Clinical trials: Obsessive Compulsive Disorder, active
Obsessive-Compulsive Disorder
Accelerated Rotational Field Deep TMS for Treating OCD
A Prospective Double Blind Randomized Controlled Trial to Evaluate the Efficacy and Durability of the BrainsWay Rotational Field Deep Transcranial Magnetic Stimulation (Deep TMS) in Obsessive-Compulsive Subjects
- Trial name
- NCT07116785
- Testing
- BrainsWay Deep TMS HAC/H7-Coil
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Ben-Gurion University of the Negev
Obsessive-Compulsive Disorder, Tic Disorder
Pathogenesis of Pediatric Obsessive-compulsive Disorder: Based on the Microbiota-gut-brain Axis
This study aims to investigate the characteristics of the microbiota-gut-brain axis in pediatric patients with obsessive-compulsive disorder (OCD) through performing an integrated analysis of gut microbiota, serum metabolomics…
- Trial name
- NCT06754319
- Where
- China
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Obsessive-compulsive Disorder
Evaluation Study: Obsessive-compulsive Disorders in Childhood and Young Adulthood
Obsessive-compulsive disorders are very damaging illnesses that can already manifest in childhood and adolescence. With an average prevalence from 1 - 3%, they are one of the most frequently diagnosed psychiatric illness in these…
- Trial name
- NCT04723485
- Where
- Switzerland
- Volunteers
- 625 people
- Sponsor
- Susanne Walitza
ADHD, Obsessive Compulsive Disorder (OCD)
Role of Theta Frequency Oscillations in Proactive and Reactive Control Processes in Youth With Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD)
Background: Attention deficit hyperactivity disorder (ADHD) is common in children. It can cause problems with attention and the ability to control actions and impulses.
- Conditions
- ADHD, Obsessive Compulsive Disorder (OCD), Healthy Volunteer
- Trial name
- NCT07566468
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Obsessive Compulsive Disorder (OCD), Comorbid Post-Traumatic Stress Disorder and OCD
ERP to Improve Functioning in Veterans With OCD
Obsessive compulsive disorder (OCD) is a debilitating psychiatric illness impacting work, social, and family functioning. Exposure and Response Prevention (ERP) is the sole evidence-based psychotherapy for OCD; however, no…
- Trial name
- NCT05240924
- Testing
- Exposure and Response Prevention, Stress Management Training
- Where
- 19 sites in United States
- Volunteers
- 160 people
- Sponsor
- VA Office of Research and Development
Obsessive - Compulsive Disorder
Neural Mechanisms of the Sensorymotor Circuit in Sensory Phenomena in OCD
The goal of this clinical study is to investigate the neural mechanisms of abnormal sensory phenomena in patients with Obsessive-Compulsive Disorder and to evaluate whether modulation of the insula-supplementary motor area…
- Trial name
- NCT07480408
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Obsessive-Compulsive Disorder
Ventral Capsulotomy for Intractable OCD
Obsessive-compulsive disorder impacts 1-2 percent of the population. Unfortunately, about fifteen percent of patients fail to benefit from existing therapies.
- Trial name
- NCT05659082
- Testing
- Laser Interstitial Thermal Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Butler Hospital
Obsessive-Compulsive Disorder
Mindfulness-Based Interventions for OCD
Obsessive-compulsive disorder (OCD) is a severe and debilitating anxiety disorder afflicting about 2% of the population. It is characterized by the presence of recurrent obsessions and/or compulsions that are time consuming and…
- Trial name
- MindOC (NCT04914923)
- Testing
- Muse, Cognitive Behaviour Therapy (CBT), Mindfulness-Based Cognitive Therapy (MBCT)
- Where
- 2 sites in Canada
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Obsessive-Compulsive Disorder
Valbenazine in Obsessive Compulsive Disorder
The primary aim of the study is to examine the efficacy and safety of valbenazine in adults with moderate to severe obsessive-compulsive disorder (OCD).
- Trial name
- NCT07111988
- Testing
- Valbenazine
- Volunteers
- 30 people
- Sponsor
- University of Chicago
Obsessive-Compulsive Disorder
Efficacy of Nitrous Oxide in OCD: Pilot Study
This study investigates whether the commonly used and well-tolerated inhaled anesthetic nitrous oxide can rapidly improve symptoms of OCD.
- Trial name
- NCT03826693
- Testing
- Nitrous Oxide, Nitrogen
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Stanford University
Obsessive-Compulsive Disorder, Tricholemmoma
Neural Mechanisms of Response Inhibition Training for OCRD
The impaired ability to suppress an inappropriate but pre-potent response (response inhibition; RI) characterizes several debilitating clinical problems, including obsessive-compulsive and related disorders (OCRD) such as…
- Conditions
- Obsessive-Compulsive Disorder, Tricholemmoma, Skin-Picking
- Trial name
- OCRD (NCT05377125)
- Testing
- Computerized cognitive training
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Wisconsin, Milwaukee
Obsessive-Compulsive Disorder, OCD
Personalized DBS for OCD Guided by Stereoencephalography Mapping
This is a double-blinded, randomized, crossover study design for SEEG-guided 4-lead DBS for treatment-refractory OCD, followed by open label stimulation for an additional 6 months.
- Trial name
- NCT06347978
- Testing
- Deep Brain Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Andrew Moses Lee, MD, PhD
Obsessive-Compulsive Disorder
Cortical Stimulation to Treat Obsessive Compulsive Disorder
The purpose of this study is to identify abnormal brain signals associated with Obsessive Compulsive Disorder (OCD) and psychiatric symptoms and to investigate novel therapeutic stimulation sites.
- Trial name
- NCT04958096
- Testing
- Standard Therapeutic Deep Brain Stimulation, Cortical Stimulation for PFC, Cortical Stimulation for ACC
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Andrew Moses Lee, MD, PhD
Trichotillomania (Hair-Pulling Disorder), Dermatillomania
Aripiprazole in Body Focused Repetitive Behaviors
This study is 6 weeks long and involves subjects taking aripiprazole or placebo. If they are randomly assigned to the aripiprazole arm and are eligible to participate in the study, they will begin by taking 5mg once daily of…
- Trial name
- NCT05545891
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Chicago
Obsessive-Compulsive Disorder (OCD)
Preliminary Explorative Study of Magnetic Resonance-Guided Focused Ultrasound Surgery in Refractory Obsessive-Compulsive Disorder Patients
The goal of this clinical trial is to evaluate If magnetic resonance-guided focused ultrasound works to treat refractory obsessive-compulsive disorder in adults.
- Trial name
- NCT06816511
- Testing
- magnetic resonance-guided focused ultrasound surgery, MRgFUS
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- National Taiwan University Hospital
Obsessive-Compulsive Disorder (OCD)
Feasibility of Modulating Cognitive Control in OCD
This study tests out procedures to look at whether a type of brain stimulation called transcranial magnetic stimulation impacts flexible shifts in behavior in obsessive-compulsive disorder (OCD).
- Trial name
- NCT07419009
- Testing
- continuous theta-burst transcranial magnetic stimulation (cTBS)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Obsessive-Compulsive Disorder (OCD)
Aerobic Exercise and Obsessive-Compulsive Disorder Symptoms
The purpose of this study is to examine the acute effects of exercise on cognitive flexibility and symptom reactivity. The main questions it aims to answer are: Does moderate intensity physical activity reduce subjective…
- Trial name
- NCT07103902
- Testing
- Moderate-Intensity Exercise, Low-Intensity Exercise
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Yale University
Behavioral Activation, Major Depressive Disorder
Pharmacogenomics of Selective Serotonin Reuptake Inhibitor (SSRI)-Induced Behavioural Activation
The purpose of this study is to identify and validate a panel of genetic markers associated with selective serotonin reuptake inhibitors (SSRI)-induced behavioural activation in children and youth with major depressive disorder…
- Conditions
- Behavioral Activation, Major Depressive Disorder, Anxiety Disorders, Antidepressant Drug Adverse Reaction
- Trial name
- PGx-SImBA (NCT06763081)
- Testing
- Not applicable- observational study
- Where
- 2 sites in Canada
- Volunteers
- 160 people
- Sponsor
- University of Manitoba
Obsessive-Compulsive Disorder, Body Dysmorphic Disorders
Imagery Rescripting as a Stand-alone Treatment for OCD and BDD.
The goal of this multiple baseline case series study is to test the effect of imagery rescripting (ImRs) in Obsessive Compulsive Disorder (OCD) and Body Dysmorphic Disorder (BDD).
- Conditions
- Obsessive-Compulsive Disorder, Body Dysmorphic Disorders, Anxiety Disorders
- Trial name
- NCT06346301
- Testing
- Imagery rescripting
- Where
- Netherlands
- Volunteers
- 36 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
OCD
A Clinical Protocol for VR-Assisted CBT Targeting Quality of Life Outcomes for OCD
This study aims to evaluate the effectiveness of VR interventions in improving the psychological quality of life among OCD patients.
- Trial name
- NCT07857577
- Testing
- VR-CBT, G-VRET
- Where
- Malaysia
- Volunteers
- 36 people
- Sponsor
- National University of Malaysia