Clinical trials: Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)
Obstructive Sleep Apnea (OSA)
Patient-Perceived Symptoms at the Center of Obstructive Sleep Apnea (OSA) Management: Validation of the French Version of the Patient-Reported Apnea Questionnaire (PRAQ)
Obstructive sleep apnea (OSA) is a common and disabling sleep disorder in which the assessment and monitoring of symptoms are central to patient management.
- Trial name
- PRAQ (NCT07836062)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Bordeaux
Obstructive Sleep Apnea
A Study for Obstructive Sleep Apnea Using a New At-Home Sleep Test
The purpose of the study is to test the workflow of an auto-titrating mandibular positioner in its intended setting. Participants with obstructive sleep apnea will use the device to determine their eligibility for oral appliance…
- Trial name
- NCT03049982
- Testing
- Auto-titrating mandibular positioner test
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Zephyr Sleep Technologies
Obstructive Sleep Apnea Syndrome
Study of Acceptability and Tolerance of an Orofacial Myofunctional Rehabilitation Pacifier in Infants
The development of the medical device tested was inspired by palatal plates used to treat myofunctional disorders in young patients with Down syndrome.
- Trial name
- YooTET (NCT06489223)
- Testing
- Orofacial Myofunctional Rehabilitation Pacifier
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Obstructive Sleep Apnea
BASET Scoring: A Novel Simple Biometric Score and Potential Tool for Diagnosis and Grading of Obstructive Sleep Apnea Syndrome (OSAS) Patients
this study aims to assess the validity of BASET scoring as a new potential tool for diagnosis and grading the severity of OSAS patients and as screening of the risk factors of OSAS.
- Trial name
- BASET (NCT05511974)
- Testing
- BASET score
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Mansoura University
Obstructive Sleep Apnea Syndrome, Gut Microbiota
Intestinal Dysbiosis During Obstructive Sleep Apnea Syndrome
Obstructive Sleep Apnea Syndrome (OSA) is one of the most common chronic diseases and is associated with prognostic cardiovascular and metabolic co-morbidities.
- Trial name
- DYNAMIC (NCT04947410)
- Testing
- CPAP or nasal dilators
- Sponsor
- University Hospital, Grenoble
Obstructive Sleep Apnea
A Research Study for Children About Heart Changes and Obstructive Sleep Apnea (OSA)
In this research study the investigators want to learn more about the risk of developing blood vessel and heart disease from night-time sleep apnea.
- Trial name
- NCT01837459
- Where
- United States
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Obstructive Sleep Apnea, Cognitive Impairment
Prevalence of Obstructive Sleep Apnea (OSA) and the Association With Cognitive Impairment
The study is aimed to carry out an epidemiology study investigating the prevalence of obstructive sleep apnea (OSA) and the association with cognitive impairment.
- Trial name
- NCT04658290
- Where
- Hong Kong
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Narcolepsy, Obstructive Sleep Apnea
"A Long-Term Safety Study of JZP-110 in the Treatment of Excessive Sleepiness in Subjects With Narcolepsy or OSA"
This is a Phase 3 study to assess the long-term safety and maintenance of efficacy of JZP-110 in subjects who have completed Study 14-002, 14-003, 14-004, 15-004, 15-005, ADX-N05 201, or ADX-N05 202.
- Trial name
- NCT02348632
- Testing
- JZP-110
- Where
- 80 sites in United States, Canada and 4 more
- Volunteers
- 645 people
- Sponsor
- Jazz Pharmaceuticals
Obstructive Sleep Apnea (OSA), Ischemic Optic Neuropathy/Optic Nerve Stroke
Optic Nerve Injury in Obstructive Sleep Apnea Patients
Ischemic optic neuropathy (ION) is damage to the optic nerve caused by ischemia and hypoxia of the optic nerve due to an impairment of the blood supply to the optic nerve from the arteries.
- Trial name
- NCT06748703
- Testing
- CPAP Treatment
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Nanjing Medical University
Sleep Apnea, Obstructive
Combination Therapy to Treat Sleep Apnea
In Obstructive sleep apnea (OSA), the upper airway closes over and over again during sleep. This leads to disrupted sleep (waking up during the night), daytime sleepiness, and an increased risk for developing high blood pressure.
- Trial name
- NCT01633827
- Testing
- Sedative, Room air, Oxygen
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Brigham and Women's Hospital
Sleep Apnea, Obstructive, Diabetes Mellitus
Vascular Impairment in Type II Diabetes Mellitus With Co-morbid Obstructive Sleep Apnea
The investigators will examine the possible synergistic effects of obstructive sleep apnea (OSA) and type II diabetes mellitus (DM) on vascular functioning by performing a two-part investigation: A cross-sectional study comparing…
- Trial name
- NCT01629862
- Testing
- Continuous positive airway pressure
- Where
- 2 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Sanjay R Patel
Obstructive Sleep Apnea
Ambulatory Blood Pressure Control and Cognition in Patients With Obstructive Sleep Apnea (AMPLE)
To compare the blood pressure control and cognitive responses of three groups of patients: those diagnosed with Obstructive Sleep Apnea (OSA) and treated with Continuous Positive Airway Pressure (CPAP) for at least six months…
- Trial name
- AMPLE (NCT06463002)
- Testing
- Ambulatory blood pressure monitoring and Montreal Cognitive Assessment
- Where
- Singapore
- Volunteers
- 150 people
- Sponsor
- National University Hospital, Singapore
Obstructive Sleep Apnea
Efficacy and Stability of Dexmedetomidine Sedation Compared to Propofol Sedation in the Drug Induced Sleep Endoscopy
Obstructive Sleep Apnea Syndrome affect up 12% in adult population. It is associated with an increase rate of hypertension, metabolic syndrome, depression and adverse cardiovascular events.
- Trial name
- DISERT (NCT03892122)
- Testing
- Propofol Fresenius, Dexmedetomidine
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- Ospedale Monsignor R. Dimiccoli, Barletta
Obstructive Sleep Apnea
Sleep Apnea Video Education for CPAP (SAVE-CPAP)
The purpose of this study is to determine how satisfied patients are when undergoing an overnight polysomnogram (sleep study), what their knowledge about sleep apnea is, and what factors affect obstructive sleep apnea (OSA)…
- Trial name
- SAVE-CPAP (NCT02553694)
- Testing
- Enhanced education, Usual education, Usual follow up
- Where
- United States
- Volunteers
- 212 people
- Sponsor
- University of Chicago
Sleep Apnea, Obstructive Sleep Apnea
Effect on Sleep of Surgical Treatment of Severe Nasal Obstruction
The aim of the study is to evaluate the effect of nasal desobstruction surgery (septoplasty, septorhinoplasty or total ethmoidectomy) on sleep quality, assessed by the variation of the Wake after sleep onset (WASO), in patients…
- Conditions
- Sleep Apnea, Obstructive Sleep Apnea, Nasal Obstruction
- Trial name
- SOMNOSE (NCT05582070)
- Testing
- actigraphy
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Bordeaux
OSA
Obstructive Sleep Apnea Prevalence in Patients With Chronic Obstructive Pulmonary Diseases
The conjunction of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) is known as Overlap Syndrome (OS). The coexistence of these diseases have cardiovascular morbidity and mortality.
- Trial name
- NCT04903639
- Testing
- sleep study
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Obstructive Sleep Apnea
Usability Evaluation of Menai CPAP Masks
The primary objective of this study is to evaluate the subjective performance of the Menai mask systems (full face, nasal, and pillows variants), compared against Comparison mask systems.
- Trial name
- NCT02364375
- Testing
- Menai mask (full face), Menai Standard mask (full face), Menai mask (nasal)
- Where
- Australia
- Volunteers
- 30 people
- Sponsor
- ResMed
Apnea, Obstructive Sleep, Obstructive Sleep Apnea
OSA-18 in Children With Mild Obstructive Sleep Apnea: Can it be a Helpful Decision Making Tool?
The concept is a novel research idea that incorporates the potential impact of patient quality of life (QOL) on decision-making for treatment of mild obstructive sleep apnea (OSA).
- Trial name
- OSA-18 (NCT05911646)
- Testing
- OSA-18 Survey, Decisional Conflict (DCS)
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Connecticut Children's Medical Center
Obstructive Sleep Apnea
Evaluation of Acclimate Feature for Positive Airway Pressure (PAP) Therapy
The purpose of the study is to evaluate if using the Acclimate feature at the beginning of Positive Airway Pressure (PAP) therapy results in patients using their PAP therapy at least as long as they would standard therapy.
- Trial name
- NCT01421654
- Testing
- S9 Elite with Acclimate, S9 Elite
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- ResMed
Obstructive Sleep Apnea
Assessment of OSA in Latin American and Response to Neuromod Therapy
The purpose of this study is to characterize the upper airway of Latin American subjects who have been diagnosed with moderate/severe obstructive sleep apnea (OSA) and assess response to a neuromodulation therapy to treat OSA.
- Trial name
- Trans-Q DISE (NCT06762873)
- Testing
- Drug Induced Sleep Endoscopy with PNS
- Where
- Paraguay
- Volunteers
- 50 people
- Sponsor
- Lunair Medical
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