Clinical trials: Obsessive-Compulsive Disorder, open to volunteers
Obsessive-Compulsive Disorder
Valbenazine in Obsessive Compulsive Disorder
The primary aim of the study is to examine the efficacy and safety of valbenazine in adults with moderate to severe obsessive-compulsive disorder (OCD).
- Trial name
- NCT07111988
- Testing
- Valbenazine
- Volunteers
- 30 people
- Sponsor
- University of Chicago
Depression, Obsessive-Compulsive Disorder
Retrospective Analyses of TrakStar Database
In this study, real-world data will be used to better understand the effects patient characteristics, symptoms and TMS protocol parameters have on clinical outcomes with NeuroStar TMS.
- Conditions
- Depression, Obsessive-Compulsive Disorder, Anxiety Depression
- Trial name
- NCT06917339
- Testing
- NeuroStar Advanced TMS Therapy System
- Where
- United States
- Volunteers
- 156,000 people
- Sponsor
- Neuronetics
Obsessive-Compulsive Disorder
Sonication-based OCD Neurosurgical Intervention Via Capsulotomy
The goal of this clinical trial is to determine if ExAblate MR-guided Focused Ultrasound (MRgFUS) bilateral anterior capsulotomy can be used safely and effectively to relieve symptoms of moderate to severe obsessive compulsive…
- Trial name
- SONIC (NCT06131502)
- Testing
- ExAblate MR-guided Focused Ultrasound Bilateral Anterior Capsulotomy
- Where
- 2 sites in United States
- Volunteers
- 66 people
- Sponsor
- Brigham and Women's Hospital
Lateral Epicondylitis, Medial Epicondylitis
Investigation of Obsessive-Compulsive Disorder in Patients With Elbow Epicondylitis
This study will compare obsessive-compulsive symptoms in adults with medial and/or lateral elbow epicondylitis (pain and tenderness on the inner and/or outer side of the elbow).
- Conditions
- Lateral Epicondylitis, Medial Epicondylitis, Obsessive-Compulsive Symptoms
- Trial name
- NCT07906379
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Fatih Turkmensoy
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Obsessive - Compulsive Disorder, Transcranial Magnetic Stimilation
Electrophysiological Biomarkers and Treatment Response to Accelerated Transcranial Magnetic Stimulation in Patients With Obsessive-Compulsive Disorder
Purpose: This study aims to evaluate the effectiveness of an accelerated intermittent Theta Burst Stimulation (iTBS) protocol-a non-invasive brain stimulation technique-targeted at the dorsomedial prefrontal cortex (dmPFC) and…
- Conditions
- Obsessive - Compulsive Disorder, Transcranial Magnetic Stimilation, Intermittent Theta Burst Stimulation, EEG
- Trial name
- TMS-OCD-EEG (NCT07561528)
- Testing
- iTBS TMS
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University - Cerrahpasa
Obsessive-Compulsive Disorder
Identifying Local Field Potential Biomarkers for Obsessive-compulsive Disorder Treatment With Deep Brain Stimulation
Obsessive-compulsive disorder (OCD) is a complex and severe mental illness characterized by multiple symptoms and is considered a leading cause of non-fatal health loss.
- Trial name
- DBS OCD (NCT06542224)
- Testing
- Deep Brain stimulation
- Where
- 4 sites in China
- Volunteers
- 16 people
- Sponsor
- West China Hospital
Obsessive Compulsive Disorder (OCD), Obsessive - Compulsive Disorder
Accelerated rTMS Therapeutic Approach for Refractory Obsessive-Compulsive Disorder
The goal of this clinical trial is to learn if individualized accelerated repetitive transcranial magnetic stimulation (rTMS) targeting the inferior frontal cortex combined with symptom provocation works to treat…
- Trial name
- OCDTMS-IFC (NCT07198594)
- Testing
- rTMS
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University
Obsessive-compulsive Disorder
Evaluation Study: Obsessive-compulsive Disorders in Childhood and Young Adulthood
Obsessive-compulsive disorders are very damaging illnesses that can already manifest in childhood and adolescence. With an average prevalence from 1 - 3%, they are one of the most frequently diagnosed psychiatric illness in these…
- Trial name
- NCT04723485
- Where
- Switzerland
- Volunteers
- 625 people
- Sponsor
- Susanne Walitza
Anxiety, Anxiety Acute
Anxiety Skills Study
The purposes of this study are: (1) to identify baseline predictors of relative success in cognitive, behavioral, and mindfulness-based treatments for anxiety, (2) explore who benefits from a brief, video-based skill training…
- Conditions
- Anxiety, Anxiety Acute, Anxiety Chronic, Anxiety and Mood Disorders
- Trial name
- NCT07774481
- Testing
- Cognitive therapy, Behavioral therapy, Mindfulness-based therapy
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Ohio State University
Obsessive-Compulsive Disorder
Project EMPOWER-OCD
This research study aims to adapt and evaluate the acceptability and effectiveness of Project EMPOWER-OCD for socioeconomically diverse caregivers of patients with OCD. Designed to reduce obstacles (e.g.
- Trial name
- NCT07158801
- Testing
- Project EMPOWER-OCD, Project CARE
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Obsessive-Compulsive Disorder
ITreatOCD: Predicting the Efficacy of Internet-based Cognitive Behavioral Therapy in Obsessive-compulsive Disorder
In the current study, the investigators will characterize obsessive-compulsive disorder (OCD) patients and healthy controls with a comprehensive clinical and neuroimaging assessment, focusing on the basic psychological processes…
- Trial name
- iTREATOCD (NCT05906069)
- Testing
- ICBT
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Pedro Morgado
Obsessive Compulsive Disorder
SONATA LIFU for OCD
The study tests ATTN201, an investigational non-invasive headband that delivers low-intensity focused ultrasound (LIFU) to the subthalamic nucleus (STN) as a treatment for obsessive-compulsive disorder (OCD).
- Trial name
- NCT07728994
- Testing
- Low Intensity Focused Ultrasound
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pennsylvania
Obsessive-Compulsive Disorder
Pharmaco(Epi)Genetic, Proteomic, and Microbiomic Study of Obsessive-Compulsive Disorder
The purpose of this study is to determine whether pharmaco(epi)genetic study predict selective serotonin reuptake inhibitor (SSRI) responsiveness in advance before the appearance of the drug effect until 4 months(16 weeks), 6…
- Trial name
- NCT02431845
- Testing
- SSRIs
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Severance Hospital
Major Depressive Disorder, Obsessive-Compulsive Disorder
Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness
Participants will receive Transcranial Magnetic Stimulation (TMS) at a random location in the left prefrontal cortex, excluding sites that are potentially unsafe.
- Conditions
- Major Depressive Disorder, Obsessive-Compulsive Disorder, Schizophrenia, Generalized Anxiety Disorder
- Trial name
- Expedition (NCT06376734)
- Testing
- Transcranial magnetic stimulation
- Where
- 2 sites in United States
- Volunteers
- 180 people
- Sponsor
- Brigham and Women's Hospital
Deep Brain Stimulation
Efficacy and Safety of Combo-stim Deep Brain Stimulation for Treatment-refractory Mental Disorders
This is a multi-center, single arm, prospective, open-label, extendable study for the efficacy and safety of combo-stim deep brain stimulation for treatment-refractory mental disorders (obsessive-compulsive disorder…
- Trial name
- NCT06112067
- Testing
- deep brain stimulation
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Shanghai Mental Health Center
Borderline Personality Disorder, Narcissism
Evaluation of a Dimensional Adaptation of Good Psychiatric Management (GPM-extended) for the Treatment of Borderline Personality Disorder
The goal of this clinical trial is to evaluate whether a dimensional adaptation of Good Psychiatric Management (called GPM-extended) is more effective than classic Good Psychiatric Management (GPM) in treating adult patients with…
- Conditions
- Borderline Personality Disorder, Narcissism, Obsessive Compulsive Personality Disorder, Personality Disorder
- Trial name
- EPSYLIA (NCT06913738)
- Testing
- GPM-Extended, Classic GPM
- Where
- 2 sites in France
- Volunteers
- 154 people
- Sponsor
- AddiPsy
Obsessive - Compulsive Disorder
tDCS and Symptom Provocation in Treatment-Resistant OCD
The goal of this clinical trial is to learn if symptom provocation before transcranial Direct Current Stimulation (tDCS) in Obsessive-Compulsive Disorder (OCD) patients.
- Trial name
- PPS-TDCSTOC (NCT07429500)
- Testing
- tDCS session, symptom provocation
- Where
- 6 sites in France
- Volunteers
- 178 people
- Sponsor
- Centre Hospitalier Henri Laborit
Obsessive-Compulsive Disorder (OCD)
Explore Neural Mechanism of Obsessive-Compulsive Disorder (OCD) by Intervention of Repetitive Transcranial Magnetic Stimulation With Symptom Provocation
The purpose of this study is to investigate the differences in therapeutic efficacy of different deep Transcranial Magnetic Stimulation (deep TMS) treatment coils and different brain stimulation targets on obsessive-compulsive…
- Trial name
- NCT07587112
- Where
- Taiwan
- Volunteers
- 96 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Panic Disorder, Social Anxiety Disorder
Evaluation of Primary Care Behavioral Health (PCBH) With the Addition of Self-help CBT - A Randomized Multicenter Trial
In this multicenter study, the investigators want to find out if an addition of an diagnostic assessment and possibility of treatment with guided self-help CBT can increase the treatment effects of PCBH on patient functioning and…
- Conditions
- Panic Disorder, Social Anxiety Disorder, Depression, Hypochondriasis
- Trial name
- KAIROS (NCT04900064)
- Testing
- Brief interventions, Self-help CBT
- Where
- 4 sites in Sweden
- Volunteers
- 1,242 people
- Sponsor
- Linnaeus University