Clinical trials: Occlusion of Artery
Angina Pectoris, Coronary Heart Disease
Effects of Ambient Air Pollution Exposure in Patients With Stable Angina Pectoris During Normal Daily Activities
The purpose of this study is to identify whether exposure to ambient levels of air pollution during normal daily activities has a functional impact on patients with coronary heart disease
- Trial name
- NCT00738491
- Where
- 2 sites in United Kingdom
- Volunteers
- 1 people
- Sponsor
- University of Edinburgh
Coronary Artery Disease
Shockwave Coronary Lithoplasty® Study (Disrupt CAD II)
The objective of this post market study is to examine the safety and performance of the Shockwave Coronary Intravascular Lithotripsy System for the treatment of narrowed coronary arteries before the doctor places a stent.
- Trial name
- NCT03328949
- Testing
- IVL Coronary Lithotripsy System
- Where
- 15 sites in Belgium, Denmark and 7 more
- Volunteers
- 120 people
- Sponsor
- Shockwave Medical, Inc.
Acute Basilar Artery Occlusion, Endovascular Therapy
The Efficacy and Safety of Endovascular Therapy for Acute Ischemic Stroke Due to Large Core Infarction
This study assesses the efficacy and safety of endovascular therapy in patients with acute basilar artery occlusion with large core infarction within a multicenter, prospective, open-label, blinded endpoint, randomized controlled…
- Conditions
- Acute Basilar Artery Occlusion, Endovascular Therapy, Large Core Infarction
- Trial name
- NCT07333950
- Testing
- Endovascular Recanalization Strategy, Best Medical Management
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Beijing Tiantan Hospital
Coronary Artery Disease
Effects of Conditioning Exercises and Resistance Interval Training on Post CABG Patients.
Coronary artery disease (CAD) is a global health challenge influenced by diabetes, hypertension, and psychosocial stress, with women having a higher prevalence of Coronary microvascular disease.
- Trial name
- NCT06844591
- Testing
- Conditioning Exercises/ Aerobic Interval Training, Resistance Interval Training
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Heart Failure, Coronary Artery Disease
3/7 Resistance Training Method in Cardiac Rehabilitation
Aim of the clinical monocentric study is to assess the resistance training exercise intervention in patients with Heart Failure with reduced Ejection Fraction (HFrEF) and coronary artery disease that will best improve peak oxygen…
- Trial name
- NCT05696990
- Testing
- 3/7 Resistance Training Method, 3X9 Resistance Training Method
- Where
- Belgium
- Volunteers
- 112 people
- Sponsor
- Université Libre de Bruxelles
Mitral Valve Insufficiency, Coronary Artery Disease
Comparing the Effectiveness of Repairing Versus Replacing the Heart's Mitral Valve in People With Severe Chronic Ischemic Mitral Regurgitation
People with coronary artery disease (CAD) or people who have had a heart attack may develop a leak in the mitral valve of their heart and may therefore need to undergo surgery to fix the valve.
- Trial name
- NCT00807040
- Testing
- Mitral Valve Repair with Annuloplasty, Mitral Valve Replacement
- Where
- 21 sites in United States, Canada
- Volunteers
- 251 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Peripheral Artery Disease (PAD)
Use of Three-Dimensional Printed Models for Endovascular Planning and Follow-up in Patients Affected by Aorto-Iliac-Femoral-Popliteal Arterial Disease Undergoing Balloon Angioplasty. A Single-center, Single-blind Randomized Controlled Trial
Lower extremity peripheral arterial disease is a major health problem. Currently, balloon angioplasty represents the most commonly performed treatment for patients affected by vascular claudication or critical limb ischemia.
- Trial name
- 3DPAD-1 (NCT07000097)
- Testing
- PTA planning supported by 3D-printed model, PTA (Standard of Care)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Peripheral Arterial Disease, Diabetic Foot Ulcer
Study of PDA-002 in Subjects With Peripheral Arterial Disease and Diabetic Foot Ulcers
This Phase 1, multicenter, open-label, dose-escalation study evaluated the safety and tolerability of intramuscular administration of PDA-002 (human placenta-derived cells) in subjects with peripheral arterial disease (PAD) and…
- Trial name
- NCT01859117
- Testing
- PDA-002
- Where
- 12 sites in United States
- Volunteers
- 15 people
- Sponsor
- Celularity Incorporated
Virtual Reality, Atherosclerosis
Coronary Angiography THerapeutic Virtual Reality
The CATH-VR study will investigate the effect of virtual reality (VR) on patient pain, anxiety, and radial artery vasospasm during coronary angiography.
- Conditions
- Virtual Reality, Atherosclerosis, Coronary Artery Disease, Anxiety
- Trial name
- CATH-VR (NCT03490903)
- Testing
- Virtual Reality, Fentanyl Injection, Midazolam injection
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Atherosclerosis, Peripheral Arterial Disease
Stella Supera Siberia
Endovascular treatment with stenting is currently used in the treatment of femoro-popliteal lesions. This technique tends to extend to lesions for which the gold standard remains until now the open surgery treatment (lesions TASC…
- Conditions
- Atherosclerosis, Peripheral Arterial Disease, Superficial Femoral Artery Occlusion
- Trial name
- NCT03951727
- Testing
- Endovascular treatment for PAD
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Coronary Artery Disease, Coronary Restenosis
Safety and Efficacy of RESTEN-MP When Used in Conjunction With a Bare Metal Stent in Coronary Arteries
The process of re-narrowing of a coronary artery following a revascularization procedure such as angioplasty, begins at the time of the procedure.
- Trial name
- NCT00248066
- Testing
- RESTEN-MP
- Where
- 3 sites in Germany
- Volunteers
- 50 people
- Sponsor
- Sarepta Therapeutics, Inc.
Peripheral Artery Disease, Intermittent Claudication
Assessing Best Medical Treatment Patterns of Patients With Symptomatic Peripheral Arterial Occlusive Disease in Germany
This proposed study will be conducted to support real-world-evidence on the extent of best medical treatment for secondary prevention of patients with symptomatic peripheral arterial occlusive disease (PAOD) for prevention of…
- Conditions
- Peripheral Artery Disease, Intermittent Claudication, Critical Limb Ischemia
- Trial name
- NCT03909022
- Volunteers
- 60,000 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
High Resolution Vessel Wall Imaging, Intracranial Atherosclerotic Stenosis, ICAS
Imaging of Intracranial and Extracranial Arterial Atherosclerotic Plaques Using Different Field Strength MRIs
Atherosclerotic stenosis of the carotid and intracranial arteries is one of the leading causes of ischemic cerebrovascular events worldwide.
- Conditions
- High Resolution Vessel Wall Imaging, Intracranial Atherosclerotic Stenosis, ICAS, Arteriosclerosis
- Trial name
- NCT06754956
- Testing
- The patient will receive two intravenous injections of the same gadoterate meglumine contrast agent.
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Peripheral Arterial Occlusive Disease
Safety and Tolerability of NV1FGF in Patients With Severe Peripheral Artery Occlusive Disease
The primary objective is to evaluate safety and tolerability of single and repeated administrations of escalating doses of NV1FGF administered intramuscularly in patients with severe Peripheral Artery Occlusive Disease (PAOD)…
- Trial name
- NCT01157156
- Testing
- XRP0038 (NV1FGF)
- Where
- 2 sites in United States, Finland
- Volunteers
- 51 people
- Sponsor
- Sanofi
Diabetes Mellitus
Efficacy Study of Pioglitazone Compared to Glimepiride on Coronary Atherosclerotic Disease Progression in Subjects With Type 2 Diabetes Mellitus
The purpose of this study was to determine the efficacy of pioglitazone, once daily (QD), compared to glimepiride on atherosclerotic disease measured by intravascular ultrasound.
- Trial name
- PERISCOPE (NCT00225277)
- Testing
- Pioglitazone, Glimepiride
- Where
- 79 sites in United States, Argentina and 2 more
- Volunteers
- 547 people
- Sponsor
- Takeda
Peripheral Artery Disease
AcoArt Ⅱ/ BTK China: Drug-eluting Balloon for Below-The-Knee Angioplasty Evaluation in China
The purpose of this study is to determine whether DEB is more effective than common PTA balloon using under in long-term vessel patency and inhibiting restenosis in the infrapopliteal artery.
- Trial name
- NCT02137577
- Testing
- DEB catheter, common PTA balloon catheter
- Where
- 11 sites in China
- Volunteers
- 120 people
- Sponsor
- Acotec Scientific Co., Ltd
Peripheral Artery Disease
Exercise Training Versus Best Medical Treatment Only in Peripheral Artery Disease
The aim of the investigators' study is to analyze the value of supervised exercise training combined with medical therapy versus best medical treatment only with respect to quality of life.
- Trial name
- NCT00926081
- Testing
- Supervised exercise training
- Where
- Austria
- Volunteers
- 120 people
- Sponsor
- Medical University of Vienna
Coronary Artery Disease, Angina Pectoris
Impact of Coronary Sinus Flow Reducer on Coronary Microcirculation and Myocardial Ischemia
The increasing number of coronary revascularization procedures, coupled with improvements in drug therapy, has significantly extended the lifespan of patients with coronary artery disease (CAD).
- Trial name
- NCT06266065
- Testing
- Coronary Sinus Reducer
- Where
- Croatia
- Volunteers
- 25 people
- Sponsor
- Clinical Hospital Centre Zagreb
Carotid Artery Stenosis, Carotid Artery Diseases
Study on the Trans-Carotid Artery Occlusion Shunt System Combined With Introducer Sets
The objective of the study is to evaluate the Safety and Efficacy of the Trans-Carotid Artery Occlusion Shunt System Combined with Introducer Sets for Cerebral Protection During Carotid Angioplasty
- Trial name
- NCT06959628
- Testing
- Trans-Carotid Artery Occlusion Shunt System Combined with Introducer Sets
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Shenzhen Wecan Medical Technology Co.,Ltd
Arterial Occlusive Disease, Peripheral Vascular Disease
Study of HGF Via Plasmid Vector to Improve Perfusion in Critical Limb Ischemia
The primary purpose of this study was to assess the overall safety of different dose regimens of AMG0001 (HGF transferred via plasmid vector) as well as evaluate the improvement of blood perfusion in subjects with critical limb…
- Conditions
- Arterial Occlusive Disease, Peripheral Vascular Disease, Ischemia
- Trial name
- NCT00060892
- Testing
- HGF plasmid
- Where
- 24 sites in United States
- Volunteers
- 104 people
- Sponsor
- AnGes USA, Inc.
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