Clinical trials: Obsessive Compulsive Disorder (OCD)
Healthy, Mental Disorder
I-123 Brain Studies of Serotonin Metabolism in Psychiatric Patients and Normal Volunteers
Abnormalities in the re-uptake of dopamine and serotonin have been described in various neuropsychiatric disorders and substance abuse.
- Conditions
- Healthy, Mental Disorder, Obsessive Compulsive Disorder, Schizophrenia
- Trial name
- NCT00001771
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Obsessive-Compulsive Disorder
Cognitive Training in Obsessive Compulsive Disorder
This unique study will allow us to observe the neural correlates associated with working memory in an obsessive compulsive disorder (OCD) paradigm.
- Trial name
- CTOCD (NCT02818088)
- Testing
- n-Back (Cognitive Training)
- Where
- South Africa
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Stellenbosch
Obsessive-Compulsive Disorder
The Neurocircuitry of Relief During Avoidance Learning in Patients With Obsessive-compulsive Disorder
To investigate the neuro-mechanisms underpinning persistent avoidance in OCD patients
- Trial name
- AvoidOCD (NCT04685018)
- Testing
- fMRI acquisition
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Obsessive-Compulsive Disorder
Serotonin Transporters in Obsessive-Compulsive-Related Disorders
This study will compare serotonin transporters in patients with obsessive-compulsive disorder (OCD) and healthy volunteers in order to better understand the role of serotonin in OCD.
- Trial name
- NCT00082550
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Hoarding Disorder, Obsessive-Compulsive Disorder
Cognitive Rehabilitation and Exposure Therapy for Geriatric Hoarding
Hoarding disorder (HD) is a chronic, progressive, and debilitating psychiatric condition that leads to devastating personal and public consequences, particularly for older adults.
- Trial name
- CREST (NCT05254015)
- Testing
- Cognitive Rehabilitation and Exposure/Sorting Therapy (CREST), Case Management
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Obsessive-Compulsive Disorder
TMS-induced Plasticity Improving Cognitive Control in OCD
Repetitive transcranial magnetic stimulation (rTMS) has been shown in several previous clinical trials to be an effective treatment for obsessive-compulsive disorder (OCD).
- Trial name
- TIPICCO (NCT03667807)
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Netherlands
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
OCD
The Imaging Genetic Study of the Core Family of Obsessive-compulsive Disorder (OCD) Patient
To investigate the structural/functional abnormalities and the possible genetic endophenotypes of Obsessive-compulsive disorder (OCD) patients and their core families.
- Trial name
- NCT01298622
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kunming Medical University
Obsessive-Compulsive Disorder
Psychiatric Neurosurgery (PNS) for Obsessive Compulsive Disorder (OCD): A Qualitative Analysis of Patient and Family Member Experiences
In this study the investigators will use semi-structured interviews to qualitatively analyse patient and family member experiences with either deep brain stimulation or other forms of psychiatric neurosurgery.
- Trial name
- NCT02537795
- Testing
- deep brain stimulation, anterior capsulotomy
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Autism, Asperger's Syndrome
Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety
Autism spectrum disorders affect as many as 1 out of 88 children and are related to significant impairment in social, adaptive, and school functioning.
- Conditions
- Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder
- Trial name
- NCT01919970
- Testing
- Cognitive Behavioral Therapy, Treatment as usual
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Anxiety Disorders, Obsessive Compulsive Disorder
Evaluating Parenting Styles and Child Temperament Associated With Child Anxiety Disorders
This study will look at similarities and differences in family processes and child temperament among children with and without symptoms of anxiety disorders.
- Trial name
- NCT00517244
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Anxiety, Obsessive Compulsive Disorder
Virtual Reality System to Increase Access to Exposure Therapy for Anxiety and OCD
Cognitive Behavioral Therapy with fear provoking exposures is the most effective therapy for anxiety disorders. Investigators aim to enhance this therapy with the use of virtual reality exposures and to make therapy more…
- Trial name
- NCT02713516
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Obsessive-Compulsive Disorder
Developing Adaptive Treatment Strategies for Children and Adolescents With Obsessive-compulsive Disorder.
Obsessive-compulsive disorder affects approximately 2% of the population, frequently has its onset during childhood or adolescence and is potentially incapacitating.
- Trial name
- SMART (NCT01148316)
- Testing
- fluoxetine, Group cognitive-behavioral therapy
- Where
- Brazil
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Roseli Shavitt
Obsessive-Compulsive Disorder
Decision-making Impairments in OCD: An Integrated Behavioral Economics Model
The investigators are examining whether conditions of ambiguity during decision-making may prime intolerance of uncertainty beliefs (i.e., difficulties coping with ambiguity, unpredictability, and the future) and lead to impaired…
- Trial name
- NCT03420495
- Testing
- Decision-Making Tasks
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Generalized Anxiety Disorder, Major Depressive Disorder
Development of Online EMDR Therapy System and Its Comparative Testing With Face-to-Face EMDR Therapy for Treatment of Anxiety and Depressive Disorders in Pakistan
This study aims at developing an online system for the remote delivery of EMDR therapy in Pakistan. Moreover, this study will compare the efficacy of online EMDR therapy with face-to-face EMDR therapy.
- Conditions
- Generalized Anxiety Disorder, Major Depressive Disorder, Social Anxiety Disorder, Somatic Symptom
- Trial name
- NCT05785312
- Testing
- Online EMDR Therapy System, Face to Face Eye Movement Desensitization & Reprocessing Therapy
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Khushal Khan Khattak Univeristy, Karak, Pakistan
Obsessive-Compulsive Disorder
Modulating Prefrontal Circuits Underlying Behavioral Flexibility in OCD: A TMS Study
This study investigates whether slow-frequency repetitive transcranial magnetic stimulation targeting frontal pole can acutely modulate brain circuits which show abnormal functioning during behavioral flexibility in…
- Trial name
- NCT04165577
- Testing
- rTMS
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Tourette Syndrome, Obsessive-Compulsive Disorder
Sensory Symptoms in Tourette Syndrome and Obsessive-Compulsive Disorder
This study seeks to address two key questions related to sensory dysregulation in Tourette syndrome (TS) and obsessive compulsive disorder (OCD): 1) Is sensory dysregulation in OCD clinically distinct from that in TS? 2) To what…
- Conditions
- Tourette Syndrome, Obsessive-Compulsive Disorder, Sensory Disorders
- Trial name
- SenST-Plus (NCT04335175)
- Testing
- None - observational study
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Obsessive Compulsive Disorder, Major Depressive Disorder
Integrating Pharmacogenomic Testing Into a Child Psychiatry Clinic
The purpose of this study is to examine the feasibility, acceptability, and utility of pharmacogenomic (PGX) testing (specifically for the cytochrome P450 2D6 and 2C19 genes) prior to initiating treatment with an antidepressant…
- Conditions
- Obsessive Compulsive Disorder, Major Depressive Disorder, Anxiety
- Trial name
- PGX (NCT02855580)
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Florida
Obsessive-Compulsive Disorder
Efficacy and Influencing Factors of Deep Transcranial Magnetic Stimulation in the Treatment of OCD
This study aims to explore the efficacy and influencing of accelerated dTMS (deep Transcranial Magnetic Stimulation) treatment in patients with obsessive-compulsive disorder (OCD), and explores the potential neural mechanisms of…
- Trial name
- NCT06692114
- Testing
- Deep Transcranial Magnetic Stimulation, DTMS active
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Zhen Wang
Obsessive-Compulsive Disorder
Unique Electroencephalography (EEG) Markers of Habit Behaviors in Obsessive-Compulsive Disorder (OCD)
This study focuses on explaining the occurrence and development of compulsive behaviors from habit hypothesis. Investigators will study both OCD patients and healthy individuals using Hardwick's forced-response time task(2019)…
- Trial name
- NCT06882902
- Testing
- habit formation training
- Where
- China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Obsessive Compulsive Disorder OCD
Impact of Attention on Obsessive Thoughts Through THOUGHT
Impact of attention on obsessive through the THOUGHT-scale (Troublesome Human Obsessions and Untargeted General Habitual Thoughts Scale): a description of the content of thoughts according to the level of attention demanded by…
- Trial name
- THOUGHTS (NCT05944172)
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris