Clinical trials: Ocd
Pediatric Bipolar Disorder, Pediatric OCD
Fluoxetine for Obsessive-Compulsive Disorder in Children and Adolescents With Bipolar Disorder
This will be a 12-week open-label pilot treatment study for children and adolescents (ages 6-17) who meet DSM-IV criteria for bipolar disorder (BPD) and obsessive-compulsive disorder (OCD) who are adequately mood stabilized on a…
- Trial name
- NCT00592852
- Testing
- fluoxetine
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Massachusetts General Hospital
Obsessive-Compulsive Disorder, OCD
pBFS Guided rTMS Therapy for Treatment-resistant Obsessive-Compulsive Disorder
The investigators aim to evaluate the safety and efficacy of pBFS-guided rTMS therapy targeting DLPFC for patients with treatment-resistant Obsessive-Compulsive Disorder.
- Trial name
- NCT05964049
- Testing
- active rTMS treatment
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Changping Laboratory
OCD
Cerebral and Cognitive Markers of Treatment Resistance in Obsessive Compulsive Disorder
This study aims to define individual profiles of treatment resistants in order to find indicators and predictors of the therapeutic response.
- Trial name
- 3TOC (NCT05843604)
- Testing
- Functional MRI
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Henri Laborit
Obsessive-Compulsive Disorder
Priming in Repetitive Transcranial Magnetic Stimulation in the Treatment of Obsessive Compulsive Disorder
Obsessive Compulsive Disorder results in high social impact, affecting quality of life and tending to a chronic course. A considerable proportion of patients, up tp 60%, remain with symptoms even thought treatment is…
- Trial name
- NCT06049706
- Testing
- Active Priming
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Suellen Andrade
Skin-Picking, Acne
Digital Strategies for Patients With Chronic Dermatosis With Pruritus / Skin Picking Disorder
Almost 35% of patients treated to dermatosis have some psychiatric disorder. The aim of this study is to evaluate the prevalence and severity of skin picking disorder and other dermatosis, and also test the efficacy of an…
- Conditions
- Skin-Picking, Acne, Dermatosis
- Trial name
- NCT04731389
- Testing
- internet-based cognitive-behavioral therapy, Quality of life improving intervention
- Where
- Brazil
- Volunteers
- 163 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Obsessive-Compulsive Disorder
Predicting Treatment Response in Patients With OCD
This study consists of a naturalistic follow-up of subjects with Obsessive-Compulsive Disorder (OCD) that have participated in a global study investigating brain signatures of OCD funded by the National Institutes of Mental…
- Trial name
- NCT03993535
- Testing
- selective serotonin reuptake inhibitor
- Where
- 4 sites in United States, Brazil and 2 more
- Volunteers
- 250 people
- Sponsor
- University of Sao Paulo
Obsessive-Compulsive Disorder
Ventral Capsulotomy for Intractable OCD
Obsessive-compulsive disorder impacts 1-2 percent of the population. Unfortunately, about fifteen percent of patients fail to benefit from existing therapies.
- Trial name
- NCT05659082
- Testing
- Laser Interstitial Thermal Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Butler Hospital
Anxiety Disorders, Obsessive-Compulsive Disorder
HANDS-ON: a Personalized, Brief and Intensive Exposure-based Intervention for Youth With Persistent Anxiety or OCD
A substantial part of children/adolescents with anxiety or obsessive-compulsive disorder (AD/OCD) do not profit substantially from first-choice treatment (i.e., cognitive behavioral therapy; CBT).
- Conditions
- Anxiety Disorders, Obsessive-Compulsive Disorder, Obsessive-Compulsive Disorder in Children, Obsessive-Compulsive Disorder in Adolescence
- Trial name
- NCT06152913
- Testing
- HANDS-ON treatment
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Accare
Obsessive-Compulsive Disorder
Deep Brain Stimulation (DBS) for the Treatment of Refractory Obsessive-compulsive Disorder (OCD)
Deep brain stimulation for treatment resistant deep brain stimulation
- Trial name
- NCT04217408
- Testing
- Deep brain stimulation
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Sunnybrook Health Sciences Centre
Obsessive-Compulsive Disorder
What Are You Looking for? Psychometric and Experimental Analyses of Reassurance Seeking in Obsessive-compulsive Disorder
This study evaluates the efficacy and acceptability of two cognitive-behavioural interventions for reassurance seeking behaviour in obsessive-compulsive disorder (OCD), a family accommodation reduction protocol vs.
- Trial name
- NCT02909660
- Testing
- Cognitive-behavioural therapy
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- Concordia University, Montreal
Obsessive-Compulsive Disorder
The Use of Magnetic Brain Stimulation to Treat Obsessive Compulsive Disorder, a Pilot Study
The purpose of this study is two-fold: first, to observe the effect of one session of repetitive transcranial magnetic stimulation (rTMS) on the error-prediction abilities of patients with obsessive compulsive disorder (OCD) as…
- Trial name
- NCT02541812
- Testing
- Transcranial Magnetic Stimulation
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Tourette's Syndrome, Tourette Syndrome
Subthalamic Stimulation in Tourette's Syndrome
The main objective of this project is to evaluate the efficacy of subthalamic nucleus deep brain stimulation (STN DBS) in treating motor and phonic tics in medically refractory Tourette's syndrome (TS).
- Conditions
- Tourette's Syndrome, Tourette Syndrome, Gilles de la Tourette Syndrome, Tourette Disorder
- Trial name
- STN-DBSinTS (NCT02619084)
- Testing
- STN DBS
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Depression - Major Depressive Disorder, Bipolar
Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health Trajectories
Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health (BLOOM) is a project that aims to overcome age and diagnostic boundaries to generate person-specific longitudinal profiles of mental…
- Conditions
- Depression - Major Depressive Disorder, Bipolar, Psychosis, Eating Disorder NOS
- Trial name
- BLOOM (NCT06978452)
- Where
- Canada
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Obsessive-Compulsive Disorder
Function-metabolism Coupling in Decision-making Confidence Neural Network of Obsessive-compulsive Disorder
This study, a case-control study, aims to investigate the function-metabolism coupling in decision-making confidence neural network of obsessive-compulsive disorder.
- Trial name
- NCT05563935
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Obsessive - Compulsive Disorder
Neural Mechanisms of the Sensorymotor Circuit in Sensory Phenomena in OCD
The goal of this clinical study is to investigate the neural mechanisms of abnormal sensory phenomena in patients with Obsessive-Compulsive Disorder and to evaluate whether modulation of the insula-supplementary motor area…
- Trial name
- NCT07480408
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Trichotillomania, Excoriation (Skin-Picking) Disorder
Internet CBT for Trichotillomania and Skin Picking Disorder
The primary aim of the study is to test the feasibility, safety and efficacy of a manual based, Internet-delivered, behavior therapy (I-BT) for trichotillomania and skin picking disorder.
- Trial name
- NCT04559750
- Testing
- Internet delivered behavior therapy (I-BT)
- Where
- Sweden
- Volunteers
- 25 people
- Sponsor
- Karolinska Institutet
Obsessive-Compulsive Disorder
Enhancement of Therapeutic Learning in OCD Using tDCS
Psychiatric disorders characterized by pathological fear and anxiety are common and often disabling. Despite their limitations, exposure therapies are among the most efficacious treatments for these disorders.
- Trial name
- NCT03572543
- Testing
- tDCS
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Yale University
Obsessive Compulsive Disorder
Overlapping Neural Circuits in Pediatric OCD
The purpose of this study is to examine the brain functioning of children and adolescent with OCD before and after treatment with Exposure and Response Prevention (EXRP) therapy.
- Trial name
- NCT02421315
- Testing
- CBT treatment for OCD based on Exposure & Response Prevention (EX/RP) and when indicated medication treatment
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Obsessive-Compulsive Disorder
Deep Brain Stimulation in Severe Obsessive-compulsive Disorder
Deep brain stimulation is an established treatment for movement disorders. New indications for deep brain stimulation are under investigation, among them severe and treatment-resistant obsessive-compulsive disorder.
- Trial name
- DBS in OCD (NCT04919785)
- Testing
- Deep brain stimulation
- Volunteers
- 11 people
- Sponsor
- University Hospital, Umeå
Hoarding Disorder, Virtual Reality Based Therapy
Non-Immersive Virtual Environments for the Treatment of Hoarding Disorder
This experimental trial investigates whether Virtual Reality Exposure (VRe) helps individuals reduce the difficulty of discarding personal possessions. It will also evaluate the psychological state impacts of the intervention.
- Conditions
- Hoarding Disorder, Virtual Reality Based Therapy, General Population (no Specific Condition or Disease)
- Trial name
- HD&VR (NCT07160543)
- Testing
- Imagination Exposure, Non-immersive Virtual Reality Exposure
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Padova