Clinical trials: Obstructive Sleep Apnoea Hypopnoea Syndrome
Arterial Hypertension
"Escape" Phenomenon of the Antihypertensive Therapy Efficacy
A little attention is paid to the AHT efficacy escaping problem, which can be explained by the AHT correction simplicity and rapid achievement of the target BP level.
- Trial name
- ESCAPE (NCT05436730)
- Testing
- Ambulatory blood pressure measurement device, Sphygmocor, VaSera-VS
- Where
- Russia
- Volunteers
- 165 people
- Sponsor
- Federal State Budgetary Institution NATIONAL MEDICAL RESEARCH CENTRE OF CARDIOLOGY NAMED AFTER ACADE
Obstructive Sleep Apnea
Effect of Upper Airway Stimulation in Patients With Obstructive Sleep Apnea
Upper Airway Stimulation is a new therapy, which is available for patients with obstructive sleep apnea, who are non-compliant to the standard treatment continuous positive airway pressure (CPAP) therapy.
- Trial name
- EFFECT (NCT03760328)
- Testing
- Upper Airway Stimulation
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Technical University of Munich
Obstructive Sleep Apnea
Continuous Positive Airway Pressure (CPAP), Oral Appliance and Physical Exercise in the Obstructive Sleep Apnea
Introduction: It is unclear whether exercise training with or without Continuous Positive Airway Pressure (CPAP) and Oral Appliance (OA) is more effective in reducing symptoms of Obstructive Sleep Apnea (OSA) than treatment…
- Trial name
- NCT01289392
- Testing
- Continuous Positive Airway Pressure (CPAP), Oral Appliance (OA), Physical Exercise
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Obstructive Sleep Apnea
Comparison Between Auto CPAP and Fixed CPAP in Chinese Patients With OSA
AutoCPAP would lead to better compliance than FixCPAP
- Trial name
- NCT00307424
- Testing
- AutoCPAP, FixCPAP
- Where
- 2 sites in China
- Sponsor
- Chinese University of Hong Kong
Obstructive Sleep Apnea (OSAS)
Night Balance for Positional Obstructive Sleep Apnea Syndrome (POSAS)
POSAS can be treated with CPAP however there is now evidence from a few studies that Night Balance is effective in POSAS. Night Balance seems to be better accepted than CPAP so we would like to examine if we could find similar…
- Trial name
- POSAS (NCT02114424)
- Testing
- Positional vibrator belt
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Snoring, Obstructive Sleep Apnea
Smart Pillows for Enhancing Sleep Quality
The purpose of this study is to examine the impact of smart pillows on the sleep quality of individuals who experience a snoring issue and/or obstructive sleep apnea (OSA), as well as their sleep partners.
- Trial name
- NCT06594627
- Testing
- Smart pillow
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Indiana University
Obstructive Sleep Apnea
Stellate Ganglion Block in Obstructive Sleep Apnea
The goal of this clinical trial is to test the efficacy of stellate ganglion block in Obstructive Sleep Apnea. The main question it aims to answer are: Can stellate ganglion block improve Obstructive Sleep Apnea? Patients were…
- Trial name
- NCT06249490
- Testing
- routine rehabilitation treatment, Stellate ganglion block, Lidocaine Hydrochloride Injection
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Zeng Changhao
Obstructive Sleep Apnea
Measurement of Critical Closing Pressure (Pcrit) During Drug-Induced Sleep Endoscopy (DISE)
This study intends to test the feasibility of measurement of the critical closing pressure (Pcrit) during drug-induced sleep endoscopy (DISE) for use in future studies, which are aimed at finding an alternative method for patient…
- Trial name
- Pcrit-DISE (NCT04232410)
- Testing
- Drug induced sleep endoscopy, Measurement of critical closing pressure of the uppper airway
- Where
- Belgium
- Volunteers
- 13 people
- Sponsor
- University Hospital, Antwerp
Sleep-Disordered Breathing, Sleep Architecture
Validation of Belun Ring Gen3 Deep Learning Algorithms With Subxiphoid Body Sensor
Hypothesis: BR's Gen3 DL algorithms, combined with its subxiphoid body sensor, can accurately diagnose OSA, categorize its severity, identify REM OSA and supine OSA, and detect central sleep apnea (CSA).
- Conditions
- Sleep-Disordered Breathing, Sleep Architecture, Arrhythmia
- Trial name
- NCT06255613
- Testing
- Belun Ring, Belun Cor
- Where
- 2 sites in United States
- Volunteers
- 79 people
- Sponsor
- Belun Technology Company Limited
Obstructive Sleep Apnea, Snoring
Childhood Adenotonsillectomy Study for Children With OSAS
The purpose of this research is to determine the effect of adenotonsillectomy surgery (removal of tonsils and adenoids) on obstructive sleep apnea syndrome (OSAS) in children.
- Trial name
- CHAT (NCT00560859)
- Testing
- Adenotonsillectomy (AT) - removal of adenoids and tonsils, Watchful Waiting
- Where
- 6 sites in United States
- Volunteers
- 453 people
- Sponsor
- University of Pennsylvania
Postoperative Cognitive Dysfunction, Postoperative Delirium
Taking Brain Monitoring to the Next Level
This one arm clinical study will assess the impact of a goal directed therapy intervention, aiming at optimizing depth of anesthesia and intraoperative blood pressure on the incidence of postoperative cognitive dysfunction and…
- Conditions
- Postoperative Cognitive Dysfunction, Postoperative Delirium, Obstructive Sleep Apnea
- Trial name
- HDBRAIN (NCT04246320)
- Testing
- Goal directed therapy (GDT)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of California, Los Angeles
Obstructive Sleep Apnea, Acute Myocardial Infarction
Prospective Observational Registry for Obstructive Sleep Apnea in Patients With Acute Myocardial Infarction
Obstructive sleep apnea (OSA) has been known as a risk factor for coronary artery disease, heart failure, cerebrovascular accident and atrial fibrillation.
- Trial name
- OSAAMI (NCT03600246)
- Testing
- WATCH-PAT
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Wonju Severance Christian Hospital
Obstructive Sleep Apnea
Drug Induced Submental Ultrasound in Obstructive Sleep Apnea Patients
In this study, submental ultrasound during awake and simultaneous under Drug-induced sleep endoscopy is applied in the diagnostic workup of obstructive sleep apnea patients.
- Trial name
- NCT03285451
- Testing
- submental ultrasonography
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Obstructive Sleep Apnea
Aspirin Resistance in OSA Patients
Obstructive Sleep Apnea (OSA) patients are at increased risk of major cardiovascular events, so many patients take aspirin for prevention.
- Trial name
- NCT03930875
- Testing
- Aspirin Resistance testing
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Danbury Hospital
Snoring, Obstructive Sleep Apnea (OSA)
Validation of a Snoring App Against Commercially Available Applications and PSG
This study will compare the output of a new snoring application against another commercially available application and polysomnography (either home or in-laboratory).
- Trial name
- NCT07097597
- Testing
- Comparison 1: New Snoring Application, Comparison 2: Commercially Available Snoring Application, Comparison 3: Polysomnography
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Windsor Sleep Disorders Clinic
Obstructive Sleep Apnea
Validation of the Mutuality Scale in Patients With OSA and Their Partners
Main objective of this study is to assess the psychometric characteristics of the Mutuality Scale both in patients with Obstructive Sleep Apnea Syndrome (OSAS) and in their partners-The association between the mutuality score in…
- Trial name
- VAMOS (NCT05817123)
- Testing
- Questionnaires
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Istituto Auxologico Italiano
Obstructive Sleep Apnea Syndrome, Gut Microbiota
Intestinal Dysbiosis During Obstructive Sleep Apnea Syndrome
Obstructive Sleep Apnea Syndrome (OSA) is one of the most common chronic diseases and is associated with prognostic cardiovascular and metabolic co-morbidities.
- Trial name
- DYNAMIC (NCT04947410)
- Testing
- CPAP or nasal dilators
- Sponsor
- University Hospital, Grenoble
Obstructive Sleep Apnea of Newborn
Nasal and Oronasal Mask in Severe OSA Patients With Nasal Free Airflow of Obstruction
The obstructive sleep apnea (OSA) affects between 10% to 25% of the adults. Continuous positive airway pressure (CPAP) is the first choice of treatment in severe OSA.
- Trial name
- NCT02274194
- Testing
- Nasal CPAP, Oronasal CPAP
- Where
- 2 sites in Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Sleep Apnea, Obstructive
Assessment of Sleep Apnea and Its Causes Before and After Weight Loss Surgery
The central aim of this research project is to determine how the ever-growing problem of obesity in the western world contributes to the pathophysiology of obstructive sleep apnea (OSA).
- Trial name
- NCT01712269
- Testing
- Weight-loss (bariatric) surgery
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Brigham and Women's Hospital
Obstructive Sleep Apnea
Effect of a Very Low Calorie and Low Calorie Diet on Moderate to Severe Obstructive Sleep Apnea in Obese Adults
The purpose of this study is to test the effectiveness of two different weight loss diets on obstructive sleep apnea (OSA) severity.
- Trial name
- NCT02251574
- Testing
- Low Calorie Diet, Very Low Calorie Diet, Standard Care
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
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