Clinical trials: Ocd
Autism, Asperger's Syndrome
Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders
Autism spectrum disorders affect as many as 1 out of 150 children and are related to significant impairment in social, adaptive, and school functioning.
- Conditions
- Autism, Asperger's Syndrome, Generalized Anxiety Disorder, Social Phobia
- Trial name
- NCT01178385
- Testing
- Cognitive-behavioral therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Body Dysmorphic Disorder, Obsessive-compulsive Disorder
Oxytocin Administration in BDD and OCD
The purpose of the current study is to investigate the effect of an acute administration of intranasal oxytocin, relative to placebo, on social cognitive impairments among individuals with body dysmorphic disorder and…
- Trial name
- NCT02671266
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Obsessive-Compulsive Disorder
A Controlled Trial of Daily Cognitive-Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder
Pediatric obsessive-compulsive disorder (OCD) is a chronic and often disabling illness with an estimated lifetime prevalence of 1 to 3%.
- Trial name
- NCT00369642
- Testing
- Cognitive-behavioral therapy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Depression Disorders, Bipolar Affective Disorder
Epidemiological Study on the Prevalence of Mental Disorders in Slovakia
This study maps the current epidemiological situation of mental disorders in Slovakia. The aim of the study is to determine the prevalence of selected mental disorders in the adult population of the Slovak Republic, assess the…
- Conditions
- Depression Disorders, Bipolar Affective Disorder, Generalized Anxiety Disorder (GAD), Panic Disorder
- Trial name
- EpiMentDisSK (NCT07129408)
- Where
- Slovakia
- Volunteers
- 3,100 people, healthy volunteers welcome
- Sponsor
- Comenius University
Obsessive-Compulsive Disorder
Neuroimaging Biomarkers for Predicting rTMS Response in OCD
This study evaluates an accelerated schedule of theta-burst stimulation using a Transcranial Magnetic Stimulation (TMS) device for treatment-resistant Obsessive Compulsive Disorder (OCD).
- Trial name
- NCT04286126
- Testing
- Active bilateral DMPFC, Active right-sided OFC
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obsessive Compulsive Disorder
Computer Assisted Cognitive Behavior Therapy for Obsessive Compulsive Disorder: A Comprehensive Stepped-Care Approach
The goal of this project is to improve access to effective treatments for obsessive compulsive disorder (OCD) through the use of web-based cognitive behavioral therapy (CBT) treatment.
- Trial name
- NCT01522287
- Testing
- Computer-Assisted Cognitive Behavior Therapy (BT STEPS)
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Center for Psychological Consultation
Hoarding Disorder, Virtual Reality Based Therapy
Non-Immersive Virtual Environments for the Treatment of Hoarding Disorder
This experimental trial investigates whether Virtual Reality Exposure (VRe) helps individuals reduce the difficulty of discarding personal possessions. It will also evaluate the psychological state impacts of the intervention.
- Conditions
- Hoarding Disorder, Virtual Reality Based Therapy, General Population (no Specific Condition or Disease)
- Trial name
- HD&VR (NCT07160543)
- Testing
- Imagination Exposure, Non-immersive Virtual Reality Exposure
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Padova
Obsessive-Compulsive Disorder
Control and Reward Circuits in Obsessive Compulsive Disorder
The purpose of this study is to examine the brain functioning of OCD patients and healthy controls before and after treatment with Exposure and Response Prevention (EXRP) therapy.
- Trial name
- NCT02221518
- Testing
- Exposure & Response Prevention (EX/RP)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)
Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS)
Background: PANS is an illness that comes on suddenly in children. The full name is Pediatric Acute-Onset Neuropsychiatric Syndrome. It can cause sudden obsessive-compulsive behaviors.
- Trial name
- NCT03507218
- Where
- 8 sites in United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Obsessive-Compulsive Disorder
Characterization of Childhood-Onset Obsessive-Compulsive Disorder
The purpose of this study is to learn more about Obsessive-compulsive Disorder (OCD) in children. OCD usually has a slow onset, and symptoms that may remain at a stable level over time.
- Trial name
- NCT00044239
- Where
- 4 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Autism, Asperger's Syndrome
Computer- Assisted Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders
This study will examine the efficacy of a computerized cognitive behavioral therapy (CCBT) program for children with anxiety and autism spectrum disorders.
- Conditions
- Autism, Asperger's Syndrome, Generalized Anxiety Disorder, Social Phobia
- Trial name
- CCAL (NCT01565629)
- Testing
- Computer assisted cognitive behavioral therapy.
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
The Role of Cognitive Control in the Transdiagnostic Conceptualization of "Intrusive Thoughts"
The investigators are examining whether difficulties with cognitive control (i.e., the ability to stop one's thought process and shift attention) is a common problem across three types of repetitive, negative thinking: obsessions…
- Conditions
- Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Major Depressive Disorder
- Trial name
- NCT03414619
- Testing
- Cognitive Control Tasks and Script Driven Imagery
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Obsessive-Compulsive Disorder
Reinforcement Learning and Obsessive-compulsive Disorder: Exploring the Role of the Orbitofrontal Cortex
Obsessive-compulsive disorder (OCD) is a neuropsychiatric condition affecting 1-3% of the population. Typically, symptoms start in adolescence or early adulthood, are time-consuming, and have a significant impact on quality of…
- Trial name
- NEUROCOMP (NCT06566781)
- Where
- Portugal
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Fundacao Champalimaud
Obsessive-Compulsive Disorder
Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD
The proposed randomized, double-blind research study will use functional magnetic resonance neuroimaging using state-of-the-art HCP acquisition protocols and analytic pipelines, to identify predictors and correlates of response…
- Trial name
- NCT04131829
- Testing
- Fluoxetine - immediate treatment, Fluoxetine - delayed treatment
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yale University
Obsessive-compulsive Disorder
D-cycloserine Augmentation of Cognitive Behavioral Therapy (CBT) for Pediatric Obsessive-compulsive Disorder (OCD)
The investigators are conducting a randomized double-blind placebo-controlled study to assess the efficacy of d-cycloserine augmentation of cognitive-behavioral therapy for the treatment of pediatric obsessive compulsive…
- Trial name
- NCT01411774
- Testing
- Cognitive-behavioral therapy, d-cycloserine
- Where
- 2 sites in United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Obsessive-Compulsive Disorder
Development of Adaptive Deep Brain Stimulation for OCD
This research study is for participants that have been diagnosed with intractable Obsessive -compulsive disorder (OCD). OCD is a persistent and oftentimes disabling disorder marked by unwanted and distressing thoughts…
- Trial name
- Phase Ib (NCT04281134)
- Testing
- Summit RC+S System, One Month Blinded Discontinuation Period:
- Where
- 3 sites in United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Obsessive-Compulsive Disorder
Effectiveness of a Self-guided Mobile Application in Improving Obsessive Compulsive Disorder Symptoms
Obsessive Compulsive Disorder (OCD) is a significant mental health problem worldwide. OCD typically begins in young adulthood, and without adequate intervention, often takes a chronic course.
- Trial name
- NCT06202677
- Testing
- Self-guided program on obsessive compulsive disorder, Self-guided program on cooperation
- Where
- Singapore
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Obsessive Compulsive Disorder
Deep Brain Stimulation of NAc/ALIC to Prevent Treatment-Refractory Obsessive Compulsive Disorder
Nucleus accumbens/anterior limb of internal capsule play important roles in the process of treatment-refractory obsessive compulsive disorder, deep brain stimulation of nucleus accumbens/anterior limb of internal capsule will…
- Trial name
- NCT02601677
- Testing
- Deep brain stimulation, Fluoxetine
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Anxiety Disorder, Obsessive-Compulsive Disorder
Definitive Selection of Neuroimaging Biomarkers in Anxiety Disorder and Obsessive-compulsive Disorder: A Longitudinal Functional Magnetic Resonance Imaging （fMRI） Study With Paroxetine Treatment
To explore reliable neuroimaging biomarkers for anxiety disorder and OCD,and whether there are shared imaging biomarkers between different subtypes of anxiety disorder and OCD, the investigators included30 drug-naive general…
- Trial name
- NCT03894085
- Testing
- Paroxetine
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Central South University
Obsessive Compulsive Disorder (OCD)
Transcranial Direct Current Stimulation and Extinction in Obsessive Compulsive Disorder
Obsessive-compulsive disorder (OCD) is associated with substantial impairments in quality of life and is among the most disabling psychiatric disorders.
- Trial name
- NCT06834217
- Testing
- Active transcranial direct current stimulation
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Yale University