Clinical trials: Obesity in Adolescents
Pediatric Obesity, Executive Function
Virtual Health Focused Acceptance-Based Program for Parents and Youth
The main purpose of vHAPPY is to pilot test a new type of virtual family-based healthy lifestyle program for children aged 8-14 with obesity and their caregivers.
- Trial name
- vHAPPY (NCT04634045)
- Testing
- Web Based Treatment
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Alabama at Birmingham
Overweight, Family Relations
Reducing Obesity Health Disparities in Hispanic Youth
The proposed study will evaluate the efficacy of a family-based obesity prevention intervention in increasing physical activity and improving the quality of dietary intake among Hispanic Youth.
- Conditions
- Overweight, Family Relations, Adolescent Behavior, Drug Use
- Trial name
- NCT03943628
- Testing
- Familias Unidas
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- University of Miami
Adolescent Obesity, Insulin Resistance
Breakfast Omission and Energy Balance in Girls
There is a distinct lack of experimental evidence on whether breakfast consumption and omission affect energy balance-related variables.
- Conditions
- Adolescent Obesity, Insulin Resistance, Adolescent Behavior
- Trial name
- NCT04481776
- Testing
- Breakfast consumption, Breakfast omission
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Bedfordshire
Obesity, Childhood
Mechanisms of Obesity and Its Metabolic Complications in Youth
The overarching goal of this project is to determine whether the effect of gut microbiota on human metabolism might be mediated by short chain fatty acids (SCFA) and whether the SCFA might modulate lipid metabolism.
- Trial name
- NCT03454828
- Testing
- obese carbohydrate diet, lean carbohydrate diet
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Yale University
Cardiovascular Diseases, Heart Diseases
Anger and Cardiovascular Risk in Urban Youth
To examine anger and cardiovascular disease risk in urban youth. The project studied patterns of hemodynamic responses to social and nonsocial stressors, ambulatory blood pressure (BP), fasting insulin, fasting glucose, lipid…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension, Obesity
- Trial name
- NCT00005383
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Polycystic Ovary Syndrome
A Cooking and Eating Study
Background. The polycystic ovary syndrome (PCOS) is a complex hormonal disorder that presents in susceptible girls around the time of menarche. Females with PCOS have high levels of androgens (e.g., testosterone).
- Trial name
- ACES (NCT01079845)
- Testing
- Nutrition Education, Dietary Counseling, and Cooking
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Boston Children's Hospital
Physiological Response to Exercise, Perception of Exercise Difficulty
Perception of Physical Exertion in Healthy Weight and Obese Adolescents
Little is known regarding the relationship between perceived and physiological exertion in adolescents. The purpose of this study is to investigate the association between physiological and perceptual markers of effort during…
- Trial name
- NCT01695785
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Overweight, Obesity
Electronic Health Technology for Assessment of Physical Activity and Eating Habits in Children and Adolescents Who Are Overweight and Those With Obesity
Aims: During the last decades overweight/obesity has increased markedly. They are associated with a high risk for diabetes and death. Effective intervention is mandatory.
- Trial name
- NCT01138293
- Testing
- motion detection with a motion sensor
- Where
- Germany
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- MEDIGREIF Inselklinik Heringsdorf
Insulin Resistance, Insulin Sensitivity
Calcium, Vitamin D and Metformin to Treat Insulin Resistance in Obese African American Adolescent Females
This is a feasibility study to examine the treatment with Metformin, vitamin D with calcium supplement for insulin resistance in obese, black, female teens.
- Conditions
- Insulin Resistance, Insulin Sensitivity, Obesity, Vitamin D Deficiency
- Trial name
- NCT01107808
- Testing
- Calcium and Vit D, Metformin, Vit D and Calcium
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Physical Activity, Sedentary Lifestyle
Pilot Data Collection for Activity, Adiposity, and Appetite in Adolescents
The goal of this study is to quantify energy metabolism using indirect calorimetry at rest, in the presence of excess energy following a meal, and in response to the demand for energy during exercise.
- Conditions
- Physical Activity, Sedentary Lifestyle, Metabolism, Energy Balance
- Trial name
- AAAA (NCT03157063)
- Testing
- Data Collection Procedures
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Obesity
Brazil Nut Consumed on the Metabolic Profile, Oxidative Stress and Nutritive Microcirculatory Patterns
The purpose this research is to check if Brazil Nuts consumed improvement the metabolic profile, state redox and endothelial function in obese adolescents.
- Trial name
- NCT00937599
- Testing
- Brazil Nut
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- Rio de Janeiro State University
Overweight and Obesity
FRESH-TEEN: Families Responsibility Education Support Health for Teens
The objective of this proposed study is to collect initial efficacy data on a behavioral weight loss (BWL) program for teens, which also includes emotion regulation strategies (ER), to standard BWL.
- Trial name
- FRESH-TEEN (NCT03674944)
- Testing
- Behavioral Weight Loss (BWL) + Emotion Regulation (ER), Behavioral Weight Loss (BWL)
- Where
- 2 sites in United States
- Volunteers
- 332 people
- Sponsor
- University of California, San Diego
Obese Adolescents, Mental Health
Co-creating School Community Intervention Program on Physical Activity to Increase Health Equity in Children and Adolescents
The goal of this observational and interventional study is to understand whether environmental and behavioral interventions can improve physical activity and health outcomes in children aged 12-16 years attending VDU Atžalynas…
- Trial name
- Connection (NCT07120516)
- Where
- Lithuania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sandra Andrusaityte
Overweight
Barriers to Effective Weight Loss in Overweight Adolescents
The current study aims to investigate the impact of a comprehensive, team-based, family-centered, lifestyle modification program on body weight, metabolic abnormalities, fitness measures, and self-esteem in overweight adolescents…
- Trial name
- TEENS (NCT00562263)
- Testing
- Lifestyle modification
- Where
- United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
PreDiabetes, Obesity
Clinical Trial of Crocus Kozanis Administration in Obese Children and Adolescents
The study aims to investigate possible effects of per os Crocus Kozanis administration in children and adolescents with obesity
- Conditions
- PreDiabetes, Obesity, Dyslipidemias
- Trial name
- NCT05572749
- Testing
- Crocus Kozanis, Metformin
- Where
- Greece
- Volunteers
- 75 people
- Sponsor
- Aristotle University Of Thessaloniki
Obesity, Obstructive Sleep Apnea Syndrome
Pilot Study to Assess the Effectiveness of Tonsil and Adenoidectomy (T+A) in Overweight Children and Adolescents
Obesity has reached epidemic proportions in the United States with roughly 20% of American children being overweight and has serious consequences such as sleep apnea.Additionally, obesity is known to result in the earlier onset…
- Trial name
- NCT00222963
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Rochester
Obesity, Cardiovascular Diseases
High-intensity Exercise Training or Multidisciplinary Treatment in Extremely Obese Adolescents
The aim of the present study was to determine the effects of a multidisciplinary approach and intensity-controlled interval training on cardiovascular risk factors in overweight adolescents
- Trial name
- NCT00682266
- Testing
- intensity controlled interval training (AIT), Multidisciplinary approach (MTG)
- Where
- Norway
- Volunteers
- 54 people
- Sponsor
- Norwegian University of Science and Technology
Obesity/Therapy
Brain Plasticity and GLP-1 Receptor Agonist Treatment for Obesity
Glucagon-like peptide 1 receptor agonists (GLP-1RA), such as Ozempic and Wegovy, have been rapidly adopted for the treatment of obesity in both youth and adults.
- Trial name
- PLASTIC (NCT07021937)
- Testing
- Semaglutide 1.7mg subcutaneous
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Colorado, Denver
Pediatric Obesity
The Peds Obesity Study
The aim of the study is to investigate, in severely obese adolescents, the effects of a high protein, restricted carbohydrates utilizing partial meal replacements diet (HPRC-PMR) on weight loss, body composition, and bio-chemical…
- Trial name
- NCT02353637
- Testing
- Partial Meal Replacements
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Florida
Adiposity, Childhood Obesity
Early Life Intervention in Pediatrics Supported by E-health
Childhood obesity in early life contributes to the development of specific NCDs, i.e. adult obesity. Unhealthy diet and low level of physical activity are lifestyle risk behaviors associated with chronic, systemic inflammation…
- Conditions
- Adiposity, Childhood Obesity, Adolescent Obesity, Non-communicable Disease
- Trial name
- ELIPSE-I (NCT06208345)
- Testing
- Life-Style app
- Where
- Switzerland
- Volunteers
- 148 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern