Clinical trials: Obstructive Apnea
Bruxism, Temporomandibular Joint Disorders
Aspects Associated With Obstructive Sleep Apnea, Bruxism and Orofacial Pain
This study evaluated the influence of the sleep bruxism (SB), awake bruxism (AB) and obstructive sleep apnea syndrome (OSAS) on the signs and symptoms of temporomandibular disorders (TMD).
- Conditions
- Bruxism, Temporomandibular Joint Disorders, Obstructive Sleep Apnea Syndrome
- Trial name
- NCT03766464
- Testing
- Evaluation of TMD and pain sensitivity, Evaluation of SB, Evaluation of AB
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Obstructive Sleep Apnea (OSA)
Evaluating the Efficacy of PAP Therapy for Treating OSA in the Home Environment
This study will take between 4-6 months (with first patient first visit to last patient last visit expected to span 3-4 months across all study sites).
- Trial name
- NCT04744038
- Testing
- Positive Airway Pressure (PAP) Therapy
- Where
- 2 sites in United States, Australia
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- ResMed
Obstructive Sleep Apnea
Memory Consolidation in Obstructive Sleep Apnea
The overarching goal of the research proposed here is to test the hypothesis (i) that the pathophysiological mechanisms of OSA lead to deterioration in sleep-dependent memory consolidation across memory systems, with the genetic…
- Trial name
- NCT01800786
- Testing
- CPAP
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Obstructive Sleep Apnea
Cardiopulmonary Exercise Test in Patient With Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) can be described as a condition characterized by repetitive obstruction of the upper airway resulting in oxygen desaturation and awakening from sleep, loud snoring, and increased daytime sleepiness .
- Trial name
- NCT03300700
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Obstructive Sleep Apnea (SAOS), Aging
Evaluation of the Impact of Sleep Apnea on Cerebral Volumetry According to Age
Sleep apnea is a common disease in the general population and more particularly in elderly subjects in whom prevalence can reach 30 % after 70 years old.
- Trial name
- VOILAGE (NCT02358811)
- Testing
- Magnetic resonance imaging (MRI), Cognitive assessment
- Where
- France
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Pregnant Women
Fetal Outcome of Sleep Disordered Breathing During Pregnancy
Sleep disordered breathing (SDB) is a frequent disorder characterized by some combination of repeated events of partial or complete upper airway obstruction during sleep, disruption of normal ventilation, hypoxemia, and sleep…
- Trial name
- NCT00931099
- Where
- Israel
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Obstructive Sleep Apnea, Pregnancy Related
Obstructive Sleep Apnea Treatment and Insulin Sensitivity in Pregnancy
This study will evaluate the effect of treatment of obstructive sleep apnea on insulin sensitivity in pregnant women. Women in their third trimester of pregnancy will be randomized to receive treatment or no treatment for one…
- Conditions
- Obstructive Sleep Apnea, Pregnancy Related, Insulin Sensitivity
- Trial name
- NCT04013399
- Testing
- Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Barnes-Jewish Hospital
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Sleep Apnea Syndromes
The Number and Function of Regular T Cell in Patients With Obstructive Sleep Apnea
To compare the number and function of regular T cell of patients with obstructive sleep apnea (OSA) versus that of age-, gender- and BMI (body mass index)-matched controls
- Trial name
- NCT02342028
- Testing
- OSA
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Obstructive Sleep Apnea, Pulmonary Hypertension
Role of Heme-oxygenase (HO) and Nitric Oxide (NO) Pathway in Patients With Obstructive Sleep Apnea (OSA) and Pulmonary Hypertension (PH)
Research design: This is a controled prospective study. Methodology: Patients with newly diagnosed and untreated OSA with total apnea-hypopnea index (AHI) >5/h, and control (AHI<5/h) will be recruited from the Long Beach VA sleep…
- Trial name
- NCT02368171
- Testing
- measure exhaled carbon monoxide and nitric oxide
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Southern California Institute for Research and Education
Asthma, Atrial Fibrillation
Improving Quality by Maintaining Accurate Problems in the EHR
The overall goal of the IQ-MAPLE project is to improve the quality of care provided to patients with several heart, lung and blood conditions by facilitating more accurate and complete problem list documentation.
- Conditions
- Asthma, Atrial Fibrillation, Chronic Obstructive Pulmonary Disease, Coronary Artery Disease
- Trial name
- IQ-MAPLE (NCT02596087)
- Testing
- Problem List Suggestion
- Where
- 4 sites in United States
- Volunteers
- 2,386 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Obstructive Sleep Apnea, Insomnia
Comorbid Insomnia and Sleep Apnea
Insomnia and OSA coexist in clinical populations, but the prevalence of comorbid insomnia among OSA patients in the community and risk factors remain poorly known.
- Trial name
- NCT04274400
- Where
- Brazil
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Obstructive Sleep Apnea, HIV/AIDS
The Pathogenesis of OSA in People Living With HIV
The purpose of this study is to help us understand how HIV and/or Anti-Retroviral Therapy (ART) may predispose individuals to Obstructive Sleep Apnea (OSA). The traditional risk factors for OSA are weight and age.
- Trial name
- NCT03064204
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Obesity, Pulmonary Atelectasis
Effects of PEEP on Heart and Lungs in Obese Subjects
Aim of this study is to better understand pathophysiology of the alteration of respiratory mechanics and cardiovascular function in obese volunteer subjects.
- Conditions
- Obesity, Pulmonary Atelectasis, Obesity Hypoventilation Syndrome, Magnetic Resonance Imaging
- Trial name
- NCT02523352
- Testing
- Non-Invasive Ventilation, Esophageal catheter positioning
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Obstructive Sleep Apnea of Adult
An Extension Study to Assess the Long-term Safety of the Genio® System
The objective of this study is to assess the long-term safety of the Genio® system in adult OSA patients with and without complete concentric collapse of the soft palate who have successfully been implanted with the Genio IS in a…
- Trial name
- OLE (NCT05939141)
- Testing
- Genio System
- Where
- 7 sites in Australia
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Nyxoah S.A.
Obstructive Sleep Apnea
A Research Study for Children About Heart Changes and Obstructive Sleep Apnea (OSA)
In this research study the investigators want to learn more about the risk of developing blood vessel and heart disease from night-time sleep apnea.
- Trial name
- NCT01837459
- Where
- United States
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Obstructive Sleep Apnea Syndrome, Obesity
Influence of nCPAP on Metabolic Consequences Associated With OSAS
Context: Obstructive sleep apnea syndrome (OSAS) is associated with cardiovascular morbidity. Recurrent episodes of occlusion of upper airways during sleep result in hormonal changes that may predispose to high cardiovascular…
- Trial name
- NCT00435643
- Testing
- nasal continuous positive airway pressure
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Sleep Apnea, Obstructive
Validation of a Novel Device for Screening Patients With Symptoms of Obstructive Sleep Apnea
The purpose of this study is to evaluate the sensitivity and specificity of the Belun Ring Pulse Oximetry system for screening of obstructive sleep apnea (OSA) in adults during standard polysomnography sleep study conditions.
- Trial name
- NCT04121923
- Testing
- Belun Ring Pulse Oximeter
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Belun Technology Company Limited
Obstructive Sleep Apnea Syndrome
Ketamine Infusion for Pediatric Patients With Obstructive Sleep Apnea Syndrome (OSAS) After Tonsillectomy
The study will evaluate the post-operative morphine-sparing effect, pain reduction, and side effects of a continuous ketamine infusion after tonsillectomy in pediatric patients.
- Trial name
- KOSATA (NCT02425202)
- Testing
- Ketamine, Saline infusion
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Obstructive Sleep Apnea, Sleep Apnea
Validity and Reliability of the 6-Minute Pegboard and Ring Test (6PBRT) in Adults With Obstructive Sleep Apnea Syndrome
Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder characterized by recurrent upper airway obstruction during sleep, leading to intermittent hypoxia and sleep fragmentation.
- Trial name
- NCT07465874
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mardin Artuklu University