Clinical trials: Occlusion Carotid
Stroke
Vascular Ultrasound Screening in Patients With Ischemic Cerebrovascular Disease: a Multi-center Registry Study
The purpose of this multicenter study is to investigate the extra-/intra-cranial atherosclerosis distribution pattern in chinese populations with transient ischemic attack and ischemic stroke and analyze the influencing factors…
- Trial name
- NCT02397655
- Where
- China
- Volunteers
- 12,012 people
- Sponsor
- Xuanwu Hospital, Beijing
Carotid Arteriosclerosis, Carotid Stenosis
Residual Stenosis and Restenosis Following Carotid Endarterectomy With Primary Closure, A Prospective Tracking Study
This prospective, multicenter observational study aims to evaluate the incidence, timing, and characteristics of residual and recurrent (restenosis) carotid artery stenosis following carotid endarterectomy (CEA) with primary…
- Conditions
- Carotid Arteriosclerosis, Carotid Stenosis, Brain Stroke
- Trial name
- RECEPT (NCT07057297)
- Where
- Czechia
- Volunteers
- 300 people
- Sponsor
- Charles University, Czech Republic
Carotid Stenosis
Alternative Sensory Presentation Formats in Asymptomatic Carotid Stenosis
Background: In a previous study, information verbally presented as relative risk (e.g. "50% less likely") or qualitative risk (e.g.
- Trial name
- NCT01531868
- Testing
- Video
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Brain Neoplasm, Intracranial Aneurysm
Subclavian Vein catheterization_Seldinger Vs Modified Seldinger
Seldinger technique is a minimally invasive technique in which the practitioner accesses the target vessel with a small bore needle, then dilates to the size required for the catheter.
- Conditions
- Brain Neoplasm, Intracranial Aneurysm, Cerebrovascular Moyamoya Disease
- Trial name
- MS (NCT02090010)
- Testing
- Seldinger technique, Modified Seldinger technique
- Where
- South Korea
- Volunteers
- 418 people
- Sponsor
- Seoul National University Hospital
Acute Ischemic Stroke, Endovascular Thrombectomy
The Prediction of Hemorrhage Transformation by Cerebral Autoregulation in AIS Patient After Endovascular Thrombectomy
This observational study was designed for observe the cerebral hemodynamics and dynamic cerebral autoregulation (dCA) after endovascular thrombectomy (EVT) in acute ischemic stroke (AIS) patients.
- Conditions
- Acute Ischemic Stroke, Endovascular Thrombectomy, Dynamic Cerebral Autoregulation
- Trial name
- PHASE (NCT06361017)
- Testing
- endovascular thrombectomy
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xuanwu Hospital, Beijing
Atherosclerosis
Efficacy and Safety of Simvastatin-ezetimibe Combination Therapy Among Patients With SLE
This is a randomized single-blind trial. This study aimed to determine if intensive lipid-lowering therapy (simvastatin-ezetimibe combination therapy) could reduce the progression of atherosclerosis effectively and safely among…
- Trial name
- NCT02548936
- Testing
- Ezetimibe+Simvastatin Drug Combination
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking Union Medical College Hospital
SLE, Atherosclerosis
Premature Atherosclerosis in Systemic Lupus Erythematosus
Patients with SLE have increased rates of atherosclerosis, while the risk factors for atherosclerosis in those patients were not fully revealed.
- Trial name
- PASLE (NCT04037293)
- Testing
- CIMT and baPWV measurement
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Peking Union Medical College Hospital
Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction
Clinical Impact of Using IMPROVE to Select Patients for Carotid Revascularisation
Narrowing of the carotid artery due to atherosclerosis with an unstable plaque can cause a stroke. Patients with carotid artery disease who have had a TIA or minor stroke and are at high risk of another stroke are often treated…
- Conditions
- Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction, Stroke Ischemic, Atheroscleroses
- Trial name
- IMPROVE (NCT07556887)
- Testing
- IMPROVE Risk Model
- Where
- 10 sites in Netherlands
- Volunteers
- 613 people
- Sponsor
- Maastricht University Medical Center
Carotid Stenosis
Stroke Prevention With Abciximab in Carotid Endarterectomy
In the first portion of the study, the goal will be to determine the safety of the drug Abciximab for use during and in the period after open carotid artery surgery.
- Trial name
- NCT00178451
- Testing
- Abciximab
- Where
- United States
- Sponsor
- University of Rochester
Carotid Artery Stenosis, Atherosclerosis
Aggressive Medical Treatment Evaluation for Asymptomatic Carotid Artery Stenosis
The aim of this study is to determine whether optimal medical treatment can postpone carotid endarterectomy.
- Conditions
- Carotid Artery Stenosis, Atherosclerosis, Stroke
- Trial name
- AMTEC (NCT00805311)
- Testing
- Carotid Endarterectomy, atorvastatin, aspirin, losartan, amlodipine
- Where
- 2 sites in Russia
- Volunteers
- 400 people
- Sponsor
- Russian Cardiology Research and Production Center
Carotid Stenosis
Paraoxonase and LDL Oxidation in Carotid Artery Disease
Atherosclerosis of the carotid arteries is a common cause of stroke. The prevalence and progression of carotid atherosclerosis are believed to be influenced by genetically inherited variations in lipoprotein metabolism.
- Trial name
- NCT00011258
- Testing
- Paraoxonase
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- US Department of Veterans Affairs
Moyamoya Disease, Pediatrics
Effect of Recombinant Human EPO on the Postoperative Neurologic Outcome in Pediatric Moyamoya Patients
This study evaluates the effect of recombinant human erythropoietin (rHuEPO) on the neovascularization of pediatric moyamoya disease patients.
- Conditions
- Moyamoya Disease, Pediatrics, Cerebrovascular Disorders
- Trial name
- NCT03882060
- Testing
- erythropoietin, Normal saline
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Neurology
Assessment of Plaque Vulnerability Using a Novel Technique: Multi-spectral PhotoAcoustic Imaging.
Identification of intraplaque haemorrhage using MRI is technically demanding and sometimes uncomfortable. Photoacoustic imaging is a new non-invasive technique combining multi-wavelength infrared laser light and ultrasound…
- Trial name
- (CVENT-PAI) (NCT04763603)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier St Anne
Atheroscleroses, Rheumatoid Arthritis (RA
Atherosclerosis in Early Rheumatoid Arthritis Patients Using Atherogenic Index of the Plasma and Carotid Intima Media Thickness
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease primarily affecting the peripheral joints, yet its extra-articular burden particularly on the cardiovascular (CV) system has emerged as its most consequential…
- Trial name
- NCT07772466
- Volunteers
- 70 people
- Sponsor
- Assiut University
Moyamoya Disease
Long-term Outcomes of Conservative Management in Patients with Moyamoya Disease and Their First-degree Relatives (LAMORA)
The purpose of this study is to investigate the long-term outcomes of conservative management in patients with moyamoya disease and their first-degree relatives, and provide potential pathogenesis of moyamoya disease.
- Trial name
- NCT05332756
- Testing
- Conservative management
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Beijing Tiantan Hospital
Carotid Artery Stenosis, Ischemic Stroke
Platelet Reactivity and MES During CEA
The purpose of this study is to analyze the association between aspirin efficacy and general platelet reactivity in relation to microembolic signals (MES) during carotid endarterectomy (CEA).
- Conditions
- Carotid Artery Stenosis, Ischemic Stroke, Myocardial Infarction, Aspirin Resistance
- Trial name
- NCT01547039
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- UMC Utrecht
Carotid Artery Stenosis
Evaluation of the 3-in-1 Neuroguard IEP System for Carotid Artery Stenosis
The Neuroguard IEP System is a 3-in-1 carotid stent delivery system consisting of an angioplasty balloon, an integrated embolic protection device and a nitinol self-expanding stent loaded over the balloon and constrained by an…
- Trial name
- PERFORMANCE (NCT04142541)
- Testing
- Neuroguard® IEP 3-in-1 Carotid Stent and Post-Dilation Balloon System with Integrated Embolic Protection (Neuroguard IEP System)
- Where
- 6 sites in Germany, Italy
- Volunteers
- 67 people
- Sponsor
- Contego Medical, Inc.
Stroke, Carotid Stenosis
Distal Versus Proximal Protection on Cerebral Microembolization During High-risk Carotid Artery Stenting
A multicenter, prospective, outcome-assessor-blinded, randomized controlled trial study (MOSCASH) is designed to compare the efficiency of distal and proximal embolism protection devices during carotid angioplasty and stenting…
- Trial name
- MOSCASH (NCT04872127)
- Testing
- proximal embolism protection device, distal embolism protection device
- Where
- China
- Sponsor
- Xuanwu Hospital, Beijing
Coronary Artery Disease, Carotid Artery Stenosis
A Real-World Study on Ultrasound-Based Screening and Integrated Therapeutic Strategies for Patients With Concomitant Coronary and Cervicocephalic Artery Stenosis
This prospective observational cohort study aims to investigate the prevalence and clinical significance of head and neck arterial stenosis in patients with coronary artery disease (CAD) undergoing or scheduled for percutaneous…
- Conditions
- Coronary Artery Disease, Carotid Artery Stenosis, Cerebrovascular Disorders
- Trial name
- ANGEL-UNIFY (NCT07034157)
- Testing
- Percutaneous Coronary Intervention, Cerebrovascular Intervention (CAS ）, No Intervention / Observation
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Beijing Anzhen Hospital
Cerebrovascular Accident, Moyamoya Disease
Quantifying Collateral Perfusion in Cerebrovascular Disease-Moyamoya Disease and Stroke Patients
Quantifying Collateral Perfusion in Cerebrovascular Disease-Moyamoya disease and stroke patients
- Trial name
- NCT01419275
- Testing
- Xenon contrast agent, Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Stanford University