Clinical trials: Observational Cohort Study
Zika Virus Disease (Disorder)
Zika in Infants and Pregnancy (ZIP)
The overall objective of this multisite, multicountry Zika in Infants and Pregnancy (ZIP) study is to assess the strength of the association between Zika virus infection (ZIKV) during pregnancy and adverse maternal/fetal outcomes…
- Trial name
- NCT02856984
- Where
- 10 sites in Brazil, Colombia and 4 more
- Volunteers
- 6,461 people, healthy volunteers welcome
- Sponsor
- RTI International
Parkinsons Disease (PD)
Neuroimaging of Parkinson's
Parkinson's Disease (PD) is a neurodegenerative disorder caused by dysfunction in both subcortical structures and the cortex. The investigators recently discovered a new brain system called the Somato-Cognitive Action Network…
- Trial name
- NCT07024875
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Polycystic Kidney Disease
Early PKD Observational Cohort Study
This observational study will collect blood and urine and clinical information from individuals with early-stages of polycystic kidney disease (PKD), their unaffected siblings and normal volunteers to create a biobank, also…
- Trial name
- EPOC (NCT02936791)
- Where
- 3 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Diabetes, Gestational
Continuous Glucose Monitoring for Various Degrees of Glucose Intolerance
Diabetes mellitus affects roughly 8% of pregnancies but is associated with significant perinatal and maternal morbidity, with 6% of pregnancies affected by gestational diabetes mellitus (GDM).
- Trial name
- NCT05491954
- Testing
- Dexcom G6
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Pediatric Obstructive Sleep Apnea, Cognition
Observational Study on the Impact of Obstructive Sleep Apnea on Executive Function and Empathy Development in Children
This study aims to investigate the effects of obstructive sleep apnea (OSA) on executive function and empathy development in children aged 3-12 years.
- Conditions
- Pediatric Obstructive Sleep Apnea, Cognition, Empathy, EEG
- Trial name
- OSA-EFED (NCT06850220)
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Soochow University
Cardiovascular Diseases, COPD
The Cartagena Cohort Study
Cardiovascular and respiratory diseases are the first and third cause of death, respectively. Cardiovascular risk is known to increase in groups with impaired lung function; however, the mechanisms behind this association are not…
- Conditions
- Cardiovascular Diseases, COPD, Lung Function Decreased, Atherosclerosis
- Trial name
- CaReS (NCT05339048)
- Testing
- Genetic risk variants, Diet, Physical activity
- Where
- Colombia
- Volunteers
- 619 people, healthy volunteers welcome
- Sponsor
- Universidad de Cartagena
Alzheimer's Disease (AD)
Cognitive Health in Ageing Register: Investigational and Observational Trial Studies in Dementia Research (CHARIOT): Prospective Readiness Cohort (PRO) Longitudinal Study
Alzheimer's disease is a degenerative condition affecting the brain and is the most frequent form of dementia in older adults. Dementia is currently a major healthcare issue in the UK, affecting approximately a million people.
- Trial name
- CPLS (NCT06953167)
- Where
- United Kingdom
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Monkey Pox
Observational Mondkeypox Pregnancy Cohort
PREGMPOXCO study addresses the escalating Mpox virus (MPXV) infections among pregnant women in South Kivu, DRC following a novel MPXV sub-lineage, predominantly transmitted through heterosexual contact, stressing critical gaps in…
- Trial name
- PREGMPOXCO (NCT06442501)
- Testing
- routine care
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Robert Colebunders
Anterior Cruciate Ligament Injuries, Knee Injuries
Evaluation of Vastus Medialis Muscle Inhibition in Indoor Soccer Players With and Without ACL Injury
The Anterior Cruciate Ligament (ACL) is vital for knee stability, and ACL injuries in futsal can lead to long-term issues. Reconstruction surgery may be affected by Anthrogenic Muscle Inhibition (AMI), especially in the vastus…
- Trial name
- NCT06599164
- Testing
- Anthrogenic Muscle Inhibition (AMI) Assessment Protocol
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Upper Respiratory Tract Infections
Birth Cohort Study for Respiratory Infections
The primary objectives are to evaluate relationship between nasopharyngeal microbial colonization and the occurrence of AOM or pneumonia in infants.
- Trial name
- NCT02361164
- Where
- Bangladesh
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Ischemic Stroke, Ischemic Cerebrovascular Disease
Clinical Evaluation of New Biomarkers for Ischemic Cerebrovascular Disease
The goal of this single-center prospective observational study is to identify and evaluate new biomarkers for ischemic cerebrovascular disease (ICVD) to aid in early diagnosis, individualized treatment planning, and prognosis…
- Trial name
- NCT06890702
- Testing
- biomaker levels
- Where
- 2 sites in China
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Healthy, Immune System and Related Disorders
The Healthy Human Global Project - Hong Kong (HHGP-Hong Kong)
The Healthy Human Global Project-Hong Kong aims to elucidate the heritable and non-heritable factors that drive immunological variance within a healthy population in Hong Kong.
- Trial name
- NCT05174624
- Testing
- No intervention
- Where
- China
- Volunteers
- 1,026 people, healthy volunteers welcome
- Sponsor
- Centre for Immunology & Infection
HIV, Metabolic Syndrome
Inflammation in HIV/AIDS-InflammAIDS
The human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) pandemic still represents a major public health problem with 41 million people currently living with HIV worldwide.
- Conditions
- HIV, Metabolic Syndrome, Molecular Biology, Flow Cytometry
- Trial name
- InflammAIDS (NCT07367867)
- Where
- Chile
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Universidad de Magallanes
Whooping Cough
The Safety of Boostrix Following Routine Immunization of Pregnant Women
The purpose of this study was to assess the safety of Boostrix administered on or after the first day of the 27th week of pregnancy by conducting a post-marketing study that provided safety information to the public and…
- Trial name
- NCT03463577
- Testing
- Safety assessment following routine immunization with Boostrix
- Where
- United States
- Volunteers
- 65,783 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Ventral Hernia, Umbilical Hernia
Prospective Study Of A Size Tailored Approach To Repair Umbilical And Epigastric Primary Ventral Hernias
Primary ventral hernias, such as umbilical and epigastric hernias, are best repaired with abdominal wall reinforcement by mesh implantation.
- Conditions
- Ventral Hernia, Umbilical Hernia, Epigastric Hernia
- Trial name
- SITUP (NCT01639118)
- Where
- Belgium
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Infective Organism Causing Respiratory Diseaseand Meningitis
A Prospective Household Observational Cohort Study of Influenza, Respiratory Syncytial Virus and Other Respiratory Pathogens Community Burden and Transmission Dynamics in South Africa
Title: A Prospective Household observational cohort study of Influenza, Respiratory Syncytial virus and other respiratory pathogens community burden and Transmission dynamics in South Africa (The PHIRST Study) This study will…
- Trial name
- PHIRST-SA (NCT02519803)
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- National Institute for Communicable Diseases, South Africa
Huntington Disease, Huntington's Disease
REGISTRY - an Observational Study of the European Huntington's Disease Network (EHDN)
This is a multi-centre, multi-national, prospective, observational study of Huntington's disease (HD) with a control group of volunteers to: obtain natural history data on many HD mutation carriers and individuals who are part of…
- Trial name
- REGISTRY (NCT01590589)
- Where
- 140 sites in Austria, Belgium and 15 more
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- European Huntington's Disease Network
Thoracic Anesthesia, One Lung Ventillation (OLV)
Association Between One Lung Ventilation and Myocardial Injury Markers (Troponin T and I) in Thoracic Surgical Procedures (OLVTIS)
This prospective single-group cohort study aims to investigate the association between the One-Lung Ventilation (OLV) technique and myocardial injury, as measured by postoperative Troponin T and Troponin I levels, in patients…
- Trial name
- OLVTIS (NCT07302243)
- Where
- Indonesia
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Universitas Jenderal Soedirman
Severe Infection and Non-injury Death
SEPSIS Observational Cohort Study in Young Infants in Bangladesh
Globally, infectious diseases such as sepsis, meningitis and pneumonia are among the leading causes of neonatal deaths. A recent observational study in South Asia highlighted the contribution of both bacterial and viral…
- Trial name
- NCT04012190
- Where
- 2 sites in Bangladesh
- Volunteers
- 2,083 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Respiratory Tract Infections, Gastrointestinal Infections
Observational Research in Childhood Infectious Diseases Study
In this study, the investigator will be approaching pregnant women to undertake 2 years of weekly respiratory and nappy specimen collection from their healthy new born infant.
- Trial name
- ORChID (NCT01304914)
- Where
- 2 sites in Australia
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- The University of Queensland