Clinical trials: Obstructive Sleep Apnoea Hypopnoea Syndrome
Obstructive Sleep Apnea
The Taiwan OSA Study
We will prospectively recruit 7000 OSA patients referred to the sleep center or China Medical University Hospital between 2020 and 2027.
- Trial name
- TOSA (NCT07302685)
- Where
- Taiwan
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Sleep Disordered Breathing, Obstructive Sleep Apnea
An Investigation to Test a Prototype Full-face Mask in the Home Setting
This investigation is a prospective non-blinded and non-randomized clinical investigation. This investigation is designed to evaluate the performance (leak and comfort) as well as participant's overall acceptance of the Jupiter…
- Trial name
- NCT02938208
- Testing
- Jupiter Full Face Mask
- Where
- 2 sites in New Zealand
- Volunteers
- 14 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea
Evaluatation of Appscent Device Safety and Effectiveness for Relief of Obstructive Sleep Apnea (OSA) Syndrome in Adults.
Obstructive Sleep Apnea (OSA) syndrome is a disorder characterized by repetitive episodes of upper airway obstruction that occur during sleep.
- Trial name
- NCT04609618
- Testing
- Appscent Device
- Where
- Israel
- Volunteers
- 23 people
- Sponsor
- Y.A. Appscent Ltd.
Obstructive Sleep Apnea
Lifestyle Intervention for Obstructive Sleep Apnea in Women
Obesity is a major risk factor for obstructive sleep apnoea (OSA), the most common sleep-disordered breathing related to neurocognitive and metabolic syndromes, type II diabetes, and cardiovascular diseases.
- Trial name
- INTERAPNEA-W (NCT06370806)
- Testing
- Weight loss and lifestyle intervention
- Volunteers
- 180 people
- Sponsor
- Universidad de Granada
Sleep Apnea, Obstructive
Maxillomandibular Advancement Surgery for Treatment of Obstructive Sleep Apnoea Syndrome
This study looks at how jaw surgery called maxillomandibular advancement with counterclockwise rotation affects breathing during sleep in people with moderate to severe obstructive sleep apnea who cannot tolerate standard…
- Trial name
- OSAS (NCT07446634)
- Testing
- Maxillomandibular advancement surgery with counterclockwise rotation
- Where
- Sweden
- Volunteers
- 48 people
- Sponsor
- Jani Talvilahti
Obstructive Sleep Apnea
Hypoglossal Nerve Stimulation in Obstructive Sleep Apnea With Complete Concentric Collapse
This study examines how hypoglossal nerve stimulation affects breathing and sleep apnea in adults whose airway closes from all sides at the soft palate during sleep, a pattern called complete concentric collapse.
- Trial name
- NCT07898618
- Testing
- Inspire Hypoglossal Nerve Stimulation System
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Obstructive Sleep Apnea
The Evaluation of the Toffee Mask for the Treatment of Obstructive Sleep Apnea
This investigation is a prospective, non-randomized, non-blinded study. This investigation is designed to evaluate the performance, comfort and ease of use of the F\&P Toffee mask amongst Obstructive Sleep Apnea (OSA) patients.
- Trial name
- NCT03726346
- Testing
- Toffee Full Face Mask
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnoea, Central Sleep Apnoea
Leg Fluid Shift in Patients With Chronic Heart Failure and Obstructive or Central Sleep Apnea
This study aims to investigate the influence of a potential leg fluid shift (LFS) in patients with chronic heart failure (CHF) and obstructive sleep apnea (OSA) or central sleep apnea (CSA).
- Conditions
- Obstructive Sleep Apnoea, Central Sleep Apnoea, Cheyne Stokes Respiration
- Trial name
- NCT03092388
- Testing
- Multi Frequency Bioimpedance Analysis (mfBIA), Polysomnography/Polygraphy (PSG/PG), Capillary Blood Gas Analysis (CBGA)
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Heart and Diabetes Center North-Rhine Westfalia
Obstructive Sleep Apnea, Tobacco Use
Influence of Tobacco Smoking on the Development of Obstructive Sleep Apnea (OSA)
The aim of this study was to retrospectively evaluate the influence of Tobacco Smoking on the development of Obstructive Sleep Apnea (OSA).
- Trial name
- NCT03574740
- Testing
- Tobacco Smoking
- Volunteers
- 1,298 people
- Sponsor
- Astes
Obstructive Sleep Apnea
Effects of Continuous Positive Airway Pressure (CPAP) in Heart Remodeling by Magnetic Resonance Imaging (MRI)
Obstructive sleep apnea (OSA) is independently associated with important heart remodeling that further contributes to overt heart failure.
- Trial name
- OSA-MRI (NCT00727454)
- Testing
- CPAP, No treatment
- Where
- 2 sites in Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Sleep Apnea, Obstructive
Ambulatory CPAP Titration in Moderate Obstructive Sleep Apnea
The aim of this trial is to compare two different ways of CPAP titration: CAP titration with fixed pressure vs. auto-titrating CPAP.
- Trial name
- ATMOS (NCT04128930)
- Testing
- PAP titration at home
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Obstructive Sleep Apnea
Measuring Effectiveness in Sleep Apnea Surgery
The goal of this research is to improve our understanding of the effectiveness of surgical OSA treatment by evaluating its impact on these health-related and functional outcomes and comparing these effects to the changes in…
- Trial name
- NCT00518128
- Testing
- Surgical OSA treatment, Positive Airway Pressure Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Obstructive Sleep Apnea, Adverse Effects
Comparison of Nasal Positive End Expiratory Pressure Valve to Dental Device as an Alternative Treatment for Obstructive Sleep Apnea
Determine the clinical efficacy in terms of Apnea Hypopnea Index (AHI), excessive daytime sleepiness (EDS), nocturnal oxygenation of a nasal Positive end-expiratory pressure (PEEP) valve "Provent" in obstructive sleep apnea.
- Trial name
- NCT01553383
- Testing
- nasal peep valve "Provent"
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- Chinese University of Hong Kong
Sleep Apnea
Cardiac Dysfunction in Obstructive Sleep Apnea Patients: Prevalence of and Effect of nCPAP
The aim of this study is to clarify the influence of obstructive sleep apnea syndrome on left ventricular function using echocardiographic parameters including the myocardial performance index (Tei-index), and to determine the…
- Trial name
- NCT00503945
- Testing
- Nasal continuous positive airway pressure (nCPAP)
- Where
- Japan
- Volunteers
- 27 people
- Sponsor
- Nagasaki University
Sleep Apnea Syndromes, Sleep Disorder
WatchPAT Device Validation Study Compared to Polysomnography
Validation study of a novel sleep Device compared to a traditional sleep study.
- Conditions
- Sleep Apnea Syndromes, Sleep Disorder, Sleep
- Trial name
- WPAT (NCT03188718)
- Testing
- WatchPAT Intervention
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Obstructive Sleep Apnea, High Flow Nasal Canula
Long-term Effect of High Flow Nasal Canula Therapy on Obstructive Sleep Apnea
Patients meeting the criteria of obstructive sleep apnea were included, and all patients signed informed consent, which met the requirements of the ethics Committee of our unit. All subjects were hospitalized patients.
- Conditions
- Obstructive Sleep Apnea, High Flow Nasal Canula, Continuous Positive Airway Pressure Ventilation
- Trial name
- HFNC (NCT05549310)
- Testing
- CPAP, high-flow nasal canula oxygen therapy
- Where
- China
- Volunteers
- 186 people
- Sponsor
- Qilu Hospital of Shandong University
Pediatric Obstructive Sleep Apnea, Down Syndrome (DS)
Pediatric Down Syndrome Post-Approval Study
The purpose of this Post Approval research study is to assess ongoing safety and effectiveness of the Inspire therapy in adolescents and young adults (age 13-18) with Down syndrome and severe sleep apnea.
- Trial name
- NCT06851338
- Testing
- Hypoglossal Nerve Stimulation
- Where
- 6 sites in United States
- Volunteers
- 60 people
- Sponsor
- Inspire Medical Systems, Inc.
Obstructive Sleep Apnea
The Evaluation of a Nasal Pillows Mask for the Treatment of Obstructive Sleep Apnea (OSA) in NZ
This investigation is designed to evaluate the performance (leak and comfort) as well as the participant's overall acceptance of the nasal pillows mask amongst Obstructive Sleep Apnea (OSA) participants.
- Trial name
- NCT02741635
- Testing
- New Nasal Pillows Mask
- Where
- New Zealand
- Volunteers
- 15 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea
Investigative Headgear With CPAP Mask
This investigation is designed to evaluate the at-home usability, performance, user acceptance and reliability of the Headgear with a CPAP Mask for a duration of 2-4 weeks.
- Trial name
- NCT02323035
- Testing
- Headgear
- Where
- New Zealand
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea
Validation of Sleep Healthcare System
The present project aims to that examine the interplay between sleep duration circadian phase, and metabolic regulation. The impact of CPAP therapy on metabolic regulation is assessed with a RCT.
- Trial name
- NCT04252482
- Testing
- CPAP
- Where
- Taiwan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.