Clinical trials: Observational Study
Guillain-barre Syndrome
Efficacy of Intravenous Gamma Globulin on Guillain-Barre Syndrome
Guillain-barre syndrome (GBS) is an acute immune-mediated polyneuropathy. Intravenous Gamma globulin is an effective therapy.Although high doses of gamma globulin are clinically effective, the patient's recovery and clinical…
- Trial name
- NCT04303962
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ning Wang, MD., PhD.
Cardiovascular Diseases
Study of the Effectiveness and Safety of Niaspan ® in the Treatment of Lipid Abnormalities in Latin America
Post-Marketing Observational study of Niaspan® tablet in accordance with each country regulations. This study will be conducted in a prospective, single-arm, multi-center format.
- Trial name
- NCT01200160
- Testing
- Niacin
- Where
- 22 sites in Colombia, Mexico and 1 more
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Abbott
Dog Bite
Observation Study an Immunogenicity Modified TRC-ID Regimen With CPRV With or Without Rabies Immunoglobulin in Children
To determine Immunogenicity and Safety Study of Modified TRC-ID Regimen with A New Chromatographically Purified Vero Cell Rabies Vaccine (SPEEDA®) as post exposure rabies intradermal regimen with or without Rabies Immunoglobulin…
- Trial name
- NCT02339896
- Testing
- rabies vaccine
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Queen Saovabha Memorial Institute
Ciprofol
Changes of Ciprofol Dosage and Bispectral Index Required for Loss of Consciousness in Patients of Different Ages
This study aims to explore dose requirements for loss of consciousness and bispectral index changes during general anesthesia induction with ciprofol in patients of different ages, providing a reference for its rational clinical…
- Trial name
- NCT07148596
- Testing
- It is an observational study without any intervention measures.
- Where
- China
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
Sepsis, Inflammatory Response
Correlation of Memory CD8+ T Cells With Sepsis Severity and Mortality: a Single-center, Unblinded, Prospective, Non-interventional, Observational Study
Sepsis is defined as a life-threatening organ dysfunction that is caused by a dysregulated host response to infection. Severe sepsis is the most common cause of death among critically ill patients in non-coronary intensive care…
- Trial name
- NCT05875740
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lead, Toxicology
Potential Lead Exposure Through Eating Self-harvested Wild Game
This is a clinical research protocol to determine the feasibility of assessing lead levels in hunters who use lead projectiles. This study will determine if it is possible to perform an interventional double-blind…
- Trial name
- NCT02775890
- Testing
- Eating wild game shot with lead bullets
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Nelson Marlborough Institute of Technology
Keratoconus
The Collagen Factors of Rapid Progression of Keratoconus in Children.
The purpose of this observational study was to understand the differences in clinical features and mechanisms of keratoconus between children and adults.
- Trial name
- KCLD (NCT06722937)
- Testing
- Observation
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Asthma
REALL: A Retrospective Observational Study to Compare the Effectiveness and Cost-Effectiveness Between Different Step-3 Asthma Treatment Strategies
This is a retrospective observational study utilising anonymised individual patient clinical and prescribing information routinely collected by UK General Practitioners (GPs).
- Trial name
- REALL (NCT00628563)
- Where
- United Kingdom
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Malaria
Phase 1b Malaria Clinical Trial Using Argemone Mexicana in Healthy Adults in Mali
The main objective is to study the pharmacokinetics, pharmacodynamics and tolerability of the decoction of the aerial parts of Argemone mexicana (AM), administered in healthy volunteers.
- Trial name
- NCT01645254
- Testing
- Argemone mexicana
- Where
- Mali
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Bamako
Axial Spondyloarthritis, Crohn Disease
MRE as a Screening Tool for axSpA in IBD
This study aims to assess the effectiveness (specificity and sensitivity) of using magnetic resonance enterography (MRE) as a screening tool for axial spondyloarthritis (axSpA) in patients with Crohns disease.
- Trial name
- ProSpA-CD (NCT03817983)
- Testing
- MRE review for evidence of axSpA in SIJs, Clinical assessment and dedicated MRI of the spine and pelvis
- Where
- United Kingdom
- Volunteers
- 259 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Maternal Death During Childbirth
Critical Delays in Cardiopulmonary Resuscitation During Simulated Obstetric Crisis: a Prospective Observational Study.
Maternal cardiac arrest is underreported and continues to occur at rate of 1:20,000 pregnancies. Despite being predominantly younger patients, survival rates among pregnant women are poor with one case series reporting a survival…
- Trial name
- NCT04050631
- Testing
- maternal arrest simulation on L&D floor
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- KidSIM Simulation Program
Normal CT Scan, Dysplasic Disease
Dose-Quality Study in the Temporal Bone Computed Tomography in Routine Care
Because of the complexity of the structures studied, imaging the temporal bone requires compliance with a number of image quality criteria, in order to achieve optimum spatial resolution of the most clinically relevant anatomical…
- Conditions
- Normal CT Scan, Dysplasic Disease, Tumoral Disease, Infectious Disease
- Trial name
- NCT06827106
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aix Marseille Université
COVID-19, Sars-CoV-2 Infection
Efficacy, Immunogenicity, and Safety of TURKOVAC Vaccine Versus the CoronaVac Vaccine Against COVID-19 in Healthy Adolescent
This study is a multi-center, randomized, national, observer-blinded, active-controlled phase IIB clinical trial to determine the efficacy, immunogenicity, and safety of two-doses of inactive COVID-19 vaccine (TURKOVAC) vaccine…
- Trial name
- NCT05230940
- Testing
- TURKOVAC, CoronaVac
- Where
- 14 sites in Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Health Institutes of Turkey
Alzheimer Disease, Early Onset, Parkinsons Disease with Dementia
Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease
The goal of this Multicenter observational pilot study is to Compare the specifics of musical engagement (behaviors related to music in everyday life) in subjects aged over 60 with Alzheimer s disease, Parkinson s disease and…
- Conditions
- Alzheimer Disease, Early Onset, Parkinsons Disease with Dementia, Non Pharmacological Intervention
- Trial name
- MUSENGAGE (NCT06688968)
- Testing
- neuropsychologist interview, questionnaire
- Where
- 3 sites in France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Inguinal Hernia
SetUp Study for HugoTM RAS Inguinal Hernia Repair
The goal of this observational cohort study is to evaluate the evolution of the operative time in performing robotic-assisted laparoscopic inguinal hernia repair (rTAPP) during the learning curve of the first 50 patients using…
- Trial name
- SUSHI (NCT06599515)
- Testing
- robotic surgical platform
- Where
- 2 sites in Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Transgender Persons
Transgender Observational Performance
The study will evaluate the sports capabilities of transgender women mainly in terms of muscular strength and aerobic capacity (VO2max).
- Trial name
- TOP (NCT05337865)
- Testing
- Aerobic exercise test.
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Instituto Brasileiro de Controle do Cancer
Breast Cancer, Fatigue
The Role of Circadian Rhythms in Cancer-Related Symptoms
Emerging evidence indicates that circadian rhythms may be disrupted following cancer and its treatment, and that circadian rhythm disruption may be an underlying pathophysiological mechanism of cancer- and cancer…
- Conditions
- Breast Cancer, Fatigue, Cognitive Impairment, Sleep
- Trial name
- CHRONO (NCT04401189)
- Where
- Denmark
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Observation Safety
Postmarketing Safety Study of Q/LAIV in Subjects 2 Through 49 Years of Age
This is an observational post-marketing study conducted in children and adults immunized with Q/LAIV as part of routine clinical practice at Kaiser Permanente Northern California (NCKP) sites.
- Trial name
- NCT01985997
- Where
- United States
- Volunteers
- 95,000 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
Neurological Disease, Motor Disorders
Technological Devices and Home Automation System in Neurological Rehabilitation
The use of home automation system may be useful in rehabilitation to collect data about the environment and the amount of therapy.
- Trial name
- SMART (NCT06270420)
- Testing
- Technological Motor Rehabilitation
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Hyperuricosuria, Hypocitraturia
Comparison of Different Methods for Measuring Urinary Oxalate and Citrate: An Observational Study
This observational study aims to compare three different laboratory methods for measuring urine oxalate and citrate concentrations.
- Trial name
- Comparison of (NCT06916559)
- Where
- China
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University