Clinical trials: Obstetrical Complications, active
Analgesia Obstetrical, Analgesia
Intrathecal Versus Epidural Morphine for Post-Cesarean Analgesia
Cesarean section is one of the most commonly performed surgical procedures worldwide, making effective management of acute postoperative pain a key issue in obstetric anesthesiology.
- Conditions
- Analgesia Obstetrical, Analgesia, Post Operative Pain, Patient Satisfaction
- Trial name
- NCT07386353
- Testing
- Intrathecal Morphine, Epidural Morphine
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospital Central do Funchal
Abnormal Uterine Bleeding, Unspecified, Benign Gynecological Disease
The Learning Curve of a Gynecology and Obstetrics Resident Performing Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) Hysterectomy in a University Hospital
This prospective observational study aims to evaluate the learning curve of obstetrics and gynecology residents performing Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) hysterectomy in a university hospital…
- Conditions
- Abnormal Uterine Bleeding, Unspecified, Benign Gynecological Disease, Adenomyosis of Uterus, Uterine Leiomyomas
- Trial name
- LC of V-NOTES (NCT07465822)
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people
- Sponsor
- Cukurova University
Labor Dystocia, Labor Complication
The Norwegian World Health Organisation Labour Care Guide Trial (NORWEL)
Appropriate and timely care during birth is critical to the survival and health of women and their babies. In 2020, the World Health Organization (WHO) presented the Labour Care Guide (LCG) as the new recommended tool for…
- Conditions
- Labor Dystocia, Labor Complication, Labor Onset and Length Abnormalities, Labor (Obstetrics)--Complications
- Trial name
- NORWEL (NCT05791630)
- Testing
- the labour care guide (LCG)
- Where
- 10 sites in Norway
- Volunteers
- 23,650 people, healthy volunteers welcome
- Sponsor
- Ostfold Hospital Trust
Postpartum Care, Maternal Health Care
Effect of a Respectful Maternity Care-Based Action Plan in Postpartum Care on Maternal and Neonatal Outcomes
This study will examine whether a Respectful Maternity Care-based action plan can improve the quality of postpartum care and maternal and newborn outcomes.
- Conditions
- Postpartum Care, Maternal Health Care, Newborn Health, Postpartum Depression (PPD)
- Trial name
- NCT07280000
- Testing
- Respectful Maternity Care Training and Action Plan
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- ilayda sel
Analgesia, Post Operative Pain
The Analgesic Efficacy of Vitamin B Complex in Critically Ill Obstetrics After Caesarean Section
We aim to investigate the value of vitamin B (B1, B6, B9, B12) on post-cesarean section analgesia in addition to the standard opioid-sparing multimodal regimen to achieve more robust analgesia with minimal side effects.
- Conditions
- Analgesia, Post Operative Pain, Cesarean Section
- Trial name
- NCT06446830
- Testing
- multimodal analgesia and vitamin B, standard multimodal analgesia
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Pregnancy Complications, Maternal Care Patterns
Melanated Group Midwifery Care (MGMC)
This study is being conducted to determine if a multi-level intervention for delivering maternity care can improve patient trust and engagement among Black birthing people.
- Conditions
- Pregnancy Complications, Maternal Care Patterns, Patient Engagement
- Trial name
- MGMC (NCT05365815)
- Testing
- Melanated Group Midwifery Care
- Where
- United States
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Female Genital Fistula, Incontinence
Adverse Outcomes Following Female Genital Fistula Repair
Following genital fistula repair, fistula repair breakdown and recurrence, persistent and incidence incontinence are major adverse outcomes, limiting women's health and wellbeing.
- Trial name
- Mulisa (NCT05437939)
- Where
- Uganda
- Volunteers
- 802 people
- Sponsor
- University of California, San Francisco
Postoperative Pain, Cesarean Delivery
Comparison of Intrathecal Bupivacaine With and Without Morphine for Post-operative Analgesia in Parturients Undergoing Elective Cesarean Section: A Randomized Controlled Trial
The goal of this clinical trial is to compare intrathecal bupivacaine with or without morphine for postoperative analgesia in patients undergoing elective cesarean section.
- Conditions
- Postoperative Pain, Cesarean Delivery, Analgesia, Obstetrical
- Trial name
- NCT07094802
- Testing
- Intrathecal morphine with bupivacaine, Hyperbaric Bupivicaine
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Bacterial Vaginosis
A Prospective, Randomized Controlled Study of the Probiotics as Adjuvant Treatment for Bacterial Vaginosis
The investigators are trying to determine if oral Probiotics(Umeta-mimi,30 days) with Metronidazole vaginal suppositories (7 days) is better than using Metronidazole vaginal suppositories(7 days) only in preventing the recurrence…
- Trial name
- NCT04771728
- Testing
- Metronidazole vaginal suppositories, Metronidazole vaginal suppositories and Probiotics(Umeta-mimi)
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Peking University Shenzhen Hospital
Sexual and Gender Minorities, Pregnancy Complications
Physical and Mental Health Among Sexual and Gender Minorities During Pregnancy, Birth and Postpartum
Mental illness increases the risk of adverse birth outcomes (e.g. preterm birth), obstetric complications (e.g. emergency caesarean, birth injuries), and birth trauma.
- Conditions
- Sexual and Gender Minorities, Pregnancy Complications, Obstetric Complication, Psychological Trauma
- Trial name
- NCT05354284
- Testing
- online questionnaire
- Where
- Sweden
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Pain Management, C Section
Pain After Scheduled Cesarean Delivery: Spinal Morphine With or Without Levobupivacaine Wound Infiltration
The goal of this observational study is to learn whether injecting a numbing medicine (levobupivacaine, a local anesthetic) into the surgical wound at the end of a cesarean delivery improves pain control in women who also receive…
- Conditions
- Pain Management, C Section, Obstetric Pain, Levobupivacaine
- Trial name
- LEVO-CS (NCT07859956)
- Testing
- Levobupivacaine, Intrathecal Morphine
- Where
- Colombia
- Volunteers
- 336 people
- Sponsor
- Fundación Santa Fe de Bogota
Gestational Trophoblastic Neoplasia
Toripalimab Plus Actinomycin-D As Fist-Line Treatment for GTN with FIGO Score 7
The goal of this clinical trial is to evaluate the efficacy and safety of toripalimab plus actinomycin-D as fist-line treatment in patients with gestational trophoblastic neoplasia with FIGO score 7.
- Trial name
- TA7 (NCT06020755)
- Testing
- Toripalimab, Actinomycin-D
- Where
- China
- Volunteers
- 17 people
- Sponsor
- Peking Union Medical College Hospital
Prenatal Anxiety, Prenatal Depression
Effectiveness of an Online Biopsychosocial Intervention to Improve Well-being and Mental Health During Pregnancy
This study aims to develop and implement a preventive intervention through a mobile application to help pregnant women feel better emotionally and cope with the changes of pregnancy in a more positive way.
- Conditions
- Prenatal Anxiety, Prenatal Depression, Wellbeing, Obstetrical Complications
- Trial name
- BienGestar (NCT06871397)
- Testing
- Biopsychosocial Cognitive Behavioral Intervention
- Where
- Spain
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Analgesia, Obstetrical, Post-Dural Puncture Headache
Intrathecal Catheter Placement Versus Resiting Epidural Catheter After Dural Puncture in Obstetric Patients
Epidural anesthesia represents the most popular method for pain relief during labour. Unintentional dural puncture (UDP) occurs in 0.4-1.5% of labour epidural analgesia, representing therefore the most common complication.
- Trial name
- ItaREVI (NCT05977361)
- Testing
- Resiting Epidural Catheter, Intrathecal Catheter Placement
- Volunteers
- 181 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Critical Illness, Difficult; Intubation, Postpartum, During Puerperium
Ultrasound Airway Assessment of Critically Ill Preeclamptic; Comparison Between Two Technique
Unexpected difficult airway exposes the patient to serious morbidity and even mortality. The changes in pregnancy and preeclampsia increase the risk of difficult intubation.
- Conditions
- Critical Illness, Difficult; Intubation, Postpartum, During Puerperium, Pre-Eclampsia
- Trial name
- NCT06651879
- Testing
- techniques of ultrasound examination of the airway
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Gestational Diabetes Mellitus (GDM)
Implementation and Evaluation of Bump2Baby and Me+ Programme for Gestational Diabetes Mellitus in Routine Maternity Care Setting.
Gestational diabetes mellitus (GDM) affects approximately 1 in 7 pregnancies globally and is associated with significant short and long-term health consequences for both mothers and infants.
- Trial name
- B2B&ME+ (NCT07189221)
- Testing
- Life Style Intervention
- Volunteers
- 3,600 people
- Sponsor
- University College Dublin
Labor and Childbirth, Labor (Obstetrics)--Complications
Development of a Multidimensional Predictive Model of Dystocic Labor. Association of Physical Condition and Psychosocial Factors With the Birth Process and Breastfeeding Success.
The goal of this observational study is to learn how a pregnant woman's physical fitness and emotional well-being can help predict the type of birth she will have (such as a natural vaginal birth versus a cesarean section or a…
- Conditions
- Labor and Childbirth, Labor (Obstetrics)--Complications, Hand Strength, Physical Conditioning, Human
- Trial name
- MPM-PD (NCT07635771)
- Where
- Spain
- Volunteers
- 420 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Hypertension in Pregnancy, Obstetrical Complications
Gestational Hypertension and Preeclampsia Blood Pressure (BP) Treatment Goals Less Than 140/90 vs. Less Than 160/110 mmHg: The GOALPOST Trial
This is a phase-III multi-center open-label randomized clinical trial of 4,120 individuals between 23 weeks, 0 days and 35 weeks, 6 days gestation with gestational hypertension or preeclampsia without severe features randomized…
- Trial name
- GOALPOST (NCT07746271)
- Testing
- Anti-hypertensive medication titrated to a BP goal of <140/90 mmHg, Usual Care: Anti-hypertensive medication for BP ≥160/110 mmHg titrated to a goal of < 160/110 mmHg
- Where
- 14 sites in United States
- Volunteers
- 4,120 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
Pregnancy Complications, SLE
Pregnancies Before the Diagnosis of Systemic Lupus Erythematosus
This is an observational, monocentric, retrospective cohort study. Its primary objective is to examine maternal and foetal outcomes in pregnancies that occurred before the diagnosis of systemic lupus erythematosus (SLE) in a…
- Trial name
- PREDILUP (NCT07148115)
- Testing
- Collect data on all pregnancies before and after diagnosis of SLE.
- Where
- 2 sites in Algeria
- Volunteers
- 50 people
- Sponsor
- University of Algiers
Neonatal Complication, Labor (Obstetrics)--Complications
Can the Use of a Next Generation Partograph Improve Neonatal Outcomes? (PICRINO)
The overall aim is to evaluate the impact of the use of two different guidelines for monitoring labor progress, the WHOs LCG versus standard care, on neonatal and maternal outcomes.
- Trial name
- NCT05560802
- Testing
- WHOs Labour care guide
- Where
- 24 sites in Sweden
- Volunteers
- 120,000 people
- Sponsor
- Linkoeping University