Clinical trials: Obstructive Chronic Pulmonary Disease
Pulmonary Disease, Chronic Obstructive
Acute Exacerbation of Chronic Obstructive Pulmonary Disease Inpatient Registry Study Stage II
The aim of this study is to provide high quality data and give a comprehensive overview of characteristics, clinical features, management and prognosis during exacerbations and stable periods among inpatients with acute…
- Trial name
- NCT05032898
- Volunteers
- 1,500 people
- Sponsor
- China-Japan Friendship Hospital
Chronic Obstructive Pulmonary Disease, Exacerbations
Micro-environment Involvement in Muscle Alteration Induced
Chronic Obstructive Pulmonary Disease (COPD) is characterized by persistent airway obstruction and inflammatory response of the lungs and bronchi.
- Conditions
- Chronic Obstructive Pulmonary Disease, Exacerbations, Skeletal Muscle Atrophy
- Trial name
- MicAMI-BPCO (NCT04448626)
- Where
- France
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Stroke, Upper Extremity Paresis
Functional Recovery in Stroke Patients With Task-Specific Robot-Aided Arm Therapy
The goal of this study is to determine whether task-oriented, robot-aided therapy is more effective than conventional physical and occupational therapy at promoting functional recovery of the affected arm in chronic hemiparetic…
- Trial name
- NCT00719433
- Testing
- robot therapy (ARMin), conventional therapy
- Where
- Switzerland
- Volunteers
- 76 people
- Sponsor
- University of Zurich
COPD
Effects of Ramadan Observance in Male Patients With Chronic Obstructive Pulmonary Disease
Purpose: To analyze the effects of Ramadan observance (RO) on pulmonary variables, exercise performance and postural balance in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT03604952
- Testing
- COPD patients
- Where
- Tunisia
- Volunteers
- 20 people
- Sponsor
- Faculty of Medicine, Sousse
COPD
Effect of Exercise Training on Salivary Immunoglobulin A in Patients With Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine whether whole body exercise training alters the immunity in the lungs of people with COPD and reduces the incidence of chest infections over the longer term.
- Trial name
- NCT04604717
- Testing
- Pulmonary rehabilitation
- Where
- 2 sites in Australia
- Volunteers
- 35 people
- Sponsor
- Bayside Health
COPD, HIV Infections
Airway Microbiome and Th17-mediated Inflammation in COPD Among HIV-infected Individuals in a Rural Ugandan Cohort
Rationale: COPD is increasing in prevalence among people living with HIV/AIDS (PLWHA) as widespread use of ART has increased longevity in this population. In rural Ugandan ART clinics, we report COPD prevalence of 6.22%.
- Conditions
- COPD, HIV Infections, Respiratory Disease
- Trial name
- HLM (NCT05223114)
- Testing
- Not applicable (N/A)
- Where
- Uganda
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Makerere University
Chronic Obstructive Pulmonary Disease
The Effectiveness of an Innovative Inhalation Training Device in Improving Medication Accuracy, Dyspnea, and Quality of Life in Elderly Patients With Chronic Obstructive Pulmonary Disease
This study aims to evaluate the effectiveness of an innovative inhaler training device, "Golden Rhino" (pMDI Practice Tool), in improving inhalation technique accuracy, dyspnea severity, and quality of life among elderly patients…
- Trial name
- pMDII (NCT07305649)
- Testing
- Innovative Inhaler Training Device (金犀利), Standard pMDI Inhaler Education
- Where
- Taiwan
- Volunteers
- 82 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
COPD (Chronic Obstructive Pulmonary Disease)
The Study of Chronic Obstructive Pulmonary Disease (COPD) Participants Treated With Dupilumab (STRIDE) Registry
The STRIDE Registry will evaluate the real-world effectiveness and safety of dupilumab in participants with COPD. The primary objective is to describe characteristics of participants newly initiated with dupilumab for COPD.
- Trial name
- STRIDE (NCT07612878)
- Testing
- Cohort 1: Dupilumab, Cohort 2: usual care only
- Where
- 7 sites in United States
- Volunteers
- 350 people
- Sponsor
- Sanofi
Pulmonary Disease, Chronic Obstructive
Evaluating the Clinical Effectiveness of a Patient-specific Silicone Stent
The goal of the trial is to establish a method, material, and patient-specific stent design that will last longer, fit better, and cause less trauma to the airway and the patient.
- Trial name
- NCT05050591
- Testing
- Patient-Specific Silicone Airway Stent
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- VisionAir Solutions
Pulmonary Disease, Chronic Obstructive
Ba253BINEB Compared to Ba253MDI (Metered Dose Inhaler) in Patients With Chronic Obstructive Pulmonary Disease (COPD)
The objective of this study is to investigate the efficacy and safety of Ba253BINEB during the continuous 4 weeks administration to the patients with COPD using Ba253MDI (Tersigan® aerosol) as the comparator drug.
- Trial name
- NCT02182583
- Testing
- Ba253MDI, Ba253BINEB
- Volunteers
- 163 people
- Sponsor
- Boehringer Ingelheim
COPD, Microbial Colonization
Partially Hydrolyzed Guar Gum (PHGG) for Amelioration of Chronic Obstructive Pulmonary Disease (COPD)
Some components of the diet could promote the growth of certain bacterial strains present in the intestine, which are closely associated with benefits for host health.
- Conditions
- COPD, Microbial Colonization, Respiratory Tract Disease
- Trial name
- NCT05126654
- Testing
- Partially Hydrolyzed Guar Gum (PHGG)
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fu Jen Catholic University Hospital
COPD, Arrhythmia
Perry Virtual - A Prospective and Observational Rural Health Trial
The principal objective of the study is to determine if patient-empowered, real-time and home- based patient monitoring of vital parameters can lead to: Reduction in admission rates and improved clinical management of chronically…
- Conditions
- COPD, Arrhythmia, Murmur, Heart, Chronic Disease
- Trial name
- NCT04483154
- Testing
- Coala Heart Monitor
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Coala Life, Inc
Smokers, Chronic Obstructive Pulmonary Disease
Incident Chronic Obstructive pulmoNary dIsease Cohort Study (ICONIC)
Chronic Obstructive Pulmonary Disease (COPD), , secondary to smoking, is a major public health issue with very high direct and indirect costs.
- Trial name
- ICONIC (NCT04252781)
- Testing
- Exhaustive exploration
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Obstructive Pulmonary Disease (COPD)
Improving Medication Management in COPD
A pilot trial to examine feasibility of a pharmacist-led intervention for patients with COPD (Chronic Obstructive Pulmonary Disease) and multimorbidity to improve medication safety and reduce dyspnea.
- Trial name
- NCT07453719
- Testing
- Pharmacist-led Medication Management Intervention
- Volunteers
- 92 people
- Sponsor
- Duke University
Coronary Artery Disease, Chronic Obstructive Pulmonary Disease
Inflammatory Biomarkers Predict Pulmonary Outcomes in Coronary Artery Bypass Grafting
The primary objective of this pilot study is to identify and quantify inflammatory and genetic markers from bronchoalveolar lavage fluid (BALF) and serum in patients with a history of chronic obstructive pulmonary disease (COPD)…
- Trial name
- CABG BALF (NCT01366469)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Pulmonary Disease, Chronic Obstructive
A Study To Assess Single Dosage Strength Of GW685698/GW642444 Chronic Obstructive Pulmonary Disease (COPD)
The purpose of this study is to assess the safety and efficacy of a single dosage strength of GW685698/GW642444 in subjects with Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- NCT00731822
- Testing
- GW685698/GW642444
- Where
- 9 sites in Norway, Sweden
- Volunteers
- 60 people
- Sponsor
- GlaxoSmithKline
Pulmonary Emphysema
Clinical Study to Evaluate the Exercise Capacity in Patients With Severe Emphysema Treated With Coils
The study hypothesis is that patients with homogeneous emphysema behave differently compared to heterogeneous emphysema with respect to exercise capacity.
- Trial name
- CYCLONE (NCT02879331)
- Testing
- 10 coils in upper lobes, 15 coils in upper and lower lobes, cycloergometry
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Pulmonary Disease, Chronic Obstructive
Combined Bronchodilators in Chronic Obstructive Pulmonary Disease and the Risk of Adverse Cardio-pulmonary Events
Background: Recent observational studies have reported possible arrhythmogenic effects with long-acting beta-agonists (LABA), while the long-acting anticholinergic tiotropium has been associated with cardiovascular and…
- Trial name
- NCT02096731
- Where
- Canada
- Volunteers
- 115,397 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease
Foster® pMDI (CHF 1535) Versus Symbicort® Turbohaler in COPD Patient (FORSYYN)
Primary Objective To demonstrate that CHF 1535 pMDI is non-inferior to Symbicort® Turbohaler® in terms of pulmonary function (change from baseline in pre-dose morning FEV1 at Week 24) in patients with COPD.
- Trial name
- FORSYYN (NCT03888131)
- Where
- 53 sites in China
- Volunteers
- 750 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Chronic Heart Failure, Diabetes Mellitus
Exploring Acceptance and Outcomes of an Online-based Self-management Support System in Chronic Illness
The aim of the USECARE project is to improve and test SENACA, an ICT-based self-management support system for chronically ill patients and informal caregivers. 60 end-users will be instructed to use SENACA for approx.
- Conditions
- Chronic Heart Failure, Diabetes Mellitus, Chronic Obstructive Pulmonary Disease, Special Orthopaedic Co-Morbidity After Hip/Knee Replacement
- Trial name
- USECARE (NCT02832739)
- Testing
- SENACA - ICT based self-management support system
- Where
- 2 sites in Israel, Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assuta Medical Center
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