Clinical trials: Obesity in Men
Obesity Prevention, Diabetes Prevention
Types of Starch and Their Effect on Blood Glucose, Appetite and Food Intake
The investigators hypothesize that different types of starch vary in their effects on appetite, blood sugar and food intake. In this study, subjects consumed five soups containing 50 g of whole grain, high amylose corn, regular…
- Trial name
- NCT00980941
- Testing
- soup with or without starch
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Central Obesity, Insulin Resistance
Cistanche Deserticola Extract Combined With Aerobic Exercise Improves Body Composition, Insulin Resistance and Inflammation in Men With Central Obesity
This is a randomized controlled trial to see if a combination of aerobic exercise and Cistanche deserticola extract can improve body composition, insulin resistance, and inflammation in men with central obesity.
- Conditions
- Central Obesity, Insulin Resistance, Inflammation
- Trial name
- NCT07486557
- Testing
- Supervised Aerobic Exercise, Cistanche deserticola Extract
- Where
- China
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Obese, Weight Loss
Effects of Adding L-BAIBA or L-BAIBA + Grains of Paradise to Exercising Adult Overweight and Obese Men and Women
The goal of this intervention study is to examine changes in body composition, weight loss, and cardio-metabolic risk factors after adding supplementation of L-Beta aminoisobutyric acid (L-BAIBA) and Grains of Paradise to…
- Conditions
- Obese, Weight Loss, Body Weight, Cardiometabolic Syndrome
- Trial name
- GOP (NCT05775003)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Overweight, Obesity
Interactive Effects of an Isocaloric High-protein Diet and Resistance Exercise in Untrained Overweight Young Men
Background: The interactive effects of resistance training and dietary protein on hormonal responses in overweight or obese adults are not clear and remain controversial.
- Trial name
- NCT01714700
- Testing
- High protein diet, Resistance exercise, Standard diet, Resistance exercise
- Where
- South Korea
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Sexual Dysfunction, Endothelial Dysfunction
Effects of Lifestyle-modification Induced Weight Loss on Sexual and Urinary Function, and Quality of Life in Obese Men
This study aims to evaluate the extent to which weight loss of 5-10% from baseline, induced by exercise and diet, improves metabolic and inflammatory profile, endothelial function, erectile function, sexual desire, lower urinary…
- Conditions
- Sexual Dysfunction, Endothelial Dysfunction, Quality of Life, Inflammation
- Trial name
- NCT01554735
- Testing
- Exercise and diet
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Changi General Hospital
Inflammation, Macrophage Infiltration
Effectiveness of Sitagliptin for HIV Insulin Resistance and Inflammation
People living with human immunodeficiency virus infection (HIV) have 2-4fold greater risk for developing diabetes and heart disease than the general population.
- Conditions
- Inflammation, Macrophage Infiltration, Cardiovascular Disease
- Trial name
- NCT01552694
- Testing
- Sitagliptin
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Washington University School of Medicine
Obesity
Changes in Iron Absorption and Availability Before and After Weight Loss in Obese Pre-menopausal Women and Men.
The objective of this study is to investigate if weight loss, in particular due to adipose tissue loss, in obese patients will reverse the obesity-related reduction of iron absorption, and if this is due to a decrease in hepcidin…
- Trial name
- NCT01347905
- Testing
- Stable-isotope techniques
- Where
- Mexico
- Volunteers
- 43 people
- Sponsor
- Wageningen University
Obesity, Overweight and Obesity
Improving Quality of Life in Men and Women With Overweight or Obesity
The purpose of this study is to evaluate the effect of the Noom Healthy Weight Program, a digital behavior change weight loss intervention, on quality of life as measured both by self-report and objective measures, compared to a…
- Conditions
- Obesity, Overweight and Obesity, Quality of Life, Health Behavior
- Trial name
- NCT04871295
- Testing
- Noom Healthy Weight
- Where
- United States
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Noom Inc.
Appetitive Behavior
Effect of Exercise on Appetite, Gut Peptides and Butyrylcholinesterase Activity in Variants of the FTO Gene
Using a database of individuals with FTO genetic data, the study aims to assess the appetite, energy intake, butyrylcholinesterase, gut hormone responses to a bout of moderate- to high intensity exercise in individuals with…
- Trial name
- NCT03025347
- Testing
- Control, Exercise
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Obese Hypogonadotropic Hypogonadism
Safety and Efficacy of BGS649 in Obese, Hypogonadotropic Hypogonadal Men
This study is designed as a 2-part study, with Part 1 being open-label to best determine the appropriate dose levels to use in Part 2, which has a randomized, double-blind, placebo controlled design.
- Trial name
- OHH (NCT01200862)
- Testing
- Investigational new drug company code: BGS649
- Where
- 5 sites in United States, Canada
- Volunteers
- 29 people
- Sponsor
- Mereo BioPharma
Metabolic Syndrome
Metabolic Syndrome Cohort in Korea
Patients with metabolic syndrome living in Seoul area are included in this prospective registry for more than 10 years. All enrolled patients undergo thorough medical history survey.
- Trial name
- NCT02077530
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Type 2 Diabetes, Hypertension
Health Effects of Recreational Soccer in Type 2 Diabetic Men
The present study investigates the effects of recreational soccer in type 2 diabetic men in regard to muscular, cardiovascular adaptations and glycaemic control.
- Conditions
- Type 2 Diabetes, Hypertension, Obesity, Metabolic Syndrome
- Trial name
- NCT01636349
- Testing
- soccer exercise or continued daily lifestyle
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- University of Copenhagen
Obstructive Sleep Apnea (OSA)
Metabolic Study of Sleep Apnea in Men and Women
The purpose of this study is to look at the metabolic (use of energy) and hormonal features of sleep problems in men and women.
- Trial name
- NCT00706511
- Testing
- CPAP
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Chicago
Erythema, Inflammation
Effects of Phytonutrients on Vascular Health and Skin in Obese Males
This study will determine the effects of beneficial compounds of plant foods, such as pomegranate on cardiovascular health, skin inflammation and aging.
- Trial name
- PomSkin (NCT03496584)
- Testing
- Pomegranate Juice
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Pre-diabetes, Overweight and Obesity
Timing Exercise Training as Strategy to Improve Insulin Sensitivity and Substrate Metabolism in Men and Woman With Pre-diabetes
n a retrospective analysis of an exercise training program performed either in the morning or afternoon, we found that the afternoon training group improved their peripheral insulin sensitivity and fasting plasma glucose levels…
- Trial name
- Timed Training (NCT06014684)
- Testing
- Timing of exercise
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Eating, Obesity
(Mis)Perceptions About Healthy Eating: Effects on Food Intake and Appetite in Men and Women
In the face of an increased prevalence of obesity and chronic diseases in Canada, much effort has been invested to educate the population about healthy eating.
- Trial name
- COLLATION (NCT01141140)
- Testing
- Healthy, Diet, Unhealthy
- Where
- Canada
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Laval University
Overweight and Obesity, Weight Loss
The Effects of a Commercially Available Weight Loss Program on Body Weight in Overweight Men and Women
The primary purpose of this study (Part A) is to assess changes in body weight and body circumference parameters that are achievable after 4 weeks on the Nutrisystem program compared to a self-directed diet (i.e.
- Trial name
- NCT03070015
- Testing
- Nutrisystem, Self-Directed DASH
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Nutrisystem, Inc.
Obesity
Hydrogen-rich Water and Appetite in Obesity
The main goal of this study is to investigate how dihydrogen supplementation impacts body composition, appetite, quality of life specific to obesity, and levels of the hormone GLP-1 in men and women with obesity.
- Trial name
- HYDRAPPET (NCT06722326)
- Testing
- Dietary Supplement: Hydrogen-rich water, Dietary Supplement: Control water
- Where
- Serbia
- Volunteers
- 36 people
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Nitric Oxide, Vascular Function
Nutritional Supplements and Nitric Oxide Bioactivity
Obese people have a disturbed postprandial metabolism and thereby a decreased postprandial vascular function. Nitric oxide plays an important role in the postprandial vascular function.
- Conditions
- Nitric Oxide, Vascular Function, L-Arginine, Nitrate / Nitrite
- Trial name
- NCT03625596
- Testing
- L-Arginine, Nitrate / Nitrite
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Healthy
A Study to Test How Well Different Doses of BI 3034701 Are Tolerated by Healthy Men and People With Overweight or Obesity
This study is open to healthy people and people with overweight or obesity. It has 2 parts. Part A is open to healthy men between 18 and 55 years of age.
- Trial name
- NCT06352437
- Testing
- BI 3034701
- Where
- Germany
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim