Clinical trials: Obstructive Sleep Apnea-hypopnea Syndrome
Obstructive Sleep Apnea, Obesity
Obesity and Obstructive Sleep Apnea (OSA) in Children
The goal of this research is to study the prevalence of sleep disordered breathing and associated morbidity in obese children and to examine the role of diet and physical activity in the treatment of sleep-disordered breathing in…
- Trial name
- NCT01135147
- Testing
- Diet, Surgery
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Bruxism, Temporomandibular Joint Disorders
Aspects Associated With Obstructive Sleep Apnea, Bruxism and Orofacial Pain
This study evaluated the influence of the sleep bruxism (SB), awake bruxism (AB) and obstructive sleep apnea syndrome (OSAS) on the signs and symptoms of temporomandibular disorders (TMD).
- Conditions
- Bruxism, Temporomandibular Joint Disorders, Obstructive Sleep Apnea Syndrome
- Trial name
- NCT03766464
- Testing
- Evaluation of TMD and pain sensitivity, Evaluation of SB, Evaluation of AB
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Apnea, Sleep
Remifentanil in Adults With OSA
Obstructive Sleep Apnea (OSA) is the most common problem that affects sleep. People with this problem have their airway blocked or minimized, causing snoring or gasping while sleeping.
- Trial name
- AROSA (NCT02898792)
- Testing
- Targeted infusion of remifentanil
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obstructive Sleep Apnea
Exercise Intolerance in Obstructive Sleep Apnea Syndrome Patients
The syndrome of obstructive sleep apnea (OSAS) is a public health problem that affects 2 to 4% of the general population. The patients with OSAS frequently complain of intolerance to exercise muscle fatigue and a significant even…
- Trial name
- EXAOS (NCT00837018)
- Testing
- physical exercise program
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Ehler's Danlos Syndrome, Obstructive Sleep Apnea
Obstructive Sleep Apnoea in Children and Adolescents With Ehlers-Danlos Syndrome
Ehlers-Danlos Syndrome (EDS) is a clinically and genetically heterogeneous group of inherited connective tissue disorders characterized by joint hypermobility, skin hyperextensibility, and tissue fragility.
- Trial name
- NCT02712060
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Obstructive Sleep Apnea
Field Usability Study of Eclipse Mask
The study is designed to assess the usability of a novel CPAP human interface compared to a traditional nasal mask. Human subjects will interact with two different CPAP interfaces including a traditional CPAP mask and the 2nd…
- Trial name
- NCT05559047
- Testing
- Eclipse mask
- Where
- 3 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bleep, LLC
Chronic Rhinosinusitis (Diagnosis), Nasal Polyps
NO Measurements in Screening for Asthma and OSA, in Patients With CRSwNP
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a condition resulting in varying degrees of nasal congestion, nasal secretion, facial pain and reduced or absent sense of smell.
- Conditions
- Chronic Rhinosinusitis (Diagnosis), Nasal Polyps, Asthma, Obstructive Sleep Apnea
- Trial name
- NCT03963648
- Testing
- Fractioned Exhaled Nitrogen Oxide measurements
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Christian von Buchwald
Sleep Apnea, Glucose Metabolism Disorders
Obstructive Sleep Apnea and Glucose Metabolism
Many adults who are overweight have obstructive sleep apnea (OSA) which disrupts sleep and makes it difficult to breath during the night. OSA increases the risk for a person to become insulin resistant and diabetic.
- Trial name
- OSAGM (NCT03408613)
- Testing
- Positive Airway Pressure, Supplemental Oxygen
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Obstructive Sleep Apnea
TipTraQ Home Sleep Test Validation Study, VGH
A validation study has been designed to assess the performance of a home sleep test device, TipTraQ, for screening sleep apnea. The study involves participants wearing the TipTraQ device on their fingertip during a traditional…
- Trial name
- NCT06474390
- Where
- Taiwan
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- PranaQ Pte. Ltd.
OSAHS, Gastrointestinal Endoscopy
Observation of Clinical Effect of New Oropharyngeal Airway in Patients With OSHAS During Painless Gastroenteroscopy
the(obstructivesleepapneahypoapneasyndromeOSAHS) is a kind of to sleep appear periodically in the process of syndrome characterized by partial or complete obstruction of upper respiratory tract.Patients with obstruction during…
- Conditions
- OSAHS, Gastrointestinal Endoscopy, Airway Complication of Anesthesia
- Trial name
- NCT06594380
- Testing
- Group using new oropharyngeal airway (experimental group), Endoscopic bite group (control group)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Jianbo Wu
Obstructive Sleep Apnea, Snoring
A Disposable Device NAS to Treat Obstructive Sleep Apnea and Snoring
The purpose of this research study is to test a new approach for treating patients with obstructive sleep apnea and/or snoring. The new nasal device, nastent (NAS: nasal airway stent), appears to be a useful alternative or…
- Trial name
- NCT02928770
- Testing
- Nastent
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obstructive Sleep Apnea
Fentanyl Test in Children's Adenotonsillectomy
The purpose of this study is to discuss the relationship between the result of fentanyl test and required dosage of morphine for children with OSAS after adenotonsillectomy；and to evaluate the ability of predicting requested…
- Trial name
- NCT02484222
- Testing
- Fentanyl
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Obstructive Sleep Apnoea (OSA), Hypoventilation Syndrome
Sleep-disordered Breathing Database
The goal of this study is to collect clinical data on patients who have had a sleep study and are given a diagnosis of a sleep related breathing disorder such as obstructive sleep apnoea.
- Trial name
- NCT07402603
- Where
- United Kingdom
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Obstructive Sleep Apnea, PTSD
Cognitive Behavioral Therapy to Increase CPAP Adherence in Veterans With PTSD
Approximately 20 million Americans suffer from Obstructive Sleep Apnea (OSA) creating risks for major health problems, including dementia, heart attack, and stroke.
- Conditions
- Obstructive Sleep Apnea, PTSD, Posttraumatic Stress Disorder
- Trial name
- NCT02641496
- Testing
- CBT-OSA, Sleep Education
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Obstructive Sleep Apnea Syndrome
Validation of Sleep Monitoring Algorithm Based on Smart Watches
In recent years, wearable devices are booming to enable not only the health monitoring but also the sleep efficiency assessment.
- Trial name
- NCT06696196
- Testing
- smart watches(wearable devices)
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Obstructive Sleep Apnoea, Open Angle Glaucoma
Prevalence of Obstructive Sleep Apnoea in Glaucoma
This study aims to investigate a potential link between Obstructive Sleep Apnoea (OSA) and Open Angle Glaucoma (OAG); initially by determining whether the prevalence of OSA is higher in patients with OAG in comparison to people…
- Trial name
- POSAG (NCT02713152)
- Where
- United Kingdom
- Volunteers
- 403 people, healthy volunteers welcome
- Sponsor
- Papworth Hospital NHS Foundation Trust
Obstructive Sleep Apnea
Rapid Maxillary Expansion for Residual Pediatric
Randomized Controlled Trial comparing Rapid Maxillary Expansion with Standard Clinical Practice in patients with residual pediatric Obstructive Sleep Apnea Syndrome after adenotonsillectomy.
- Trial name
- ERMES (NCT02947464)
- Testing
- Standard clinical practice, Standard clinical practice + Rapid Maxillary Expansion
- Where
- Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Basque Health Service
Sleep Apnea Syndromes
Effect of Compression Stockings on the Number of Apneas/Hypopneas Per Hour of Sleep in Patients With Syndrome Obstructive Sleep Apnea/Hypopnea as Compared to no Treatment
The sleep apnea-hypopnea syndrome is characterized by the occurrence, during sleep, of abnormally frequent episodes of interruption of ventilation (apnea), or significant reduction in ventilation (hypopnea).
- Trial name
- NCT05477719
- Testing
- Wearing of specific compression stockings
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Sigvaris France
Velopharyngeal Insufficiency, Swallowing
Velopharyngeal Insufficiency After Maxillomandibular Advancement Osteotomy in Obstructive Sleep Apnea Patients
The aim of this study is to gain insight into the development of velopharyngeal insufficiency (VPI) in patients who have undergone maxillomandibular advancement osteotomy (MMA) as a treatment for obstructive sleep apnea syndrome…
- Conditions
- Velopharyngeal Insufficiency, Swallowing, Nasality, Speech
- Trial name
- VPIMMA (NCT07301021)
- Where
- Netherlands
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Obstructive Sleep Apnea, Hypertension
Effect of Selective and Nonselective Cyclooxygenase Enzyme Inhibition on Arterial Blood Pressure and Cerebral Blood Flow With Exposure to Intermittent Hypoxia in Humans
The study has been designed to assess the effect of cyclooxygenase inhibition on blood pressure, cerebral blood flow, ventilation and renal hemodynamics following chronic intermittent hypoxia exposure.
- Conditions
- Obstructive Sleep Apnea, Hypertension, Cardiovascular Diseases, Stroke
- Trial name
- NCT01280006
- Testing
- Intermittent hypoxia, Indomethacin, Celecoxib
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Calgary