Clinical trials: Obstructed Defecation Syndrome
Obstructed Defecation Syndrome (ODS)
Effects of Botox in Obstructed Defecation Syndrome
The purpose of this study is to determine if Botulinum Toxin-A (Botox) injection will improve symptoms of constipation in obstructed defecation syndrome (ODS).
- Trial name
- NCT02160288
- Testing
- Botulinum Toxin-A, Normal Saline
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Massachusetts General Hospital
Constipation, Impaction, and Bowel Obstruction, TAMIS Mucosectomy
Outcome of TAMIS Mucosal Resection in Patients With ODS
Patients, aged 18 - 90 years, undergoing TAMIS mucosectomy at the Department of General Surgery at the Medical University of Vienna are enrolled into our study.
- Conditions
- Constipation, Impaction, and Bowel Obstruction, TAMIS Mucosectomy, Obstructed Defecation Syndrome
- Trial name
- NCT06522399
- Testing
- TAMIS mucosectomy
- Where
- Austria
- Volunteers
- 11 people
- Sponsor
- Medical University of Vienna
Rectal Prolapse, Rectocele
Long Term Results of STARR With Contour Transtar
Obstructed defecation syndrome (ODS) is a widespread and disabling syndrome. With this study the investigators want to evaluate the long term results of Stapled Transanal Rectal Resection (STARR) performed with Contour Transtar…
- Conditions
- Rectal Prolapse, Rectocele, Intussusception of Rectum
- Trial name
- LTSTARR (NCT02971332)
- Testing
- Stapled Transanal Rectal Resection
- Volunteers
- 113 people
- Sponsor
- University of Roma La Sapienza
Obstructive Defecation Syndrome, Outlet Obstruction
Dynamic MRI Evaluation Post Operative Stapled Trans Anal Rectal Resection (STARR) Procedure
The purpose of this study is to assess the effects of the Stapled Trans Anal Rectal Resection (STARR) procedure for patients with obstructive defecation syndrome.
- Trial name
- NCT00655382
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Rectal Prolapse, Defecation Disorder
Rectal Prolapse With ODS. STARR vs LVR.
The objective of the study will be to evaluate the clinical and functional outcome of patients with obstructed defecation sndrome (ODS) associated to internal rectal prolapse, treated with transanal prolassectomy (STARR) surgery…
- Conditions
- Rectal Prolapse, Defecation Disorder, Rectocele; Female, Surgery
- Trial name
- NCT04892108
- Testing
- STARR (Stapled Trans Anal Rectal Resection), LVR (Laparoscopic Ventral Rectopexy)
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University Hospital of Ferrara
Perineal Descent, Obstructed Defecation Syndrome (ODS)
Clinical Evaluation of the Femiset Device for Perineal Descent in Women
The University of Antwerp developed a device (Femiset) to alleviate defecation difficulties in women suffering from Descending Perineum Syndrome (DPS).
- Trial name
- FEMISET (NCT07039188)
- Testing
- Use device in home environment
- Volunteers
- 20 people
- Sponsor
- University Hospital, Antwerp
Obstructed Defaecation Syndrome, Anterior Rectocele
Rectocele Repair with or Without Internal Sphincter Botulinum Toxin Injection: a Prospective Randomized Trial
This is a single-centre, prospective randomized controlled trial on female patients with anterior rectocele associated with obstructed defecation syndrome
- Trial name
- NCT06804993
- Testing
- Transvaginal repair & botulinum toxin type A injection, Transvaginal repair & distilled water injection
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Obstructed Defecation Syndrome (ODS)
Stapled TransAnal Rectal Resection (STARR): Clinical and Radiological Outcome
To evaluate the correlation between clinical and radiological outcome after Stapled TransAnal Rectal Resection (STARR)
- Trial name
- NCT00587080
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- University of Zurich
Constipation
International Multicenter Prospective Transtar Registry
Obstructed Defecation Syndrome (ODS) describes a condition which is characterized by chronic constipation. The symptoms of ODS include abdominal pain or cramping, irregular bowel frequency and the feeling of not having emptied…
- Trial name
- NCT00909116
- Testing
- Stapled Transanal Rectal Resection with Contour Transtar
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Ethicon Endo-Surgery (Europe) GmbH
Obstructive Defecation Syndrome, Chronic Constipation
Study of Stapled Transanal Rectal Resection (STARR) Surgery in Refractory Constipation Associated With Obstructive Defecation Syndrome (ODS)
The primary purpose of this study is to determine how effective and how durable STARR (stapled transanal rectal resection) surgery is in relieving symptoms of intractable constipation associated with obstructive defecation…
- Conditions
- Obstructive Defecation Syndrome, Chronic Constipation, Rectocele, Intussusception
- Trial name
- NCT00256984
- Testing
- Stapled Transanal Resection (STARR) with Transtar (PROXIMATE®) 33 mm Circular Stapler
- Where
- 7 sites in United States
- Volunteers
- 75 people
- Sponsor
- Ethicon Endo-Surgery
Surgery, Obstructive Defecation Syndrome
Mental Health Outcome After Surgery for Obstructed Defecation Syndrome (ODS)
Background: Obstructed Defecation Synsdrome (ODS) causes people to strain and sometimes need help to go to the toilet. They think about going to the toilet a lot, which makes their lives worse.
- Conditions
- Surgery, Obstructive Defecation Syndrome, Mental Health Issue, Depression/Anxiety
- Trial name
- MentODSSurg (NCT06502184)
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Evangelisches Klinikum Köln Weyertal gGmbH
Obstructive Defecation Syndrome, Chronic Constipation
Laparoscopic Ventral Mesh Rectopexy Combined With or Without Stapled Trans-anal Rectal Resection for Obstructed Defecation Syndrome
Obstructed defecation syndrome (ODS) is a common problem in women. Rectal prolapse and rectocoele are frequently identified in patients with ODS.
- Conditions
- Obstructive Defecation Syndrome, Chronic Constipation, Rectal Prolapse
- Trial name
- NCT03060330
- Testing
- Modified Laparoscopic Ventral Mesh Rectopexy, Modified Laparoscopic Ventral Mesh Rectopexy Combined with Stapled Trans-anal Rectal Resection
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Renmin Hospital of Wuhan University
Obstructed Defaecation Syndrome
Biofeedback Therapy Versus Botox Injection in Treatment of Dyssynergic Defecation.
assessment the Improvement symptoms of obstructed defecation after biofeedback training versus botulinum toxin injection
- Trial name
- NCT06724250
- Testing
- Biofeedback therapy, Botulinum Toxin A (Botox )
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Mansoura University
Obstructed Defaecation Syndrome
Obstructed Defaecation: Proctography Versus Ultrasound in Symptomatic Patients
Obstructed defaecation syndrome is a common problem in which patients experience difficulty to evacuate stools and feel that the bowel is incompletely empty, which causes the need to put fingers in to the rectum or vaginal to…
- Trial name
- OPUS (NCT02239302)
- Where
- United Kingdom
- Volunteers
- 131 people
- Sponsor
- Croydon University Hospital
Obstructed Defecation Syndrome, Rectocele
Stapled TransAnal Rectal Resection (STARR) With Contour® TranstarTM
The stapled transanal rectal resection (STARR procedure) is an effective treatment for obstructed defecation syndrome (ODS) caused by intussusception and rectocele.
- Conditions
- Obstructed Defecation Syndrome, Rectocele, Intussusception, SNS
- Trial name
- STARR (NCT00673400)
- Testing
- Stapled transanal rectum resection
- Where
- Switzerland
- Volunteers
- 52 people
- Sponsor
- Cantonal Hospital of St. Gallen
MRI Defecography, ODS
Role of MRI Defecography in Diagnosis of Obstructed Defecation Syndrome
The aim of the study was to assess the advantages of dynamic magnetic resonance imaging defecography to elucidate the underlying anatomic and pathophysiologic background in obstructed defecation patients to guide physicians in…
- Trial name
- NCT03841006
- Testing
- MRI
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alshimaa Abdalkreem
Sensation of Inadequate Defecation, Rectal Prolapse
Surgical Treatment of Obstructed Defecation Syndrome
Obstructed Defecation is a profoundly disabling condition. Many different surgical procedures has been introduced to treat patients affected by this disease. The most used are STARR and ventral rectopexy.
- Conditions
- Sensation of Inadequate Defecation, Rectal Prolapse, Rectocele
- Trial name
- PRO-REST (NCT01899209)
- Testing
- STARR, Laparoscopic Ventral Rectopexy
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna