Clinical trials: Obstructive Apnea
Obstructive Sleep Apnea Syndrome
Inflammatory Markers in Infants With Obstructive Sleep Apnea
Obstructive sleep apnea syndrome (OSAS) is a common disorder in children (2-3%). OSAS in turn, is associated with significant behavioral, learning, and heart problems.
- Trial name
- NCT01058590
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Obstructive Sleep Apnea of Adult, Difficult or Failed Intubation
Changes in Difficult Airway Markers After Surgery for Obstructive Sleep Apnoea Syndrome
This study investigates the changes in difficult airway markers at 6 months post operatively in patients undergoing obstructive sleep apnoea surgery
- Trial name
- NCT06447818
- Testing
- Change in airway markers
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Kocaeli City Hospital
Obstructive Sleep Apnea
Auto Bilevel Adherence Following a Poor Initial Encounter With Continuous Positive Airway Pressure (CPAP)
The primary objective outcome is the proportion of participants compliant (at least four hours of use per night for all nights) in the Auto Bilevel group compared to the continuous positive airway pressure (CPAP) group after 90…
- Trial name
- BiPAPRescue (NCT02522442)
- Testing
- CPAP, Auto BiLevel
- Where
- 3 sites in United States
- Volunteers
- 51 people
- Sponsor
- Philips Respironics
Coronary Artery Disease, Obstructive Sleep Apnea
Continuous Positive Airway Pressure (CPAP) Treatment in Coronary Artery Disease and Sleep Apnea
Obstructive sleep apnea (OSA) worsens the prognosis in patients with coronary artery disease (CAD). Many of these subjects do not report daytime sleepiness, and therefore, are not considered for OSA treatment with continuous…
- Trial name
- RICCADSA (NCT00519597)
- Testing
- ResMed S8 (Auto-CPAP)
- Where
- Sweden
- Volunteers
- 511 people
- Sponsor
- Skaraborg Hospital
Sleep Apnea, Obstructive
Myofunctional Training for Obstructive Sleep Apnea Patients After Transoral Robotic Surgery
Background: Obstructive Sleep Apnea Syndrome (OSA) is a kind of sleep disorder. The symptoms are intermittent, partial or complete upper airway collapse, seriously impacting oxygen saturation and oxidative stress.
- Trial name
- NCT04876482
- Testing
- transoral robotic surgery, oral appliance, using continuous positive airway pressure
- Where
- Taiwan
- Volunteers
- 81 people
- Sponsor
- National Cheng-Kung University Hospital
Obstructive Sleep Apnea of Adult
Efficacy of Oropharyngeal Exercises for Patients With Obstructive Sleep Apnea Using Mandibular Advancement Device
Combined treatment with MAD and OE for adult patients with obstructive sleep apnea can significantly (i) improve muscle strength and endurance; (ii) reduce the severity of sleep apnea.
- Trial name
- NCT05717959
- Testing
- Oropharyngeal Exercises
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Cheng-Kung University Hospital
Obstructive Sleep Apnea
Comparing Fitbit® Quality of Measured Sleep to Sleep Measured by Polysomnography in the Sleep Lab
This study is to evaluate a commercial tool on the market (Fitbit®) that also quantifies sleep. No one has studied how pediatric patients perform with it and how accurate it is in measuring their quality of sleep.
- Trial name
- NCT03066479
- Testing
- Fitbit, OSA questionnaire, Polysomnography
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Vidya Raman
Sleep Apnea, Obstructive, Continuous Positive Airway Pressure
Evaluating Behavioral Treatments to Improve Adherence to Continuous Positive Airway Pressure (CPAP) Therapy in People With Obstructive Sleep Apnea (The BREATHE Study)
Obstructive sleep apnea (OSA) is a serious sleep disorder in which a person repeatedly stops breathing or experiences shallow breathing for short periods of time during sleep.
- Trial name
- BREATHE (NCT00623246)
- Testing
- MET, ED
- Where
- United States
- Volunteers
- 306 people
- Sponsor
- National Jewish Health
Obstructive Sleep Apnea, Heart Failure; With Decompensation
Sleep Disordered Breathing in Acute Congestive Heart Failure
The goal of this study is to determine if sleep disordered breathing results in a measurable degree of overnight myocardial stress/injury in patients with acutely decompensated congestive heart failure.
- Trial name
- NCT03804827
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- University of California, San Diego
Obesity Hypoventilation Syndrome, Obstructive Sleep Apnea
Medico-economics and QoL of Obese Patients Followed by Medical Analysis Laboratories (BIOSAOS )
Obesity is a major risk factor for obstructive sleep apnea (OSA). However, OSA is still largely under diagnosed in patients with a high cardiovascular risk.
- Trial name
- BIOSAOS (NCT03861468)
- Testing
- Care pathway
- Where
- France
- Sponsor
- University Hospital, Grenoble
Postoperative Cognitive Dysfunction, Postoperative Delirium
Taking Brain Monitoring to the Next Level
This one arm clinical study will assess the impact of a goal directed therapy intervention, aiming at optimizing depth of anesthesia and intraoperative blood pressure on the incidence of postoperative cognitive dysfunction and…
- Conditions
- Postoperative Cognitive Dysfunction, Postoperative Delirium, Obstructive Sleep Apnea
- Trial name
- HDBRAIN (NCT04246320)
- Testing
- Goal directed therapy (GDT)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of California, Los Angeles
Hypoxia, Sleep Apnea
Intermittent Hypoxia 2: Cardiovascular and Metabolism
The purpose of this study is to compare cardiovascular physiological adaptation to intermittent hypoxia (IH) of nonobese healthy subjects. The exposure will be two periods of two weeks (IH versus exposure "placebo hypoxia").
- Conditions
- Hypoxia, Sleep Apnea, Obstructive Sleep Apnea
- Trial name
- IH2 (NCT02058823)
- Testing
- Valsartan, Amlodipine
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Chronic Hypercapnic Respiratory Failure, Obesity Hypoventilation Syndrome
Efficacy of Average Volume Assured Pressure Support With Bi-Level Pressure Support Nocturnal Ventilation
Patients with chronic hypercapnic respiratory failure can be successfully treated with home nocturnal non-invasive ventilation. Bi-level pressure support ventilators are at present the most frequently used ventilators for long…
- Conditions
- Chronic Hypercapnic Respiratory Failure, Obesity Hypoventilation Syndrome, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT00479284
- Testing
- Average volume assured pressure support (AVAPS)
- Where
- Switzerland
- Volunteers
- 14 people
- Sponsor
- University Hospital, Geneva
Obstructive Sleep Apnea, Insulin Resistance
Endothelial Damage and Atherosclerosis in Obstructive Sleep Apnea
The investigators hypothesize that obstructive sleep apnea (OSA) may lead to increased formation/accumulation of advanced glycation ends (AGEs), and that the increase in AGEs is contributed in part by increased insulin…
- Conditions
- Obstructive Sleep Apnea, Insulin Resistance, Endothelial Function, Oxidative Stress
- Trial name
- NCT00942643
- Testing
- CPAP machine
- Where
- Hong Kong
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Sleep Apnea, Obstructive, Excessive Daytime Sleepiness
A Twelve-week, Double-blind, Placebo-controlled, Randomized, Parallel-group, Multicenter Study to Evaluate the Efficacy and Safety of Solriamfetol in the Treatment of Excessive Daytime Sleepiness (EDS) in Patients with Obstructive Sleep Apnea (OSA)
The purpose of this study is to evaluate the efficacy and safety of 12-week solriamfetol administration in the treatment of EDS in patients with OSA from China, using a randomized, double-blind, placebo-controlled, multi-center…
- Trial name
- NCT06103825
- Testing
- Solriamfetol
- Where
- 26 sites in China
- Volunteers
- 204 people
- Sponsor
- Ignis Therapeutics (Suzhou) Limited
Sleep Apnea
Evaluation of Obstructive Sleep Apnea With Long Range 3D Endoscopic Fourier Domain Optical Coherence Tomography (FDOCT)
The purpose of this study is to determine whether the Optical coherence tomography (OCT) can image the structure and geometry of hollow organs of the upper airway in sleep disorder.
- Trial name
- NCT01485497
- Testing
- 3D endoscopic Fourier Domain OCT
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Obstructive Sleep Apnea
A Study of Myofunctional Therapy After Sleep Apnea Surgery
Obstructive sleep apnea (OSA) is a common disorder characterized by recurrent upper airway collapse. While surgery is a common treatment, its success rates are variable.
- Trial name
- MFT-OSA (NCT07231224)
- Testing
- myofunctional therapy
- Where
- Taiwan
- Volunteers
- 51 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Melanoma With a Breslow's Thickness ≥ 1mm, Obstructive Sleep Apnea Syndrome
Impact of Obstructive SAS on Metastatic Potential of Cutaneous Melanoma
Hypothesis: to address if diagnosis of obstructive sleep apnea before or during the extending check-up is a risk factor toward metastasis for melanoma stage ≥ tIIaN0M0 Study design: Adult patients with a Breslow's Thickness ≥ 1mm…
- Trial name
- MELA-SAS (NCT02699918)
- Testing
- nocturnal oximetry
- Where
- France
- Sponsor
- AGIR à Dom
Obstructive Sleep Apnea, Secondary Hypertension
Obstructive Sleep Apnea and Endothelial Function in Patients With Resistant Hypertension
The purpose of this study is to determine the prevalence of obstructive sleep apnea and associate it with the endothelial function behavior in patients with resistant hypertension.
- Trial name
- NCT01854190
- Testing
- WatchPAT
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Rio de Janeiro State University
Sleep Apnea
Addressing Insufficient PAP Use in Older Veterans
Obstructive sleep apnea (OSA) is a common problem among middle-aged and older Veterans that is associated with poor nighttime sleep, more daytime sleepiness, poor functioning and worse quality of life.
- Trial name
- NCT04868682
- Testing
- PAP Adherence Program, Active Control
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- VA Office of Research and Development
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.