial name
- MICROBEkids (NCT03749291)
- Testing
- Obemat2.0 therapy, Usual Clinical Practice
- Where
- 3 sites in Spain
- Volunteers
- 219 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Obesity, Abdominal, Hypertension
Nursing Intervention in Two Risk Factors of the Metabolic Syndrome and Quality of Life in the Climacteric Period
The estrogenic deficit characteristic of the climacteric stage is accompanied by a high incidence of health problems, such as the presence of Metabolic Syndrome risk factors that contribute to the increase of cardiovascular…
- Conditions
- Obesity, Abdominal, Hypertension, Quality of Life, Menopause
- Trial name
- NCT05387174
- Testing
- : Nursing intervention in two risk factors of the Metabolic Syndrome, abdominal obesity and arterial hypertension and quality of life in the climacteric period.
- Where
- Ecuador
- Volunteers
- 80 people
- Sponsor
- Universidad de Concepcion
Cardiovascular Risk Factors, Insulin Resistance
Pilot Validation of the STELA Preventive Medicine Platform to Reduce Modifiable Health Risk Factors in Adults (CPM-STELA)
This study evaluates a comprehensive digital health platform called STELA, developed at the Center for Preventive Medicine (CPM) of AGEL Hospital Trinec-Podlesi in Czechia.
- Conditions
- Cardiovascular Risk Factors, Insulin Resistance, Obesity, Dyslipidemias
- Trial name
- CPM-STELA (NCT07551960)
- Testing
- STELA Digital Preventive Medicine Platform, Comprehensive Preventive Health Assessment
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nemocnice AGEL Trinec-Podlesi a.s.
Obesity
Growth Hormone, Cardiovascular Risk, and Visceral Adiposity
This study will compare growth hormone levels and cardiovascular risk markers in normal weight and overweight women and men. In women and men with increased abdominal weight, growth hormone (GH) versus placebo will be…
- Trial name
- NCT00131378
- Testing
- Nutropin AQ growth hormone
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cardiovascular Disease
Effects of Almonds on Cardiovascular Risk Factors
The purpose of this research is to build the evidence base for approval of FDA health claims related to almonds and cardiovascular disease.
- Trial name
- ALD (NCT01101230)
- Testing
- Almonds
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Penn State University
Cardiovascular Risk Factor and Kidney Related Biomarkers
Omega-3 and Cardiovascular Risk Factors and Kidney Related Biomarkers
In this study, 99 overweight or obese women that referred to the Clinic Nutrition to lose weight were randomly divided into three groups according to body mass index (BMI) by random-number table (figure1).
- Trial name
- NCT03197220
- Testing
- fish, walnut, fish-walnut
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Pre-eclampsia, Obesity
ESTEEM - Effect of Simple, Targeted Diet in Pregnant Women With Metabolic Risk Factors on Pregnancy Outcomes
Obesity is a growing problem in East London and every other woman who enters pregnancy is obese or overweight. In addition to obesity, other metabolic risk factors such as raised lipids, high blood pressure and diabetes increase…
- Conditions
- Pre-eclampsia, Obesity, Raised Lipids, High Blood Pressure
- Trial name
- ESTEEM (NCT02218931)
- Testing
- Targeted ESTEEM diet, Non-randomised cohort
- Where
- United Kingdom
- Volunteers
- 3,442 people
- Sponsor
- Queen Mary University of London
Obesity
Effect of Wholegrain Wheat on Body Weight and Composition and Cardiovascular Risk
The aim of this study is to investigate the potential beneficial effect of wholegrain on body weight and composition as well as cardiovascular risk in overweight women.
- Trial name
- HEALTHGRAIN (NCT00869531)
- Testing
- wholegrain, refined wheat
- Where
- Denmark
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Subclinical Atherosclerotic Cardiovascular Disease, Blood Pressure
Extracellular RNAs in Relation to Cardiometabolic Risk
Background: Extracellular RNAs (exRNAs) send genetic data from cell to cell. This is how they affect the way cells communicate with each other. There are many types of exRNA, and they each serve different roles.
- Conditions
- Subclinical Atherosclerotic Cardiovascular Disease, Blood Pressure, Obesity
- Trial name
- NCT03225196
- Where
- United States
- Volunteers
- 4,495 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hyperlipidemias, Overweight and Obesity
Pilot Study on the Effects of a Plant-Strong Diet on Cardiovascular Risk Factors
The purpose of this study is to conduct a preliminary test of the effectiveness of various educational interventions to promote adoption of a whole-food, plant-strong diet and reduce specific cardiovascular risk factors in…
- Conditions
- Hyperlipidemias, Overweight and Obesity, Diabetes
- Trial name
- NCT03330548
- Testing
- TeleMOVE!, Culinary Rx
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Phoenix VA Health Care System
Dyslipidemia, Overweight and Obesity
Intermittent Cottonseed Oil Consumption
Cardiovascular disease risk factors, including higher BMIs and poor cholesterol profiles, are on the rise and contribute to the United States' growing disease burden.
- Conditions
- Dyslipidemia, Overweight and Obesity, Nutrition, Healthy
- Trial name
- NCT07246408
- Testing
- CSO-30, CSO-20, Control
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Obesity
On-Line Intervention For Promoting Healthy Habits And Weight Loss In Hypertensive Patients
Efficacy of an Internet-based self-guided intervention for promoting healthy habits and weight loss in hypertensive people with overweight and obesity: A Randomized Controlled Trial
- Trial name
- VIVIR-MEJOR (NCT02445833)
- Testing
- Lifestyle on-line intervention
- Volunteers
- 106 people
- Sponsor
- Universitat Jaume I
Body Mass Index Quantitative Trait Locus 8 Disorder, Tangier Disease
High Protein Weight Loss Diet, High Sensitivity C-Reactive Protein and Cardiovascular Risks Among Obese Women
The investigators aimed to determine the effects of HP diet on CVD risk factors and hs-CRP among overweight and obese women.
- Trial name
- NCT01763528
- Testing
- nutrition intervention
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Obesity
ProduceRx: Improving Weight and Cardiovascular Risk in Adults With Food Insecurity and Obesity
This is a pilot randomized controlled trial to assess the effects of providing produce vouchers during behavioral weight loss treatment in 40 adults with obesity and food insecurity.
- Trial name
- NCT05362747
- Testing
- Behavioral weight loss and produce vouchers
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Hyperglycemia, Postprandial, Overweight and Obesity
Ketone Supplementation, Glucose Control, and Cardiovascular Function
Post-prandial hyperglycemic excursions induce a cascade of deleterious effects on the body, including increased inflammation, production of reactive oxygen species, and impaired cardiovascular function.
- Conditions
- Hyperglycemia, Postprandial, Overweight and Obesity, Diabetes Mellitus Risk
- Trial name
- NCT03817749
- Testing
- Exogenous ketone monoester
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of British Columbia
Metabolic Syndrome, Hypertension
Development and Multicenter Validation of an AI-Based Remote Photoplethysmography (rPPG) Facial Scan for Multimodal Health Assessment
The goal of this observational study is to learn if a non-contact facial scan using artificial intelligence (AI) can be used to check health status in adults living in urban areas such as Jakarta.
- Conditions
- Metabolic Syndrome, Hypertension, Diabetes (DM), Tachycardia
- Trial name
- NCT07491978
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tarumanagara University
Sleep, Cardiovascular Disease
Impact of Sleep Restriction in Women
The overall goal of this project is to test the hypothesis that long-term, sustained sleep restriction (SR), in women, will lead to increased cardio-metabolic risk.
- Conditions
- Sleep, Cardiovascular Disease, Obesity
- Trial name
- NCT02835261
- Testing
- Sleep Restriction
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Columbia University
Physical Activity, Overweight
Intervention Centered on Adolescents' Physical Activity and Sedentary Behavior (ICAPS)
Physical activity is thought to be a key element in preventing the obesity epidemic and the associated cardiovascular and metabolic diseases.
- Conditions
- Physical Activity, Overweight, Cardiovascular Disease
- Trial name
- ICAPS (NCT00498459)
- Testing
- Physical activity
- Where
- France
- Volunteers
- 954 people, healthy volunteers welcome
- Sponsor
- Louis Pasteur University, Strasbourg