Clinical trials: Observation
Eustachian Tube Dysfunction
Eustachian Tube Dysfunction Assessment
The purpose of the study is to understand the exact mechanism of the activity of paratubal muscles in opening eustachian tube in patients with the functional eustachian tube and those with the eustachian tube dysfunction problem.
- Trial name
- ETDA (NCT02667301)
- Testing
- EMG recording, Tympanic Cavity Air Exchange Test, Tympanometer test
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Stratejik Yenilikci Girisimler Ltd.
Hidradenitis Suppurativa
Post Marketing Observational Study (PMOS) to Assess Quality of Life in Swedish Hidradenitis Suppurativa (HS) Patients
The objective of this study is to assess quality of life (QoL), skin pain, work productivity/activity and health related problems in Swedish patients with moderate to severe HS before and after 6 months treatment with Adalimumab.
- Trial name
- HOPE (NCT02739828)
- Testing
- Adalimumab
- Where
- 11 sites in Sweden
- Volunteers
- 24 people
- Sponsor
- AbbVie
Psoriasis
Study Evaluating the Safety and Effectiveness of Etanercept for the Treatment of Pediatric Psoriasis
Psoriasis is a chronic, often severe, autoimmune condition that affects approximately 2% of the world's population. The epidemiology of pediatric psoriasis has not been well documented and no treatment guidelines exist for…
- Trial name
- PURPOSE (NCT01100034)
- Testing
- Etanercept
- Where
- 29 sites in France, Germany and 6 more
- Volunteers
- 72 people
- Sponsor
- Pfizer
Cystic Fibrosis (CF)
: TRANSITION: An Observational Study of Transition From Lumacaftor/Ivacaftor to Tezacaftor/Ivacaftor (Tez/Iva)
This study is a single center study of clinical and laboratory outcomes in patients ≥ 12 who transition from use of Orkambi to tez/iva.
- Trial name
- NCT03445793
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Jewish Health
Anesthesia, Caudal
A Prospective Observational Study of Epidural Pressures During Caudal Epidural in the Pediatric Population
This study is a prospective study of epidural pressure changes when local anesthetic is injected from the caudal route. All patients will receive the same weight based volume dose of local anesthetic after induction of general…
- Trial name
- NCT02233309
- Testing
- Monitoring of pressures during caudal anesthesia
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Jessica Goeller
Hypertension
J-TARGET,Japanese Telmisartan Study for Antihypertensive Good Effect in Long Term Observation
The primary objective of this post marketing survey is to prospectively investigate patients with hypertension treated with Micardis Tablets (hereinafter "this drug") in routine clinical settings for 3 years in order to determine…
- Trial name
- NCT00659581
- Testing
- Telmisartan
- Volunteers
- 21,471 people
- Sponsor
- Boehringer Ingelheim
Lung Diseases, Interstitial
INREAL - Nintedanib for Changes in Dyspnea and Cough in Patients Suffering From Chronic Fibrosing Interstitial Lung Disease (ILD) With a Progressive Phenotype in Everyday Clinical Practice: a Real-world Evaluation
The primary objective of this observational study is to investigate the correlation between changes from baseline at 52 weeks in forced vital capacity (FVC) and changes from baseline at 52 weeks in dyspnea score points or cough…
- Trial name
- INREAL (NCT04702893)
- Testing
- Nintedanib
- Where
- 21 sites in Germany
- Volunteers
- 108 people
- Sponsor
- Boehringer Ingelheim
Stargardt Disease
A Natural History of the Progression of Stargardt Disease: Retrospective and Prospective Studies
Stargardt disease is currently an incurable and untreatable macular dystrophy that causes severe visual loss in children and young adults, thereby causing enormous morbidity with economic, psychological, emotional, and social…
- Trial name
- ProgSTAR (NCT01977846)
- Where
- 9 sites in United States, France and 2 more
- Volunteers
- 259 people
- Sponsor
- Foundation Fighting Blindness
Hemorrhage, Bleeding Hemorrhage
EmboCube Gelatin Embolization to Control Bleeding or Hemorrhaging
This is a multicenter, observational study of the use of EmboCube Embolization Gelatin to control hemorrhaging and bleeding. The study is designed to enable the collection, analysis, and reporting of data from "real-world" use of…
- Trial name
- NCT05307783
- Testing
- EmboCube Embolization Gelatin
- Where
- 5 sites in Australia, France
- Volunteers
- 101 people
- Sponsor
- Merit Medical Systems, Inc.
Prostate Cancer
Optimizing Active Surveillance in Low-Risk Prostate Cancer: a Pilot Study
This is a pilot evaluation of a patient-centered intervention that enables providers to support men on active surveillance to maximize adherence.
- Trial name
- NCT05764005
- Testing
- web-based tool (MAP- Management of Active surveillance in Prostate Cancer), MUSIC website
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Michigan Rogel Cancer Center
Transthyretin Gene Mutations, Transthyretin Amyloidosis
Transthyretin Amyloidosis Outcome Survey (THAOS)
THAOS is a global, multi-center, longitudinal observational survey open to all patients with transthyretin amyloidosis (ATTR), including ATTR-PN (polyneuropathy), ATTR-CM (cardiomyopathy) and wild-type ATTR-CM.
- Trial name
- THAOS (NCT00628745)
- Testing
- None. Observational Study.
- Where
- 113 sites in United States, Argentina and 23 more
- Volunteers
- 6,718 people
- Sponsor
- Pfizer
Kidney Disease, Chronic
An Observational Study of Mircera (Methoxy Polyethylene Glycol-epoetin Beta) in Patients With Chronic Kidney Disease Not On Dialysis
This observational, prospective, multicenter study will describe the mean dose of Mircera (methoxy polyethylene glycol-epoetin beta) and the hemoglobin levels in patients with chronic kidney disease.
- Trial name
- NCT01318512
- Where
- Czechia
- Volunteers
- 340 people
- Sponsor
- Hoffmann-La Roche
Rheumatoid Arthritis
An Observational Study to Describe in Routine Clinical Practice the Treatment Patterns of Usage of Biological DMARDs in RA Patients.
This observational study will describe the treatment patterns of usage of biological DMARDs in routine clinical practice and the demographics and RA disease characteristics in patients suffering from rheumatoid arthritis.
- Trial name
- NCT02590562
- Testing
- Routine clinical practice
- Where
- 15 sites in China
- Volunteers
- 808 people
- Sponsor
- Hoffmann-La Roche
Osteoarthritis, Pain
Evaluation of the Effectiveness, Compliance of Ibuprofen in a Sustained Release Form in the Treatment of Egyptian Osteoarthritic Patients
This is a prospective, multi-center, post-marketing observational study to evaluate the effectiveness and compliance of ibuprofen in a sustained release form in the treatment of Egyptian osteoarthritic patients.
- Conditions
- Osteoarthritis, Pain, Morning Stiffness
- Trial name
- NCT01226095
- Where
- 15 sites in Egypt
- Volunteers
- 519 people
- Sponsor
- Abbott
HTLV I Associated Myelopathy
Ciclosporin in HTLV-1 Associated Myelopathy/ Tropical Spastic Paraparesis (HAM/TSP)
HAM/TSP is a chronic disease of the spinal cord, caused by a virus called HTLV-I. Worldwide approximately 20 million persons are infected.Infection with HTLV-I is lifelong, and about 3% of infected persons will develop this…
- Trial name
- HAM05 (NCT00773292)
- Testing
- ciclosporin
- Where
- United Kingdom
- Volunteers
- 7 people
- Sponsor
- Imperial College London
Venous Leg Ulcer
Effect of VarIthena on Wound Healing in Venous Leg Ulcers (VLU)
A 12 month, multicenter, open-label registry to observe chronic venous insufficiency resulting in VLU treated with Varithena.
- Trial name
- VIEW-VLU (NCT03257254)
- Testing
- Varithena
- Where
- 14 sites in United States, Canada
- Volunteers
- 76 people
- Sponsor
- Boston Scientific Corporation
Stage I Uterine Sarcoma AJCC v7, Uterine Corpus Leiomyosarcoma
Gemcitabine Hydrochloride and Docetaxel Followed by Doxorubicin Hydrochloride or Observation in Treating Patients With High-Risk Uterine Leiomyosarcoma Previously Removed by Surgery
This randomized phase III trial studies how well gemcitabine hydrochloride and docetaxel followed by doxorubicin hydrochloride work compared to observation in treating patients with high-risk uterine leiomyosarcoma previously…
- Trial name
- NCT01533207
- Testing
- Clinical Observation, Docetaxel, Doxorubicin Hydrochloride
- Where
- 623 sites in United States, Belgium and 6 more
- Volunteers
- 38 people
- Sponsor
- Gynecologic Oncology Group
Ovarian Neoplasms
Cancer Loyalty Card Study
Approximately 7,400 new cases of ovarian cancer are diagnosed each year in the United Kingdom (UK), and with over 4,000 women dying from the disease each year it is a particularly lethal form of cancer.
- Trial name
- CLOCS (NCT03994653)
- Testing
- Risk Factor Questionnaire, Clinical Questionnaire
- Where
- United Kingdom
- Volunteers
- 963 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Restless Legs Syndrome
Non-interventional Observational Study on the Influence of Pramipexole on Sensory Symptoms of Restless Legs Syndrome (RLS)
The main goal of this open-label, prospective, non-controlled, non-interventional post marketing surveillance study is to evaluate how pramipexole treatment works when applied in actual practice.
- Trial name
- NCT00887289
- Where
- 784 sites in Germany
- Volunteers
- 1,504 people
- Sponsor
- Boehringer Ingelheim
Interstitial Lung Disease, Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Anti-neutrophil Cytoplasmic Antibody in Interstitial Lung Disease.
The purpose of this study is to investigate the clinical features and long-term outcome of anti-neutrophil cytoplasmic antibody (ANCA)-positive interstitial lung disease (ILD) and assess the difference between microscopic…
- Trial name
- NCT04413149
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking Union Medical College Hospital