Clinical trials: Obesity in Diabetes
Peripheral Artery Tonometry, Diabetes
Peripheral Artery Tonometry in Children With Type 1 Diabetes and Obese Children
Background: The reactive hyperemia-peripheral artery tonometry (RH-PAT) is a newly developed method for noninvasive endothelial function assessment.
- Conditions
- Peripheral Artery Tonometry, Diabetes, Children, Obesity
- Trial name
- NCT01267591
- Where
- Belgium
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Diabetes Mellitus, Type 2
Impact of High Protein and Low Carbohydrate Smoothie Drinks in Type-2 Diabetes Mellitus
We compared between a regular high protein or a high protein and low carbohydrate smoothie drinks with conventional diabetic enteral drinks (Glucerna) on glucose homeostasis, insulin and lipid metabolism in type 2 diabetic and…
- Trial name
- NCT04577274
- Testing
- smoothie with regular formulas (SM), smoothie with low carbohydrate formulas (SMLS), conventional diabetic enteral drinks (Glucerna)
- Where
- Thailand
- Volunteers
- 43 people
- Sponsor
- Mahidol University
Chronic Diseases, Hypertension
Collection of Blood and Urine Specimens From Volunteers Utilizing Health Examination Services
In summary, the researchers want to construct a longitudinal data bank using voluntary health examination participants. Researchers in the National Taiwan University Hospital (NTUH) campus can utilize these data to clarify the…
- Conditions
- Chronic Diseases, Hypertension, Diabetes, Obesity
- Trial name
- NCT00173940
- Where
- Taiwan
- Sponsor
- National Taiwan University Hospital
Obesity, Non-Alcoholic Fatty Liver Disease
Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity (ATM)
The goal of this study is to evaluate the role of transcription factor EB (TFEB) in adipose (fat) tissue macrophages (ATM) in regulating adipose tissue and systemic metabolic function in obesity.
- Conditions
- Obesity, Non-Alcoholic Fatty Liver Disease, Diabetes Mellitus, Type 2, Healthy
- Trial name
- ATM (NCT06571474)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bettina Mittendorfer
Hypercholesterolemia, Obesity
The Impact of Using a Smartphone Health Application in the Improvement of Cardiovascular Disease Risk Factors
This study investigates the effectiveness of Mobile health application (mHealth apps) in the improvement of cardiovascular disease risk factors including metabolic and behavioral factors.
- Conditions
- Hypercholesterolemia, Obesity, Diabetes Mellitus, Hypertension
- Trial name
- NCT05798442
- Testing
- smartphone health application (Opulse)
- Volunteers
- 410 people
- Sponsor
- Sultan Qaboos University
Metabolic Syndrome, Obesity
Reduction of the Metabolic Syndrome in Navarra-Spain
The purpose of this study is to determine whether a dietary pattern based on crononutrition and dietary training, together with dietary and psychological control, can reduce the body weight, improve the oxidative and inflammatory…
- Conditions
- Metabolic Syndrome, Obesity, Diabetes, Cardiovascular Disease
- Trial name
- RESMENA-S (NCT01087086)
- Testing
- Crononutrition, American Heart Association
- Where
- Spain
- Volunteers
- 109 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Prediabetic State, Cardiovascular Diseases
Role of Aging and Individual Variation in Exercise Training Responsiveness
The primary purpose of this study is to assess the effects of aging on markers of physical reserve and exercise-induced adaptations in resilience in older adults who completed a structured exercise program within the last 15…
- Conditions
- Prediabetic State, Cardiovascular Diseases, Insulin Resistance, Obesity
- Trial name
- STRRIDE IV (NCT06471569)
- Testing
- Low/Mod, High/Mod, High/Vig
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Duke University
Obesity, Type 2 Diabetes
Effects of Stevia on Satiety and Eating Attitudes in Healthy, Overweight and Obese Adults
The purpose of this study is to test the effects that three different types of sweeteners have on food intake, hunger and satiety levels, as well as insulin and glucose measures.
- Trial name
- NCT01115088
- Testing
- Aspartame, Sucrose, Stevia
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Diabetes
Mindful Eating Study for Adults With Diabetes and Weight Concerns in Hong Kong
Objectives: To assess the effect of a digital Mindfulness-Based Eating Awareness Training (MB-EAT) intervention on anthropometric measures, glycaemic control, eating behaviours, psychological health and hormones regulating stress…
- Trial name
- NCT07692386
- Testing
- MB-EAT, control group
- Where
- Hong Kong
- Volunteers
- 120 people
- Sponsor
- The Hong Kong Polytechnic University
Obesity, Type 2 Diabetes
Creation of Side-to-Side Compression Anastomosis Using the GT Metabolic Solutions DI Biofragmentable Magnetic Anastomosis System in Mexico
The purpose of this clinical research study is to evaluate the feasibility / performance, safety and initial efficacy of the GT Metabolic Solutions DI Biofragmentable Magnetic Anastomosis System (MAGNET System, DI…
- Trial name
- NCT07085741
- Testing
- MAGNET System, DI Biofragmentable
- Where
- Mexico
- Volunteers
- 10 people
- Sponsor
- GT Metabolic Solutions, Inc.
Obesity
Effects of Roflumilast on Insulin and Blood Sugar Levels in Prediabetic Overweight and Obese Individuals
Background: Roflumilast is a drug used to treat chronic obstructive pulmonary disease (COPD). It is designed to help reduce lung inflammation.
- Trial name
- NCT01862029
- Testing
- Roflumilast
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Type 2 Diabetes, Obesity
The Aboriginal Youth Mentorship Program
Building on the successes of a communal, relationship based approach to Aboriginal youth mentoring in an after school physical activity program (AYMP), the investigators are evaluating a peer-led approach for diabetes prevention.
- Trial name
- AYMP (NCT01820377)
- Testing
- Aboriginal Youth Mentorship Program
- Where
- Canada
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Prediabetes
Examining the Effects of Diet on Health in Prediabetes With an Online Program
The study is a pilot, designed to provide data regarding the feasibility and acceptability of conducting such a study on a larger scale.
- Trial name
- NCT02188823
- Testing
- Low carbohydrate diet
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of California, San Francisco
Type2 Diabetes, Obesity
PGC-1 & MUSCLE MITOCHONDRIAL DYSFUNCTION IN DIABETES: AIMS 1-4
We are trying to understand how insulin (a type of hormone in the body that regulates how the body regulates how one metabolizes protein and carbohydrates) and exercise alter proteins involved in energy production and metabolism…
- Trial name
- NCT03323788
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Arizona
Cardiovascular Risk Factors, Hypertension
Clinical Management of Cardiovascular Risk Factors in Adult Patients: A Before-and-After Interventional Study
This study aims to evaluate cardiovascular risk factors, clinical characteristics, and outcomes in adult patients attending an outpatient cardiology clinic.
- Conditions
- Cardiovascular Risk Factors, Hypertension, Dyslipidemia, Type 2 Diabetes Mellitus
- Trial name
- CV-RISK (NCT07447362)
- Testing
- Structured Cardiovascular Risk Management
- Where
- Chile
- Volunteers
- 220 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Peer Support and Chronic Disease, Obesity
Peer Support Dyads in Churches
The purpose of this study is to explore how working with a partner can influence participation in a church wellness program. There are many different types of church wellness programs.
- Conditions
- Peer Support and Chronic Disease, Obesity, Type II Diabetes, Cardiovascular Disease
- Trial name
- NCT03463941
- Testing
- Peer Support Dyad Intervention
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Duke University
Type 2 Diabetes, Obesity
A Study to Evaluate the Postprandial Metabolic Response After Use of Glucerna SR in Obese Type 2 Diabetes
This is a phase 4, 24-week, randomized, parallel, open-label study of a meal replacement program with Glucerna SR in obese Asian participants with type 2 diabetes.
- Trial name
- NCT00631774
- Testing
- Glucerna SR
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Overweight, Obesity
Correlation of Irisin and Adipokine Levels With Body Mass Index and Risk Factors for Metabolic Syndrome in Hispanic Children
Childhood obesity is one of the most serious global public health challenges of the 21st century (Daniels et al., 2009). Mexico has the highest prevalence of obesity, (Secretaría de Salud, 2009); 34.4% of children and 35% of…
- Conditions
- Overweight, Obesity, Thinness
- Trial name
- NCT02320110
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Instituto Tecnologico y de Estudios Superiores de Monterey
Diabetes Prevention, Obesity Prevention
PERFECT Project - Part 2 - Study 2
The objectives are to test the acute effects of different cereals containing pulse ingredients on: 1) aerobic endurance and substrate oxidation during exercise 2) response of blood glucose, insulin and appetite to an aerobic…
- Trial name
- NCT02370927
- Testing
- Control, Pea protein, Pea Starch
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Obesity
Vestibular Stimulation to Trigger Adipose Loss (VeSTAL) Clinical Trial
A randomized, double blind sham controlled clinical trial to evaluate the efficacy of vestibular nerve stimulation (VeNS), combined with a lifestyle modification program, compared to a sham control and a lifestyle modification…
- Trial name
- VeSTAL (NCT03640286)
- Testing
- VeSTAL
- Where
- 4 sites in United States, United Kingdom
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Neurovalens Ltd.
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