Clinical trials: Obstructive Ventilation Disorder
COPD, Severe Systemic Illness-induced Respiratory Muscle Wasting
Effects of Inspiratory Muscle Training on Dyspnea Perception During Exercise in Patients With COPD
Patients with chronic obstructive pulmonary disease are often limited in their exercise capacity by intolerable shortness of breath (dyspnea).
- Trial name
- IMTCOCOPD (NCT01900873)
- Testing
- Inspiratory Muscle Strength Training, Inspiratory Muscle Endurance Training
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- KU Leuven
Chronic Rhinosinusitis With Nasal Polyps, Obstructive Sleep Apnea
Polysomnographic Findings in Nasal Polyposis
Nasal polyposis (NP) is a chronic inflammatory disease of the nasal and sinus mucosa leading to protrusion of edematous polyps in the nasal cavity. Prevalence of NP among the chronic rhinosinusitis patients is 25-30 %.
- Trial name
- POLYSOMNO (NCT03725956)
- Testing
- Endoscopic sinus surgery
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Lille
Obstructive Sleep Apnoea (OSA)
Assessment of the Performance of a New Reduced Noise Mask Vent
As continuous positive airway pressure is the treatment of choice for OSA, a mask is vital in ensuring the effectiveness of therapy delivery. The study will evaluate the performance and usability of the new mask vent.
- Trial name
- NCT01575210
- Testing
- CPAP mask
- Where
- Australia
- Volunteers
- 31 people
- Sponsor
- ResMed
Chronic Obstructive Pulmonary Disease, Hypercapnic Respiratory Failure
Withdrawal of Non-invasive Ventilation in Chronic Obstructive Pulmonary Disease (COPD) Patients With Acute Hypercapnic Respiratory Failure
The investigators design a pilot randomised, single-centred, controlled trial to compare different withdrawal methods of Non-invasive ventilation.
- Trial name
- NCT01523470
- Testing
- BIPAP Synchrony
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- United Christian Hospital
Obstructive Sleep Apnea
FAST as a Treatment for Obstructive Sleep Apnea
The objective of this study is to assess the feasibility and safety of tongue suspension using the Siesta Medical Encore Tongue Suspension System for the treatment of obstructive sleep apnea (OSA).
- Trial name
- FAST (NCT01611779)
- Testing
- Encore Tongue Suspension System
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Siesta Medical, Inc.
Sleep Apnea, Obstructive, Chronic Obstructive Pulmonary Disease
SNORE (Smartphone Analyses of Nocturnal Obstruction by Respiratory Evaluation) SOUNDS
This is a prospective multipart clinical performance study to compare the ability of the SnoreSounds algorithm with polysomnography (PSG) and a type III Home Sleep Testing (HST) device to identify patients with obstructive sleep…
- Trial name
- SNORESOUNDS (NCT03288376)
- Where
- 3 sites in United States
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Incyphae, Inc.
Obstructive Sleep Apnea
Screening for Obstructive Sleep Apnea Among Members of an Internet Weight Loss Community
The current study was a pilot, double blind, randomized controlled trial to (1) evaluate the feasibility of an online obstructive sleep apnea (OSA) screening intervention, (2) estimate effect size for planning of future studies…
- Trial name
- NCT00808574
- Testing
- Obstructive sleep apnea screening intervention
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Acute Respiratory Failure
Continuous Positive Airway Pressure and Oxygen Concentration on Measurement of Rapid Shallow Breathing Index
To compare the rapid shallow breathing index (RSBI) values, the incidence of adverse reactions, and the predictive accuracy measured under 5 different ventilator strategies in the same patient group.
- Trial name
- NCT00632320
- Where
- Taiwan
- Volunteers
- 98 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
COPD, Chronic Hypercapnic Respiratory Failure
Short Term Physiological Effects of Nasal High Flow Oxygen on Respiratory Mechanics
Nasal High Oxygen Flow (HOF) has been demonstrated to reduce the re-intubation rate in hypoxic patients and ameliorate breathing pattern in hypercapnic patients.
- Trial name
- NCT02363920
- Testing
- HOF, noninvasive mechanical ventilation (NIV)
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Obstructive Sleep Apnea
CPAP In-home Assessment USA
The study is to evaluate the product reliability, therapy effectiveness and user feedback of a Continuous Positive Airway Pressure (CPAP) device in-home for up to 6 months.
- Trial name
- NCT02809859
- Testing
- Fisher & Paykel Healthcare CPAP Device
- Where
- 4 sites in United States
- Volunteers
- 139 people
- Sponsor
- Fisher and Paykel Healthcare
Respiratory Disease, Bronchiolitis, Viral
SWISH Trial (Strategies for Weaning Infants on Supportive High Flow)
Bronchiolitis is a common type of chest infection that tends to affect babies and young children under a year old. In older children and adults, the same viruses that cause bronchiolitis lead to the 'common cold'.
- Conditions
- Respiratory Disease, Bronchiolitis, Viral, Infant Morbidity
- Trial name
- SWISH (NCT04287959)
- Testing
- High flow nasal cannula support
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cardiff and Vale University Health Board
Chronic Obstructive Pulmonary Disease
SCOPE-Study: Salzburg Chronic Obstructive Pulmonary Disease- Exercise and Oxygen Study
Chronic obstructive pulmonary disease (COPD) is number four of the leading causes of death in the USA and Europe. Moreover, among the top five causes of death, this disease is the only one with increasing mortality rates.
- Trial name
- SCOPE (NCT01150383)
- Testing
- Physical exercise training with supplemental oxygen, Physical exercise training with "room air supplementation"
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Paracelsus Medical University
Apnea, Snoring
Polidocanol Sclerotherapy of Pharynges for Obstructive Sleep Apnea (OSA) and Snoring Subjects(SS)
The aim of this prospective study is to evaluate the results of polidocanol sclerotherapy of pharynx for OSAS \& SS,to reduce pharyngeal compliance.
- Trial name
- NCT00399451
- Testing
- Polidocanol Sclerotherapy
- Volunteers
- 30 people
- Sponsor
- Liaoyang Central Hospital
Obstructive Sleep Apnea (OSA)
C-LIFT Efficacy in Patients With Obstructive Sleep Apnea
The goal of this clinical trial is to evaluate the efficacy of the C-Lift Device as a non-invasive treatment for Sleep Disordered Breathing (SDB) within the population of adults diagnosed with moderate to severe Obstructive Sleep…
- Trial name
- EOSA (NCT07807124)
- Testing
- C-Lift
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Ata Murat Kaynar
Obstructive Sleep Apnea (OSA)
The Effectiveness of Perioperative CPAP to Reduce Obstructive Sleep Apnea Related Adverse Events
Objective of the study: To determine whether Perioperative Auto-CPAP treatment prevent postoperative worsening of OSA and improve nocturnal oxygen saturation in surgical patients with moderate and severe OSA.
- Trial name
- NCT01249924
- Testing
- auto-titrated CPAP, Control
- Where
- 2 sites in Canada
- Volunteers
- 120 people
- Sponsor
- University Health Network, Toronto
Obstructive Sleep Apnea
Exploration of Current and New Technologies for Accuracy of Diagnosing OSA
Resmed is the manufacturer of medical devices which screen, diagnose, treat and monitor people with sleeping and respiratory disorders, such as obstructive sleep apnea (OSA).
- Trial name
- NCT07485582
- Testing
- Device A, Device B, Device C
- Where
- 5 sites in Australia
- Volunteers
- 90 people
- Sponsor
- ResMed
Obstructive Sleep Apnea Syndrome
Efficacy of autoPPC for the Treatment of Obstructive Sleep Apnea Syndrome (OSAS)
Obstructive Sleep Apnea Syndrome (OSAS) is a common condition that leads to daytime sleepiness and loss of vigilance and, in addition, increased risk of cardiovascular events.
- Trial name
- NCT00875680
- Testing
- autoPPC
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche
Multiple Sclerosis
CPAP to Treat Cognitive Dysfunction in MS
The objectives of this study are to determine the effects of obstructive sleep apnea (OSA) on cognitive function in patients with multiple sclerosis (MS); and to evaluate whether OSA treatment with positive airway pressure…
- Trial name
- NCT02544373
- Testing
- PAP therapy
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- University of Michigan
Obstructive Sleep Apnea
Validation of Sleep Apnea Screening Device
Obstructive sleep apnea (OSA) is the most common type of sleep apnea. OSA affects an estimated 18-40 million adults and 0.7-3% of all children in the US.
- Trial name
- NCT02814227
- Testing
- Zansors® sleep screening device
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Michigan
Sleep Apnea, Obstructive
The Effect of Orofacial Myofunctional Therapy With Autofeedback on Obstructive Sleep Apnea
The overall aim of this study is to estimate the effect of orofacial myofunctional therapy (OMT) plus auto-monitoring compared to auto-monitoring alone.
- Trial name
- OMTAOSA (NCT06079073)
- Testing
- Orofacial myofunctional therapy with autofeedback
- Where
- 2 sites in Estonia, Norway
- Volunteers
- 106 people
- Sponsor
- University Hospital, Akershus
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