Clinical trials: Occupational Exposure
COVID-19, Coronavirus Infection
Beaumont Health Large-scale Automated Serologic Testing for COVID-19
The purpose of this study is to determine how peoples' bodies respond to exposure to COVID-19. Employees of Beaumont Health in Michigan who are older than 18 years may be eligible to participate.
- Conditions
- COVID-19, Coronavirus Infection, Severe Acute Respiratory Syndrome Coronavirus 2
- Trial name
- BLAST COVID-19 (NCT04349202)
- Testing
- EUROIMMUN assay
- Where
- 2 sites in United States
- Volunteers
- 20,614 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Inflammation, Sleep Deprivation
Circadian Rhythm Disruption Effects on Smoke Inhalation
Particulate matter exposure during smoke inhalation provokes inflammatory immune responses in people exposed to burning biomass including fire fighters and civilians.
- Conditions
- Inflammation, Sleep Deprivation, Circadian Rhythm Sleep Disorder, Shift Work Type, Smoke Inhalation
- Trial name
- NCT04955431
- Testing
- Sleep Restriction, Normal Sleep
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Montana
Asbestosis
Oscillation Mechanics of the Respiratory System Asbestos Exposed: Early Diagnosis
Inhalation of dust containing asbestos results in a process of interstitial pulmonary fibrosis called asbestosis. The Forced Oscillation Technique (FOT) evaluates the respiratory mechanics describing resistive, elastic and…
- Trial name
- NCT02280343
- Testing
- evaluated lung function
- Where
- Brazil
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Hearing Loss, Noise-Induced, Hearing Loss
Apple Hearing Study
The Apple Hearing Study is a partnership between the University of Michigan and Apple to study sound exposure and its impact on hearing health.
- Conditions
- Hearing Loss, Noise-Induced, Hearing Loss, Tinnitus
- Trial name
- AHS (NCT04172766)
- Where
- United States
- Volunteers
- 268,037 people, healthy volunteers welcome
- Sponsor
- Apple Inc.
HIV Infections
Behavioral, Clinical and Basic Science Studies of Non-occupational Post-exposure Prophylaxis ("PEP-2")
This is a randomized trial to compare the effect of standard versus enhanced risk reduction counseling on risk behavior incidence in individuals receiving PEP medications.
- Trial name
- PEP-2 (NCT00473018)
- Testing
- standard versus enhanced risk reduction counseling
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Influenza
Safety and Immunogenicity of Vaccine in Adults at Occupational Risk for Influenza A (H5N1) Exposure
The purpose of this study is to characterize the immunogenicity and safety of 3 doses of GSK's avian flu vaccine GSK 1557484A given at different time intervals to adults aged 18 years or greater who are at increased occupational…
- Trial name
- NCT01045564
- Testing
- GSK influenza virus H5N1 vaccine 1557484A
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Sarcoma, Environmental Exposure
Etiosarc: Environmental Aetiology of Sarcomas From a Multicenter French Population-based Case-control Study Among Adults
Introduction: Sarcomas are rare tumors of connective tissue. The exact overall incidence of sarcomas is unknown due to diagnostic difficulties and the various histological subtypes (over 80 subtypes).
- Conditions
- Sarcoma, Environmental Exposure, Occupational Exposure, Life Style
- Trial name
- ETIOSARC (NCT03670927)
- Testing
- Environmental, occupational and lifestyle-related exposures
- Where
- 10 sites in France
- Volunteers
- 2,237 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Sars-CoV2
Longitudinal Study of Covid-19 Infection Among HCW in a French University Hospital
The aim of the study is to determine the incidence o of SARS-cov2 infection among health care workers highly exposed to covid 19 during 10 weeks et to analyze the determinants of their occupational and environmental exposure.
- Trial name
- PRECOVIA (NCT04362267)
- Testing
- self-administered questionnaire, SARS-Cov2 testing
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Cardiovascular Function, Genotoxicity
Health Effects of Occupational Exposure to Combustion Particles - a Study on Volunteers Performing as Train Conductors
Ambient air pollution is a complex mixture of gaseous pollutants and particulate matter (PM). PM has a recognized important role in human health.
- Trial name
- BioTrack (NCT03104387)
- Testing
- Electric train, Diesel train
- Where
- Denmark
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Occupational Exposure to Radiation
Radioprotective Light-weight Caps in the Interventional Cardiology Setting
The primary objective of the present trial is to compare the radiation attenuation provided by XPF caps (0.5mm lead-equivalent and 0.3mm lead-equivalent) to the standard protection (fabric cap, basically no protection) as…
- Trial name
- PROTECT (NCT01620658)
- Testing
- 0.5mm XPF cap, 0.3mm XPF cap, Standard cap
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Baptist Health South Florida
Exposure to Environmental Pollution, Non-occupational
Epigenetic Effect Modifications With Ozone Exposure on Healthy Volunteers
The purpose of this protocol is to assess whether epigenetic factors in healthy individuals make a person more or less responsive to lung inflammation following ozone exposures.
- Trial name
- Geminoz (NCT02469428)
- Testing
- Clean air, Ozone
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
Pesticide Safety
Reducing Farmworkers Exposure to Agricultural Chemicals
The goal of this project is to develop and test the effectiveness of a Lay Health Advisor program to teach migrant and seasonal farmworkers about pesticide safety in their homes.
- Trial name
- NCT00298649
- Testing
- Lay Health Advisor
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Occupational Exposure
Bio Metrology of Nonfibrous Mineral Particles in Bronchoalveolar Lavage Fluids
The main purpose of this study is to update the pulmonary retention values of non-fibrous mineral particles in the general population.
- Trial name
- REACTIT (NCT03917485)
- Where
- France
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Ebola Vaccine
Immunity Induced by VSV-EBOV and Assessment of a Booster Dose in Individuals at Potential Occupational Risk for Exposure
This study is a multi-center, open label, randomized phase 3b trial to assess the durability of Immunity induced by the Ebolavirus Vaccine VSV-EBOV ( with or without booster vaccination) in individuals at potential occupational…
- Trial name
- PREPARE (NCT05959421)
- Testing
- ERVEBO® (rVSV∆G-ZEBOV-GP)
- Where
- 2 sites in Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Internal and External Contamination of Physiotherapists by Antineoplastic Drugs
Occupational Exposure to Antineoplastic Drugs Among Physiotherapists in Healthcare Settings
Many antineoplastic drugs are considered "hazardous to handle" for healthcare professionals, notably because of their carcinogenic, mutagenic and/or reprotoxic effects.
- Trial name
- KINEMAC (NCT07328464)
- Testing
- urine sample, dermal wipe sampling, questionnaires
- Where
- 2 sites in France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Neurologic Symptoms, Neurologic Disorder
" Fume Events in Air Flights: Consequences on Cabin Air Quality and on Aircrews Health of a French Fleet of Aircraft"
The subject of the study focuses on commercial aircraft's cabins air quality, under conditions of both fume events and non-fume events.
- Trial name
- AVISAN (NCT06270095)
- Testing
- Neurocognitive, neuromuscular and neurosensitive tests.
- Where
- France
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Ergonomics, Occupational Injuries
Effect of the "EMS Back-Up" Ergonomic Program on Paramedics' Manual Handling Safety.
Effect of the "EMS Back-Up" Ergonomic Program on Paramedics' Manual Handling Safety.
- Conditions
- Ergonomics, Occupational Injuries, EMS Exposures or Injuries of EMS Personnel
- Trial name
- NCT07502131
- Testing
- EMS Back-Up Program
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Nurses' Occupational Health, Mental Health
Gansu Nurses' Health Cohort Study
This study aims to understand the health status, work stress, and occupational exposure in the work environment among nurses in Gansu Province, China.
- Conditions
- Nurses' Occupational Health, Mental Health, Chronic Diseases, Occupational Exposure
- Trial name
- NCT07645911
- Testing
- Questionnaire Investigation
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- LanZhou University
Human Immunodeficiency Virus
HIV Non-Occupational Post-Exposure Prophylaxis
The purpose of this study is to see if an anti-HIV medication known as Stribild (elvitegravir/cobicistat/emtricitabine/tenofovir DF) is safe, tolerable and acceptable when taken for 28 days, once a day after a possible, sexual…
- Trial name
- QUAD (NCT01855867)
- Testing
- Single Dose Elivitegravir (150mg), Combicistat (150mg), Emtricitabine (200mg), Tenofovir DF (300mg)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kenneth H. Mayer, MD
Occupational Exposure
Air Quality Monitoring and Health Surveillance of Workers in the Photocopier Units
To monitor air quality in selected photocopier units and to assess the health status of workers who are exposed to emissions from photocopiers.
- Trial name
- NCT01289184
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Avinashilingam Deemed University