Clinical trials: Occupational Exposure
Body Temperature Changes, Heat Stress
Consecutive Occupational Heat Exposure With and Without Overnight Cooling
Extreme heat events are becoming more frequent, intense, and prolonged, increasing the risk of heat-related illness among workers exposed to hot environments.
- Conditions
- Body Temperature Changes, Heat Stress, Heat Exposure, Heat Fatigue
- Trial name
- NCT07656519
- Testing
- Simulated occupational heat exposure with recovery at recommended indoor temperature limit, Simulated occupational heat exposure with recovery in an overheated indoor environment
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Skin Cancer, Heat Tolerance
Title: ICARUS - Psycho-physiological Profiling of Low and High Heat-resilient Individuals
The escalating environmental heat-stress associated with global warming is a societal challenge with large and potential harmful consequences for humans.
- Conditions
- Skin Cancer, Heat Tolerance, Heat-related Illness, Hyperthermia
- Trial name
- ICARUS (NCT07510061)
- Testing
- Controlled Heat and Ultraviolet Radiation Exposure Protocol
- Where
- 2 sites in Denmark, Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Health Professional
Underreporting of Occupational Blood Exposure (OBE) Among Medical Staff at an University Hospital Center (UHC) in 2017 (OBE PRACTITIONERS UHC 2017)
Regarding 30 to 50% of occupational blood exposure (OBE) are underreporting among health professionals, it's to highlight that the part of medical professionals in OBE reporting is among the lowest (1996 to 2016).
- Trial name
- NCT03424434
- Testing
- Survey diffusion
- Where
- 4 sites in France
- Volunteers
- 1,493 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Pregnancy, Sickness Absence
Active Pregnancy Policy at Work. Greater Wellbeing and Lower Sickness Absence
In a cluster randomized design it will be investigated whether teaching local leaders how to implement active pregnancy policy results in less sickness absence among their pregnant employees.
- Conditions
- Pregnancy, Sickness Absence, Occupational Exposure
- Trial name
- AGp (NCT03002987)
- Testing
- Active Pregnancy policy
- Where
- Denmark
- Volunteers
- 866 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Core Temperature, Heat Stress, Exertional
Initial Stay Times and Heat Mitigation Controls for Uncompensable Occupational Heat Stress - Part II
Workplaces rely on upper heat stress limits provided by the American Conference of Governmental Industrial Hygienists (ACGIH) to manage the health and safety of workers in hot environments.
- Conditions
- Core Temperature, Heat Stress, Exertional, Heat Fatigue, Exercise
- Trial name
- NCT06543719
- Testing
- Simulated work in the heat
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Pneumoconiosis
Pneumoconiosis and Dust Exposure China Cohort
The primary objective of this study is to characterize the demographic and clinical features of patients with occupational pneumoconiosis (hereinafter referred to as pneumoconiosis) in China.
- Trial name
- PANDECT (NCT07077382)
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- China-Japan Friendship Hospital
Hearing Loss, Noise-Induced, Eustachian Tube Dysfunction
Hearing/ET/Vestibular in Balloon Pilots
This study looks at whether working as a hot-air balloon pilot-being exposed to burner noise, changes in air pressure/temperature, and vertical acceleration-is linked to changes in hearing, Eustachian tube function, and…
- Conditions
- Hearing Loss, Noise-Induced, Eustachian Tube Dysfunction, Vestibular Disorders, Occupational Exposure
- Trial name
- FLIGHT-EAR (NCT07200310)
- Testing
- Non-invasive audiologic and vestibular assessments
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Skin Cancer, Occupational Exposure
Virtual Sun Safe Workplaces Ph II (SSW Works)
Americans who work outdoors are exposed to an extreme amount of solar ultraviolet radiation over a lifetime that substantially increases their risk for developing skin cancer.
- Trial name
- NCT05774600
- Testing
- SSW Works, Minimal Information Control
- Where
- United States
- Volunteers
- 543 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
HIV Infections
Behavioral, Clinical and Basic Science Studies of Non-occupational Post-exposure Prophylaxis ("PEP-2")
This is a randomized trial to compare the effect of standard versus enhanced risk reduction counseling on risk behavior incidence in individuals receiving PEP medications.
- Trial name
- PEP-2 (NCT00473018)
- Testing
- standard versus enhanced risk reduction counseling
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cardiovascular Function, Genotoxicity
Health Effects of Occupational Exposure to Combustion Particles - a Study on Volunteers Performing as Train Conductors
Ambient air pollution is a complex mixture of gaseous pollutants and particulate matter (PM). PM has a recognized important role in human health.
- Trial name
- BioTrack (NCT03104387)
- Testing
- Electric train, Diesel train
- Where
- Denmark
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Environmental Exposure, PFAS Exposure
Effect of a Dietary Supplement Versus Placebo on Serum PFAS Levels in Male Firefighters
This study is designed to evaluate the effect of a probiotic dietary supplement containing Streptococcus salivarius on serum PFAS levels in male firefighters with documented occupational PFAS exposure, following twice-daily use…
- Trial name
- AFCRO202 (NCT07846371)
- Testing
- Streptococcus salivarius 46-SL1
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cambiotics ApS
Occupational Exposure
Effects of a 60-min Repeated Trunk Flexion Protocol on Trunk Neuromuscular Properties.
An interventional study on the effects of repeated trunk flexion exposure on trunk neuromuscular properties.
- Trial name
- NCT05511896
- Testing
- Repeated trunk flexion
- Where
- Slovenia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Lymphoma Diffuse Large B-cell
Occupational Exposure to Pesticides in the Prognosis of Lymphomas
The link between the products of synthetic chemistry and cancer is at the heart of much research. Recent work has identified the use of plant protection agents by farmers as a risk factor for developing non-Hodgkin lymphoma…
- Trial name
- ProLyPhy (NCT02898870)
- Where
- France
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Silicosis
Reducing Silica Exposure Among Brick Kiln Workers in Nepal
Inhaling respirable silica increases the risk for silicosis, an incurable and debilitating lung disease. In South Asia, one high-risk industry is brick manufacturing, where more than 4 million manual laborers mold bricks by hand.
- Trial name
- NCT06090370
- Testing
- N95 Respirator, Protective Eyewear, Baseline Survey
- Where
- 3 sites in United States, Nepal
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Parkinson Disease, Secondary
Study on the Relationship Between Environmental and Occupational Exposure to Metals and Parkinson's Disease
The Department of Experimental Medicine - Section of Hygiene, Occupational Medicine, Forensic Medicine of the Second University of Naples, the Section of Neurology of the Second University of Naples and the Mediterranean…
- Trial name
- NCT02588924
- Testing
- Second University of Naples, Neuromed IRCCS
- Where
- 2 sites in Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Occupational Exposure, Musculoskeletal Pain
Can Work be Organized to Become More Health Promoting for Employees in Home Care Services?
This is a two-group, cluster randomized controlled trial designed to assess a health promoting intervention in the home care sector.
- Conditions
- Occupational Exposure, Musculoskeletal Pain, Work-related Injury, Low Back Pain
- Trial name
- GoldiCare (NCT05487027)
- Testing
- Goldilocks work principle
- Where
- 11 sites in Norway
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Body Temperature Changes, Heat Stress
Progressive Heat Exposure and Physiological Strain
Occupational heat-stress guidelines are commonly based on the level of environmental heat exposure and are largely derived from studies conducted under constant environmental conditions.
- Conditions
- Body Temperature Changes, Heat Stress, Heat Exposure, Heat Fatigue
- Trial name
- NCT07847437
- Testing
- Constant Heat Exposure, Progressively Increasing Heat Exposure
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Occupational Exposure
Reducing Chemical Exposures in Nail Salons
In this intervention study, the investigators engage Vietnamese American nail salon owners to train workers within their salons on how to reduce workplace chemical exposures.
- Trial name
- KHOEDEP (NCT03048630)
- Testing
- Education
- Where
- United States
- Volunteers
- 347 people, healthy volunteers welcome
- Sponsor
- Cancer Prevention Institute of California
Healthy Volunteers
Immunogenicity of Recombinant Vesicular Stomatitis Vaccine for Ebola-Zaire (rVSV∆G-ZEBOV-GP Vaccine)
Background: The Ebola virus causes a severe disease that can be fatal. The usual incubation period to illness after being exposed is 2 to 21 days. There are only limited treatments currently available for Ebola infection.
- Trial name
- NCT02788227
- Testing
- rVSV∆G-ZEBOV-GP Vaccine (V920)
- Where
- 3 sites in United States, Canada
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Ergonomics, Occupational Injuries
Effect of the "EMS Back-Up" Ergonomic Program on Paramedics' Manual Handling Safety.
Effect of the "EMS Back-Up" Ergonomic Program on Paramedics' Manual Handling Safety.
- Conditions
- Ergonomics, Occupational Injuries, EMS Exposures or Injuries of EMS Personnel
- Trial name
- NCT07502131
- Testing
- EMS Back-Up Program
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital