Clinical trials: Obsessive-Compulsive Behavior
Drug-withdrawal., Drug Abuse
Clinical Studies on the Therapeutic Effects of Mirtazapine on Drug-craving in Cocaine Addicts.
INTRODUCTION. One of the main problems of the treatment of cocaine-dependent patients is the high rate of relapses occurs within the first months after detoxification.
- Conditions
- Drug-withdrawal., Drug Abuse, Drug-induced Depressive State, AOD Craving
- Trial name
- MADC (NCT01949571)
- Testing
- Mirtazapine (REMERON, Schering-Plough-Organon)
- Where
- Mexico
- Volunteers
- 64 people
- Sponsor
- Instituto Nacional de Psiquiatría Dr. Ramón de la Fuente
Parkinson Disease, Obsessive-Compulsive Disorder
Electrophysiology of Brain Activity During Electrode Implantation in Patients Treated With Deep Brain Stimulation
Primary objective Demonstrate functional markers derived from electrophysiological signals recorded during cognitive tests. These markers should make it possible to optimize the targeting procedures of electrode implantation…
- Conditions
- Parkinson Disease, Obsessive-Compulsive Disorder, Epilepsy, Depression
- Trial name
- LFP-DBS (NCT03874611)
- Testing
- electrophysiological data from DBS
- Where
- France
- Volunteers
- 125 people
- Sponsor
- University Hospital, Grenoble
Behavior, Addictive, Cigarette Smoking
Practicing Self-Control Lowers the Risk of Smoking Lapse
The proposed study will investigate the role of self-control in smoking cessation and whether interventions that improve self-control can help reduce the risk of lapsing among smokers who wish to quit.
- Trial name
- NCT00349687
- Testing
- self-control practice
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University at Albany
Sexual Addiction
A Study of Gene Polymorphisms Associated With Specific Presentations of Sexual Addiction
The study is intended to identify gene polymorphisms significantly associated with specific behavioral- and preoccupation-typologies of sexual addiction, and to identify additional potential genetic markers of sexual addiction.
- Trial name
- NCT02844985
- Testing
- No Intervention
- Where
- 8 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- American Foundation for Addiction Research
Substance Dependency, Addiction
Working Memory Training for Substance Dependent Individuals
Background: Substance abusers show impaired working memory (WM) functioning. Promising findings show training WM results in an improved working memory capacity (WMC) and a decrease of clinical symptoms in a range of disorders…
- Conditions
- Substance Dependency, Addiction, Anxiety, Depression
- Trial name
- NCT02119949
- Testing
- Working memory training
- Where
- Netherlands
- Volunteers
- 180 people
- Sponsor
- Erasmus Medical Center
Obsessive Compulsive Disorder
Computer Assisted Cognitive Behavior Therapy for Obsessive Compulsive Disorder: A Comprehensive Stepped-Care Approach
The goal of this project is to improve access to effective treatments for obsessive compulsive disorder (OCD) through the use of web-based cognitive behavioral therapy (CBT) treatment.
- Trial name
- NCT01522287
- Testing
- Computer-Assisted Cognitive Behavior Therapy (BT STEPS)
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Center for Psychological Consultation
HIV
Computer-Assisted HIV Prevention for Young Drug Users
In this study, the investigators are developing and evaluating an interactive, computer-assisted HIV, STD and disease prevention program for young substance abusers that incorporates effective components of both prevention…
- Trial name
- NCT00182585
- Testing
- computer-based HIV, STD & Hepatitis Education, educator-delivered HIV, STD and Hepatitis education
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- National Development and Research Institutes, Inc.
Substance Use Disorders, Eating Disorders
Substance Use and Eating Disorders : Food Craving and Addiction Transfer
Substance Use Disorder (SUD) and Eating Disorders (ED) are severe and persistent disturbances that are associated with significant harm.
- Trial name
- SUED (NCT05315635)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 294 people
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Obsessive-compulsive Disorder
Booster as an Adjunct to Internet-based Cognitive Behavior Therapy (CBT)
In this trial, we test if adding an Internet-based booster program to regular Internet-based cognitive behavior therapy (ICBT) is effective for patients with obsessive-compulsive disorder (OCD).
- Trial name
- NCT01525576
- Testing
- Booster
- Where
- Sweden
- Volunteers
- 98 people
- Sponsor
- Karolinska Institutet
Obsessive-compulsive Disorders and Symptoms, Obsessive-Compulsive Disorder
Inference-Based Cognitive Therapy Versus Exposure and Response Prevention for Obsessive-Compulsive Disorder
Obsessive-compulsive disorder (OCD) is a highly disabling psychiatric illness, characterized by obsessional thoughts that cause patients to perform time-consuming and distressing compulsive rituals.
- Trial name
- RCT_TOC_16 (NCT03677947)
- Testing
- Exposure and response prevention, Inference-based cognitive therapy
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire en santé Mentale de Montréal
Obsessive-Compulsive Disorder
Effectiveness of Sertraline and Cognitive Behavioral Therapy in Treating Pediatric Obsessive-Compulsive Disorder
This study measures the occurrence of certain side effects linked to antidepressant use and evaluates the effectiveness of the medication sertraline plus cognitive behavioral therapy to treat people with obsessive-compulsive…
- Trial name
- NCT00382291
- Testing
- Regular Titration, Slow Titration
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- University of Florida
Hypersexuality, Compulsive Sexual Behavior
Effectiveness of ACT for Problematic Chemsex
Investigation of the efficacy of Acceptance and Commitment Therapy (ACT) for the psychological treatment of problematic chemsex.
- Conditions
- Hypersexuality, Compulsive Sexual Behavior, Sexualized Drug Use (Chemsex)
- Trial name
- ChemACT (NCT06406296)
- Testing
- Acceptance and Commitment Therapy (ACT)
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Universidad Europea de Madrid
Alcoholism, Child Abuse, Sexual
Group Therapies for Reducing HIV-risk Behavior in Women Who Have Survived Childhood Sexual Abuse
This study will evaluate the effectiveness of trauma-focused group therapy for reducing HIV-risk behavior and revictimization among adult women survivors of childhood sexual abuse (CSA).
- Conditions
- Alcoholism, Child Abuse, Sexual, Sexual Abuse, Sexual Behavior
- Trial name
- NCT00220597
- Testing
- Trauma-focused group therapy
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obsessive-Compulsive Disorder
Cortical Stimulation to Treat Obsessive Compulsive Disorder
The purpose of this study is to identify abnormal brain signals associated with Obsessive Compulsive Disorder (OCD) and psychiatric symptoms and to investigate novel therapeutic stimulation sites.
- Trial name
- NCT04958096
- Testing
- Standard Therapeutic Deep Brain Stimulation, Cortical Stimulation for PFC, Cortical Stimulation for ACC
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Andrew Moses Lee, MD, PhD
Social Networks, Addiction
Prevalence of Problematic Use of Social Media
In 2023, French individuals spend an average of two hours per day on social media platforms (SM), primarily Facebook, TikTok, X, YouTube, Instagram, and Snapchat.
- Trial name
- PURPLE (NCT06798480)
- Testing
- Self-administered survey
- Where
- France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Trichotillomania, Obsessive Compulsive Disorder
Marinol in Trichotillomania or Obsessive Compulsive Disorder
The goal of the proposed study is to evaluate the efficacy and safety of dronabinol in individuals with obsessive-compulsive disorder (OCD) or the obsessive-compulsive spectrum disorders, trichotillomania (TTM) or pathological…
- Trial name
- NCT01093976
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Chicago
Food Addiction
Food Addiction Clinical Treatment Program
The purpose of this current study is to establish the feasibility of, and preliminary support for, a clinical treatment program utilizing interventions from various empirically supported treatments for obesity-related eating…
- Trial name
- FACT (NCT04373343)
- Testing
- 16-week Food Addiction Clinical Treatment (FACT) Program
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Wake Forest University Health Sciences
OCD
Personalized Inhibitory Control Training for Compulsive Behavior Change
Obsessive-compulsive disorder (OCD) is a severe mental illness characterized by repetitive behaviors that a person feels compelled to perform.
- Trial name
- NCT03682913
- Testing
- P-CIT protocol
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hebrew University of Jerusalem
Trichotillomania, Hair Pulling Disorder
Milk Thistle in Trichotillomania in Children and Adults
The goal of the proposed study is to evaluate the efficacy and safety of silymarin (milk thistle) in children and adults with trichotillomania.
- Trial name
- NCT02473913
- Testing
- Milk Thistle
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Chicago
fMRI, Alcohol Drinking
Ghrelin for Alcohol Use in Non-Treatment-Seeking Heavy Drinkers
Background: Ghrelin is a hormone in the human body that is mostly produced by the stomach. It makes people feel hungry, and also is connected with the desire to drink alcohol.
- Conditions
- fMRI, Alcohol Drinking, Alcoholism
- Trial name
- NCT01779024
- Testing
- Ghrelin, fMRI, Alcohol
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
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