Clinical trials: Observation
Chronic Liver Disease
An Observational Study Evaluating Patients With Chronic Liver Diseases Associated With Hepatic Steatosis
Hepatic steatosis may cause inflammation and fibrosis within the liver potentially leading to end-stage liver disease cirrhosis, liver failure and death.
- Trial name
- FALL (NCT05335603)
- Where
- Denmark
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Hyperlipidemia
Observation on the Correlation Between Serum/Fecal Isoflavones, Abundance of TMA-producing Bacteria and Serum TMAO in Hyperlipidemia and Healthy Subjects
Previous studies have shown that trimethylamine N-oxide (TMAO), a gut microbiota-related metabolite, plays a significant role in the development and progression of cardiovascular disease (CVD).
- Trial name
- NCT06890780
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Healthy Adults
Immune Fitness Prediction
The overall objective of the study is to determine whether self-rated, perceived immune fitness (using questionnaire) is associated with biological assessment of immune fitness (immune signatures in the blood).
- Trial name
- NCT05078346
- Where
- Switzerland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Supracondylar Fracture, Morbidity
Comparison of Day-time and Night-time Operations of Supracondylar Humeral Fractures
This study aims to investigate that performing supracondylar humerus fracture operations during daylight hours may have better results than performing them at night.
- Trial name
- NCT04694469
- Testing
- Closed reduction and percutaneous pinning (CRPP)
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Tetanus
A Study of Tetanus Antibody of Healthy Adults
The goal of this observational study is to learn about antibody level of tetanus of adults in high-income city of china. The main question it aims to answer is: 1.
- Trial name
- tetanus (NCT07724379)
- Where
- China
- Volunteers
- 2,009 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Gastric Cancer
Gastric Cancer Early Detection by Multi-dimensional Analysis of cfDNA
To facilitate the early gastric cancer diagnosis, an assay based on assessing large-scale methylation and fragmentation profiles of the plasma cell free (cfDNA) will be developed and validated.
- Trial name
- NCT05668910
- Testing
- whole genomic methylation and fragmentation profile analysis of cfDNA
- Where
- China
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- GeneCast Biotechnology Co., Ltd.
Hypoglycemia
Evaluation of Hypo-Safe Hypoglycaemia Alarm Device - a Pilot Study
The trial aims at measuring the safety and performance of the Hyposafe device.
- Trial name
- Pilot (NCT01238016)
- Testing
- experimental
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- UNEEG Medical A/S
Human Papillomavirus Infection
Observational Surveillance Study to Detect Potential Safety Signals in Patients Who Have Had at Least One Dose of GARDASIL™ (V501-031)
This is a post-licensure safety surveillance program to detect potential safety signals in subjects, from the managed care organizations database, who have used GARDASIL™.
- Trial name
- NCT01078220
- Volunteers
- 189,629 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Oral Lichen Planus
Oral Lichen Planus and Systemical Oncological Comorbidities
Lichen planus (LP) is a chronic mucocutaneous inflammatory disease of unknown etiology. In its oral variant, oral lichen planus (OLP) has a reported prevalence ranging from 0.5% to 2.2% in the general population.
- Trial name
- NCT06449248
- Testing
- Checking of appropriateness of OLP diagnosis
- Where
- Italy
- Volunteers
- 1,517 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Gingivitis and Periodontal Diseases, Periodontitis
Association Between Periodontal Status and the Prevalence of Entamoeba Gingivalis and Trichomonas Tenax
This prospective observational study aims to investigate the prevalence and clinical significance of two oral protozoa, Entamoeba gingivalis and Trichomonas tenax, among patients attending the Bolu Abant İzzet Baysal University…
- Trial name
- NCT07551115
- Testing
- Clinical Periodontal Evaluation, Microscopic Examination of Oral Protozoa
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
COVID-19 Vaccines
Variables Influencing Anti-COVID-19 Vaccinations Around the World: an Analysis Conducted on Aggregated Data Sourced From Institutional Databases to Understand Whether and How Different Variables Could Affect the Vaccine Coverage (WORLDCOV: Worldwide Determinants of COVID-19 Vaccination)
Vaccination coverage against COVID-19 differs widely between countries: in order to address this public health issue, this observational study seeks to understand whether there are any determinants/predictors.
- Trial name
- WORLDCOV (NCT05471635)
- Testing
- COVID-19 Vaccine
- Where
- Italy
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Alberto Peano
Crises Situations That the Patients and Caregivers Confront in Daily Practice
Definition of Crises in Medical Oncology: a Two-way Perspective of Patients and Caregivers. The COPE Study. (COPE)
Our objective is to identify the main crises facing the patients and caregivers in medical oncology and rank them by order of importance.
- Trial name
- COPE (NCT04736940)
- Where
- France
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hyperphosphatemia
Multicenter, Open, Prospective, 48 Weeks, Observational Study ,Evaluate the Safety and Efficacy of Nephoxil Capsule
The purpose of this study is to evaluate the safety and efficacy of Nephoxil capsule administration for the improvement of hyperphosphatemia in CKD patients undergoing hemodialysis under actual conditions of routine medical care.
- Trial name
- NCT06206135
- Testing
- the low-dose group (1.5 g/day) or the standard-dose group (4 g/day)
- Where
- South Korea
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- LG Chem
Pseudoxanthoma Elasticum, Tomography, Optical Coherence
CHOPXE - Analysis of Choriocapillaris Flow Deficits in Patients With Pseudoxanthoma Elasticum
This observational study sets out to compare choriocapillaris flow deficits between healthy control subjects and patients with pseudoxanthoma elasticum.
- Conditions
- Pseudoxanthoma Elasticum, Tomography, Optical Coherence, Retinal Disease
- Trial name
- CHOPXE (NCT07006649)
- Testing
- Opthtalmologic diagnosis tests
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Obesity and Cardiovascular Risk
Lifestyle Program Focused on Nourishment, Well-Being, and Health Behaviors in Women With Obesity
Women, Weight and Well-Being is a 12-month research study looking at how a supportive lifestyle program may help women whose weight increases their risk for heart disease.
- Trial name
- NCT07404150
- Testing
- lifestyle change program
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Heather Conradson
Intensive Care Medicine, ARDS
Change of Immune Cell of ARDS Patients：an Observational Study
To evaluate change of different immune cellsduring ARDS and its impact on prognosis.
- Trial name
- NCT02958748
- Testing
- taking blood sample
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Southeast University, China
Agitation
Naturalistic Adasuve Clinical Trial Study
There is limited information on the best psychoactive medication to treat agitated patients in the emergency department. The intent of this study is to fill in knowledge gaps in the current practice of treating psychiatric…
- Trial name
- NCT02877108
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mt Sinai Hospital, Chicago
Anesthesia, Traumatic Brain Injury
The Effect of Mannitol Volume With Changes in Osmolarity in Traumatic Brain Injury
This observational study is designed to research the effect of mannitol volume administration with changes in osmolarity in patients with traumatic brain injury to guide the safe use of mannitol in these patients.
- Trial name
- NCT06846307
- Testing
- Mannitol
- Where
- Indonesia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universitas Diponegoro
Family Satisfaction
The Reliability And Validity Of Family Satisfaction In Intensive Care Unit 24 (FS-ICU 24) Scale In Turkish Language
Purpose of this study was to investigate the validity and reliability of Family Satisfaction in the Intensive Care Unit-24 (FC-ICU 24) survey in Turkish language, evaluation the satisfaction of intensive care unit patients'…
- Trial name
- NCT03733977
- Where
- Turkey (Türkiye)
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Knee Osteoarthritis, Knee Pain Chronic
Cognition, Pain and Wellbeing
Osteoarthritis (OA) is the most common form of arthritis and for 4 in 10 people pain from OA is not adequately controlled. The pain experience of people suffering from chronic pain largely depends on their individual perception…
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Arthritis
- Trial name
- CPW (NCT04620525)
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
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