Clinical trials: Occupational Exposure, open to volunteers
Interstitial Lung Diseases (ILD), Pulmonary Emphysema
Clinical Utility of LIBS Multi-Element Imaging and the IFF Algorithm in Chronic Lung Diseases
PNEUMO-LIBS is a multicenter, non-interventional observational study designed to evaluate whether multi-element tissue imaging by Laser-Induced Breakdown Spectroscopy (LIBS), combined with an artificial intelligence-based…
- Conditions
- Interstitial Lung Diseases (ILD), Pulmonary Emphysema, Chronic Lung Diseases, Occupational Lung Diseases
- Trial name
- PNEUMO-LIBS (NCT07597187)
- Where
- 3 sites in France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Grenoble
Occupational Noise Exposure
OCCUPATIONAL NOISE AND CHEMICAL EXPOSURE EFFECTS ON AUDITORY AND VESTIBULAR FUNCTION
This study aims to investigate the effects of occupational noise exposure on hearing and auditory functions among individuals working in noisy environments.
- Trial name
- NCT07806123
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Nurses' Occupational Health, Mental Health
Gansu Nurses' Health Cohort Study
This study aims to understand the health status, work stress, and occupational exposure in the work environment among nurses in Gansu Province, China.
- Conditions
- Nurses' Occupational Health, Mental Health, Chronic Diseases, Occupational Exposure
- Trial name
- NCT07645911
- Testing
- Questionnaire Investigation
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- LanZhou University
Internal and External Contamination of Physiotherapists by Antineoplastic Drugs
Occupational Exposure to Antineoplastic Drugs Among Physiotherapists in Healthcare Settings
Many antineoplastic drugs are considered "hazardous to handle" for healthcare professionals, notably because of their carcinogenic, mutagenic and/or reprotoxic effects.
- Trial name
- KINEMAC (NCT07328464)
- Testing
- urine sample, dermal wipe sampling, questionnaires
- Where
- 2 sites in France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Noise Exposure, Hearing Loss, Noise-Induced
A Multilevel Intervention to Prevent Noise Exposure in Farmworkers
This study will test a program to reduce noise exposure and prevent hearing loss among farmworkers. Farmworkers are often exposed to high levels of noise from machinery, which can lead to hearing loss over time.
- Conditions
- Noise Exposure, Hearing Loss, Noise-Induced, Occupational Exposure
- Trial name
- POP (NCT07554378)
- Testing
- Multilevel Hearing Protection Training
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Skin Melanoma, Cutaneous Melanoma
Melanoma of the Skin and Exposure to Solar Ultraviolet Radiation at Work in Modena Territory: a Case-control Study to Promote an Active Search and Prevention of Occupational Diseases Based on Recent INAIL Criteria
The goal of this observational study is to learn about the link between work-related sun exposure and a specific type of skin cancer called melanoma in people living in the Modena area, Italy.
- Trial name
- Mesur (NCT07251335)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Modena and Reggio Emilia
PFAS, Environmental Exposures
Use of Bile Acid Binding Resins to Decrease PFAS Levels Via Colesevalem in Veterans Study
The goal of this study is to test the efficacy and feasibility of Colesevelam administration (50% of the recommended dose) to reduce serum PFAS concentration in the Veteran population who have serum PFAS levels that exceed the…
- Conditions
- PFAS, Environmental Exposures, Occupational Exposure to Chemicals, Military Exposure
- Trial name
- PAVERS (NCT07592858)
- Testing
- Colesevelam
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Body Temperature Changes, Heat Stress
Consecutive Occupational Heat Exposure With and Without Overnight Cooling
Extreme heat events are becoming more frequent, intense, and prolonged, increasing the risk of heat-related illness among workers exposed to hot environments.
- Conditions
- Body Temperature Changes, Heat Stress, Heat Exposure, Heat Fatigue
- Trial name
- NCT07656519
- Testing
- Simulated occupational heat exposure with recovery at recommended indoor temperature limit, Simulated occupational heat exposure with recovery in an overheated indoor environment
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Skin Cancer, Heat Tolerance
Title: ICARUS - Psycho-physiological Profiling of Low and High Heat-resilient Individuals
The escalating environmental heat-stress associated with global warming is a societal challenge with large and potential harmful consequences for humans.
- Conditions
- Skin Cancer, Heat Tolerance, Heat-related Illness, Hyperthermia
- Trial name
- ICARUS (NCT07510061)
- Testing
- Controlled Heat and Ultraviolet Radiation Exposure Protocol
- Where
- 2 sites in Denmark, Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Noise Exposure, Noise-induced Hearing Loss
Non-Invasive System to Deliver Therapeutic Hypothermia for Protection Against Noise-Induced Hearing Loss
The goal of this interventional clinical study is to investigate the use of mild therapeutic hypothermia devices for preservation of sensory structures in the cochlea after noise exposure. The main aims of the study are: 1.
- Conditions
- Noise Exposure, Noise-induced Hearing Loss, Noise; Adverse Effect, Mild Therapeutic Hypothermia
- Trial name
- NCT06729632
- Testing
- Cold pack-delivered mild therapeutic hypothermia
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Restorear Devices LLC
Glioblastoma
Key Longitudinal Associations With Risk and Glioblastoma Outcomes
The goal of this observational study is to find out what factors affect the health and risks in adults with glioblastoma (GBM), a grade 4 brain cancer.
- Trial name
- Key LARGO (NCT06625684)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Duke University
Lung Cancer Screening, Military Service-related Environmental and Occupational Exposures
Personalizing Veterans' Lung Cancer Screening and Diagnosis
Lung cancer screening with low-dose chest computed tomography (CT) is currently recommended for high-risk individuals who are 50 to 80 years old, have smoked cigarettes for at least 20 pack-years, and currently smoke or quit…
- Conditions
- Lung Cancer Screening, Military Service-related Environmental and Occupational Exposures, Cancer Survivor, Family History of Lung Cancer
- Trial name
- MAS-EXPAND (NCT07838519)
- Testing
- Low-dose computed tomography
- Where
- 7 sites in United States
- Volunteers
- 1,400 people
- Sponsor
- VA Office of Research and Development
Radiation Exposure to Operator, Endovascular Aortic Repair
Exoskeleton vs. Standard Lead Apron in EVAR Procedures
The goal of this clinical trial is to learn whether an exoskeleton-supported radiation protection system can reduce radiation exposure and musculoskeletal strain in vascular surgeons during endovascular aortic repair procedures…
- Conditions
- Radiation Exposure to Operator, Endovascular Aortic Repair, Musculoskeletal Strain, Occupational Radiation Exposure
- Trial name
- PROTECT-EVAR (NCT07528144)
- Testing
- Exoskeleton-supported radiation protection system, Standard lead apron
- Where
- Poland
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Samodzielny Publiczny Szpital Kliniczny nr 2 PUM
Aging, Mortality
Human Observatory Study
The Human Observatory Study is a prospective observational and ecological surveillance study building a continuously-updating world model for human health, disease, and death at the individual and population level.
- Conditions
- Aging, Mortality, All-cause Mortality, Life Expectancy
- Trial name
- HOS (NCT07646782)
- Testing
- Multi-Domain Ecological and Clinical Data Linkage
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Surgical Smoke Exposure, Occupational Exposure to Surgical Smoke
THE EFFECT OF SURGICAL MASK AND N95 MASK USE ON SURGICAL SMOKE IN OPERATING ROOM NURSES
This study was conducted to compare the effect of surgical mask and N95 mask use on physical symptoms due to surgical smoke in operating theatre nurses.
- Conditions
- Surgical Smoke Exposure, Occupational Exposure to Surgical Smoke, Headache, Dizziness
- Trial name
- NCT07404956
- Testing
- Surgical Mask, N95 Mask
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Lung Cancer
Lung Cancer Screening in a Population Exposed to Occupational Lung Carcinogens
The good clinical practice guidelines for the surveillance of workers after occupational exposure to lung carcinogens were approved by the Haute Autorité de la Santé (French National Authority for Health) and the Institut…
- Trial name
- LUCSO (NCT03562052)
- Where
- 8 sites in France
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Cancer
Occupational Exposures Among Firefighters
This study aims to understand the effect of occupational exposures, including PFAS exposures, among firefighters.
- Trial name
- NCT06173843
- Testing
- PFAS / heavy metal testing, exposures
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Vincere Cancer Center
Work-Related Musculoskeletal Disorders, Ergonomic Risk Exposure
Posture Protection Program for Musculoskeletal Disorders and Ergonomic Risk in Hospital Cleaning Staff
Cleaning work, particularly in hospital settings, is an occupation that demands high physical load on both the musculoskeletal and cardiovascular systems.
- Trial name
- POSKOP (NCT07590453)
- Testing
- Posture Protection Program
- Volunteers
- 60 people
- Sponsor
- Akdeniz University
Plasma Glucose Following Prolonged Heat Exposure
Glycemic Control Following Occupational Work in a Hot Environment
Occupational workers regularly perform physically demanding tasks in hot environments, exposing them to heat stress and potential dehydration.
- Trial name
- NCT06982612
- Testing
- Hot environment, Temperate condition
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Return to Work, Occupational Stress
In Vitro Exposure by VR to Enhance Return to Work After Sick Leave Due to Mental Health Related Complaints
The goal of this pilot randomised controlled trial is to investigate whether in vitro exposure by VR enhances return to work (RTW) in flight cabin crew on sick leave with mental health related complaints.
- Conditions
- Return to Work, Occupational Stress, Self-Efficacy
- Trial name
- NCT06888999
- Testing
- In vitro exposure to workplace by VR plus care as usual, Care as usual: Guidance from occupational physician and psychologist focused on returning to work
- Where
- Netherlands
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)