Clinical trials: Obstructive Apnea
Chronic Obstructive Pulmonary Disease, Sleep Related Hypoventilation
Health Outcomes With CPAP or NIV in Patients With COPD and a Sleep Related Breathing Disorder
Chronic obstructive pulmonary disease (COPD) is a chronic lung disease affecting an estimated 1 in 10 Canadians. Symptoms include persistent shortness of breath, cough and sputum production.
- Conditions
- Chronic Obstructive Pulmonary Disease, Sleep Related Hypoventilation, Obstructive Sleep Apnea, Hypoventilation
- Trial name
- NCT05623709
- Testing
- Positive airway pressure with continuous positive airway pressure or noninvasive ventilation
- Where
- Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Obstructive Sleep Apnea, Insulin Resistance
Exploring the Role of Adipocyte Fatty Acid Binding Protein in the Association of Obstructive Sleep Apnea and Metabolic Dysfunction
Adipocyte fatty acid binding protein (A-FABP) is a member of the FABP super family, is abundant in adipocytes and macrophages. Regulatory functions of A-FABP in lipid and glucose metabolism have been described, and it is…
- Conditions
- Obstructive Sleep Apnea, Insulin Resistance, Metabolic Syndrome, Inflammation
- Trial name
- NCT01173432
- Testing
- continuous positive airway pressure
- Where
- Hong Kong
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Obstructive Sleep Apnoea
Dynamic Alterations of Tongue in Sleep Apnoea Hypopnea Syndrome During Sleep
The aim of this study was to evaluate the dynamic changes of the tongue in patients with obstructive sleep apnoea hypopnea syndrome (OSAHS) during sleep and while awake by using Ultrafast Magnetic Resonance Imaging (UMRI)
- Trial name
- NCT01687855
- Testing
- Ultrafast Magnetic Resonance Imaging
- Where
- China
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Obstructive Sleep Apnea, Obstructive Sleep Apnea (OSA)
Identification of Biomarkers of Obstructive Sleep Apnea.
Obstructive sleep apnea (OSA) is a common sleep disorder associated with intermittent hypoxia, systemic inflammation, oxidative stress, and an increased risk of cardiovascular and metabolic diseases.
- Conditions
- Obstructive Sleep Apnea, Obstructive Sleep Apnea (OSA), Obstructive Sleep Apnea (OSAS), Obstructive Sleep Apnea (SAOS)
- Trial name
- NCT07723144
- Testing
- Positive Airway Pressure (PAP) Therapy
- Where
- Poland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Obstructive Sleep Apnea, Fat Disorder
Metabolism and Sleep Apnea Treatment
The purpose of this research study is to see if obstructive sleep apnea (OSA) is associated with abnormalities in fat metabolism.
- Trial name
- MaST (NCT05539716)
- Testing
- PAP Therapy, Lifestyle Counseling Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Miami
Obstructive Sleep Apnea
Comprehensive Analysis of Respiratory Events Using Smartphone Systems
Earlier studies suggest that acoustical analysis of snoring sounds can identify obstructive sleep apnea (OSA). The goal of the current study is to refine and validate algorithms for OSA diagnosis.
- Trial name
- CARESS (NCT03457428)
- Where
- 4 sites in United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Resonea, Inc
Obstructive Sleep Apnea
Obstructive Sleep Apnea and Genes Expression
Obstructive sleep apnea is a multi-component disease. This study will test the hypotheses that hypoxia per se modulates gene expression in animal model of sleep apnea and these results may be translated with alterations that…
- Trial name
- HIP (NCT01392339)
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- Brazil
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Associacao Fundo de Incentivo a Psicofarmcologia
Recurrent Tonsillitis, Peritonsillar Abscess
Auricular Acupuncture for The Treatment of Post-Tonsillectomy Pain
The goal of this study is to assess the role of battlefield acupuncture in the reduction of pain scores status post adult tonsillectomy.
- Conditions
- Recurrent Tonsillitis, Peritonsillar Abscess, Obstructive Sleep Apnea
- Trial name
- NCT01790477
- Testing
- Auricular Acupuncture
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Sleep Apnea, Obstructive, Larynx
Accuracy of the Sensory Test Using the Laryngopharyngeal Endoscopic Esthesiometer in Obstructive Sleep Apnea
This is a prospective double blinded randomized crossover controlled trial aiming at validating the measurement of laryngopharyngeal mechanosensitivity in patients with suspected OSA using a recently developed laryngopharyngeal…
- Conditions
- Sleep Apnea, Obstructive, Larynx, Sensory Disorder
- Trial name
- NCT03109171
- Testing
- Laryngopharyngeal sensory test
- Where
- 2 sites in Colombia
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Fundación Neumologica Colombiana
Sleep Apnea, Obstructive
Correlation Between Preeclampsia and Positive for Obstructive Sleep Apnea Screening Test: STOPBANG Questionnaire
The purpose of this study is to find the correlation between high risk OSA (obstructive sleep apnea) patient, based on Stop-bang screening tool and preeclampsia
- Trial name
- NCT02800798
- Testing
- Preeclampsia positive
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Ramathibodi Hospital
Obstructive Sleep Apnea
Lifestyle Interventions for Seniors With Apnea
The overall goal of this study is to determine the efficacy of a lifestyle intervention, consisting of a weight loss diet and exercise on sleep apnea in older adults.
- Trial name
- NCT01422863
- Testing
- Lifestyle Intervention
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Obstructive Sleep Apnea, Pregnancy Related
Obstructive Sleep Apnea Treatment and Insulin Sensitivity in Pregnancy
This study will evaluate the effect of treatment of obstructive sleep apnea on insulin sensitivity in pregnant women. Women in their third trimester of pregnancy will be randomized to receive treatment or no treatment for one…
- Conditions
- Obstructive Sleep Apnea, Pregnancy Related, Insulin Sensitivity
- Trial name
- NCT04013399
- Testing
- Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Barnes-Jewish Hospital
Sleep Apnea, Obstructive
Undetected Sleep Apnea in the Postanesthesia Acute Care Unit (PACU)
The primary aim is to determine whether patients with suspected OSAHS as predicted by the STOP-BANG questionnaire will have an increased length of stay (LOS) in the postanesthesia acute care unit (PACU) compared with those…
- Trial name
- NCT02166879
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Sleep Apnea Syndrome, Obstructive, Bruxism, Sleep-Related
Bruxism Induced by Obstructive Sleep Apnoea.
The relationship between obstructive sleep apnea (OSA), sleep bruxism, and temporomandibular disorders is becoming clearer, but data on how upper airway volume affects bruxism due to OSA is limited.
- Conditions
- Sleep Apnea Syndrome, Obstructive, Bruxism, Sleep-Related, Upper Respiratory Tract Illness
- Trial name
- OSA Bruxism (NCT07511946)
- Testing
- Upper airway volume assessment using Cone-Beam Computed Tomography (CBCT) and Polysomnography, Upper airway volume assessment using Cone-Beam Computed Tomography (CBCT)
- Where
- Poland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
OSA
Impact of Intermittent Hypoxia on Neutrophil Extracellular Traps
This prospective observational study will enroll 60 moderate-to-severe OSA patients (AHI≧15/hour, 30 obese [BMI>=27] \& 30 non-obese [BMI<27]) and 40 age-, gender-, BMI-matched controls without OSA.
- Trial name
- NCT05485688
- Testing
- sleep apnea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Obstructive Sleep Apnea
Validation and Usability Study of the SleepView+ Home Sleep Testing System for the Evaluation of Moderate to Severe Obstructive Sleep Apnea.
The goal of this observational study is to characterize the performance of the SleepView+ home sleep test system for the evaluation of moderate to severe obstructuve sleep apnea (OSA) in adult and pediatric patients (ages 12 and…
- Trial name
- NCT07476313
- Testing
- SleepView+
- Where
- 4 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Beacon Biosignals
Obstructive Sleep Apnea
Skiin-PSG Sleep Apnea
The goal of this observational study is to develop new algorithms to detect apnea and/or hypopnea to provide additional insights to Skiin users and to their circle of care to validate and/or improve the current algorithms of the…
- Trial name
- NCT06247878
- Testing
- Skiin underwear chest band
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Myant Medical Corp.
Sleep Apnea Hypopnea Syndrome, COPD
Prevalence of Sleep Disordered Breathing in a Lung Cancer Screening Cohort
Prospective study of sleep disordered breathing in a lung cancer screening cohort.
- Conditions
- Sleep Apnea Hypopnea Syndrome, COPD, Emphysema, Lung Cancer
- Trial name
- SAILS (NCT02687997)
- Testing
- poligraphy
- Where
- Spain
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Hypertension Secondary
Characteristics of Obstructive Sleep Apnea Syndrome Related Hypertension and the Effect of Continuous Positive Airway Pressure Treatment on Blood Pressure
Obstructive sleep apnea syndrome (OSAS) causes nocturnal chronic intermittent hypoxia (CIH) that contributes to the development of hypertension.
- Trial name
- NCT03246022
- Testing
- continuous positive airway pressure
- Where
- China
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Huai'an No.1 People's Hospital
Obstructive Sleep Apnea
Developement of TipTraQ Home Sleep Test
The clinical study aims to develop and fine-tune the TipTraQ system, created by PranaQ, for home sleep apnea screening. The system comprises a wearable device and a cloud-based AI for estimating Total Sleep Time (TST) and…
- Trial name
- NCT06474351
- Where
- Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- PranaQ Pte. Ltd.