Clinical trials: Occlusion, Cerebrovascular
Coronary Artery Disease, Cerebral Stroke
Mechanistic Study of Bleeding Risk in Coronary Patients With Cerebrovascular Disease
Background: About 5% of patients with acute coronary syndrome (ACS) have had previously ischemic stroke (IS) or transitory ischemic attack (TIA).
- Conditions
- Coronary Artery Disease, Cerebral Stroke, TIA (Transient Ischemic Attack)
- Trial name
- NCT02316119
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- University of Sao Paulo General Hospital
Stroke, Thrombectomy
Results of the Use of Two Stentrievers Simultaneosly Compared With One as a Primary Treatment in Acute Ischemic Stroke
Several studies have demonstrated that simultaneous treatment with two stentrievers (STs) as rescue treatment is very effective, with high recanalization rates even in this group of patients where other revascularization…
- Conditions
- Stroke, Thrombectomy, Arterial Occlusive Diseases
- Trial name
- DIVERSO (NCT05930145)
- Testing
- Double stentriever, Single stentriever
- Where
- 4 sites in Germany, Spain
- Volunteers
- 200 people
- Sponsor
- Fundación EPIC
Carotid Stenosis, Carotid Artery Diseases
Cerebral Oximetry During Awake Carotid Endarterectomy
Surgery to remove plaque from the carotid artery in the neck requires the artery to be clamped for a period of time. In some patients this reduces blood flow to the brain enough to cause temporary symptoms, and a temporary…
- Conditions
- Carotid Stenosis, Carotid Artery Diseases, Brain Ischemia, Carotid Endarterectomy
- Trial name
- COACE (NCT07816081)
- Testing
- Masked continuous cerebral oximetry, Standardised awake neurological test, Serial cognitive assessment
- Where
- Vietnam
- Volunteers
- 150 people
- Sponsor
- Nguyen Toan Thang
Carotid Stenosis, Optical Coherence Tomography (OCT)
Endovascular Treatment of Cerebrovascular Diseases Guided by Optical Coherence Tomography (OCT) Technology（CVD-OCT）
OCT techniques have been used in the assessment of both intracranial and extracranial lesions.(1) Preprocedural evaluation: The morphologic characteristics of carotid atherosclerotic plaques can be evaluated by OCT before surgery…
- Conditions
- Carotid Stenosis, Optical Coherence Tomography (OCT), Endovascular Treatment
- Trial name
- （CVD-OCT) (NCT06986330)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Microcirculation, Coronary Artery Disease
The Cerebral Microcirculation Diseases and Coronary Microcirculation Disease Study
Ischaemic heart disease (IHD) and degenerative brain disease are two major sources of death and disability affecting all countries.
- Conditions
- Microcirculation, Coronary Artery Disease, Cerebrovascular Circulation
- Trial name
- CCMD (NCT06368635)
- Testing
- Coronary angiography
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Weijing Wang
Carotid Stenosis
A Prospective, Non-Randomized, Evaluation of Low-Risk Patients Undergoing Carotid Stenting With ANgiomax (Bivalirudin)
Prospective, non-randomized, single-center cohort study treating internal carotid artery stenosis using the Xact Carotid Artery Stent and emboshield distal protection system in conjunction with bivalirudin as the procedural…
- Trial name
- NCT01273350
- Testing
- Carotid PTA and stenting
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- SPSI d.b.a Capital Cardiovascular Associates
Atherosclerosis
Progression of Early Subclinical Atherosclerosis
The overall objective of this study is to characterize the prevalence and progression rate of subclinical atherosclerotic lesions and to study their association to the imaging characteristics of atheroma plaques and to the…
- Trial name
- PESA (NCT01410318)
- Where
- Spain
- Volunteers
- 4,184 people, healthy volunteers welcome
- Sponsor
- Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III
Internal Carotid Artery Stenosis
The Observation About the Effects of Internal Carotid Artery Stenosis on Fundus Vessels and the Changes of Fundus Vessels After Interventional Therapy
The investigators plan to collect 30 participants with internal carotid artery stenosis to observed the relationship between the degree of internal carotid artery stenosis and fundus vessels （and blood flow）density before…
- Trial name
- NCT05260229
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Carotid Artery Diseases, Peripheral Artery Disease
Assessment of Carotid Artery Stenosis and Lower Limb Peripheral Ischemia Prior to CABG
From our experience among Egyptian population in our institution, there is an increased prevalence of hidden subclinical peripheral artery disease along with carotid artery affection.
- Trial name
- NCT03516929
- Testing
- carotid duplex, both LL arterial duplex
- Where
- Egypt
- Volunteers
- 360 people
- Sponsor
- Mr Ihab Ali
Carotid Artery Stenosis
Predictive Value for Stroke
Patients with a moderate to severe carotid atherosclerotic plaque are at risk for stroke and this risk increases with increasing degree of stenosis.
- Trial name
- NCT00451529
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Dutch Heart Foundation
Carotid Artery Plaque
Carotid Artery Plaque Vulnerability Assessment Using Ultrafast Ultrasound Techniques
Objective: To explore the association between spatio-temporal blood flow velocities (peak systole and end-diastole at prior-stenosis, at maximum stenosis, and post-stenosis) and carotid plaque vulnerability defined by histology…
- Trial name
- CAP-VALUE (NCT05218421)
- Testing
- Carotid ultrasound, Biospecimen collection and examination, Blood sample collection
- Where
- 2 sites in Netherlands
- Volunteers
- 70 people
- Sponsor
- Radboud University Medical Center
Atrial Fibrillation, Stroke
Evaluation of WATCHMAN Left Atrial Appendage Occlusion Device in Patients With Atrial Fibrillation Versus Rivaroxaban
This is a prospective, multi-center, randomized, pilot study comparing the WATCHMAN left atrial appendage occlusion device with Rivaroxaban therapy in patients with non-valvular atrial fibrillation.
- Trial name
- NCT02549963
- Testing
- WATCHMAN Left Atrial Appendage Occlusion Device, Rivaroxaban
- Where
- 9 sites in China
- Volunteers
- 200 people
- Sponsor
- Shulin Wu
Coronary Artery Disease
Eliminate Coronary Artery Disease
The purpose of this study is to determine whether pharmacologic lowering of low density lipoprotein cholesterol (LDL), initiated in healthy young to middle aged adults can eliminate or markedly reduce the composite endpoint of…
- Trial name
- ECAD (NCT02245087)
- Testing
- Atorvastatin
- Where
- 3 sites in Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Ischemic Stroke, Atheroscleroses, Cerebral
Morphology of Advanced Symptomatic Cerebral Plaques With High Embolic Potential
The study is to attain early recognition of the unstable plaques which have an imminent embolic risk in patients with intracranial atherosclerotic disease (IAD).
- Trial name
- NCT03291652
- Testing
- DSA/3DRA
- Where
- Hong Kong
- Volunteers
- 140 people
- Sponsor
- Chinese University of Hong Kong
Intracranial Aneurysm, Postoperative Pain
Effect of Bilateral Greater Occipital Nerve Block on Headache After Intracranial Aneurysm Coiling
Postoperative headache is a common complication following endovascular coil embolization of intracranial aneurysms and may increase analgesic requirements, impair patient comfort, and contribute to hemodynamic instability.
- Trial name
- NCT07910864
- Testing
- Ultrasound-Guided Bilateral Greater Occipital Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Konya City Hospital
Acute Ischemic Stroke
Adjunctive Use of Intra-Arterial TNK and Albumin Following Thrombectomy
The purpose of this study is to investigate the feasibility and efficacy of intra-arterial TNK and albumin for patients with acute ischemic stroke after successful thrombectomy and whether there is a synergistic effect between…
- Trial name
- NCT06113848
- Testing
- Intra-Arterial TNK and Albumin, Intra-Arterial TNK, Intra-Arterial Albumin
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Tianjin Huanhu Hospital
Acute Ischemic Stroke, Atrial Fibrillation
Adding Antiplatelet During Edoxaban Treatment in Stroke Patients With Non-valvular Atrial Fibrillation (ADD-ON)
This study aims to compare the effectiveness and safety regarding treatment with standard anticoagulant only or adding antiplatelet to anticoagulant in patients with non-valvular atrial fibrillation and significant…
- Conditions
- Acute Ischemic Stroke, Atrial Fibrillation, Extracranial Atherosclerosis, Intracranial Atherosclerosis
- Trial name
- (ADD-ON) (NCT04010955)
- Testing
- Edoxaban Monotherapy
- Where
- South Korea
- Volunteers
- 1,200 people
- Sponsor
- Asan Medical Center
Atherosclerosis, Aortic Aneurysm
Physical,Histological,and Genetic Analyses of Lipid-rich Atherosclerotic Plaques
Lipid-rich atherosclerotic plaques, or "vulnerable plaques" are prone to rupture, causing local intravascular thrombosis, with subsequent grave clinical consequences.
- Conditions
- Atherosclerosis, Aortic Aneurysm, Peripheral Vascular Diseases
- Trial name
- NCT00449306
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Sheba Medical Center
Alzheimer's Disease, Vascular Dementia
Personalized Music Therapy and Agitation in Dementia
Symptoms of agitation include abuse or aggressive behaviour toward self or others, appropriate behaviour performed with inappropriate frequency, or behaviours that are inappropriate according to social standards.
- Trial name
- NCT02147652
- Testing
- Personalized music
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Internal Carotid Artery Stenosis
SONOlysis in Prevention of Brain InfaRctions During Internal Carotid Endarterectomy
SONOBIRDIE Trial is a randomized, single-blind, sham-controlled study designed for a demonstration of the safety and effectiveness of sonolysis (continual transcranial Doppler (TCD) monitoring) in reduction of risk of stroke or…
- Trial name
- SONOBIRDIE (NCT02398734)
- Testing
- sonolysis
- Where
- Czechia
- Volunteers
- 1,492 people
- Sponsor
- University Hospital Ostrava
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.