Clinical trials: Obsessive-compulsive Disorders and Symptoms in Children
Mental Disorders, Severe
Measuring Development of Brain Responses to Vocal Sounds in Babies of Mums With Mental Illness
CAPRI-Voc examines the differences in how speech and environmental sounds are processed in the infant brain as they grow from 9 to 12 months.
- Trial name
- CAPRI-Voc (NCT04350294)
- Where
- United Kingdom
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Behavioral Activation, Major Depressive Disorder
Pharmacogenomics of Selective Serotonin Reuptake Inhibitor (SSRI)-Induced Behavioural Activation
The purpose of this study is to identify and validate a panel of genetic markers associated with selective serotonin reuptake inhibitors (SSRI)-induced behavioural activation in children and youth with major depressive disorder…
- Conditions
- Behavioral Activation, Major Depressive Disorder, Anxiety Disorders, Antidepressant Drug Adverse Reaction
- Trial name
- PGx-SImBA (NCT06763081)
- Testing
- Not applicable- observational study
- Where
- 2 sites in Canada
- Volunteers
- 160 people
- Sponsor
- University of Manitoba
Obsessive-compulsive Disorders and Symptoms in Children
Task Control Circuit Targets for Obsessive Compulsive Behaviors in Children
This study will use magnetic resonance imaging (MRI) to assess the function and structure of overlapping task control circuits in children with a range of Obsessive-Compulsive symptoms (OCS).
- Trial name
- NCT03584945
- Testing
- Cognitive Behavioral Therapy, Community Referral as appropriate
- Where
- 2 sites in United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Obsessive-Compulsive Disorder, Obsessive-Compulsive Disorder in Children
SPACE: a Parent-based Treatment for Pediatric OCD
This study will investigate the parent-based treatment SPACE: Supportive Parenting for Anxious Childhood Emotions. The aim of this study is to investigate whether SPACE is effective in reducing family accommodation (FA) and OCD…
- Conditions
- Obsessive-Compulsive Disorder, Obsessive-Compulsive Disorder in Children, Obsessive-Compulsive Disorder in Adolescence, Anxiety Disorders and Symptoms
- Trial name
- NCT06356090
- Testing
- Supportive Parenting for Anxious Childhood Emotions (SPACE)
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- Chaim Huijser
Prader Willi Syndrome, Obsessive-compulsive Disorder
Behavioral Treatment of Obsessive-Compulsive Symptoms in Youth With Prader-Willi Syndrome: A Pilot Project
Obsessive-compulsive (OC) symptoms are often present among youth with Prader-Willi Syndrome (PWS). They are also associated with considerable problems in the daily functioning of the child and his/her family.
- Trial name
- NCT00742664
- Testing
- Cognitive-behavioral therapy, Wait-list control
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of South Florida
Anxiety Disorders, Depressive Disorders
Antidepressant Safety in Kids Study
This study will evaluate the risks and benefits of treatment with a selective serotonin reuptake inhibitor or serotonin-norepinephrine reuptake inhibitor in children and adolescents with a pre-specified anxiety disorder…
- Conditions
- Anxiety Disorders, Depressive Disorders, Eating Disorders, Obsessive Compulsive Disorder
- Trial name
- ASK (NCT00395213)
- Testing
- Selective serotonin reuptake inhibitor (SSRI) and serotonin-norepinephrine reuptake inhibitor (SNRI) medications
- Where
- United States
- Volunteers
- 569 people
- Sponsor
- Duke University
Mindfulness Skills, Psychosocial Education
Mindfulness Intervention for Psychological and Family Dynamics in Children With Body-Focused Repetitive Behaviors
This is a single-center, randomized, controlled intervention study designed to evaluate the effectiveness of mindfulness intervention on reducing body-focused repetitive behaviors (BFRBs) in children aged 8-18, such as…
- Trial name
- MIND-BFRB (NCT06777212)
- Testing
- Mindfulness Training Program, Psychosocial Education Program
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Children's Hospital of Fudan University
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Tourette Syndrome, Obsessive Compulsive Disorder
Developmental Phenomenology of Obsessive Compulsive Disorder and Tourette Syndrome in Children and Adolescents
OBJECTIVES: I. Characterize the natural history, associated features, and severity of symptoms of obsessive compulsive disorder and Tourette syndrome in children and adolescents. II.
- Trial name
- NCT00004324
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Center for Research Resources (NCRR)
High Risk, Depression / Major Depressive Disorder
Tracking Risk in Adolescents and Children for Early Identification of Common Mental Disorders
This prospective observational cohort study will enroll approximately 200 children and adolescents aged 7-17 years who are at elevated risk for common mental disorders, including depressive disorders, anxiety disorders, and…
- Conditions
- High Risk, Depression / Major Depressive Disorder, Anxiety Disease, Obsessive - Compulsive Disorder
- Trial name
- TRACE (NCT07744490)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Mental Health Center
Dystonia, Epilepsy in Children
A Multicenter Pediatric Deep Brain Stimulation Registry
There is limited data on outcomes for children who have undergone deep brain stimulation (DBS) for movement disorders, and individual centers performing this surgery often lack sufficient cases to power research studies…
- Conditions
- Dystonia, Epilepsy in Children, Cerebral Palsy, Tourette Syndrome
- Trial name
- DBS-R (NCT06585618)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston Children's Hospital
Obsessive-compulsive Disorder, Social Phobia
Brief Behavioral Treatment for Anxiety in Young Children
Behaviorally and cognitive-behaviorally based therapeutic techniques (BT; CBT) that incorporate exposure therapy useful for treatment of anxiety disorders among typically developing children.
- Conditions
- Obsessive-compulsive Disorder, Social Phobia, Generalized Anxiety Disorder, Specific Phobia
- Trial name
- PLET (NCT02051192)
- Testing
- Parent-Led Exposure Therapy, Treatment As Usual
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of South Florida
Obsessive-Compulsive Disorder, Pediatric Psychiatric Disorder
Adjunctive Celecoxib in Childhood-onset OCD Study
This is a randomized, controlled, single-centre phase II superiority trial to determine the efficacy of 12 weeks of celecoxib (50 mg or 100 mg orally twice daily, dosed based on weight) compared to placebo as an adjunct to…
- Trial name
- ACE-OCD (NCT04673578)
- Testing
- Celecoxib
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of British Columbia
Schizophrenia Disorders, Personality Disorders
Recovery in Telling Life Stories
This project tests the Recovery In Telling Life Stories (RETELL) intervention, aimed at supporting personal recovery in people with severe mental illness (SMI).
- Conditions
- Schizophrenia Disorders, Personality Disorders, Obsessive - Compulsive Disorder, Anxiety Disorders
- Trial name
- RETELL (NCT07082777)
- Testing
- Narrative therapy
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Tourette's Disorder
Omega-3 Fatty Acids in Tourette's Disorder
This study examines the safety and efficacy of omega-3 fatty acids (fish oil) for the treatment of Tourette's Disorder.
- Trial name
- NCT01315327
- Testing
- Omega-3 Fatty Acids, Olive oil
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- NYU Langone Health
Anxiety Disorders, Depression
Pharmacogenomics of Antidepressant Response in Children and Adolescents
This study will identify variations in genes that may be involved in the development of suicidal events or certain behaviors in youth who are exposed to antidepressant medications.
- Conditions
- Anxiety Disorders, Depression, Eating Disorders, Obsessive-Compulsive Disorder
- Trial name
- PARCA (NCT00516932)
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- Duke University
Anorexia Nervosa
Obsessive-compulsive Symptoms in Children and Adolescents With Anorexia Nervosa
The purpose of this study is to determine obsessive-compulsive symptoms and BMI changes in children and adolescents with anorexia nervosa and find out whether there is a group-level correlation between the two.
- Trial name
- NCT04770662
- Testing
- Questionnaires
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- Universitair Ziekenhuis Brussel