Clinical trials: Obstructive Apnea
Sleep Apnea, Obstructive, Sleep Apnea, Central
Sparkle Respiratory Effort Validation
This study has been developed in order to demonstrate the validity of the Sparkle respiratory effort signal.
- Trial name
- NCT04630639
- Testing
- Sparkle
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Obstructive Sleep Apnea, Diabetes Mellitus
Assessing the Risk of Developing Type II Diabetes Using Serum Biomarkers in Patients Diagnosed With Obstructive Sleep Apnea
The investigators plan to recruit 140 patients (35 subjects in each group) over a period of 18 months in a prospective study of matched/paired case-control subjects across the four groups to measure the 5-year risk of developing…
- Trial name
- OSA & DM (NCT01447251)
- Testing
- PreDx Diabetes Risk Score
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mike O'Callaghan Military Hospital
Obstructive Sleep Apnea of Adult, Mild Cognitive Impairment
The Relationship Between Obstructive Sleep Apnea and Alzheimer's Disease: Evidence and Effectiveness
The research plan to enroll 15 simple snoring patients (apnea/hypopnea <5, control group), 30 severe OSA patients (apnea/hypopnea >30, treatment group), and 15 mild cognitive impairment patients (comparative group).
- Trial name
- OSA (NCT05433883)
- Testing
- sleep surgery
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Obstructive Sleep Apnea
Quantitative Genioglossal Muscle Strength in Obstructive Sleep Apnea (OSAS)
Quantitative Genioglossal muscle strength in Obstructive Sleep Apnea (OSAS) defined in the clinical spectrum of subjects with Snoring Disturbance, Oral Appliance Therapy Responsive, and CPAP Responsive
- Trial name
- EatonOSAS (NCT02695667)
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Sleep Apnea
New Approach in the Study of the Autonomic Nervous System Through Cardiac Variability in Sleep Apnea Syndrome.
The main objective of this study is to compare the different variations of the cardiac variability index measured thanks to the technique developed by the CIC-IT between subjects with severe SAS and healthy subjects with sleep…
- Trial name
- HRVSAS (NCT06808464)
- Where
- France
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Obstructive Sleep Apnea
Obstructive Sleep Apnea and Genes Expression
Obstructive sleep apnea is a multi-component disease. This study will test the hypotheses that hypoxia per se modulates gene expression in animal model of sleep apnea and these results may be translated with alterations that…
- Trial name
- HIP (NCT01392339)
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- Brazil
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Associacao Fundo de Incentivo a Psicofarmcologia
Obstructive Sleep Apnea (OSA)
Biomarkers for Obstructive Sleep Apnea
The purpose of the study is to: recruit subjects with untreated sleep apnea; assess overnight changes in their blood and urine chemicals review the overnight changes in blood and urine chemicals after they have been treated for…
- Trial name
- BOSA (NCT00834509)
- Testing
- CPAP
- Where
- United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Obstructive Sleep Apnea
Comprehensive Analysis of Respiratory Events Using Smartphone Systems
Earlier studies suggest that acoustical analysis of snoring sounds can identify obstructive sleep apnea (OSA). The goal of the current study is to refine and validate algorithms for OSA diagnosis.
- Trial name
- CARESS (NCT03457428)
- Where
- 4 sites in United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Resonea, Inc
Metabolic Syndrome, Obesity Hypoventilation Syndrome
Obesity-hypoventilation in Metabolic Syndrom Patients
The purpose of the study is to determined the prevalence of obesity-hypoventilation syndrome in patients with metabolic syndrom.
- Conditions
- Metabolic Syndrome, Obesity Hypoventilation Syndrome, Capnography
- Trial name
- NCT04839419
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- SOS Oxygene Mediterranee
Obstructive Sleep Apnea, Pulmonary Hypertension
Role of Heme-oxygenase (HO) and Nitric Oxide (NO) Pathway in Patients With Obstructive Sleep Apnea (OSA) and Pulmonary Hypertension (PH)
Research design: This is a controled prospective study. Methodology: Patients with newly diagnosed and untreated OSA with total apnea-hypopnea index (AHI) >5/h, and control (AHI<5/h) will be recruited from the Long Beach VA sleep…
- Trial name
- NCT02368171
- Testing
- measure exhaled carbon monoxide and nitric oxide
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Southern California Institute for Research and Education
Sleep, Obstructive Sleep Apnea
Study Watch Sleep Metric Performance Characterization Study
This is a multi-center, single-arm, prospective performance evaluation study designed to assess performance of sleep metrics calculated from sensor data that is collected from two versions of the Verily Study Watch as compared to…
- Conditions
- Sleep, Obstructive Sleep Apnea, Insomnia
- Trial name
- NCT05276362
- Testing
- Study Watch, Actiwatch
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Verily Life Sciences LLC
Obstructive Sleep Apnea
Whitsundays (Nasal) Singapore External Clinical Study 1 Protocol
Each Whitsunday mask or AirFit N30i Quiet mask is worn for 7 nights. The overall purpose of this study is to evaluate the performance of the Whitsundays nasal mask system (a prototype mask) compared to the ResMed AirFit N30i…
- Trial name
- NCT05255744
- Testing
- Positive Airway Pressure (PAP) Therapy
- Where
- Singapore
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ResMed
Obstructive Sleep Apnea, Vascular Diseases
Sleep Apnea, Cardiovascular and Exercise Study
Obstructive sleep apnea (OSA) results in vascular dysfunction, which increases the risk of cardiovascular disease. In contrast, exercise confers cardioprotection through improvements in vascular health.
- Conditions
- Obstructive Sleep Apnea, Vascular Diseases, Obesity
- Trial name
- NCT03219749
- Testing
- exercise training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Towson University
Obstructive Sleep Apnoea
Dynamic Alterations of Tongue in Sleep Apnoea Hypopnea Syndrome During Sleep
The aim of this study was to evaluate the dynamic changes of the tongue in patients with obstructive sleep apnoea hypopnea syndrome (OSAHS) during sleep and while awake by using Ultrafast Magnetic Resonance Imaging (UMRI)
- Trial name
- NCT01687855
- Testing
- Ultrafast Magnetic Resonance Imaging
- Where
- China
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Obstructive Sleep Apnea
Pathophysiology of the Upper Airway in Patients With COPD and Concomitant OSA
The purpose of study is to evaluate the physiologic effects of pulmonary tissue/structural changes associated with COPD and upper airway inflammation on upper airway collapsibility.
- Trial name
- NCT02567448
- Testing
- Sleep and pulmonary physiologic measurements
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Cardiopulmonary Failure, Myocardial Infarction (MI)
COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG Wearable
The COR-INSIGHT trial aims to evaluate the effectiveness of Peerbridge COR advanced ambulatory ECG wearables (COR 1.0 and COR 2.0) in accurately and non-invasively detecting cardiovascular and cardiopulmonary conditions using…
- Conditions
- Cardiopulmonary Failure, Myocardial Infarction (MI), Heart Decompensation, Heart Failure
- Trial name
- COR-INSIGHT (NCT06763549)
- Testing
- SUBPROTOCOL A, SUBPROTOCOL B, SUBPROTOCOL C
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Peerbridge Health, Inc
Obstructive Sleep Apnea
Evaluation of Potential Biomarkers for Obstructive Sleep Apnea and the Effect of Positive Pressure Treatment
Potential biomarkers for obstructive sleep apnea (OSA), and full genomic screening will be evaluated and correlated to the degree of OSA and to effect of CPAP-treatment measured by polygraphy.
- Trial name
- NCT01976052
- Where
- Sweden
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Sleep Apnea, Obstructive
The Changes of Patterns of Microarray in Patients With Obstructive Sleep Apnea
The aim of this study are (1) To genome-wide profile the gene expression patterns of peripheral blood mononuclear cell (PBMC) in patients with obstructive sleep apnea (OSA) (2) To profile the gene expression patterns change…
- Trial name
- NCT00498849
- Testing
- CPAP
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Sleep Apnea Syndromes
The Number and Function of Regular T Cell in Patients With Obstructive Sleep Apnea
To compare the number and function of regular T cell of patients with obstructive sleep apnea (OSA) versus that of age-, gender- and BMI (body mass index)-matched controls
- Trial name
- NCT02342028
- Testing
- OSA
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Obstructive Sleep Apnea, Inflammation
A Community Study of the Risk for Obstructive Sleep Apnea and Respiratory Inflammation in an Adult Chinese Population
We aimed to investigate the relationship between obstructive sleep apnea (OSA) risk and respiratory inflammation evaluated by the exhaled breath condensate （EBC）interleukin-6 IL-6 and plasma SP-D, based on the Berlin…
- Conditions
- Obstructive Sleep Apnea, Inflammation, Exhaled Breath Condensate, Surveys and Questionnaires
- Trial name
- NCT04832711
- Where
- China
- Volunteers
- 1,270 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital