Clinical trials: Observatory
Trauma, Arthropathy Shoulder
FH ORTHO Shoulder Observatory
This study is a real-life observatory designed to collect long-term clinical data on patients who have undergone shoulder joint replacement or repair following shoulder trauma.
- Trial name
- NCT06511856
- Testing
- ARROW
- Where
- 3 sites in France
- Volunteers
- 500 people
- Sponsor
- FH ORTHO
Irritable Bowel Syndrome, Dyspepsia
Functional Digestive Disorders Observatory
Functional digestive pathologies are defined by symptoms such as functional dyspepsia, gastroesophageal reflux, irritable bowel syndrome, gastroesophageal reflux, functional constipation, functional diarrhea, functional bloating…
- Conditions
- Irritable Bowel Syndrome, Dyspepsia, Functional Constipation, Faecal Incontinence
- Trial name
- OTFI (NCT04918329)
- Testing
- Observational study
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Rouen
Anemia, Acute Myeloid Leukemia
Observatory of the Prescription of Erythropoietin as Treatment of Anemia Induced by Chemotherapy or Allograft Conditioning Among the Patients With a Haematological Malignancy
Anemia concerns a lot of patients with cancer and affects their quality of life (QOL). Numerous studies in oncology have demonstrated the benefit of erythropoiesis-stimulating agents (ESA) in the treatment of anemia.
- Trial name
- EPREX/LAM-ALLO (NCT02860598)
- Where
- France
- Volunteers
- 104 people
- Sponsor
- Hospices Civils de Lyon
Patient With Dyslipidemia
Assessment of Compliance With European and French Guidelines for the Management of Dyslipidaemias
Cardiovascular disease (CVD) due to atherosclerosis of the arterial vessel wall and to thrombosis is the foremost cause of premature mortality and of disability-adjusted life years in Europe, and is also increasingly common in…
- Trial name
- OBDYSLIP (NCT03449784)
- Testing
- Detection of patients with dyslipidemia
- Where
- France
- Volunteers
- 977 people
- Sponsor
- University Hospital, Montpellier
Diabetes
Skin Manifestations Associated With Adhesives in Diabetes Technology Tools
The use of technological tools in the treatment of diabetes has intensified and become common in recent years. Many of these systems adhere to the skin with an adhesive in place between 2 and 14 days.
- Trial name
- CUTADIAB (NCT04853810)
- Testing
- CUTADIAB questionnaire
- Where
- 4 sites in France
- Volunteers
- 851 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pulmonary Arterial Hypertension of Congenital Heart Disease
Observatory of Pulmonary Arterial Hypertension of Congenital Heart Disease
The complex congenital cardiac malformations are a significant number of different diseases, each having specific natural histories.
- Trial name
- ItinerAir (NCT02260362)
- Where
- France
- Volunteers
- 349 people
- Sponsor
- French Cardiology Society
Sedentary Behavior, Exercise
Physical Activity Observatory of Castilla-La Mancha
The OBAFIT project aims to examine the patterns of physical activity, sedentary activity and health-related physical fitness of the boys and girls enrolled in schools of Primary Education and Secondary Education in Castilla-La…
- Conditions
- Sedentary Behavior, Exercise, Physical Fitness
- Trial name
- OBAFIT (NCT04994340)
- Where
- Spain
- Volunteers
- 3,280 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Nasopharyngeal Carriage, Children, Only
Nasopharyngeal Carriage of S. Pneumoniae
This nasopharyngeal (NP) carriage surveillance study was requested by the European Agency for the Evaluation of Medicinal Products as a post-licensing commitment to determine whether the use of the pneumococcal conjugate vaccines…
- Conditions
- Nasopharyngeal Carriage, Children, Only, Antibiotic Resistant Strain
- Trial name
- NCT04460313
- Testing
- nasopharyngeal sample (mandatory), Stools collection or anorectal swab samples (optional), nasopharyngeal sample (optional)
- Where
- France
- Volunteers
- 29,360 people, healthy volunteers welcome
- Sponsor
- Association Clinique Thérapeutique Infantile du val de Marne
Polycythemia Vera, Essential Thrombocythemia
Myeloproliferative Neoplastic Diseases Observatory From Brest
All patients diagnosed or followed in Brest University Hospital for Philadelphia negative myeloproliferative neoplasms will be included in this observational study.
- Conditions
- Polycythemia Vera, Essential Thrombocythemia, Primary Myelofibrosis
- Trial name
- OBENE (NCT02897297)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Brest
Parkinson Disease, Neurodegenerative Diseases
Mobile Parkinson Observatory for Worldwide, Evidence-based Research (mPower)
The purpose of this study is to understand variation in the symptoms of Parkinson disease. This study uses an iPhone app to record these symptoms through questionnaires and sensors.
- Conditions
- Parkinson Disease, Neurodegenerative Diseases, Movement Disorders, Central Nervous System Diseases
- Trial name
- mPower (NCT02696603)
- Testing
- Participant self-assessment surveys, Phonation, Gait and balance
- Where
- United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Sage Bionetworks
Aging, Inpatients
Epidemiological Observatory on the Health Conditions of Inpatients Aged 65 or Older at the INRCA Research Hospitals
The goal of this research study is to collect clinical data, comprehensive geriatric assessment, risk factors, biological data and blood samples from inpatients aged 65 and older at the INRCA research hospitals (Italy).
- Trial name
- report-AGE (NCT01397682)
- Testing
- blood sample collection
- Where
- 4 sites in Italy
- Volunteers
- 2,250 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Immune Thrombocytopenia
Observatory of Immunological Thrombopenic Purpura in the Brest Region
Database of patients with ITP, diagnosed, treated and followed in the Brest University Hospital.
- Trial name
- OPTIMIST (NCT06556888)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Brest
Chronic Lymphoid Leukaemia
Chronic Lymphoid Leukaemia Observatory in Finistere Area, France
Brief Summary: The purpose of the OFICE registry is to characterize and describe the CLL patients' population from the Finistere area and evaluates the association between different patient characteristics, prognosis and…
- Trial name
- OFICE (NCT03294980)
- Where
- France
- Volunteers
- 3,000 people
- Sponsor
- University Hospital, Brest
Persistent Polyclonal B-Cell Lymphocytosis
Epidemiologic Study of Persistent Polyclonal B-cell Lymphocytosis (PPBL)
The main purpose of this study is the description of all French cases of PPBL and the establishment of minimal criteria for the pathology diagnosis and its follow-up.
- Trial name
- LPLB (NCT03296046)
- Testing
- Blood test
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Central Hospital, Nancy, France
Antiphospholipid Syndrome (APS), Direct Oral Anticoagulants (DOACs)
OBServaToIre interNational Des Patients AnTiphospholipidEs traités Par Anticoagulants Oraux Directs
This registry will make it possible to collect large-scale data on SAPL patients, particularly those treated with DOACs, in order to better assess the frequency of thrombotic and hemorrhagic events in this population of…
- Conditions
- Antiphospholipid Syndrome (APS), Direct Oral Anticoagulants (DOACs), Thrombotic and Bleeding Events, Safety
- Trial name
- OBSTINATE 2 (NCT06929182)
- Testing
- "non-high risk" thrombotic APS patients treated with DOAC
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Central Hospital, Nancy, France
Congenital Heart Disease
Northwest Adult Congenital Heart Disease Observatory
The incidence of congenital heart disease is about 8 per thousand live births. Thanks to advances in cardiac surgery, 90% of children born with heart defects reach adolescence and adulthood.
- Trial name
- CARL (NCT02897323)
- Testing
- description
- Where
- France
- Volunteers
- 4,000 people
- Sponsor
- University Hospital, Caen
Thymic Epithelial Tumor
French National Observatory of Patients With Thymic Epithelial Tumor
RYTHMIC (Réseau tumeurs THYMiques et Cancer) is a French nationwide network for TET with the objective of territorial coverage by regional expert centers and systematic discussion of patients management at national tumor board.
- Trial name
- RYTHMIC (NCT02724696)
- Where
- 2 sites in France
- Volunteers
- 3,262 people
- Sponsor
- Intergroupe Francophone de Cancerologie Thoracique
AML, Adult
OBServatory of Compassionate Use of IVOsidenib in France for Patients With Acute Myeloid Leukemia
Mutations in IDH genes are found in numerous cancers and more specifically in acute myeloid leukemia (AML). These mutations target specific amino acids, at positions 140 or 172 of IDH2, and 132 of IDH1.
- Trial name
- NCT06377579
- Where
- 21 sites in France
- Volunteers
- 250 people
- Sponsor
- French Innovative Leukemia Organisation
Neurologic Disorder, Psychiatric Disorder
Observatory of Psychiatric Symptoms and Their Somatic Causes in Urgent Medical Care
Use of emergency department for psychiatric symptoms always addresses the question of a potential somatic cause to the symptoms.
- Trial name
- OPOSSUM (NCT04726449)
- Testing
- Screening for acute confusional state
- Where
- France
- Volunteers
- 148 people
- Sponsor
- Hospices Civils de Lyon
Metastatic Colorectal Cancer, Colorectal Neoplasms
Resection Observatory
Primary Objective: -Evaluate the resection rate (R0/R1) in current practice for aflibercept in combination with irinotecan plus 5-fluorouracil (FOLFIRI) in patients treated for metastatic colorectal cancer (mCRC) after failure of…
- Trial name
- NCT05178745
- Testing
- Fluorouracil, Aflibercept, Irinotecan
- Volunteers
- 140 people
- Sponsor
- Sanofi