Clinical trials: Obsessive-compulsive Disorder (OCD)
Obsessive-Compulsive Disorder
A Medication Trial Combined With Behavior Therapy for Individuals With Obsessive-compulsive Disorder
This study examines the efficacy of the medication D-Cycloserine in the reduction of obsessions and compulsions in individuals with obsessive-compulsive disorder (OCD).
- Trial name
- NCT00126282
- Testing
- behavior therapy, D-Cycloserine
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Obsessive-Compulsive Disorder
An eHealth Intervention for Obsessive Compulsive Disorder in Youth With Autism Spectrum Disorder
This study is a feasibility study of Internet-delivered CBT for OCD in children and adolescents (7-17 years) with comorbid Autism Spectrum Disorder.
- Trial name
- NCT03473080
- Testing
- Internet CBT
- Where
- Sweden
- Volunteers
- 22 people
- Sponsor
- Karolinska Institutet
Obsessive-compulsive Disorder
Brief Intervention for OCD Fears
The study will test the efficacy of propranolol or placebo, administered after reactivation of a previously acquired obsessive-compulsive disorder (OCD) fear, in reducing fear and avoidance in OCD.
- Trial name
- NCT02790710
- Testing
- Propanolol
- Where
- United States
- Sponsor
- New York State Psychiatric Institute
Obsessive Compulsive Disorder
A Randomized, Double-Blind, Placebo-Controlled Trial of Flumazenil for the Treatment of Obsessive Compulsive Disorder
The purpose of this study is to evaluate the efficacy of flumazenil in the outpatient treatment of Obsessive Compulsive Disorder (OCD).
- Trial name
- OCD (NCT00997087)
- Testing
- Flumazenil
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Parkway Medical Center
Obsessive-compulsive Disorder
Clinical Outcomes in Pediatric Obsessive-Compulsive Disorder
Obsessive-Compulsive Disorder (OCD) is a common neuropsychiatric illness beginning in childhood. Effective OCD treatments include cognitive-behaviour therapy (CBT) and medications but access to treatment is difficult and does not…
- Trial name
- NCT01635569
- Testing
- Group-based family cognitive-behavioural therapy, Waitlist
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- University of British Columbia
Aneurysms, Arteriovenous Malformations
Neurosurgical Outcome Network
The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared.
- Conditions
- Aneurysms, Arteriovenous Malformations, Cavernomas, Skull Base Tumors
- Trial name
- NEON (NCT06724029)
- Where
- 27 sites in Italy
- Volunteers
- 4,500 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Obsessive - Compulsive Disorder
Clinical and Biological Correlates of Obsessive-Compulsive Disorder and Online Mindfulness-Based Cognitive Therapy
The study has two main objectives: (1) to evaluate the acceptability and feasibility of a specialized Mindfulness-Based Cognitive Therapy (MBCT) program for Obsessive-Compulsive Disorder (OCD), delivered via videoconference in a…
- Trial name
- MIND-DOC (NCT07834567)
- Testing
- Mindfulness-based Cognitive Therapy for OCD
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Obsessive-Compulsive Disorder (OCD)
Explore Neural Mechanism of Obsessive-Compulsive Disorder (OCD) by Intervention of Repetitive Transcranial Magnetic Stimulation With Symptom Provocation
The purpose of this study is to investigate the differences in therapeutic efficacy of different deep Transcranial Magnetic Stimulation (deep TMS) treatment coils and different brain stimulation targets on obsessive-compulsive…
- Trial name
- NCT07587112
- Where
- Taiwan
- Volunteers
- 96 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
OCD, Obsessive-Compulsive Disorder
Discovering Factors in the Clinical Study Journey of Patients With OCD
This research aims to collect comprehensive data on the clinical trial experience of OCD patients. Its goal is to identify the factors that limit patients' ability to join or complete a trial successfully.
- Trial name
- NCT05881356
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Obsessive-Compulsive Disorder
Smart Sensory Technology in Psychotherapy for Pediatric OCD
Telemedicine interventions enable the improvement of behavioral state-of-the-art treatment of OCD, as therapy can be delivered in the patients' immediate home environment, allowing for more valid symptom actualization.
- Trial name
- SSTeP-KiZ (NCT05291611)
- Testing
- Online-based Cognitive-behavioral Therapy for OCD
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Tuebingen
Trichotillomania
Technology Assisted Treatment of Trichotillomania: Open Trial
This open-label feasibility trial evaluates the use of the Keen2 awareness bracelet for adults with trichotillomania (hair-pulling disorder). Participants will use the bracelet for eight weeks.
- Trial name
- NCT07224126
- Testing
- Keen2 Predictive Awareness Bracelet
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- HabitAware Inc.
Obsessive-Compulsive Disorder
Transcranial Direct Current Stimulation (tDCS) for Treatment-Resistant Obsessive-Compulsive Disorder (FRONT)
Neuromodulation techniques for the treatment of Obsessive-Compulsive Disorder (OCD) have expanded with the greater understanding of the brain circuits involved in this disorder.
- Trial name
- FRONT (NCT02743715)
- Testing
- Active tDCS (transcranial direct current stimulation)
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- University of Sao Paulo
Obsessive Compulsive Disorder
rTMS in Treatment of Obsessive Compulsive Disorder (OCD)
Low frequency (1Hz) rTMS applied bilaterally and simultaneously over SMA for 6 weeks in addition to the standard treatment regimen for OCD, will lead to significant improvement in patients' symptoms.
- Trial name
- NCT00616486
- Testing
- repetitive transcranial magnetic stimulation
- Where
- 3 sites in Bulgaria, Canada and 1 more
- Volunteers
- 24 people
- Sponsor
- Queen's University
Obsessive-Compulsive Disorder
Initial Development and Dissemination of OC-Go
The clinical component of Phase I application development examines the clinical utility, feasibility, and functionality of the OC-Go application via an 8-month pilot trial consisting of 50 standard CBT sessions augmented with…
- Trial name
- OC-GoPhaseI (NCT03126305)
- Testing
- OC-Go
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of California, Los Angeles
Anxiety Disorders, Mood Disorders
Efficacy Evaluation of a Unified Transdiagnostic Treatment for Anxiety Disorders
Anxiety disorders are common, chronic, costly, debilitating to quality of life, and are more prevalent than any other class of disorders in every country in the world where surveys have been taken.
- Trial name
- NCT01243606
- Testing
- Single Diagnosis Treatment Protocol, Unified Protocol (UP)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Boston University Charles River Campus
Obsessive-Compulsive Disorder
Pilot Study of Ketamine in Adults With Obsessive-Compulsive Disorder (OCD)
In this study investigators are studying the effects of a drug called ketamine on the symptoms of Obsessive-compulsive disorder (OCD).
- Trial name
- NCT01100255
- Testing
- Ketamine infusion, Saline
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- New York State Psychiatric Institute
Hoarding Disorder, Hoarding
Detection of Hoarding Disorder and Related Psychopathology
Hoarding disorder is characterized by excessive amassment of objects in the home and difficulty of getting rid of the objects. It is associated with a high level of somatic and psychiatric comorbidity, suicidality, social…
- Trial name
- NCT07483021
- Testing
- Assertive and supportive diagnostic detection team
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Andreas Rosén Rasmussen
Obsessive-Compulsive Disorder
Imaging-Guided Low Intensity Focused Ultrasound (LIFU)
This research study is to investigate the safety, feasibility, and possible therapeutic benefits of a technology called Low Intensity Focused Ultrasound (LIFU) in patients with obsessive- compulsive disorder (OCD).
- Trial name
- LIFU (NCT05467085)
- Testing
- BX Pulsar 1002
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Baylor College of Medicine
Trichotillomania (Hair-Pulling Disorder)
Efficacy of Valbenazine for the Treatment of Trichotillomania in Adults
This trial aims to evaluate the efficacy, safety and tolerability of valbenazine, titrated to the subject's optimal dose of 40mg or 80mg, administered once daily, for 12 weeks, for the treatment of trichotillomania (TTM) in a…
- Trial name
- NCT05207085
- Testing
- Valbenazine Oral Capsule
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Yale University
Obsessive Compulsive Disorder
Using Drug Augmentation to Treat Obsessive Compulsive Disorder Patients Who Did Not Respond to Previous Treatment
This will be a controlled, randomized, double-blind and double-dummy study on the treatment augmentation strategy for obsessive compulsive disorder patients non-respondent to first line pharmacological treatment.
- Trial name
- EPMTOC (NCT00466609)
- Testing
- Clomipramine (fluoxetine plus clomipramine), Quetiapine (fluoxetine plus quetiapine)
- Where
- Brazil
- Volunteers
- 54 people
- Sponsor
- University of Sao Paulo