Clinical trials: Obstructive Sleep Apnea-Hypopnea Syndrome
PTSD, Sleep
Effects of CPAP Therapy on PTSD Symptoms
The purpose of this study is to evaluate the effects of treating Obstructive Sleep Apnea (OSA) with continuous positive airway pressure (CPAP) therapy on symptoms of post traumatic stress disorder (PTSD).
- Conditions
- PTSD, Sleep, Obstructive Sleep Apnea, Quality of Life
- Trial name
- NCT02019914
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Veterans Medical Research Foundation
Sleep Apnea Syndrome, Polygraphy
Sleep Apnea Syndrome and Community Acquired Pneumonia
The association of sleep apnea-hypopnea syndrome (SAHS) with the infections of the lower airway has not been studied. The aspiration of secretions of the upper airway and the colonization by microorganisms is considered a main…
- Conditions
- Sleep Apnea Syndrome, Polygraphy, Community Acquired Pneumonia, Infections
- Trial name
- NEBULOSA (NCT01071421)
- Testing
- abbreviated polysomnography
- Where
- Spain
- Volunteers
- 123 people
- Sponsor
- Hospital Universitario San Juan de Alicante
Obstructive Sleep Apnea, Sleep Position Trainer
RCT: Oral Appliance Therapy and Sleep Position Trainer in Patients With Position Dependant Obstructive Sleep Apnea
SUMMARY Rationale: Fifty-six percent of patients with Obstructive Sleep Apnea (OSA) are position dependent, defined as having an AHI, which is at least twice as high in supine sleeping position compared to the AHI during sleep in…
- Conditions
- Obstructive Sleep Apnea, Sleep Position Trainer, Oral Appliance Therapy
- Trial name
- POSA (NCT02045576)
- Testing
- sleep position trainer, Oral Appliance Therapy
- Where
- 2 sites in Netherlands
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Obstructive Sleep Apnea
CAP Pilot Study for Obstructive Sleep Apnea (OSA)
This is a pilot to review the feasibility of a program that assists patients towards therapy compliance by scheduled intervention through the first month of therapy.
- Trial name
- NCT02309749
- Testing
- CAP
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea
Ezopiclone Improves the Quality of Overnight Polysomnography
Patients often have difficulty sleeping during overnight sleep testing in a lab environment. The purpose of this study is to determine if taking a sleep aid will improve sleep and therefore the quality of the sleep study.
- Trial name
- NCT00507117
- Testing
- Lunesta
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Sleep Apnea - Obstructive
A Study of the Sleepnet Elara APAP Device
The goal of this study is to evaluate the effectiveness of the Elara APAP device.
- Trial name
- NCT07559708
- Testing
- Sleepnet Elara Treatment
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- Sleepnet Corporation
Obstructive Sleep Apnea
Evaluation of Treatment Efficacy of a Modified Positive Airway Pressure Device to Treat Obstructive Sleep Apnea
This study will investigate the efficacy of the FPH modified positive airway pressure (PAP) device with or without SensAwake; and with different pressure support in OSA participants; in both an in-home and in-lab environment.
- Trial name
- NCT02971436
- Testing
- FPH Device with SensAwake On + Pressure Support A, FPH Device with SensAwake Off + Pressure Support A, FPH Device with SensAwake On + Pressure Support B
- Where
- 2 sites in New Zealand
- Volunteers
- 29 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea
MicroRNAs as Biomarkers for Obstructive Sleep Apnea
Although obstructive sleep apnea (OSA) is a common disorder, there are no blood biomarkers for identification and management of these patients.
- Trial name
- MIR-OSA (NCT06189755)
- Testing
- Positive Airway Pressure
- Where
- 3 sites in United States, Iceland
- Volunteers
- 500 people
- Sponsor
- University of Pennsylvania
Sleep Apnea, Dyslipidemias
CPAP Effect on Lipid Profile and Hyperuricemia in Patients With Dyslipidemia and Moderate-severe Obstructive Sleep Apnea
Clinical Trial Phase IV Indication: Moderate-severe obstructive sleep apnea and dyslipidemia. Objectives: Main objective: To test whether 12 months of CPAP treatment associated with conventional pharmacological treatment improves…
- Conditions
- Sleep Apnea, Dyslipidemias, Hyperuricemia
- Trial name
- CPAPLIP (NCT06463561)
- Testing
- Continuous positive airway pressure, Hygienic-dietary recommendations and daily physical activity promotion
- Where
- Spain
- Volunteers
- 220 people
- Sponsor
- Hospital Universitario La Paz
Insomnia, Obstructive Sleep Apnea
Treatment of Insomnia in Elderly Sleep Apnea Patients With Ramelteon (TAK 375)
The objective of the study is to determine if treatment with Ramelteon will help to improve insomnia in older adults with co-existent insomnia and sleep apnea. The primary study objective is sleep latency (a measure of insomnia).
- Trial name
- NCT01048242
- Testing
- rozerem
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Pennsylvania
Obstructive Sleep Apnea
Masked Hypertension in Patients With Obstructive Sleep Apnoea
Assessment of the possible difference in masked hypertension prevalence when it is evaluated by automated office blood pressure measurement (AOBPM) instead of office blood pressure measurement (OBPM) in patients with obstructive…
- Trial name
- NCT03869125
- Testing
- Blood pressure measurement
- Where
- Czechia
- Volunteers
- 65 people
- Sponsor
- University Hospital Olomouc
Obstructive Sleep Apnea, Pregnancy
Positive Airway Pressure, Sleep Apnea, and the Placenta (PAP-SAP)
This study is testing the hypothesis of whether continuous positive airway pressure (CPAP) therapy improves placental histopathology and secretory function.
- Conditions
- Obstructive Sleep Apnea, Pregnancy, Obesity, Preeclampsia
- Trial name
- PAP-SAP (NCT02412696)
- Testing
- Positive Airway Pressure, Nasal Dilator Strips
- Where
- United States
- Volunteers
- 262 people
- Sponsor
- The Miriam Hospital
Obstructive Sleep Apnea, Muscle Disorder
Effects of Newly-created Individualized Upper Airway Muscle Functional Training on Patients With OSA
Objectives: To observe the effect of newly-created individualized upper airway muscle functional training on the condition and intraday symptoms of OSA patients; to study the effect of this training method on the excitability of…
- Trial name
- NCT05346705
- Testing
- New individualized upper airway muscle functional training
- Where
- China
- Volunteers
- 300 people
- Sponsor
- First Hospital of China Medical University
Obstructive Sleep Apnea
Pediatric Nasal Mask Usability Study
The purpose of the study is to demonstrate the effectiveness of a pediatric mask in treating obstructive sleep apnea (OSA) in a pediatric population.
- Trial name
- NCT01154322
- Testing
- Pixi pediatric mask
- Where
- 3 sites in United States
- Volunteers
- 16 people
- Sponsor
- ResMed
Sleep-Disordered Breathing, Sleep Architecture
Belun Ring Platform With an Improved Algorithm for OSA Assessment
OSA is commonly diagnosed with either attended in-lab polysomnography (PSG) or unattended home sleep apnea testing (HSAT). The BLS-100 (Belun Technology Company Limited, Hong Kong) is a novel neural network-based HSAT platform…
- Trial name
- NCT04885062
- Testing
- Belun Ring, PSG
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Belun Technology Company Limited
Sleep Apnea, Obstructive Sleep Apnea
Effect on Sleep of Surgical Treatment of Severe Nasal Obstruction
The aim of the study is to evaluate the effect of nasal desobstruction surgery (septoplasty, septorhinoplasty or total ethmoidectomy) on sleep quality, assessed by the variation of the Wake after sleep onset (WASO), in patients…
- Conditions
- Sleep Apnea, Obstructive Sleep Apnea, Nasal Obstruction
- Trial name
- SOMNOSE (NCT05582070)
- Testing
- actigraphy
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Bordeaux
Obstructive Sleep Apnea
Obstructive Sleep Apnea in the Absence of Metabolic Syndrome
Obstructive Sleep Apnea (OSA) is commonly associated with factors that increase cardiovascular risk, including Metabolic Syndrome (MS).
- Trial name
- NCT01635010
- Testing
- continuous positive airway pressure (CPAP)
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Obstructive Sleep Apnea
Predictive Analytics and Peer-Driven Intervention for Guideline-based Care for Sleep Apnea
Obstructive sleep apnea (OSA) is a prevalent condition that affects 7 to 12% of the US population and is characterized by repetitive collapse of the upper airway during sleep.
- Trial name
- NCT03345524
- Testing
- Peer-Buddy System, Usual Care
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- University of Arizona
Sleep Apnea, Obstructive
The Advance Trial. Tongue Advancement for Obstructive Sleep Apnea: An Evaluation of the Aspire Medical Advance System
The objective of the study is to assess the effectiveness of the Aspire Medical Advance System in obstructive sleep apnea by demonstrating a statistically significant mean reduction in the apnea-hypopnea index (AHI) from baseline…
- Trial name
- NCT00467324
- Testing
- Aspire Medical Advance System
- Where
- 4 sites in United States
- Volunteers
- 42 people
- Sponsor
- Aspire Medical
Sleep Apnea, Overweight and Obesity
CPAP, Nutrition & Exercise Against Sleep Apnea
This study evaluates the addition of a comprehensive lifestyle program including dietary management and exercise to continuous positive airway pressure (CPAP) therapy in overweighted adults with obstructive sleep apnea.
- Trial name
- TINE (NCT03959280)
- Testing
- Tailored intervention, Control
- Where
- 2 sites in France, Switzerland
- Volunteers
- 120 people
- Sponsor
- Raphael Heinzer