Clinical trials: Obstructive Tonsillar Hypertrophy
Tonsillar Hypertrophy, Sleep Apnea, Obstructive
Intracapsular Tonsillectomy in the Treatment of Obstructive Sleep Apnea in Adults
Treating sleep apnea in adults caused by tonsillar hypertrophy with intracapsular tonsillectomy by coblation
- Trial name
- NCT04314492
- Testing
- Tonsillectomy
- Where
- 2 sites in Finland
- Volunteers
- 25 people
- Sponsor
- Turku University Hospital
Obstructive Sleep Apnea of Child
Single Cell Sequencing of Tonsillar Tissue in Children With OSA
Obstructive sleep apnoea (OSA) in children is a prevalent sleep disorder, and is characterised by repetitive complete or partial upper airway obstruction during sleep.
- Trial name
- NCT05115968
- Testing
- Tonsillectomy
- Where
- Hong Kong
- Volunteers
- 16 people
- Sponsor
- Chinese University of Hong Kong
Obstructive Sleep Disorder, Obstructive Sleep Apnea
Topical Microporous Polysaccharide Hemospheres Versus Electrocautery for Control of Pediatric Post-Tonsillectomy Bleeding
The ultimate goal of this work is to establish a method for control bleeding after tonsillectomy in awake children. Treatment of post-tonsillectomy bleeding in children typically requires general anesthesia with currently used…
- Conditions
- Obstructive Sleep Disorder, Obstructive Sleep Apnea, Tonsillar Hypertrophy
- Trial name
- NCT00945412
- Testing
- Micropolysaccharide Hemospheres (Arista), Electrocautery (Monopolar suction cautery)
- Where
- United States
- Sponsor
- Massachusetts Eye and Ear Infirmary
Obstructive Sleep Apnea, Tonsillar Hypertrophy
Tonsillectomy vs. Tonsillotomy in Adults With Obstructive Sleep Apnea
The primary purpose of this randomized controlled trial s to investigate whether surgical reduction of palatine tonsils (tonsillotomy) is a superior treatment compared to complete surgical removal of palatine tonsils…
- Trial name
- NCT06376383
- Testing
- Tonsillectomy, Tonsillotomy
- Volunteers
- 464 people
- Sponsor
- University of Aarhus
Obstructive Sleep Apnea, Tonsillar Hypertrophy
Long-term Results of Tonsillectomy in the Treatment of Obstructive Sleep Apnea in Adults
Long-term results of tonsillectomy in the treatment of obstructive sleep apnea in adults
- Conditions
- Obstructive Sleep Apnea, Tonsillar Hypertrophy, Sleep Apnea Syndromes
- Trial name
- NCT05049369
- Testing
- Polysomnography
- Where
- Finland
- Volunteers
- 17 people
- Sponsor
- Turku University Hospital
Obstructive Sleep Apnea, Enlargement of Tonsil or Adenoid
Caffeine in Children With Obstructive Sleep Apnea, Dose Response Study
The aim of this study is to evaluate whether a smaller dose of caffeine sodium benzoate 10 mg/kg IV is as effective as 20 mg/kg IV in decreasing the number of children who develop post extubation adverse upper airway respiratory…
- Trial name
- NCT01349205
- Testing
- Caffeine and sodium Benzoate 10 mg/kg IV, Caffeine and Sodium Benzoate 20 mg/kg IV, 0.9 NS Saline
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Obstructive Tonsillar Hypertrophy, Tonsillitis
Randomized Controlled Study of Plasmaknife Tonsillectomy Versus Monopolar Tonsillectomy
Study objective is to provide prospective randomized controlled data on pediatric pain levels found in PlasmaKnife tonsillectomy and monopolar tonsillectomy.
- Trial name
- jPK (NCT00466544)
- Testing
- Plasmaknife, Monopolar
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Children's Hospital of Michigan
Obstructive Tonsillar Hypertrophy
Development of an Assessment Method for Obstructive Tonsillar Hypertrophy in Children by Ultrasonography
Chronic tonsillar hypertrophy is one of the most common causes of upper airway obstruction in children. Currently, several clinical staging systems are used to evaluate airway obstruction due to tonsillar hypertrophy.
- Trial name
- NCT04380272
- Testing
- The ROC analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Pamukkale University
Pediatric Obstructive Sleep Apnea
Oral Corticosteroids' Role in Pediatric Obstructive Sleep Apnea
This prospective interventional clinical trial (non-randomized) aims to evaluate oral corticosteroids' role as an alternative to surgery (gold-standard) in the treatment of obstructive sleep apnea in children.
- Trial name
- NCT06917768
- Testing
- Adenotonsillectomy, Prednisolone
- Where
- Lebanon
- Volunteers
- 87 people
- Sponsor
- Hotel Dieu de France Hospital
Sleep Apnea, Obstructives, Tonsil Hypertrophy
Randomized Clinical Trial for Tonsil Surgery in Adults With Obstructive Sleep Apnea and Enlarged Tonsils
The aim is to investigate whether the tissue-preserving tonsil surgery technique is as effective as complete tonsil removal in the treatment of obstructive sleep apnea.
- Trial name
- TONOS (NCT07580170)
- Testing
- Tonsillectomy, Tonsillotomy
- Where
- 4 sites in Finland
- Volunteers
- 132 people
- Sponsor
- Turku University Hospital
Apnea, Obstructive, Tonsillitis
Evaluation of the Functional Impact of Adenotonsilectomy
Spirometric assessment of respiratory function before and after adenotonsillectomy surgery
- Conditions
- Apnea, Obstructive, Tonsillitis, Tonsillar Hypertrophy, Respiratory Function Impaired
- Trial name
- NCT05532228
- Testing
- Adenotonsillectomy
- Where
- Portugal
- Volunteers
- 78 people
- Sponsor
- Instituto de Ciências Biomédicas Abel Salazar
Enlargement of Tonsil or Adenoid
Bioclinical Profile of Adenotonsillar Hypertrophy in the Pediatric Population
Adenotonsillar hypertrophy is the principal cause of obstructive sleep apnea of childhood, yet little is known with regard to its pathophysiologic and molecular mechanisms.
- Trial name
- NCT03541434
- Testing
- Complete Blood Count, Tympanometry, Tonsillectomy and/or adenoidectomy
- Where
- 2 sites in Greece
- Volunteers
- 134 people
- Sponsor
- University of Patras
Sleep-Disordered Breathing, Sleep Apnea Syndromes in Children
Lateral Pharyngoplasty Outcomes in Children Undergoing Tonsillectomy
The goal of this treatment study is to determine if doing lateral pharyngoplasty with tonsillectomy is better for children than doing tonsillectomy alone.
- Conditions
- Sleep-Disordered Breathing, Sleep Apnea Syndromes in Children, Sleep Apnea, Obstructive, Tonsillitis
- Trial name
- NCT05575401
- Testing
- Lateral pharyngoplasty, Tonsillectomy
- Where
- 4 sites in United States
- Volunteers
- 160 people
- Sponsor
- Loma Linda University
Sleep Disorder; Breathing-Related, Snoring
Intranasal Steroid as Medical Therapy For Sleep-Disordered Breathing in Children
MIST+ is studying a nasal spray to see if it will reduce the need for surgery for snoring. Children aged 3-12 are invited to take part.
- Conditions
- Sleep Disorder; Breathing-Related, Snoring, Obstructive Sleep Apnea of Child, Sleep Disorders in Children
- Trial name
- MIST+ (NCT05382494)
- Testing
- Mometasone Furoate 50mcg Nasal Spray, Sodium Chloride 0.9 % Nasal Spray
- Where
- 2 sites in Australia
- Volunteers
- 130 people
- Sponsor
- Murdoch Childrens Research Institute
Pediatric Sleep Apnea, Obstructive Sleep Apnea
Photobiomodulation for Pediatric Hypertrophic Tonsils
Pediatric obstructive sleep apnea is a medical condition where a child has great difficulty with breathing, or stops breathing all together, while asleep.
- Conditions
- Pediatric Sleep Apnea, Obstructive Sleep Apnea, Tonsils Hypertrophy
- Trial name
- NCT05459935
- Testing
- PBM Tonsil Arm
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Children, Postoperative Pain
Acupuncture for Tonsillectomy Pain
Pain after tonsillectomy can be severe and last ten days. Various new surgical instruments have been developed over the years in an attempt to reduce postoperative pain with mixed results and increased costs; no single…
- Conditions
- Children, Postoperative Pain, Tonsillar Hypertrophy, Obstructive Sleep Apnea
- Trial name
- NCT01389349
- Testing
- Acupuncture
- Where
- 2 sites in United States
- Volunteers
- 130 people
- Sponsor
- Children's ENT of San Diego, Inc.
Obstructive Sleep Apnea
Tonsillectomy in Adults With Tonsillar Hypertrophy and Obstructive Sleep Apnea
The purpose of the study is to determine if tonsillectomy eliminates symptoms of obstructive sleep apnea in patients with obstructive sleep apnea and marked tonsillar hypertrophy with normal soft palate and uvula length.
- Trial name
- NCT02204696
- Testing
- Tonsillectomy
- Where
- United States
- Sponsor
- University of Southern California