Clinical trials: Ocd
Trichotillomania
Telepsychotherapy for the Treatment of Adolescents With Trichotillomania
The primary purpose of the current study is to evaluate the effectiveness of providing treatment for adolescents with trichotillomania through the use of telehealth.
- Trial name
- NCT03725163
- Testing
- Acceptance and Commitment Therapy Enhanced Behavior Therapy (AEBT)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Utah State University
Obsessive-Compulsive Disorder
Safety and Efficacy of Pramipexole Treatment in Resistant Obsessive-Compulsive Disorder (OCD)
The most common and effective treatment for OCD is pharmacological therapy that includes selective serotonin reuptake inhibitors (SSRIs) antidepressants and, in the case of patients resistant to this approach, a combination with…
- Trial name
- OCD-RT (NCT06611592)
- Testing
- Pramipexole 0.088mg/tid, Pramipexole 0.18 mg/tid, Pramipexole 0.35 mg/tid
- Where
- Portugal
- Volunteers
- 48 people
- Sponsor
- Clinical Academic Center (2CA-Braga)
Obsessive Compulsive Disorder, Trichotillomania
Developing Effective Response Inhibition Training for Symptom Relief in OCD and Trichotillomania
Obsessive-compulsive disorder (OCD) and its related disorders (e.g., trichotillomania) are characterized by the marked difficulty in inhibiting unwanted or inappropriate responses.
- Trial name
- NCT02059980
- Testing
- Response inhibition training
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Wisconsin, Milwaukee
Obsessive-Compulsive Disorder
Efficacy Study of add-on Therapy With N-Acetylcysteine in Resistant Obsessive-compulsive Disorder
The primary objective of this study is to determine if N-Acetylcysteine (NAC) has efficacy as an augmentation agent in the treatment of treatment-resistant obsessive-compulsive disorder (OCD).
- Trial name
- NACTOC (NCT01555970)
- Testing
- N-Acetylcysteine (NAC)
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Hoarding Disorder, Hoarding
Neuromodulation for Comorbid Hoarding Disorder and Depression
The primary goal of this study is to evaluate whether intermittent theta burst stimulation (iTBS) is effective for treating depression in people who have depression and chronic hoarding disorder (HD).
- Conditions
- Hoarding Disorder, Hoarding, Depression
- Trial name
- NCT05985356
- Testing
- iTBS
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of California, San Diego
Obsessive Compulsive Disorder
Cost-Effectiveness of Adding Web-Based Cognitive-Behavioral Therapy (CBT) to Luvox CR for Obsessive Compulsive Disorder (OCD)
This study will test the hypotheses that: 1. 12 weeks of Luvox-CR plus web-based Cognitive-Behavioral Therapy (CBT) [CT-STEPS] will produce greater symptom relief of OCD than treatment with Luvox-CR alone; and, 2.
- Trial name
- NCT00743834
- Testing
- Luvox CR, Behavioral Therapy
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rogers Center for Research & Training, Inc.
Obsessive Compulsive Disorder
N-methyl Glycine (Sarcosine) for the Treatment of Obsessive Compulsive Disorder (OCD)
Several lines of evidence implicate glutamatergic dysfunction in the pathophysiology of obsessive compulsive disorder (OCD). Sarcosine, also known as N-methylglycine, is an endogenous antagonist of glycine transporter-I (GlyT-I)…
- Trial name
- NCT01031927
- Testing
- N-methyl glycine
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- China Medical University Hospital
Hoarding Disorder
Augmenting Buried in Treasures Workshop (BIT) With In-home Decluttering Practice for Individuals With Hoarding Disorder
Patients participate in Buried in Treasures Workshop (BIT) that has been shown to improve symptoms of hoarding disorder. To target levels of clutter, the investigators are testing an intervention to add in-home decluttering…
- Trial name
- NCT02377986
- Testing
- BIT+in-home decluterring, In-Home Decluttering
- Volunteers
- 5 people
- Sponsor
- New York State Psychiatric Institute
Hoarding Disorder
Imaginal Exposure for Hoarding Disorder
The present study will test a potential new treatment strategy, imaginal exposure, for hoarding disorder. Although cognitive behavioral therapy often reduces hoarding, some people do not want to start, or cannot handle, that…
- Trial name
- NCT03734705
- Testing
- Imaginal Exposure Writing, Neutral Writing
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Stanford University
Obsessive Compulsive Disorder
Transcranial Magnetic Stimulation (TMS) in Obsessive Compulsive Disorder (OCD): Mechanisms and Biomarkers
The purpose of this study is to test the efficacy of 1-Hz repetitive transcranial magnetic stimulation (TMS) over the pre-supplementary motor area as a treatment for obsessive compulsive disorder.
- Trial name
- TMSOCD (NCT02355002)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Massachusetts General Hospital
Obsessive-Compulsive Disorder
Sonication-based OCD Neurosurgical Intervention Via Capsulotomy
The goal of this clinical trial is to determine if ExAblate MR-guided Focused Ultrasound (MRgFUS) bilateral anterior capsulotomy can be used safely and effectively to relieve symptoms of moderate to severe obsessive compulsive…
- Trial name
- SONIC (NCT06131502)
- Testing
- ExAblate MR-guided Focused Ultrasound Bilateral Anterior Capsulotomy
- Where
- 2 sites in United States
- Volunteers
- 66 people
- Sponsor
- Brigham and Women's Hospital
Parkinson's Disease, Obsessive Compulsive Disorder
Physiological Brain Atlas Development
The NIH grant has funded the development of a physiological brain atlas registry that will allow us to significantly improve the data collectioin and use of physiological data into a normalized brain volume.
- Conditions
- Parkinson's Disease, Obsessive Compulsive Disorder, Dystonia, Essential Tremor
- Trial name
- Brain Atlas (NCT00575081)
- Testing
- Stereotactic brain procedures
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Vanderbilt University Medical Center
Obsessive-Compulsive Disorder
Randomized Controlled Trial of Standard ERP and OC-Go
Phase II of this study will examine the efficacy of the OC-Go application via a randomized controlled trial comparing standard exposure and response prevention (ERP) treatment for pediatric obsessive compulsive disorder (OCD) to…
- Trial name
- OC-GoPhaseII (NCT03601312)
- Testing
- Exposure and Response Prevention, OC-Go
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of California, Los Angeles
Obsessive-Compulsive Disorder, Anxiety
Music Therapy in Obsessive Compulsive Disorder
Previous studies have highlighted the potential therapeutic benefits of receptive individual music therapy as an adjunct to standard care, in a variety of psychiatric ailments including mood and anxiety disorders.
- Conditions
- Obsessive-Compulsive Disorder, Anxiety, Depression
- Trial name
- NCT02314195
- Testing
- Selective serotonin re-uptake inhibitor, Cognitive Behavioral Therapy, Music therapy
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Islamic Azad University, Marvdasht
Skin-Picking
Skin Picking Approach Avoidance Task
Pathological skin picking (PSP) is conceptualized as a behavioral addiction. Research has shown that behavioral addictions (e.g., problematic alcoholism or smoking) can be reduced using a cognitive retraining tool called…
- Trial name
- SPAAT (NCT04099537)
- Testing
- Computerized cognitive training
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Wisconsin, Milwaukee
PTSD, Autism Spectrum Disorder High-Functioning
Psychiatric Orders in Psychoanalytic Treatment of ASD
Autism Spectrum Disorder (ASD) is often accompanied by a variety of other symptoms, such as bipolar disorder, Attention Deficit Hyperactivity Disorder (ADHD), Social Anxiety Disorder (SAD), Avoidant Personality Disorder (AvPD)…
- Conditions
- PTSD, Autism Spectrum Disorder High-Functioning, OCD, Agoraphobia With Panic Attacks
- Trial name
- NCT05930912
- Testing
- Psychoanalysis, sertraline 50mg, Duloxetine 20 MG
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Yang I. Pachankis, PhD
Obsessive-Compulsive Disorder
SMART ERP for the Behavioral Treatment of Youth With Obsessive Compulsive Disorder (OCD)
This randomized pilot study examines a graduated behavioral treatment approach for youth with obsessive compulsive disorder. Youth will be randomized to receive treatment in the community or at the hospital.
- Trial name
- NCT03672565
- Testing
- Phase One: Standardized Brief Intensive ERP, Phase Two: Flexible Patient Driven Intensive ERP, Follow-Up Phase: Booster Calls
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Obsessive-Compulsive Disorder, Cognitive Behavioral Therapy
Cognitive Behavioral Group Treatment for Obsessive-compulsive Disorder in Youth
Obsessive-compulsive disorder (OCD) is a debilitating disorder characterized by unwanted intrusive thoughts and disrupting repetitive rituals.
- Conditions
- Obsessive-Compulsive Disorder, Cognitive Behavioral Therapy, Adolescent
- Trial name
- NCT04891367
- Testing
- Cognitive behavioral therapy
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Aarhus University Hospital
Obsessive-Compulsive Disorder
A Wearable AI Feedback Tool for Pediatric OCD
To test the feasibility of implementing digitally enhanced psychotherapy and research in a community child and adolescent mental health center including the acceptability of the digital technology to patients, parents and…
- Trial name
- NCT05064527
- Testing
- wearable biosensor, Treatment as usual (TAU), Exposure and response prevention (ERP)
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Obsessive Compulsive Disorder
Internet Cognitive Behavior Therapy (CBT) for Obsessive Compulsive Disorder (OCD)
The main aim of this study is to test whether cognitive behavior therapy could be effective in treating obsessive compulsive disorder.
- Trial name
- NCT01348529
- Testing
- Internet CBT
- Where
- Sweden
- Volunteers
- 23 people
- Sponsor
- Karolinska Institutet