Clinical trials: Obesity in Men
Obese
The Effect of Mask Combined With High Flow Oxygen on Preoxygenation During Induction of General Anesthesia in Obese Patients
There is a risk of airway-related incidents during anaesthesia associated with obesity. High-flow nasal oxygen is advocated for perioperative preoxygenation in obese patients to reduce airway adverse reactions.
- Trial name
- NCT06562660
- Testing
- apnoeic
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Henan Provincial People's Hospital
Obesity
The Effect of a Short-term Very Low Calorie Diet on Heart Rate Variability in Obese Individuals
The purpose of this study is to determine whether short-term adherence to a very low calorie diet is effective in improving heart rate variability in obese individuals.
- Trial name
- NCT02070770
- Testing
- Very low calorie diet, Standard weight loss diet
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- King's College London
Obesity
A Functional Magnetic Resonance Imaging (fMRI) Study in Overweight and Obese Men (0000-103)
This study will determine whether BOLD-fMRI can be used to probe hunger and satiety states in healthy overweight or obese men and also whether fasted/fed fMRI signals can be modulated by sibutramine.
- Trial name
- NCT00914212
- Testing
- Comparator: sibutramine
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Obesity, Weight Loss
Engaging Men in Weight Loss With a Game-based mHealth and Neurotraining Program
Men in the United States have an exceptionally high prevalence of overweight and obesity, i.e., 71.3%, and 42% of men are currently attempting weight loss. However, men are dramatically underrepresented in weight loss programs.
- Trial name
- NCT05408494
- Testing
- Gamified behavioral weight loss treatment, mHealth behavioral weight loss treatment
- Where
- United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Drexel University
Normal-weight Obesity
The Interaction of Body Composition, Sex Hormones and Exercise in Men
The overall objective of this project is to advance understanding of the causes of normal weight obesity (NWO) in men, namely the hormone profile and related potential mediating mechanisms, and the efficacy of different modes of…
- Trial name
- AHA-NWO (NCT06970457)
- Testing
- Resistance Exercise Training, Aerobic Exercise Training
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University
Obesity, Physical Inactivity
"GameDay Ready": Evaluating a Behavioral Weight Management Program for Black Men Living in the Rural South
The primary objective of this study is to test the feasibility and acceptability of a 12-week behavioral weight management intervention adapted for Black men living in the rural South.
- Conditions
- Obesity, Physical Inactivity, Diet, Healthy
- Trial name
- NCT05530980
- Testing
- GameDay Ready Program
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
NAFLD
A Gender and Culturally Specific Approach to Reduce NAFLD in Mexican-American Men
Using a small Randomized Controlled Trial (RCT) study design, PNPLA3 risk allele carriers (CG/GG genotype) with NAFLD, will be assigned 2:1 to a tailored NAFLD-specific weight loss intervention compared to a wait-list control…
- Trial name
- NCT04186260
- Testing
- NAFLD-specific weight loss intervention, Wait-list control
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Obesity, Insulin Resistance
Metabolic Effects of Steroids in Obese Men
Subjects will be randomized into 4 study groups: 1. Placebo; 2. Anastrazole and Testosterone; 3. Dutasteride and Testosterone; and 4. Testosterone only.
- Trial name
- NCT00983554
- Testing
- Anastrazole, Testosterone, Dutasteride
- Where
- 2 sites in United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Healhty, Overweight or Obesity
Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of BGM1812 Injection Following Single and Multiple Subcutaneous Administration in Normal to Overweight or Obese But Otherwise Healthy Men and Women
This is a Phase 1, single-center, double-blind, placebo-controlled, dose-escalation study. The study will evaluate the pharmacokinetics (PK), pharmacodynamic (PD), preliminary efficacy, safety and tolerability of BGM1812…
- Trial name
- NCT07224399
- Testing
- BGM1812
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- BrightGene Bio-Medical Technology Co., Ltd.
Weight Loss
Exercise Duration Models, in Middle-aged Men
Duration of exercise is an important factor among the medical guides for weight loss. However, there is still little knowledge about other its models in middle-aged and older men.
- Trial name
- NCT03046641
- Testing
- Continuous training, The interval training
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- P.L.Shupik National Medical Academy of Post-Graduate Education
Obese
The Effect of Vitamin B3 on Substrate Metabolism, Insulin Sensitivity, and Body Composition in Obese Men
In animals, treatment with vitamin B3 improved insulin sensitivity and substrate metabolism. It is currently not know if vitamin B3 has the same positive effects in humans.
- Trial name
- NCT02303483
- Testing
- Nicotinamide riboside (NIAGEN TM, ChromaDex, CA, USA )
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Glucose Metabolism, Lipid Metabolism
Effects of 10-gram Collagen Protein Hydrolysate on Cardiometabolic Health
The effects of a 10g/day collagen hydrolysate for a period of 4 weeks on glycemic control and cardiovascular health in a parallel design study using overweight/ obese men and women who are likely to have a disturbed lipid and…
- Trial name
- NCT05282641
- Testing
- 10 g of collagen hydrolysate
- Where
- Netherlands
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Obesity
Clinical Study to Test the Effects of a Low-Carbohydrate Diet on Body Weight
The purpose of this study is to test the effects of a modified carbohydrate diet versus a portion controlled diet in overweight or obese men and women on body weight.
- Trial name
- NCT00351845
- Testing
- Low carbohydrate diet (behavior)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Provident Clinical Research
Obesity
Exenatide and Brown Adipose Tissue
The obesity epidemic has led to a enormous increase in the prevalence of type 2 diabetes mellitus (T2D), dyslipidemia and cardiovascular events.
- Trial name
- exe01 (NCT03002675)
- Testing
- Bydureon
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ingrid Jazet
Overweight and Obesity
UCSD Get Fit, Be Fit Study
The purpose of the Get Fit, Be Fit Study is to examine the effect of incorporating pistachios in an intensive 4-month cognitive-behavioral weight loss intervention in overweight and obese men and women, to examine effects on…
- Trial name
- NCT03387709
- Testing
- Pistachio-enriched diet, General dietary guidance diet
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Appetite and General Nutritional Disorders
Effects of Positive Energy Balance and Exercise on Appetite Hormones in Sedentary Men and Women
The purpose of this research study is to examine the effects of overfeeding and exercise on blood levels of hormones associated with regulating appetite, also thought of as feelings of hunger and satiety (fullness).
- Trial name
- NCT01354600
- Testing
- Exercise or Sedentary
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Overweight and Obesity
Mobile Phone Intervention for Physical Activity Maintenance in African American Men (MobileMen)
African American men are at risk of developing chronic disease partly due to low levels of regular physical activity. Studies have been effective in increasing physical activity levels in African American men; however for the…
- Trial name
- NCT03055416
- Testing
- Mobile Men App Prototype
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Central Obesity, Insulin Resistance
Cistanche Deserticola Extract Combined With Aerobic Exercise Improves Body Composition, Insulin Resistance and Inflammation in Men With Central Obesity
This is a randomized controlled trial to see if a combination of aerobic exercise and Cistanche deserticola extract can improve body composition, insulin resistance, and inflammation in men with central obesity.
- Conditions
- Central Obesity, Insulin Resistance, Inflammation
- Trial name
- NCT07486557
- Testing
- Supervised Aerobic Exercise, Cistanche deserticola Extract
- Where
- China
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Sarcopenic Obesity
Effect of Whole Body Electromyostimulation and/or Protein Supplementation on Sarcopenic Obesity in 70+
The aim of the study is to determine the effect of 16 weeks of Whole Body-Electromyostimulation (WB-EMS) and/or protein supplementation on Sarcopenic Obesity (SO) in community dwelling male subjects 70+ with SO .
- Trial name
- FRANSO (NCT02857660)
- Testing
- Whole body Electromyostimulation (exercise), Protein
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Healthy, Obesity
Postprandial Inflammatory Response in Healthy Men: Effect of Dietary Fat Source, Obesity and Age
The nature of dietary lipids, age and perivisceral adiposity could alter the postprandial inflammatory response. It is supposed that there is a relationship between the postprandial inflammatory response and the repartition of…
- Trial name
- NCT01066091
- Testing
- Mashed potatoes, Mashed potatoes + Oleic acid, mashed potatoes + Palmitic acid
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Yves Boirie