Clinical trials: Occlusion, Cerebrovascular
Moyamoya Disease, Gut Microbiota
Gut Microbiota in Patients With Moyamoya Disease
This study is to find out the association between gut microbiota and moyamoya disease.
- Trial name
- NCT04890782
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Ischemic Stroke, Atheroscleroses, Cerebral
Morphology of Advanced Symptomatic Cerebral Plaques With High Embolic Potential
The study is to attain early recognition of the unstable plaques which have an imminent embolic risk in patients with intracranial atherosclerotic disease (IAD).
- Trial name
- NCT03291652
- Testing
- DSA/3DRA
- Where
- Hong Kong
- Volunteers
- 140 people
- Sponsor
- Chinese University of Hong Kong
Subarachnoid Hemorrhage, Headache
Efficacy of Percutaneous SPG Block in Aneurysmal SAH
Researchers are trying to develop alternative means to help patients with headache pain secondary to aneurysmal subarachnoid hemorrhage (bleeding about the brain).
- Trial name
- NCT04331938
- Testing
- Regional anesthetic SPG block-bilateral
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic
Acute Ischemic Stroke
Safety and Efficacy Evaluation of the iNstroke 4F Thromboaspiration Catheter in Patients With Acute Ischaemic Stroke Due to Primary Distal Medium Vessel Occlusions (DMVO)
Prospective, Single-arm, Multi-centre Study to Evaluate the Efficacy and Safety of the iNstroke 4F Thromboaspiration Catheter in Patients with Acute Ischaemic Stroke due to Primary Distal Medium Vessel Occlusions.
- Trial name
- 4-NiVO (NCT07357285)
- Testing
- Thromboaspiration catheter
- Where
- 11 sites in Germany, Hungary and 1 more
- Volunteers
- 57 people
- Sponsor
- iVascular S.L.U.
Ischemic Stroke, Acute Stroke
Mechanical Thrombectomy for Acute Large Vessel Occlusion Stroke With Mild Symptoms
Mechanical thrombectomy(MT) has been recommended in patients with acute large vessel occlusion stroke(LVO) , especially for those with National Institutes of Health Stroke Scale (NIHSS) score ≥6.
- Trial name
- NCT04526756
- Testing
- Mechanical Thrombectomy
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Shanghai East Hospital
Peripheral Vascular Disease, Peripheral Artery Disease
Platelet Activity in Vascular Surgery for Thrombosis and Bleeding
The proposed PIVOTAL study will examine a panel of platelet/coagulation activity markers during the perioperative period. The goal is to develop a clinically useful assessment of platelet/coagulation activity for risk…
- Conditions
- Peripheral Vascular Disease, Peripheral Artery Disease, Carotid Stenosis, Aortic Aneurysm, Abdominal
- Trial name
- PIVOTAL (NCT01897103)
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- NYU Langone Health
Ischemic Stroke, Stroke
Gravity Stent-Retriever System For Reperfusion Of Large Vessel Occlusion Stroke Trial
The study aims to evaluate the safety and efficacy of the Supernova stent retriever device, developed by Gravity Medical Technology, for treating acute ischemic stroke.
- Conditions
- Ischemic Stroke, Stroke, Cerebrovascular Disorders, Brain Diseases
- Trial name
- GRASSROOT (NCT06249776)
- Testing
- Supernova revascularization device
- Where
- 11 sites in India, Iran and 1 more
- Volunteers
- 55 people
- Sponsor
- Gravity Medical Technology, INC
Intracranial Atherosclerosis, Cognitive Impairment
Cognitive Decline and Underlying Mechanisms in Symptomatic Intracranial Artery Stenosis Patients: A Cohort Study
The purpose of this study is to explore the mechanism of cognitive impairment in patients with symptomatic intracranial atherosclerotic stenosis (ICAS), and further plans to explore the impact of different treatment options on…
- Conditions
- Intracranial Atherosclerosis, Cognitive Impairment, Cerebrovascular Event
- Trial name
- NCT06336174
- Testing
- Aspirin Tablet, Clopidogrel Bisulfate Tablets and Atorvastatin, Endovascular therapy,Aspirin Tablet, Clopidogrel Bisulfate Tablets and Atorvastatin
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Anhui Medical University
Carotid Artery Diseases, Thrombectomy
Thrombectomy In TANdem Occlusion
Tandem occlusion is defined by an acute ischemic stroke (AIS) with concomitant steno-occlusive disease of the extra cranial carotid artery and concerned about 10% of AIS patients.
- Conditions
- Carotid Artery Diseases, Thrombectomy, Tandem Occlusion, Stroke
- Trial name
- TITAN (NCT03978988)
- Testing
- Carotid Stenting, Procedural Aspirin, Dual dual antiplatelet therapy after 24-hours imaging follow-up
- Where
- France
- Volunteers
- 432 people
- Sponsor
- Central Hospital, Nancy, France
Acute Coronary Syndrome, Coronary Artery Disease
Salts of Clopidogrel: Investigation to ENsure Clinical Equivalence
Clopidogrel besylate (CB) is not differentiated relative to the orignal clopidogrel hydrogen sulfate (CHS) in the pharmacokinetics and in antiplatelet potency in healthy volunteers.
- Conditions
- Acute Coronary Syndrome, Coronary Artery Disease, Ischemic Stroke, Peripheral Artery Disease
- Trial name
- SCIENCE (NCT02126982)
- Where
- Greece
- Volunteers
- 1,500 people
- Sponsor
- University of Ioannina
Delirium, Ischemic Stroke
CTSN Embolic Protection Trial
This is a prospective, multi-center, randomized effectiveness trial of the CardioGard Embolic Protection Cannula in high-risk valve surgery patients.
- Conditions
- Delirium, Ischemic Stroke, Acute Kidney Injury, Heart Valve Disease
- Trial name
- EMPRO (NCT06027788)
- Testing
- CardioGard Embolic Protection Cannula, Standard Aortic Cannula
- Where
- 24 sites in United States, Canada
- Volunteers
- 842 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Symptomatic Non-acute Intracranial Artery Occlusion, Ischemic Stroke
Randomized Clinical Trial of Endovascular Recanalization for Symptomatic Non-Acute Intracranial Artery Occlusion（REPAIR）
A multicenter, randomized, open-label, endpoint-blinded trial to compare the effects of endovascular recanalization plus aggressive medical management with aggressive medical management alone on stroke recurrence and mortality in…
- Trial name
- NCT07495969
- Testing
- Endovascular Recanalization Strategy, Aggressive Medical Management
- Where
- China
- Volunteers
- 286 people
- Sponsor
- Feng Gao
Carotid Artery Stenosis
Evaluation of the Ton-bridge Carotid Stent for Carotid Artery Stenosis
The purpose of this trial is to evaluate effectiveness and safety of the Ton-bridge carotid stent for the treatment of carotid artery stenosis.
- Trial name
- NCT06365697
- Testing
- Ton-bridge carotid stent, WALLSTENT carotid stent
- Where
- 7 sites in China
- Volunteers
- 188 people
- Sponsor
- Ton-Bridge Medical Tech. Co., Ltd
Ischemic Stroke, Atherosclerosis of Artery
Efficacy of Probucol Combined with Statins Treatment for Ischemic Stroke
The goal of this clinical trial is to evaluate whether the combination of Probucol with statin therapy can reduce the risk of vascular events and improve atherosclerosis outcomes in adults with ischemic stroke and confirmed…
- Conditions
- Ischemic Stroke, Atherosclerosis of Artery, Lipid Disorder, Statin
- Trial name
- EPCIS (NCT06604117)
- Testing
- Statin, Probucol
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke, Acute, Stroke, Ischemic
Endovascular Treatment With Versus Without Intravenous rhTNK-tPA in Stroke
The purpose of this trial is to investigate whether intravenous rhTNK-tPA prior to endovascular treatment can improve 90-day functional outcome of stroke patients with large vessel occlusion who are thrombolysis-eligible within…
- Trial name
- BRIDGE-TNK (NCT04733742)
- Testing
- rhTNK-tPA, Endovascular treatment
- Where
- 6 sites in China
- Volunteers
- 550 people
- Sponsor
- Xinqiao Hospital of Chongqing
Dementia, Dementia, Vascular
Feasibility of the SmartPrompt for Improving Everyday Function in Dementia
Difficulty completing everyday tasks is a primary reason for the high cost of care, loss of caregiver paid hours, and general caregiver burden associated with dementia.
- Conditions
- Dementia, Dementia, Vascular, Dementia Alzheimers, Dementia, Mixed
- Trial name
- SmartPrompt (NCT04313582)
- Testing
- SmartPrompt smartphone application
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Temple University
Cognitive Function, Stenosis
Clinical Registration Study of Patients With Intracranial / Carotid Stenosis
Through prospective registration and follow-up, this study will collect data of patients with intracranial/carotid stenosis, including clinical information, neuropsychological scales, multimodal magnetic resonance images.
- Trial name
- NCT05322824
- Testing
- standard medical treatment, Interventional stenting
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke, Acute Ischemic, Albumin
Intra-arterial Albumin Infusion After Endovascular Therapy for Stroke Patients
The purpose of this study is to investigate the safety and feasibility of intra-arterial albumin infusion for patients with acute ischemic stroke after successful thrombectomy and to further explore the optimal dose of albumin…
- Conditions
- Stroke, Acute Ischemic, Albumin, Endovascular Procedures, Large Vessel Occlusion
- Trial name
- NCT05953623
- Testing
- Albumin
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Tianjin Huanhu Hospital
Acute Ischemic Stroke
Safety and Efficacy of Remote Ischemic Conditioning in Patients With Severe Stenosis or Occlusion of Anterior Intracranial Circulation Vessels
The primary purpose of this study is to examine whether remote ischemic treatment can better the 90 - day neurological outcomes in acute ischemic stroke patients having severe stenosis or occlusion of anterior intracranial…
- Trial name
- RICASO (NCT06823128)
- Testing
- RIC, Guideline-based therapy
- Where
- China
- Volunteers
- 458 people
- Sponsor
- The First Affiliated Hospital of University of Science and Technology of China
Stroke, Ischemic
EEG Patterns in Patients With Acute Ischemic Stroke Resulted From Large Vessels Occlusion in the Anterior Circulation
Clinical deterioration is observing in up to forty percent of patients with acute ischemic stroke (AIS) due to large vessels occlusion.
- Trial name
- NCT04412434
- Testing
- Electroencephalography (EEG)
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- rambam62
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