Clinical trials: Obstetric Pain
Neonatal Pain, Retinopathy of Prematurity (ROP)
Fentanyl Intranasal for Retinopathy of Prematurity Screening in Preterm Infants
The goal of this clinical trial is to learn whether intranasal fentanyl (a pain medicine given as a nasal spray) can reduce pain and is safe to use during routine eye examinations for retinopathy of prematurity (ROP) in preterm…
- Conditions
- Neonatal Pain, Retinopathy of Prematurity (ROP), Pain Management, Infant, Premature
- Trial name
- FIREFLY (NCT07112430)
- Testing
- Fentanyl Citrate (Intranasal)
- Where
- Canada
- Volunteers
- 58 people
- Sponsor
- Marsha Campbell-Yeo
Getting Pregnant, Labor Pain
Sacral Pressure During Labor: Effects on Pain and Maternal Satisfaction
The study will be conducted with pregnant women in the active and transitional phases of labor. In the intervention group, sacral pressure will be applied during contractions, while the control group will receive routine clinical…
- Conditions
- Getting Pregnant, Labor Pain, Intrapartum Period, 37-42 Weeks of Gestation
- Trial name
- NCT07371039
- Testing
- manual pressure application
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir Kavram Vocational School
Labor Pain
Tetracaine Combined Spinal Epidural (CSE) Versus Bupivacaine CSE
The investigators hypothesis is that spinal tetracaine with fentanyl and epinephrine used for CSE labor analgesia volume will last a significantly longer period of time that that of spinal bupivacaine with fentanyl.
- Trial name
- NCT01005459
- Testing
- Tetracaine, Bupivacaine
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Wake Forest University
Postoperative Pain
Postoperative Pain in Infants
This observational study aims to evaluate skin conductance measurement (SCM) for pain assessment in postoperative newborns. Pain assessment in newborns is challenging due to their inability to communicate, and current methods…
- Trial name
- Poppi (NCT07856615)
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Uppsala University Hospital
Labor Pain, Labor
The Effect of Pregnant-controlled Sacral Massage on Mothers' Labor Pain, Perception, Process and Midwives' Satisfaction
Our study aims to determine the effect of pregnant-controlled automatic sacral massage on mothers' labor pain, perception, process and midwives' satisfaction.
- Trial name
- NCT06499402
- Testing
- massage
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Osmaniye Korkut Ata University
Parturients
Study to Determine Whether the Instillation of 10ml Normal Saline Improves Epidural Analgesia During Labor
In current obstetric anesthesia practice, epidural analgesia is the most effective technique to control labor pain for those women who request pain-free delivery.
- Trial name
- NCT01119079
- Testing
- Normal Saline, Administration of epidural anesthesia for labor
- Where
- United States
- Sponsor
- University of Medicine and Dentistry of New Jersey
Pregnancy
The Physical Effects of Pain Catastrophizing in Labor
The purpose of this study is to determine whether labor self-efficacy (as determined by scores for the Lederman PSEQ II (self-efficacy scores) impacts the second stage 2 length (nromal vs.
- Trial name
- NCT01012466
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Obstetric Pain
Bupivacaine Verus Pethidine for Post Cesarean Section Pain Relief
The aim of this study is to compare between the effect of wound infiltration with bupivacaine or pethidine for post cesarean section pain relief.
- Trial name
- NCT03652116
- Testing
- Wound infiltration by Bupivacaine, Wound infiltration by Pethidine
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Ain Shams University
Labor Pain
Comparative Study of the Loading Dose Administrated Via Epidural Needle or Epidural Catheter for Labor Analgesia
Epidural anesthesia (EP) is widely used for labor analgesia. Time to onset of adequate pain relief of EP technique for labor analgesia may be 15 to 20 minutes.More rapid injection is often passible through the needle compared to…
- Trial name
- NCT05594771
- Testing
- epidural needle, epidural catheter
- Where
- China
- Volunteers
- 276 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Cesarean Delivery
An Observational Study Measuring in a Non-invasive Approach the Nociception Level Index and Its Association With Pain and Anxieiy Perception Evaluated by Questionnaires, in Awake Women During Elective Cesarean Delivery Under Spinal Anesthesiaanxiety
The Nociception Level (NOL) Index is a multiparametric, non-invasive monitor that objectively assesses nociception by integrating several autonomic physiological signals.
- Trial name
- NCT07726316
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Michael Grach
Labor Pain
Study of the Effectiveness of Administration of Meperidine on the Length of Active Phase of Labor in Women
This study aims to evaluate the effect of meperidine on the length of active phase of labor in nulliparous or multiparous women, who will be randomized into two (control and study) groups.
- Trial name
- NCT01555671
- Testing
- Meperidine, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Labor Pain, Epidural Analgesia
Epidural vs. Dural Puncture Epidural in Labor Analgesia
Childbirth is an intense physical and psychological experience. Epidural analgesia (EP) remains the gold standard in labor pain management.
- Trial name
- NCT06849726
- Testing
- Standard Epidural Analgesia, Dural Puncture Epidural Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Medipol University
Analgesia, Labor Pain
Effect of Epidural Hydromorphone Combined With Ropivacaine in Labor Analgesia
The purpose of this study is to compare the effects of three different doses of hydromorphone combined with ropivacaine and sufentanil combined with ropivacaine in epidural labor analgesia through prospective clinical trials, so…
- Trial name
- NCT05901441
- Testing
- Hydromorphone, Sufentanil, Ropivacaine
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Maternal and Child Health Hospital of Hubei Province
Preterm Birth, Pain, Procedural
Maternal Speech Decreases Pain Scores and Increases Oxytocin Levels in Preterm Infants During Painful Procedures
Preterm infants undergo early separation from parents and are exposed to frequent painful clinical procedures, with resultant short- and long-term effects on their neurodevelopment.
- Trial name
- NCT04762004
- Testing
- Maternal speech, Maternal singing, Standard care
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University of Geneva, Switzerland
Labor Pain, Epidural Analgesia
Different Spinal Needles Sizes and Dural Puncture Epidural For Labor Analgesia
The rationale behind the dural puncture epidural (DPE) technique lies in the fact that a dural perforation with a spinal needle purportedly creates a conduit for accelerated translocation of local anesthetics from the epidural to…
- Trial name
- NCT03389945
- Testing
- 25G Dural Puncture Epidural Block, 27G Dural Puncture Epidural Block
- Where
- 2 sites in Chile
- Volunteers
- 140 people
- Sponsor
- University of Chile
Labor Pain and to Reduce Pain, Birth Beliefs
THE EFFECT OF LISTENING TO SURAH ABESE (VERSES 19-20) DURING CHILDBIRTH ON VAGINAL BIRTH SELF-EFFICACY, BIRTH BELIEFS, AND PAIN PERCEPTION
We are planning this study to determine the effect of listening to verses 19-20 of Surah Abasa during labor on vaginal birth self-efficacy, birth beliefs, and pain perception.
- Conditions
- Labor Pain and to Reduce Pain, Birth Beliefs, Childbirth Self Efficacy
- Trial name
- NCT07865637
- Testing
- LISTENING TO VERSES 19-20 OF SURAH ABESE
- Volunteers
- 110 people
- Sponsor
- Ondokuz Mayıs University
Labor Pain and to Reduce Pain
Does the Volume of Medication Affect the Success of Labor Epidural Analgesia
The purpose of this study is to evaluate whether changing the volume and concentration of a medication affects the quality of pain relief and the side effects associated with labor epidural analgesia.
- Trial name
- EpiVol (NCT07684365)
- Testing
- administration of bupivacaine 7.5 mg and fentanyl 24 mcg every 40 minutes
- Volunteers
- 70 people
- Sponsor
- Beth Israel Deaconess Medical Center
Obstetric Pain
The Effect of the Transversus Abdominis Plane Block to Postoperative Analgesia for Cesarean Section
The transversus abdominis plane block (TAP block) has effect to postoperative analgesia for cesarean section with spinal anesthesia but it was limited for cesarean section with general anesthesia.
- Trial name
- TAP (NCT03634111)
- Testing
- TAP block, Morphine, Ropivacaine
- Where
- Vietnam
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gia Dinh People Hospital
Labor Pain
Intravenous Terbutaline to Facilitate Labor Epidural Catheter Placement
Labor pain is a major factor in making the placement of an epidural catheter difficult. The epidural, once in place and dosed, eventually decreases the parturient's pain.
- Trial name
- NCT01651962
- Testing
- Terbutaline, Fentanyl, 0.9% NaCl
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Kai Schoenhage
Newborn Morbidity, Pain
Epidemiology of Painful Procedures in Neonates
Sick or premature neonates are exposed to frequent painful and stressful procedures during their stay in neonatal intensive care units.
- Conditions
- Newborn Morbidity, Pain, Procedures, Intratracheal Intubation
- Trial name
- EPIPPAIN (NCT01346813)
- Where
- 21 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Hôpital Armand Trousseau