Clinical trials: Obstetric Anesthesia
Obstetric Anesthesia Problems
Leader and Team Performance During PPH Simulated Scenario
The primary aim of this study is the progress of the performance of the leader and of the team for the postpartum hemorrhage (PPH) before and after four high-fidelity standardized scenarios of severe PPH (1500 mL blood loss) due…
- Trial name
- NCT04398602
- Testing
- behavior of the leader
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Capogna Giorgio
Indication for Care or Intervention Related to Labor or Delivery With Baby Delivered
Incidence of Difficult Airway and Difficult Neuraxial Placement in Obstetric Patients
Anesthesiologists commonly administer pain relief during labor or providing anesthesia for cesarean delivery. Two main methods are used to achieve these goal: "Regional anesthesia" where the mother is given medication through a…
- Trial name
- DADB (NCT02193542)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Cesarean Delivery, General Anesthesia
The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry
The SOAP registry is a prospective, multicenter, electronic registry. The goal is to investigate the indications, mode of airway management, predisposing factors, and obstetric and anesthetic outcomes of pregnant patients who…
- Trial name
- NCT06030063
- Where
- 35 sites in United States, Canada
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Yale University
Drying Time
Chlorhexidine Drying Time
Before a patient gets a spinal/epidural, their lower back is cleaned with an antiseptic solution diluted in alcohol called ChloraPrep. ChloraPrep must completely dry before starting the anesthetic procedure.
- Trial name
- Chlorhexidine (NCT02095535)
- Testing
- Chlorhexidine gluconate
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Twin Pregnancy, Neonate
Neonatal Outcomes in Twin Pregnancies
Multiple pregnancies are associated with increased maternal and fetal risks compared to singleton pregnancies. Additionally, the cesarean section rate is quite high in multiple pregnancies.
- Trial name
- NCT05104255
- Testing
- Spinal anesthesia, General anesthesia
- Volunteers
- 527 people, healthy volunteers welcome
- Sponsor
- Derince Training and Research Hospital
Obstetric
Analgesic Efficacy of Transvers Abdominis Plane Block and Transversalis Fascia Plane Block in Cesarean Section
This study was designed as a prospective, randomized observational clinical trial. A total of 90 adult women were included in the study performed elective cesarean section.
- Trial name
- NCT06386978
- Testing
- Transverse Facia Plane Block (TAP Block), Transversalis Facia Plane Block (TFP Block), Control
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Quality of Life, Obstetric Complication
Evaluation of the Relationship Between Obstetric Comorbidity Index and Obstetric Quality of Recovery Score
The goal of this prospective observational study is to learn about the correlation between obstetric comorbidity index and obstetric quality of recovery score in pregnant patients who undergo cesarean section.
- Conditions
- Quality of Life, Obstetric Complication, Cesarean Section Complications, Comorbidities and Coexisting Conditions
- Trial name
- NCT05704179
- Testing
- Obstetric Quality of recovery score
- Where
- Turkey (Türkiye)
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Anesthesia; Sexual, Analgesia
The Effect of Peripheral Nerve Blocks on Postoperative Analgesia in Elective Cesarean Section
The goal of this prospective randomized study was to compare the efficacy of transversus abdominis plane block and transversalis fascia plane block for postoperative analgesia in patients undergoing elective cesarean section…
- Trial name
- NCT05758233
- Testing
- Patients undergoing transversalis fascia plane block, Patients undergoing transversus abdominis plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Obstetric Anesthesia Problems, Placenta Accreta
Fibrinogen Concentrate and Placenta Acreta Spectrum
The aim of this study is to evaluate the relationship between fibrinogen use and bleeding in patients who underwent cesarean section with a prediagnosis of PAS.
- Trial name
- NCT05938062
- Testing
- the group without fibrinogen concentrate (GNF) , the group with fibrinogen concentrate (GF)
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Postpartum Hemorrhage
Carbetocin Versus Ergometrin in the Prevention of Postpartum Hemorrhage
In the present study will be compared Carbetocin with ergometrin in the prevention of postpartum haemorrhage (PPH) in parturients that are undergoing caesarean section and are not presenting risk factors for PPH.
- Trial name
- NCT04300452
- Testing
- Carbetocin, Ergometrine Maleate
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Obstetric Pain, Postpartum Depression
Ketamine to Improve Recovery After Cesarean Delivery - Part 1
The objective of this study is evaluate the breastmilk transfer and pharmacokinetics (Part 1) and effectiveness (Part 2) of a post-cesarean delivery intravenous ketamine bolus-and-infusion strategy, as a preventive analgesic…
- Conditions
- Obstetric Pain, Postpartum Depression, Breastfeeding, Pain, Acute
- Trial name
- KINETIC (NCT04037085)
- Testing
- Ketamine
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Gastric Ultrasound, Fasting ( 6H for Solid ; 2H for Clear Fluid )
Ultrasound Assessment of Gastric Content in Fasted Pregnant Women
Pulmonary aspiration of gastric content is one of the most feared perioperative complication of general anesthesia. Pregnant women are usually considered as high risk of pulmonary aspiration but there is no epidemiological study…
- Conditions
- Gastric Ultrasound, Fasting ( 6H for Solid ; 2H for Clear Fluid ), Pregnant Women
- Trial name
- ECHOmater (NCT04277013)
- Where
- France
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Labour Pain
Combined Spinal-Epidural Versus Traditional Labor Epidural
The purpose of this study to compare the use of spinal-epidural versus traditional labor epidural on maternal and fetal effects.
- Trial name
- NCT00151346
- Testing
- Bupivacaine and Fentanyl (for CSE), Bupivacaine and Fentanyl (for traditional epidural)
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Pregnancy, Labor Pain
Does Ultrasound of the Spine Improve Labor Epidurals/Spinal Anesthesia in Obstetric Patients?
The investigators are interested in determining the utility of ultrasound of the spine for labor epidurals or spinal anesthesia for women in labor or having a cesarean delivery.
- Trial name
- NCT01243216
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Postdural Puncture Headache, Regional Anesthesia Morbidity
Postdural Punction Headache After Ceserian Section
The aim of this study is to compare the effect of spinal needle type on postdural puncture headache in patients who will undergo cesarean section.
- Conditions
- Postdural Puncture Headache, Regional Anesthesia Morbidity, Pregnancy Related
- Trial name
- NCT05777694
- Testing
- Patients who underwent cesarean section under spinal anesthesia with 25 gauge spinal needle, Patients who underwent cesarean section under spinal anesthesia with 26 gauge spinal needle, Patients who underwent cesarean section operation under spinal anesthesia with 27 gauge spinal needle
- Where
- Turkey (Türkiye)
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Obstetric Anesthesia, Cardiac Monitoring
Cardiac Output Changes With Uterine Displacement
There is currently little information regarding the hemodynamic differences in uterine displacement techniques. Previous studies examining the hemodynamic effects of uterine displacement maneuvers have focused on incidence of…
- Trial name
- LUDCO (NCT02283931)
- Testing
- TTE / NICOM
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Post-Surgical Complication
Comparsion of IV Dexmedetomidine, Tramdol and Ketamine for Post Spinal Anesthesia Shivering.
To study control of post spinal shivering in patients undergoing lower segment cesarean section using dexmedetomidine, tramadol and ketamine
- Trial name
- NCT05311722
- Testing
- Dexmedetomidine, Ketamine, Tramadol
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Sheikh Zayed Medical College
Obstetric Anesthesia Problems
Preloading to Prevent Hypotension During Cesarean Section
Whether the usage of non-invasive arterial blood pressure monitor to guide fluid therapy in caesarean section can effectively reduce the incidence of hypotension and fetal complications.
- Trial name
- NCT03013140
- Testing
- Fluid therapy, Spinal anaesthesia
- Where
- Taiwan
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Labor, Obstetric
Nutrition as a Determinant of Labor Outcome
This is a randomized, double-blind trial looking at how nutrition intake is associated with labor progress and complications.
- Trial name
- NCT00367549
- Testing
- Energy-containing soft drink
- Where
- Norway
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Epidural, Labor Pain
Improving Labour Induction Analgesia: Epidural Fentanyl Bolus at Epidural Initiation for Induction of Labour
Labour pain can be intensified for labour inductions and women undergoing inductions often have earlier and more frequent requests for analgesia.
- Conditions
- Epidural, Labor Pain, Induction of Labor Affected Fetus / Newborn, Obstetric Anesthesia Problems
- Trial name
- NCT04011098
- Testing
- Epidural Fentanyl Bolus, Standard Epidural Group
- Where
- Canada
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan