Clinical trials: Observation
RED S, Eating Disorders
Relative Energy Deficiency in Sports (REDs) in Swedish Athletes
Background: Relative Energy Deficiency in Sport (REDs) describes impairment of health and performance due to problematic (long-term/severe) low energy availability (LEA), with or without eating disorders.
- Trial name
- REDs-Sweden (NCT06371963)
- Where
- Sweden
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Linnaeus University
Gestational Diabetes, Hypoglycemia, Neonatal
Glucose Control During Labour in Gestational Diabetes Mellitus With Insulin Treatment: A Randomized Controlled Trial
Pregnant women with gestational diabetes who are treated with insulin and their daily insulin dose is 30 IU or more will be randomized into two groups. Active treatment group will receive insulin-glucose-infusion during labour.
- Trial name
- NCT02590016
- Testing
- Insulin, Aspart
- Where
- Finland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Hernia
Large Abdominal Hernia Repair With SurgiMend 3.0
The rate of hernia recurrence at one year following repair of a large abdominal hernia with a biologic mesh is high, ranging from 30% to 100%, with a reported historic average rate of 40%.
- Trial name
- BRIDGE (NCT00892333)
- Where
- 8 sites in United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Integra LifeSciences Corporation
Breast Cancer, Lung Cancer
Study for the Multidimensional Analyses of Resistance and Toxicity to Immune- and Targeted-therapies.
Novel treatment modalities like targeted therapies and Immune checkpoint inhibitors have revolutionised the therapeutic landscape in oncology and hematology, significantly improving outcomes even in clinical contexts in which…
- Conditions
- Breast Cancer, Lung Cancer, Melanoma, Head and Neck Cancer
- Trial name
- POSITive (NCT06321640)
- Testing
- Cohort A: primarily operable disease, candidate to adjuvant, Cohort B: locally advanced disease, Cohort C: metastatic disease
- Where
- Italy
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- European Institute of Oncology
Cesarean Section
Ondansetron Prior Spinal Anaesthesia
Since Ondansetron is commonly used during cesarean deliveries to treat nausea and vomiting, this study will observe the correlation between ondansetron administration and effect on hemodynamics in order to confirm that the use of…
- Trial name
- Ondansetron (NCT06431568)
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postmenopausal Osteoporosis
Resolution of Effect of Bisphosphonates on Bone in Postmenopausal Osteoporosis
This is a 2year observational study that will recruit patients who have previously completed a randomised, open label, parallel, single centre study (TRIO Study) of three bisphosphonates: alendronate, ibandronate and risedronate.
- Trial name
- NCT01406613
- Testing
- Observation
- Where
- United Kingdom
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
COVID-19
A COVID-19 Symptom, Exposure and Immune Response Registry
This is a 6-month, 100% remote study that will collect a broad range of data that may provide insight into the COVID-19 global pandemic.
- Trial name
- NCT04348942
- Where
- United States
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- ObvioHealth
Cervical Cancer, Condylomata Acuminata
Plateau Antibody Levels of a Recombinant (E.Coli) HPV Nonavalent Vaccine Versus Gardasil®9 in Young Women
This study is designed to compare plateau antibody levels of a novel recombinant human papillomavirus vaccine (types 6,11,16,18,31,33,45,52,58 )(E.Coli) manufactured by Xiamen Innovax Biotech CO., Ltd., with Gardasil®9 in females…
- Trial name
- NCT06197802
- Testing
- Recombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58 )Vaccine(E.Coli), Gardasil®9
- Where
- China
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- Xiamen University
Caudal Epidural Anesthesia, Sacral Erector Spinae Plane Block
Comparison of Erector Spinae Plane Block and Caudal Block for Postoperative Analgesia in Pediatric Patients Undergoing Orchiopexy: A Prospective Observational Study
This study aims to compare the analgesic efficacy of ultrasound-guided erector spinae plane block and caudal block for postoperative pain management in pediatric patients undergoing orchiopexy.
- Conditions
- Caudal Epidural Anesthesia, Sacral Erector Spinae Plane Block, Orchiopexy, FLACC Scale
- Trial name
- NCT07762339
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Obesity, Childhood
Evaluation of the Impact of Eating Habits on Children's Corpulence
Childhood obesity has been rising steadily over the past 40 years. In 2016, the World Health Organization (WHO) observed around 340 million overweight or obese children and adolescents worldwide, including one in five in France.
- Trial name
- KALI SANTE (NCT06128083)
- Where
- France
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Extrahepatic Cholangiocarcinoma
An Observational Real World Study on the Efficacy and Safety of Toripalimab Injection Combined With TACE in the Treatment of Extrahepatic Cholangiocarcinoma
This is an open-label, single-arm, multicenter phase II clinical study to preliminarily observe and evaluate the efficacy and safety of Toripalimab combined with TACE in the treatment of extrahepatic cholangiocarcinoma.
- Trial name
- NCT05448183
- Testing
- Toripalimab, Gemcitabine,Oxaliplatin
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Xuhua Duan
Oral Surgical Procedures
Retrospective Observational Study of Implant-supported Restorations With Dental Implants.
This retrospective study aims to value the bone loss and the success and survival of the dental implants produced by additive manufacturing installed in an area grafted with Plenum® Osshp (synthetic bone graft).
- Trial name
- NCT06154057
- Testing
- Dental Implants installed in an grafted area (sinus lifting), Dental Implants installed in an grafted area (ridge augmentation), Dental Implants installed in an grafted area (extraction sites)
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- M3 Health
Health Behavior, Diet, Healthy
Continuous Observations of Behavioural Risk Factors in Asia (COBRA)
The aim of this study is to advance understanding of behavioural risk factors for cardiovascular disease and type 2 diabetes in Singapore.
- Conditions
- Health Behavior, Diet, Healthy, Physical Activity, Sedentary Behavior
- Trial name
- COBRA (NCT05136872)
- Where
- Singapore
- Volunteers
- 1,361 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Respiratory Function, Motor Imagery
Motor Imagery and Action Observation in Respiratory Training
The principal aim of this study was to asses the effects of motor imagery and action observation training on ventilatory and functional capacity through a randomized controlled trial.
- Conditions
- Respiratory Function, Motor Imagery, Action Observation Training
- Trial name
- NCT05662072
- Testing
- Motor imagery, Action observation
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Pulpitis - Irreversible, Pulpitis - Reversible
Observational Cross-sectional Study Aiming to Determine the Correlation Between Pulpal Status and IL-8 and Presepsin Levels in the Pulpal Blood.
Observational cross-sectional study aims to determine the correlation between pulpal status and IL-8 and Presepsin levels in the pulpal blood.
- Trial name
- Cross-section (NCT07466095)
- Testing
- IL-8 and Presepsin levels in the pulpal blood.
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hepatitis D, Chronic
An Observational Study on the Prevalence of Chronic Hepatitis D in Romania and the Efficacy of Treatment With Pegasys (Peginterferon Alfa-2a)
This prospective, multicenter, observational study will assess the prevalence of chronic hepatitis D in patients with chronic hepatitis B in Romania and evaluate the efficacy of Pegasys (peginterferon alfa-2a) in patients with…
- Trial name
- NCT01861444
- Where
- Romania
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Metabolic Dysfunction-associated Fatty Liver Disease, Metabolic Disease
NMR-based Metabolic Profiling Identifies High Risk of MAFLD Patients With Advanced Fibrosis
This study aim to find out metabolic molecules in blood and urine which could identify high risk of advanced fibrosis in MAFLD patients via NMR-based metabolic profiling.
- Trial name
- NCT05734599
- Testing
- NMR-based metabolic profiling
- Where
- China
- Volunteers
- 1,194 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Acute Uncomplicated Diverticulitis
Acute Uncomplicated Diverticulitis and Conservative Treatment: Accuracy of Inflammatory Indexes for Failure Prediction: Observational Prospective Cohort Study. (AUDRIP Trial)
This is an observational multicenter study that will analyse the accuracy of inflammatory indexes as neutrophil-lymphocyte ratio and platelet-lymphocyte ratio, to predict the failure of conservative treatment of patients…
- Trial name
- AUDRIP (NCT05833698)
- Testing
- Elevation of NLR
- Where
- Spain
- Volunteers
- 2,160 people, healthy volunteers welcome
- Sponsor
- Fundación de Investigación Biomédica - Hospital Universitario de La Princesa
Alzheimer's Disease, Mild Cognitive Impairment
Wake Forest Alzheimer's Disease Clinical Core
Efforts to find treatments for AD have yielded only modest benefits, likely because longstanding AD pathological processes induce irreversible neurological compromise.
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Prediabetic State
- Trial name
- ADCC (NCT03140865)
- Where
- United States
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Hepatitis C
The National Australian HCV Point-of-Care Testing Program - HCV Antibody Testing Minimal Dataset
The goal of this observational study is to learn if offering a point-of-care screening test for exposure to the Hepatitis C virus, before providing a diagnostic test for Hepatitis C infection can increase testing, diagnosis and…
- Trial name
- NCT05713136
- Testing
- Diagnostic Test: Point-of-Care Testing
- Where
- 13 sites in Australia
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Kirby Institute
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