Clinical trials: Obesity in Diabetes
Psoriasis, PreDiabetes
Effect of Addition of Pyramidal Exercise to Intermittent Fasting on Dryness of Eye in Pre-diabetic Psoriasis Patients
insulin resistant psoriatic obese patients may complain problems of dryness of eye. Intermittent fasting may improve dryness of eye, obesity, insulin resistance, and psoriasis.
- Conditions
- Psoriasis, PreDiabetes, Obesity, Dry Eye
- Trial name
- NCT06893913
- Testing
- pyramidal training plus intermittent fasting, intermittent fasting
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Type 2 Diabetes Mellitus (T2DM)
Interventional Study of Active Weight Management in Patients With Type 2 Diabetes and Obesity in Routine Clinical Practice During 12 Months.
This study was aimed to achieve of long-term weight loss in T2DM patients by use of comprehensive lifestyle changes program, providing patients with structured diet, exercise plan, group behavioral support and group education.
- Trial name
- NCT02670928
- Testing
- Lifestyle intervention
- Where
- 2 sites in Russia
- Volunteers
- 130 people
- Sponsor
- Novartis Pharmaceuticals
Diabetes, Diabetes Mellitus, Type 2
Comparison of the Change in Fat Distribution in Overweight and Obese Subjects With Type 2 Diabetes After Insulin Treatment
This trial is conducted in Europe. The aim of this clinical trial is to compare the change in trunk fat mass, assessed by Double Energy X-ray Absorptiometry (DEXA) after 26 weeks of treatment with insulin detemir or insulin NPH…
- Trial name
- NCT00795600
- Testing
- insulin detemir, insulin NPH
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Novo Nordisk A/S
Obesity, Type 2 Diabetes Mellitus
Effect of Pre-meal Serving of Dairy and Dairy Alternatives on Post-meal Satiety and Glycaemia in Healthy Young Adults
Regular consumption of dairy products is found to negatively associated with metabolic diseases and improve body composition in long term studies and has positive effect on acute glycemia control and satiety.
- Trial name
- NCT04600128
- Testing
- Dairy-based greek yogurt, Dairy-based cheddar cheese, Plant-based yogurt
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Metabolically Unhealty Obese, Dyslipidemia
Effect of a Low-Calorie MCT-Rich Traditional Minangkabau Diet on Obese Individuals
This study aims to investigate the effect of a low-calorie diet rich in medium-chain triglycerides (MCTs) based on traditional Minangkabau foods on metabolic biomarkers in individuals with obesity.
- Conditions
- Metabolically Unhealty Obese, Dyslipidemia, Diabetes (DM), Resistance, Insulin
- Trial name
- NCT07423884
- Testing
- Low-Calorie Diet Rich in Medium-Chain Triglycerides (MCTs) Based on Traditional Minangkabau Foods
- Where
- Indonesia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Andalas University
Isolated Impaired Fasting Glucose
HIIT in Isolated IFG: A Proof-of-Concept Study
This pilot randomized controlled trial will involve 34 physically inactive adults aged 35-65 years with overweight or obesity and isolated impaired fasting glucose (i-IFG).
- Trial name
- NCT06143345
- Testing
- High-intensity interval training and eucaloric diet, No intense physical activity and eucaloric diet, Continuous glucose monitoring (CGM) (Dexcom G6 Pro CGM sensor)
- Sponsor
- Emory University
Dry Eye Disease (DED), Diabete Mellitus
Impact of GLP-1 Receptor Agonists on Dry Eye Disease in Patients With Type 2 Diabetes Mellitus and Obesity
Diabetes mellitus (DM), prediabetes, and obesity are emerging as major global public health problems, with their epidemic spread continuously increasing over the past decades.
- Conditions
- Dry Eye Disease (DED), Diabete Mellitus, GLP-1, Ocular Surface
- Trial name
- GALENOS (NCT07605572)
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Attikon Hospital
Heart Diseases, Diabetes Mellitus
Adiposity and Fat Patterning in Black Americans
To examine the relationships of obesity and fat patterning with morbidity and mortality in Black Americans.
- Conditions
- Heart Diseases, Diabetes Mellitus, Obesity
- Trial name
- NCT00005248
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Diabetes Mellitus, Type 2, Nutrition Disorders
Comparison of a Plant Protein Diet to a Animal Protein Diet Emphasized in Type 2 Diabetics
This 6-week parallel randomised prospective dietary intervention study with type 2 Diabetes investigates the nutrition influence of animal protein in comparison to plant protein on the glucose metabolism.
- Conditions
- Diabetes Mellitus, Type 2, Nutrition Disorders, Obesity, Body Weight
- Trial name
- LeguAN (NCT02402985)
- Testing
- High animal protein diet group, High plant protein diet group
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- German Institute of Human Nutrition
Diabetes Mellitus Type 2
Effect of High Intensity Interval Training and Ultrasound Cavitation on Lipid Profile in Type 2 Diabetes Patients
The study aim to find out the combined effect of high intensity interval training and ultrasound cavitation on lipid profile in type two diabetic patient with abdominal obesity.
- Trial name
- Diabeties (NCT06926725)
- Testing
- Cavitation : Study group A only will receive one session per week for three months (total 12 sessions ). Ultrasound treatments are performed using an applicator head with diameter 7 cm . Intensity :, high intenisty exercise, Diet
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Mahmoud Awad Ramadan Elkholy
Obesity
The Study of Inflammation on Blood Glucose Levels in Obese People
Chronic subaccute inflammation may underlie the development of diabetes cardiovascular disease and other components of the metabolic syndrome.
- Trial name
- NCT00258115
- Testing
- salsalate
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Joslin Diabetes Center
Obesity, Diabetes
Effect of a Treatment of Lifestyle Changes on the Prevalence of Metabolic Syndrome and Body Weight in Mexican Women
The metabolic syndrome is a group of cardiometabolic risk factors that reflect a sedentary lifestyle and the excessive intake of food among the risk factors that comprise it are located the obesity, hyperglycemia, dyslipidemia…
- Conditions
- Obesity, Diabetes, High Blood Pressure, Dyslipidemia
- Trial name
- MPATPCDNC (NCT02247635)
- Testing
- Healthy lifestyle and adherence
- Where
- Mexico
- Volunteers
- 180 people
- Sponsor
- Mexican National Institute of Public Health
Gastric Cancer
Nutrition and Lifestyle Study Cohort of Gastric Cancer in China
China has the largest gastric cancer patients population all over the world. Recent reports concluded nutrition status and lifestyle factors were associated with gastric cancer risk, however, the influence of nutrition and…
- Trial name
- NCT02216955
- Where
- China
- Volunteers
- 50,000 people
- Sponsor
- State Key Laboratory of Cancer Biology
Metabolic Syndrome
Effect of Mulberry Fruit Powder in Metabolic Syndrome
Metabolic syndrome is a raising concern globally, especially in developing countries such as Pakistan. To prevent its risk factors diet and lifestyle modification is major solution.
- Trial name
- NCT05956106
- Testing
- Black Mulberry Fruit Powder
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Metabolism and Nutrition Disorder, Obesity
Investigation of Safety and Efficacy of Once-daily Semaglutide in Obese Subjects Without Diabetes Mellitus
This trial is conducted globally. The aim of this trial is to investigate safety and efficacy of once-daily semaglutide in obese subjects without diabetes mellitus.
- Trial name
- NCT02453711
- Testing
- semaglutide, liraglutide
- Where
- 74 sites in United States, Australia and 6 more
- Volunteers
- 957 people
- Sponsor
- Novo Nordisk A/S
Obesity, Diabetes, Nutrition, Physical Health, Body Composition Changes
The Role of Nutrition in Muscle Function of Bariatric Surgery Patients
Current recommendations for protein intake after bariatric surgery are not based on strong scientific evidence. It remains unclear how much protein should be eaten to minimize muscle loss and preserve the metabolism and function…
- Conditions
- Obesity, Diabetes, Nutrition, Physical Health, Body Composition Changes, Muscle Function, Handgrip Strength Test, Protein Metabolism
- Trial name
- NCT06680492
- Where
- Canada
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Concordia University, Montreal
Cardiovascular Diseases
Risk and Prevention Study: Evaluation of the Efficacy of n-3 PUFA in Subjects at High Cardiovascular Risk
In the everyday practice cardiovascular prevention in people at high risk is still unsatisfactory and treatments with documented efficacy are generally under-used.
- Trial name
- NCT00317707
- Testing
- N-3 Polyunsaturated Fatty Acids
- Where
- Italy
- Volunteers
- 12,513 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Obese, Type 2 Diabetes
Adiponectin in Obese Women With T2DN and Effects by RAS Blocker
Insulin resistance typically characterizes type 2 diabetes (T2DM) and prediabetic states and is the prominent feature of the metabolic syndrome.Adiponectin plays an important part in glucose metabolism,insulin resistance, the…
- Conditions
- Obese, Type 2 Diabetes, Diabetic Nephropathy, Glucose Metabolism
- Trial name
- NCT00561704
- Testing
- losartan
- Volunteers
- 80 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Weight Loss, Pre Diabetes
Healthy Body Healthy Souls in the Marshallese Population
The primary aim is to pilot test a weight-loss intervention for Marshallese adults, referred to throughout as Healthy Bodies Healthy Souls (HBHS).
- Conditions
- Weight Loss, Pre Diabetes, Overweight and Obesity
- Trial name
- NCT03377244
- Testing
- HBHS, HBHS Policy, WORD DPP
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Hypertension (HTN), Diabetes (DM)
Team-Based Shared Decision-Making Program in Cardiovascular-Kidney-Metabolic Health (Healthy Heart - CKM)
The investigators are proposing a new team-based shared decision-making (SDM) program. The goal of this study is to see whether this program is practical and whether it may help adults with cardiometabolic risk factors and…
- Conditions
- Hypertension (HTN), Diabetes (DM), Hyperlipidaemia, Kidney Disease
- Trial name
- SDM in CKM (NCT07662616)
- Testing
- Team-based shared decision-making
- Volunteers
- 94 people
- Sponsor
- Johns Hopkins University
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