Clinical trials: Obstetric Bleeding
Intraventricular Hemorrhage of Prematurity, Nursing Caries
Effectiveness of Nursing Care Bundle for the Prevention of Intraventricular Hemorrhage in Preterm Infants
Existing measures to prevent intraventricular hemorrhage in preterm infants include preventing premature delivery, pre-natal administration of corticosteroid, active treatment of chorioamnionitis, and improvement of postnatal…
- Trial name
- NCT05844709
- Testing
- IVH care Bundle
- Where
- Taiwan
- Volunteers
- 178 people
- Sponsor
- National Taiwan University Hospital
Obstetric Labor Complications, Hemorrhage
Thromboelastometry-guided Treatment Protocol Versus Standard Care of Major Haemorrhage in Obstetric Patients
This is a prospective, randomized and controlled study to find out if a rotational thromboelastometry(ROTEM) guided treatment protocol reduces the need for blood transfusions in major obstetric haemorrhage compared to standard…
- Trial name
- ROTEM-PPH (NCT02461251)
- Testing
- Rotational Thromboelastometry (ROTEM)
- Where
- Finland
- Volunteers
- 59 people
- Sponsor
- Tampere University Hospital
Post Partum Hemorrhage, Fibrinogenolysis; Hemorrhage
Patient Blood Management for Massive Obstetric Hemorrhage
Obstetric Hemorrhage continues to be the first cause of maternal morbidity and mortality around the world especially in middle to low income countriesThe blood components are high value resources; however, its use has been shown…
- Conditions
- Post Partum Hemorrhage, Fibrinogenolysis; Hemorrhage, Fibrinogen; Deficiency, Acquired, Massive Hemorrhage
- Trial name
- NCT03784794
- Testing
- Thromboelastometry, Standard Coagulation Test, Fibrinogen Concentrate Human
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Angel Augusto Perez Calatayud
Placenta Previa
Vaginal Progesterone Versus 17-Alpha-Hydroxyprogesterone Caproate in Placenta Previa
Purpose to evaluate the effects of Vaginal Progesterone versus 17-Alpha-Hydroxyprogesterone Caproate for prevention of Emergent Cesarean Delivery in Asymptomatic Pregnant Women with Placenta Previa
- Trial name
- NCT03779451
- Testing
- 17-OHPC, vaginal progesterone
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Aswan University Hospital
Postpartum Hemorrhage
Carbetocin Versus Misoprostol in Cases With Placenta Previa After C.S.
We will compare efficacy and safety of Carbetocin with Misoprostol in prevention of postpartum hemorrhage in Placenta previa women after C.S.
- Trial name
- PPH (NCT02277041)
- Testing
- Carbetocin, Misoprostol
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Beni-Suef University
Placenta Previa
Vaginal Progesterone Against a Second Attack of Antepartum Haemorrhage in Placenta Previa Women
Placenta praevia is associated with an increased risk of preterm delivery (PTD) especially if associated with bleeding and uterine contractions .
- Trial name
- NCT04725929
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Nourhan Ashraf ElSherbiny
Postpartum Period
Evaluation of Blood Loss After Cesarean Delivery Via US Compared to Standard Care
Postpartum hemorrhage and anemia are considered a major health concern due to their impact on maternal morbidity and mortality, quality of life, and maternal cognitive and emotional functioning after delivery, which are…
- Trial name
- NCT06963047
- Testing
- Ultrasound, Standard care
- Where
- Israel
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Holy Family Hospital, Nazareth, Israel
Postpartum Hemorrhage
Comparative Study Between the Roles of Intrauterine Misoprostol Versus the Sublingual Route for Prevention of Postpartum Blood Loss in Elective Cesarean Sections
Study design: A prospective randomized control trial was carried out at labor and delivery unit at Kasr Al Aini Hospital, Cairo University.
- Trial name
- NCT06364098
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Cairo University
Intraventricular Hemorrhage, Premature Birth
Intranasal Fresh Mother's Own Milk to Prevent Intraventricular Hemorrhage in Extremely Preterm Infants
Babies born very prematurely are at risk of intraventricular hemorrhage (IVH), which is bleeding in or around the fluid-filled spaces of the brain. Most IVH occurs during the first week after birth.
- Trial name
- iF-MOM-IVH (NCT07812922)
- Testing
- Intranasal Fresh Mother's Own Milk (iF-MOM)
- Volunteers
- 67 people
- Sponsor
- University of Manitoba
Cesarean Section Complications, Intrapartum Hemorrhage
A Novel Technique Of Uterine Cooling During Repeated Cesarean Section For Reducing Blood Loss
Study aim to evaluate the efficacy and safety of a novel technique of UTERINE COOLING during repeated cesarean section (CS) in reducing blood loss, and record any adverse effects following it.
- Conditions
- Cesarean Section Complications, Intrapartum Hemorrhage, Postpartum Hemorrhage, Atony, Uterine
- Trial name
- NCT03793153
- Testing
- Uterine Cooling Technique
- Where
- Egypt
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Hemorrhage, Premature Infants
NIRS Monitoring in Premature Infants
This study uses frequency domain near-infrared spectroscopy coupled with diffuse correlation spectroscopy (FDNIRS-DCS) technology for monitoring cerebral blood flow (CBF) and cerebral oxygen metabolism (CMRO2) at the bedside for…
- Conditions
- Hemorrhage, Premature Infants, Newborn, Hydrocephalus
- Trial name
- NCT02601339
- Testing
- ETV/CPC
- Where
- 3 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Postpartum Hemorrhage
Comparing Misoprostol and Oxytocin in Uniject for Postpartum Hemorrhage (PPH) Prevention in Senegal
This is a large, community-based, cluster-randomized trial to compare routine prophylactic use of 600 mcg oral misoprostol and 10 IU oxytocin delivered by UnijectTM intramuscularly during the third stage of labor
- Trial name
- NCT01713153
- Testing
- Misoprostol, UnijectTM
- Where
- Senegal
- Volunteers
- 1,365 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Placental Expulsion Time
Influence of Acupuncture in the Placental Expulsion Time
In this study, a single blind randomized trial is carried out in order to compare placental detachment times when Ren Mai 6 is stimulated and when a different placebo point is used.
- Trial name
- NCT02000752
- Testing
- Acupuncture
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Principe de Asturias
Perinatal Outcomes
Can Safety Planning Improve Perinatal Outcomes Among Pregnant Women Exposed to Intimate Partner Violence?
OBJECTIVE: To investigate if, among women exposed to physical violence during pregnancy, does a targeted intervention consisting of safety planning and referral to community advocacy services decrease rates of adverse perinatal…
- Trial name
- NCT00831831
- Testing
- Safety planning
- Where
- Canada
- Sponsor
- University of British Columbia
Postpartum Hemorrhage
Misoprostol for Treatment of Postpartum Hemorrhage at Community-level Births in Egypt
This randomized controlled community-based trial will assess the effectiveness of administration of 800 mcg sublingual misoprostol with standard of care vs.
- Trial name
- NCT01619072
- Testing
- Misoprostol + referral
- Where
- Egypt
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Postpartum Hemorrhage, Uterine Atony
Does Intramyometrial Oxytocin Improve Outcome in Elective Cesarean Delivery?
Oxytocin use has become routine practice in elective cesarean delivery to promote uterine contraction and reduce blood loss. However, there is a lack of consensus regarding the best dose of oxytocin and the most effective route…
- Trial name
- NCT01252342
- Testing
- Oxytocin, Saline
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Cesarean Section Complications
Reducing Blood Loss During Cesarean Hysterectomy for Placenta Accreta Spectrum
PAS is an obstetrics condition that is closely linked with massive obstetrical hemorrhage with a varied incidence about once in every 533 live births.
- Trial name
- NCT03570710
- Testing
- intravenous tranexamic acid, Topical tranexamic acid, Normal saline
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Aswan University Hospital
Massive Transfusion, Trauma
Australian and New Zealand Massive Transfusion Registry
Severe and un-stopped blood loss can occur for a number of different reasons including after a serious injury, delivery of a baby and following other medical and surgical emergencies.
- Conditions
- Massive Transfusion, Trauma, Cardiothoracic Surgery, Gastrointestinal Bleeding
- Trial name
- ANZ-MTR (NCT02863250)
- Where
- Australia
- Volunteers
- 50,000 people
- Sponsor
- Monash University
Placenta Previa, Post Partum Hemorrhage
Glove-loaded Foley's Catheter Tamponade for Cesarean Section for Placenta Previa
Objective: To investigate the effect of A glove-loaded Foley's catheter tamponade versus stepwise uterine devascularization on blood loss during cesarean section (CS) in patients with complete placenta previa.
- Trial name
- NCT03570723
- Testing
- A glove-loaded Foley's catheter tamponade, stepwise uterine devascularization
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Aswan University Hospital
Premature Infants
Urine Concentration of S100B in Extremely Premature Infants
S100B, a calcium-binding protein, is found predominantly in the central nervous system (CNS) and is increased in CSF and blood after CNS injury. There are two objectives to this study.
- Trial name
- NCT00747591
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Utah