Clinical trials: Observation
Central Sensitisation, Low Back Pain
Nociplastic Pain Symptoms and Sensory Profiles in Low Back Pain
Assessing associations between Sensory profiles and nociplastic pain symptoms, and assessing the prognostic value of sensory profiles in the development of nociplastic pain symptoms in a low back pain population.
- Trial name
- NCT05592405
- Where
- Netherlands
- Volunteers
- 103 people
- Sponsor
- Vrije Universiteit Brussel
Degenerative Joint Disease
Journey II BCS EU Observational Trial
Post-market study to confirm the safety and efficacy of the Journey II BCS knee prosthesis.
- Trial name
- NCT02211794
- Testing
- data collection
- Where
- 5 sites in Belgium, Italy and 3 more
- Volunteers
- 179 people
- Sponsor
- Smith & Nephew Orthopaedics AG
Arterial Hypertension, Sodium Urine
TO ASSESS THE EFFECTIVENESS OF THE INTERVENTION OF THE LOW-SODIUM DIET IN PATIENTS WITH HTA
Arterial hypertension is an independent vascular risk factor and a frequent reason for consultation in Primary Care. It generates high cardiovascular morbidity and mortality (stroke, heart disease, kidney failure and other…
- Conditions
- Arterial Hypertension, Sodium Urine, Primary Care Center, Diet Habit
- Trial name
- IDI-HTA2020 (NCT04677322)
- Testing
- Adult patients diagnosed and treated for high blood pressure
- Where
- Spain
- Volunteers
- 2 people
- Sponsor
- Instituto de Investigación Marqués de Valdecilla
Heart Failure, Iron Deficiencies
IRONHEART: Intravenous Iron in Non-ischaemic Heart Failure
The aim of this study is to observe the effect of intravenous ferric derisomaltose in participants with non-ischaemic heart failure (LVEF<40%), iron deficiency (TSATS<20%) and established on heart failure therapy including…
- Trial name
- IRONHEART (NCT06542822)
- Testing
- Ferric derisomaltose
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Breast Cancer Female
Immediate Breast Reconstruction Following Mastectomy (IRMA)
Based on data from the US Surveillance, Epidemiology and End Result Program (SEER), the rates of nipple-sparing mastectomy (NSM) have risen 202% since 2009.
- Trial name
- IRMA (NCT04390529)
- Testing
- quality-of-life questionnaire: BREAST-Q
- Where
- 15 sites in Switzerland
- Volunteers
- 515 people
- Sponsor
- Thurgau Breast Center
Early Stage Breast Carcinoma
EXamining PErsonalised Radiation Therapy for Low-risk Early Breast Cancer
This is a randomised, phase III, non-inferiority trial evaluating radiation therapy versus observation following breast conserving surgery and planned endocrine therapy in patients with stage I breast cancer of luminal A subtype…
- Trial name
- EXPERT (NCT02889874)
- Testing
- Omission of radiation therapy
- Where
- 68 sites in Argentina, Australia and 7 more
- Volunteers
- 1,167 people
- Sponsor
- Breast Cancer Trials, Australia and New Zealand
Invasive Breast Cancer Between 2002 and 2005
Retrospective Observational Study About Evolution of Patients With Breast Cancer in Hospitals From GEICAM Group
This study is a non-interventional (NIS), multicenter, retrospective cohort study, which will obtain data from patients diagnosed with invasive breast cancer between 2002 and 2005 in the medical oncology departments of hospitals…
- Trial name
- ALAMO-IV (NCT03210974)
- Where
- 41 sites in Spain
- Volunteers
- 13,135 people
- Sponsor
- Spanish Breast Cancer Research Group
Non-Small Cell Lung Cancer
Observations From Long Term Responders in the Gefitinib (Iressa) Expanded Access Program (EAP)
The purpose of the study is to determine patient characteristics from patients that have used Iressa for a period of minimal 3 years.
- Trial name
- NCT01103089
- Where
- 11 sites in Netherlands
- Volunteers
- 10 people
- Sponsor
- AstraZeneca
Pain, Postoperative
pMDT in Thoracic Surgery--The Process Implementation Stage
The risk of acute and chronic pain after thoracic surgery is high. The multi-disciplinary postoperative pain management strategy is the best way to control postoperative pain in thoracic surgery.
- Trial name
- NCT03761550
- Testing
- pMDT(Process Implementation)
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Peking University People's Hospital
Musculoskeletal Diseases
Study on Musculoskeletal Disorders in Spanish Pianist
Background: musculoskeletal disorders related to instrumental practice (TMRPI) affect many pianists. Objectives: to know the prevalence of TMRPI in the population of Spanish pianists and its relationship with gender, age…
- Trial name
- NCT04599413
- Testing
- SURVEY
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Católica de Ávila
Advanced Hepatocellular Carcinoma
Efficacy and Safety of SBRT Combined With Atezolizumab Plus Bevacizumab vs Atezolizumab Plus Bevacizumab in Treating Unresectable Advance Hepatocellular Carcinoma.
SBRT, atezolizumab, and bevacizumab have different mechanisms of action and can potentially have synergistic effects when combined.
- Trial name
- NCT06244446
- Testing
- No intervention
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Out-of-Hospital Cardiac Arrest, Pulmonary Ventilation
CAvent-Ventilation During Advanced Cardiopulmonary Resuscitation in Out-of-hospital Cardiac Arrest- an Observational Study
The aim of this observational study is to investigate how ventilations is given during cardiopulmonary resuscitation (CPR) given by advanced life support providers (ALS).
- Trial name
- CAvent (NCT04237727)
- Testing
- Fluxmed GrH portable pneumotachograph
- Where
- 5 sites in Netherlands, Sweden
- Volunteers
- 241 people
- Sponsor
- Uppsala University
Lafora Disease
Natural History and Functional Status Study of Patients With Lafora Disease
A natural history and functional status study to characterize the clinical disease course in Lafora disease patients using standardized, quantitative evaluations and to identify useful biomarkers and clinical outcome measures for…
- Trial name
- NCT03876522
- Where
- 4 sites in United States, Italy and 1 more
- Volunteers
- 33 people
- Sponsor
- Ionis Pharmaceuticals, Inc.
Carotid Artery Aneurysm
Carotid Artery Aneurysm Treatment Using CGuard Divert-And-Heal Strategy
Non-randomized, single arm, open label, academic observational study of CGuard MicroNet covered stent system use to achieve endovascular lumen reconstruction in carotid artery aneurysms with indications for treatment (enlarging…
- Trial name
- C-HEAL (NCT04434456)
- Testing
- CGuard stent implantation
- Where
- Poland
- Volunteers
- 25 people
- Sponsor
- John Paul II Hospital, Krakow
Parkinson Disease
Real-World Patient Experiences Using Continuous Subcutaneous Apomorphine Infusion (ONAPGOTM) in the United States:
Real-World Participants Experiences Using Continuous Subcutaneous Apomorphine Infusion (ONAPGOTM) in the United States: A Prospective, Phase 4, Multicenter, Observational Study in Parkinson's Disease
- Trial name
- NCT07219927
- Testing
- Observational study
- Where
- 5 sites in United States
- Volunteers
- 120 people
- Sponsor
- Supernus Pharmaceuticals, Inc.
Hepatitis C
Use-Results Surveillance Study of Sovaldi® Plus Rebetol® in Japanese Patients With Chronic Genotype 2 Hepatitis C Virus Infection
This use-results post-marketing surveillance (PMS) study for Sovaldi® tablets (sofosbuvir, SOF) administered in combination with Rebetol® capsules (ribavirin, REB) will evaluate the safety and efficacy of SOF administered in…
- Trial name
- NCT02562742
- Testing
- SOF, REB
- Where
- 45 sites in Japan
- Volunteers
- 554 people
- Sponsor
- Gilead Sciences
COVID, ARDS
Intensive Care Therapy of Covid-19 Disease in Germany
Multi-center retrospective and prospective observational study of Covid-19 patients with severe or critical illness treated on a German ICU
- Trial name
- NCT04455451
- Where
- 27 sites in Germany
- Volunteers
- 2,054 people
- Sponsor
- University Hospital Tuebingen
Diabetes, Diabetes Mellitus, Type 2
Efficacy of Biphasic Insulin Aspart 30 in Type 2 Diabetics Failing on OADs
This trial is conducted in the United States of America (USA). The aim of this trial is to investigate the effectiveness of biphasic insulin aspart 30 in type 2 diabetics not achieving blood sugar levels when treated with oral…
- Trial name
- NCT00791895
- Testing
- biphasic insulin aspart 30
- Where
- 15 sites in United States
- Volunteers
- 102 people
- Sponsor
- Novo Nordisk A/S
Chronic Stroke
Action Observation Therapy in Chronic Stroke Via Telerehabilitation
Stroke, a leading cause of disability worldwide, particularly affects upper extremity function, rendering individuals dependent on others for daily living activities and reducing their quality of life.
- Trial name
- NCT07631182
- Testing
- Conventional physiotherapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Karabuk University
Nulliparous
Scandinavian Mirena Insertion Nulliparous Trial.
In this non-interventional study we investigate the nulliparous women individual evaluation of the insertion procedure of LNG-IUD and the follow-up period of 3 months post insertion.
- Trial name
- NCT00798980
- Testing
- Mirena (BAY86-5028)
- Where
- Sweden
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Bayer
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