Clinical trials: Occupational Injuries
Work Related Upper Limb Disorder, Musculoskeletal Pain
SeniorWorkingLife (Danish Title: SeniorArbejdsLiv)
Due to demographic changes across Europe there are strong political interests in maintaining the labour force by prolonging working life, i.e. increasing retirement age.
- Conditions
- Work Related Upper Limb Disorder, Musculoskeletal Pain, Work Accident, Work Injury
- Trial name
- SAL2018 (NCT03634410)
- Where
- Denmark
- Volunteers
- 30,000 people
- Sponsor
- National Research Centre for the Working Environment, Denmark
Siderosis
A Prospective Safety Follow Up Study Of Subjects Enrolled In Study A4321001 And Who Have Received Drug Product
This protocol intends to detail investigations necessary to evaluate the ocular safety of subjects enrolled in study A4321001 and who have received formulated Drug Product (Lot 8716-098).
- Trial name
- NCT00471224
- Testing
- Observational Trial
- Where
- 3 sites in United States
- Volunteers
- 16 people
- Sponsor
- Pfizer
Spinal Cord Injuries
Motor Learning Approach for Manual Wheelchair Users
The overall purpose of this project is to pilot test a manual wheelchair (MWC) training program based on motor learning theory to improve wheelchair propulsion for manual wheelchair users (MWUs) with spinal cord injury (SCI).
- Trial name
- NCT03781609
- Testing
- Roller system group (RG), Overground group (OG)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Washington University School of Medicine
Decompression Sickness, Pulmonary Edema - Acute
Epidemiological Assessment of Technical Diving Accidents in Mainland France and Factors Predictive of Severity (TEKCare)
This retrospective study aims at an epidemiological description of the clinical presentation of medical problems in technical diving.
- Conditions
- Decompression Sickness, Pulmonary Edema - Acute, Oxygen Toxicity, Carbon Dioxide Poisoning
- Trial name
- TEKCare (NCT06627153)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Brest
Siderosis, Neurological Disorder
Audiovestibular Function in Infratentorial Superficial Siderosis
One in six people in the United Kingdom and over 400 million people worldwide have disabling hearing loss. This figure will double by 2050 as predicted by the World Health Organisation.
- Conditions
- Siderosis, Neurological Disorder, Rare Diseases, Age Related Hearing Loss
- Trial name
- AViSS (NCT04200664)
- Testing
- Hearing assessment, Vestibular/balance assessment, Quality of life assessment
- Where
- 2 sites in United Kingdom
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University College, London
Gulf War Syndrome
Glutamate Neuro-Excitotoxicity in GWI
The objective of the proposed research is to examine whether dietary exposure to food additives containing glutamate may be contributing to symptoms in Gulf War Illness (GWI).
- Trial name
- GWI (NCT03342482)
- Testing
- Low-glutamate diet
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- American University
Pneumoconiosis
The Experience of Patients and Family Caregivers in Managing Pneumoconiosis in the Family Context
This is an exploratory qualitative study to understand the needs of patients with pneumoconiosis, and the care-giving experience of their family caregivers.
- Trial name
- NCT04022902
- Testing
- No intervention
- Where
- Hong Kong
- Volunteers
- 83 people
- Sponsor
- Chinese University of Hong Kong
Burnout, Caregiver, Burnout, Professional
Frontline Clinician Psilocybin Study
This study aims to investigate the effects of a single dose of psilocybin, delivered in the contextof pre- and post-dose psychotherapy, on symptoms of depression and burnout suffered by healthcare clinicians as a result of…
- Conditions
- Burnout, Caregiver, Burnout, Professional, COVID-19, Depression
- Trial name
- NCT05163496
- Testing
- Psilocybin (Usona Institute)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Washington
Occupational Injuries, Heat Stress
Effect of Rapid Heat Stress on Firefighters Musculoskeletal Injury Risk
This study will examine the effect of heat stress on factors that influence musculoskeletal injury risk in firefighters. Participants will attend 4 data collection sessions. 1: informed consent, screening, and familiarization.
- Conditions
- Occupational Injuries, Heat Stress, Leg Injury, Back Injuries
- Trial name
- NCT06442956
- Testing
- Rapid Heat Condition, Gradual Heat Condition
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Burns, Hand Burn
Effect of Task Oriented Training and Xbox KinectTM on Hand Function in Pediatric Burn
The Jebsen-Taylor Hand Function Test and Canadian Occupational Performance Measure (COPM) were considered as primary outcome measurements.
- Trial name
- HandBurn (NCT04497103)
- Testing
- control, Xbox kinect, task oriented training
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Qassim University
Inflammation, Sleep Deprivation
Circadian Rhythm Disruption Effects on Smoke Inhalation
Particulate matter exposure during smoke inhalation provokes inflammatory immune responses in people exposed to burning biomass including fire fighters and civilians.
- Conditions
- Inflammation, Sleep Deprivation, Circadian Rhythm Sleep Disorder, Shift Work Type, Smoke Inhalation
- Trial name
- NCT04955431
- Testing
- Sleep Restriction, Normal Sleep
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Montana
Occupational Diseases, Occupational Lung Disease
Multifaceted Intervention for Protection Against Cotton Dust Exposure Among Textile Workers
Textile workers are exposed to various harmful substances during work, including cotton dust, which is the dust present in air during the handling or processing of cotton.
- Trial name
- MultiTex-RCT (NCT03738202)
- Testing
- Multifaceted intervention package
- Where
- Pakistan
- Volunteers
- 2,031 people
- Sponsor
- Aga Khan University
Asbestos Exposure
Investigation of the Anti-Cancer Activity of Artichoke Extract in an Asbestos-Exposed Population
This is a single-arm phase II trial to assess the biological activity (in a sub-cohort using a Simon two-stage Phase II design) and toxicity of Artichoke Whole Phytocomplex Concentrate (WPC).
- Trial name
- ABOCA1 (NCT02076672)
- Testing
- Artichoke WPC
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)
Post-traumatic Stress Disorder, Persian Gulf Syndrome
Sentra AM® and Sentra PM® for Post-traumatic Stress Disorder (PTSD) and Gulf War Fibromyalgia (GWF)
An open-label clinical outcomes study to determine the safety and efficacy of Sentra AM® and Sentra PM® for post-traumatic stress disorder (PTSD) and Gulf War fibromyalgia (GWF).
- Trial name
- GWF001 (NCT01437891)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stephanie Pavlik
Posttraumatic Stress Disorder, Depressive Symptoms
Written Exposure Therapy for Nurses
Nurses often experience elevated levels of stress, overwork, and trauma in the workplace, leading to posttraumatic stress disorder (PTSD), depression, burnout, and even nurse turnover.
- Conditions
- Posttraumatic Stress Disorder, Depressive Symptoms, Burn Out, Anxiety
- Trial name
- NCT06432374
- Testing
- WET
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Texas at Austin
Flexor Tendon Rupture, Thumb Osteoarthritis
Occupational Therapy Pre-operative Education in the Orthopedic Hand Setting
This will be a prospective randomized control trial with a blocking method to determine the effect of an occupational therapy focused pre-operative education on 3 pre-determined diagnosis: Carpometacarpal (CMC) Arthroplasty…
- Conditions
- Flexor Tendon Rupture, Thumb Osteoarthritis, Distal Radius Fracture
- Trial name
- NCT05095415
- Testing
- Occupational Therapy Pre-operative Consult, Typical Pre-Operative Education
- Sponsor
- Methodist University, North Carolina
Viral Hepatitis C
Hepatitis C Virus Post-Exposure Prophylaxis for Health Care Workers
To assess the safety and tolerability of the use of telaprevir in the setting of post-exposure prophylaxis among HCW exposed to HCV genotype 1 or genotype 2.
- Trial name
- NCT01766115
- Testing
- Telaprevir
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Exposure to Ionizing Radiation, Occupational Exposure to Radiation
Use of Large Field of View During Image Acquisition for Coronary Angiography
Coronary angiography exposes patients and physicians to ionizing radiation. The purpose of this study is to evaluate the routine use of large field of view during image acquisition for coronary angiography.
- Conditions
- Exposure to Ionizing Radiation, Occupational Exposure to Radiation, Radiation Injury
- Trial name
- XRay Reduction (NCT01334931)
- Testing
- Large field of view arm, Medium field of view
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Occupational Diseases
Hazardous Substances Injuries
This clinical study aims to evaluate the effectiveness and safety of [intervention or treatment] in patients with [clinical condition].
- Trial name
- Substances (NCT07879261)
- Testing
- Retrospective Administrative Data Assessment
- Where
- Israel
- Volunteers
- 1,951 people
- Sponsor
- Sergio Gabriel Susmallian
Spine Health, Spine Injuries and Disorders
Occupational Exposure to Whole Body Vibration Among U.S. Military Veterans: Acute and Chronic Contributions to Musculoskeletal Disorders and Spine-Area Pain
Significance to VA: There is a lack of prospective longitudinal studies investigating the relationship between risk factors to Veterans and development and progression of musculoskeletal (MSK) spine injury and pain.
- Conditions
- Spine Health, Spine Injuries and Disorders, Spine Degeneration, Whole Body Vibration
- Trial name
- NCT07367139
- Testing
- Water
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Milwaukee VA Medical Center